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protein_kinase
Euk-VirPithovirus_sibericum
protein_kinase__YP_009001060__Pithovirus_sibericum__1450746
Identity
- Accession:
- YP_009001060 ↗
- Protein ID:
- protein_kinase
- Kingdom:
- euk
Quality
71.2
mean pLDDT
Taxonomy
Bamfordvirae›
Nucleocytoviricota›
Megaviricetes›
Pimascovirales›
Pithoviridae›
Alphapithovirus›
Pithovirus_sibericum
TaxID: 1450746
Cluster
View cluster (9 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 1-63
Domain cluster:
representative
CATH (70)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1zarA02 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.87 | 81.0 | 7.34e-01 | 100.0% | 92.6% |
| 2nryD01 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.83 | 75.0 | 6.61e-01 | 100.0% | 84.8% |
| 2clqA01 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.82 | 74.0 | 6.68e-01 | 100.0% | 84.7% |
| 3f7wA01 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.81 | 73.0 | 6.43e-01 | 100.0% | 100.0% |
| 3lzhA01 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.80 | 72.0 | 6.30e-01 | 98.4% | 100.0% |
| 6ziwI01 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.80 | 71.0 | 6.59e-01 | 98.4% | 85.9% |
| 5iqaA01 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.79 | 71.0 | 6.23e-01 | 98.4% | 100.0% |
| 6ctzA01 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.77 | 69.0 | 6.05e-01 | 100.0% | 96.8% |
| 4q5eA01 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.77 | 70.0 | 6.58e-01 | 100.0% | 96.0% |
| 4lrjA01 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.76 | 69.0 | 6.58e-01 | 100.0% | 94.5% |
| 3havA01 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.75 | 67.0 | 5.97e-01 | 100.0% | 97.8% |
| 3mmlF01 | 3.30.1360.40 | Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › | 0.74 | 60.0 | 5.55e-01 | 87.3% | 73.4% |
| 3va7A05 | 3.30.1360.40 | Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › | 0.73 | 64.0 | 5.51e-01 | 98.4% | 80.0% |
| 4feuF01 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.73 | 65.0 | 6.19e-01 | 98.4% | 91.8% |
| 5ih0A01 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.73 | 63.0 | 5.58e-01 | 98.4% | 95.7% |
| 5ighA01 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.72 | 60.0 | 5.49e-01 | 96.8% | 77.3% |
| 1b4bA00 | 3.30.1360.40 | Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › | 0.70 | 57.0 | 5.48e-01 | 88.9% | 81.7% |
| 7xhzA01 | 3.30.1240.10 | Alpha Beta › 2-Layer Sandwich › Hypothetical Protein, Haloacid Dehalogenase-like Hydrolase; Chain: A; domain 2 › | 0.70 | 58.0 | 4.66e-01 | 92.1% | 91.9% |
| 1xxaC00 | 3.30.1360.40 | Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › | 0.69 | 55.0 | 5.29e-01 | 88.9% | 80.8% |
| 6vudA02 | 3.30.1360.40 | Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › | 0.69 | 58.0 | 5.51e-01 | 93.7% | 92.0% |
| 6gmhK00 | 3.30.1360.10 | Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › RNA polymerase, RBP11-like subunit | 0.68 | 54.0 | 4.52e-01 | 88.9% | 57.4% |
| 4on1A01 | 2.40.128.470 | Mainly Beta › Beta Barrel › Lipocalin › | 0.68 | 60.0 | 4.66e-01 | 100.0% | 72.7% |
| 5xu6C01 | 3.30.200.110 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Inositol-pentakisphosphate 2-kinase, N-lobe | 0.67 | 60.0 | 5.02e-01 | 100.0% | 82.4% |
| 3pgvA02 | 3.30.1240.10 | Alpha Beta › 2-Layer Sandwich › Hypothetical Protein, Haloacid Dehalogenase-like Hydrolase; Chain: A; domain 2 › | 0.67 | 56.0 | 4.80e-01 | 93.7% | 89.1% |
| 4dw8A02 | 3.30.1240.10 | Alpha Beta › 2-Layer Sandwich › Hypothetical Protein, Haloacid Dehalogenase-like Hydrolase; Chain: A; domain 2 › | 0.67 | 55.0 | 4.65e-01 | 92.1% | 89.6% |
| 1nrwA02 | 3.30.1240.10 | Alpha Beta › 2-Layer Sandwich › Hypothetical Protein, Haloacid Dehalogenase-like Hydrolase; Chain: A; domain 2 › | 0.66 | 56.0 | 4.42e-01 | 93.7% | 91.5% |
| 1ohvA01 | 3.90.1150.10 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 | 0.66 | 57.0 | 4.19e-01 | 96.8% | 41.6% |
| 5suhA02 | 3.30.70.1710 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › BMC (bacterial microcompartment) domain | 0.66 | 51.0 | 4.43e-01 | 87.3% | 79.6% |
| 1rz1A00 | 2.30.110.10 | Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A | 0.65 | 54.0 | 4.15e-01 | 93.7% | 76.3% |
| 3a8uX01 | 3.90.1150.10 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 | 0.64 | 55.0 | 4.11e-01 | 96.8% | 45.0% |
| 3l7yA02 | 3.30.1240.10 | Alpha Beta › 2-Layer Sandwich › Hypothetical Protein, Haloacid Dehalogenase-like Hydrolase; Chain: A; domain 2 › | 0.64 | 53.0 | 4.49e-01 | 93.7% | 89.0% |
| 1nf2A02 | 3.30.1240.10 | Alpha Beta › 2-Layer Sandwich › Hypothetical Protein, Haloacid Dehalogenase-like Hydrolase; Chain: A; domain 2 › | 0.64 | 53.0 | 4.49e-01 | 92.1% | 89.6% |
| 1k8kD02 | 3.30.1460.20 | Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, › | 0.64 | 54.0 | 4.36e-01 | 98.4% | 50.4% |
| 4zglD00 | 3.30.428.10 | Alpha Beta › 2-Layer Sandwich › HIT family, subunit A › HIT-like | 0.63 | 56.0 | 4.81e-01 | 100.0% | 86.3% |
| 4h5bA00 | 3.30.1460.70 | Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, › | 0.63 | 53.0 | 4.14e-01 | 100.0% | 61.2% |
| 1kzlA02 | 2.40.30.20 | Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › | 0.63 | 49.0 | 4.27e-01 | 87.3% | 56.4% |
| 2qg3A00 | 3.30.1960.10 | Alpha Beta › 2-Layer Sandwich › SSo0622-like fold › tRNA wybutosine-synthesizing-like | 0.63 | 54.0 | 3.86e-01 | 98.4% | 86.6% |
| 1js3A03 | 3.90.1150.10 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 | 0.63 | 52.0 | 4.61e-01 | 96.8% | 67.0% |
| 1lc5A01 | 3.90.1150.10 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 | 0.63 | 52.0 | 4.25e-01 | 95.2% | 48.0% |
| 4zevA02 | 3.30.1240.10 | Alpha Beta › 2-Layer Sandwich › Hypothetical Protein, Haloacid Dehalogenase-like Hydrolase; Chain: A; domain 2 › | 0.62 | 51.0 | 4.35e-01 | 92.1% | 88.8% |
| 4e1oA03 | 3.90.1150.10 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 | 0.62 | 52.0 | 4.56e-01 | 96.8% | 66.3% |
| 2b30A02 | 3.30.1240.10 | Alpha Beta › 2-Layer Sandwich › Hypothetical Protein, Haloacid Dehalogenase-like Hydrolase; Chain: A; domain 2 › | 0.61 | 50.0 | 4.22e-01 | 92.1% | 81.7% |
| 3aawA02 | 3.30.2130.10 | Alpha Beta › 2-Layer Sandwich › VC0802-like › VC0802-like | 0.61 | 47.0 | 3.53e-01 | 85.7% | 40.0% |
| 1jyaB00 | 3.30.1460.10 | Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, › | 0.60 | 51.0 | 4.25e-01 | 100.0% | 68.6% |
| 3mpoA02 | 3.30.1240.10 | Alpha Beta › 2-Layer Sandwich › Hypothetical Protein, Haloacid Dehalogenase-like Hydrolase; Chain: A; domain 2 › | 0.60 | 52.0 | 4.40e-01 | 98.4% | 77.6% |
| 2lpuA00 | 3.30.1460.50 | Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, › | 0.60 | 50.0 | 3.95e-01 | 100.0% | 72.3% |
| 4wp3C00 | 3.30.70.1230 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain | 0.59 | 50.0 | 3.59e-01 | 95.2% | 67.4% |
| 2ebbA00 | 3.30.1360.20 | Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › Transcriptional coactivator/pterin dehydratase | 0.59 | 48.0 | 4.32e-01 | 96.8% | 71.9% |
| 2djwA01 | 3.30.70.920 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Lrp/AsnC effector binding domain/regulation of amino acid metabolism (RAM) domain | 0.58 | 44.0 | 4.24e-01 | 84.1% | 75.7% |
| 1rkqA02 | 3.30.1240.10 | Alpha Beta › 2-Layer Sandwich › Hypothetical Protein, Haloacid Dehalogenase-like Hydrolase; Chain: A; domain 2 › | 0.58 | 51.0 | 4.32e-01 | 100.0% | 74.8% |
| 1usmA00 | 3.30.1360.20 | Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › Transcriptional coactivator/pterin dehydratase | 0.58 | 49.0 | 4.61e-01 | 95.2% | 88.3% |
| 5erdB05 | 2.60.40.60 | Mainly Beta › Sandwich › Immunoglobulin-like › Cadherins | 0.57 | 46.0 | 3.99e-01 | 85.7% | 64.9% |
| 3i5tB01 | 3.90.1150.10 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 | 0.57 | 47.0 | 3.65e-01 | 100.0% | 48.2% |
| 2dt9A01 | 3.30.70.260 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain | 0.57 | 43.0 | 4.18e-01 | 87.3% | 81.1% |
| 3hlzB01 | 3.40.1000.10 | Alpha Beta › 3-Layer(aba) Sandwich › Protein Transport Mog1p; Chain A › Mog1/PsbP, alpha/beta/alpha sandwich | 0.56 | 49.0 | 3.85e-01 | 100.0% | 79.3% |
| 1lxjA00 | 3.30.70.930 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.56 | 40.0 | 3.51e-01 | 82.5% | 47.6% |
| 1ju2A02 | 3.30.410.40 | Alpha Beta › 2-Layer Sandwich › Cholesterol Oxidase; domain 2 › | 0.56 | 43.0 | 3.22e-01 | 88.9% | 65.7% |
| 1k3sA00 | 3.30.1460.10 | Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, › | 0.55 | 45.0 | 3.94e-01 | 100.0% | 57.4% |
| 6u9hF02 | 3.30.70.1150 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT-like. Chain A, domain 2 | 0.55 | 39.0 | 3.75e-01 | 84.1% | 63.6% |
| 2pofA00 | 3.30.428.30 | Alpha Beta › 2-Layer Sandwich › HIT family, subunit A › HIT family - CDH-like | 0.55 | 47.0 | 3.32e-01 | 100.0% | 33.2% |
| 1s5jA03 | 3.90.1600.10 | Alpha Beta › Alpha-Beta Complex › Palm domain of DNA polymerase › B family DNA polymerase, palm domain | 0.55 | 44.0 | 3.35e-01 | 90.5% | 81.5% |
| 4nzjA03 | 2.60.40.1180 | Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II | 0.54 | 47.0 | 4.31e-01 | 100.0% | 96.6% |
| 5mmjh01 | 3.30.1370.30 | Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › | 0.54 | 43.0 | 4.10e-01 | 90.5% | 84.0% |
| 2lnjA00 | 3.40.1000.10 | Alpha Beta › 3-Layer(aba) Sandwich › Protein Transport Mog1p; Chain A › Mog1/PsbP, alpha/beta/alpha sandwich | 0.54 | 44.0 | 3.43e-01 | 100.0% | 68.2% |
| 1vdxA00 | 3.90.1140.10 | Alpha Beta › Alpha-Beta Complex › Cyclic Phosphodiesterase; Chain: A, › Cyclic phosphodiesterase | 0.54 | 39.0 | 2.92e-01 | 79.4% | 96.7% |
| 3a5vA02 | 2.60.40.1180 | Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II | 0.54 | 45.0 | 4.02e-01 | 100.0% | 96.0% |
| 1t8hA00 | 3.60.140.10 | Alpha Beta › 4-Layer Sandwich › CNF1/YfiH-like putative cysteine hydrolases › CNF1/YfiH-like putative cysteine hydrolases | 0.54 | 45.0 | 3.07e-01 | 100.0% | 98.5% |
| 2y3vD00 | 2.170.210.20 | Mainly Beta › Beta Complex › Dna Repair Protein Xrcc4; Chain: A, domain 1 › Spindle assembly abnormal protein 6, N-terminal domain | 0.53 | 43.0 | 3.31e-01 | 92.1% | 96.1% |
| 3cc1A02 | 2.60.40.1180 | Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II | 0.51 | 43.0 | 3.90e-01 | 96.8% | 94.3% |
| 4dezA01 | 3.30.70.270 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain | 0.51 | 39.0 | 3.51e-01 | 88.9% | 64.6% |
ECOD (84)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5027718 | 206.1.1.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase | 0.88 | 77.0 | 5.40e-01 | 98.4% | 32.8% |
| 5061296 | 206.1.1.9 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › RIO1 | 0.88 | 81.0 | 5.21e-01 | 100.0% | 53.1% |
| 3591361 | 206.1.1.9 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › RIO1 | 0.87 | 81.0 | 5.08e-01 | 100.0% | 32.9% |
| 3185940 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.83 | 75.0 | 4.81e-01 | 100.0% | 28.0% |
| 3732119 | 206.1.1.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase | 0.83 | 76.0 | 5.80e-01 | 100.0% | 47.4% |
| 5010657 | 206.1.1.9 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › RIO1 | 0.82 | 76.0 | 5.42e-01 | 100.0% | 43.5% |
| 3585647 | 206.1.1.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase | 0.82 | 76.0 | 4.71e-01 | 100.0% | 39.0% |
| 3280548 | 306.6.1.0 ↗ | a+b two layers › Glucose permease domain IIB-like › PH0987 N-terminal domain-like › PH0987 N-terminal domain-like | 0.80 | 62.0 | 5.68e-01 | 87.3% | 65.0% |
| 4004448 | 206.1.1.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase | 0.79 | 73.0 | 4.50e-01 | 100.0% | 23.0% |
| 4851660 | 206.1.1.67 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › HopBF1_kinase | 0.79 | 70.0 | 5.08e-01 | 100.0% | 44.0% |
| 3503058 | 206.1.1.52 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › YrbL-PhoP_reg | 0.79 | 70.0 | 4.98e-01 | 100.0% | 40.5% |
| 3217221 | 206.1.2.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › SAICAR synthase › SAICAR_synt | 0.79 | 70.0 | 4.58e-01 | 100.0% | 30.6% |
| 3275983 | 206.1.2.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › SAICAR synthase › SAICAR_synt | 0.79 | 71.0 | 4.51e-01 | 100.0% | 28.3% |
| 3984011 | 206.1.1.33 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › OspG_kinase | 0.78 | 71.0 | 5.06e-01 | 100.0% | 41.1% |
| 3689719 | 206.1.1.11 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › APH | 0.78 | 71.0 | 4.48e-01 | 100.0% | 23.1% |
| 4964061 | 206.1.1.15 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Fructosamin_kin | 0.77 | 69.0 | 4.47e-01 | 100.0% | 23.3% |
| 3262615 | 206.1.1.49 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › DUF5898 | 0.77 | 69.0 | 5.09e-01 | 100.0% | 65.0% |
| 1515972 | 206.1.1.33 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › OspG_kinase | 0.76 | 69.0 | 5.04e-01 | 100.0% | 42.3% |
| 3634756 | 206.1.1.11 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › APH | 0.76 | 69.0 | 4.51e-01 | 100.0% | 26.2% |
| 3955923 | 306.6.1.1 ↗ | a+b two layers › Glucose permease domain IIB-like › PH0987 N-terminal domain-like › PH0987 N-terminal domain-like › CT_C_D | 0.75 | 61.0 | 5.50e-01 | 87.3% | 68.2% |
| 4527337 | 206.1.2.4 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › SAICAR synthase › Ins_P5_2-kin | 0.75 | 66.0 | 4.30e-01 | 100.0% | 34.9% |
| 3178660 | 206.1.2.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › SAICAR synthase › SAICAR_synt | 0.74 | 67.0 | 4.21e-01 | 100.0% | 33.1% |
| 3287406 | 306.6.1.1 ↗ | a+b two layers › Glucose permease domain IIB-like › PH0987 N-terminal domain-like › PH0987 N-terminal domain-like › CT_C_D | 0.72 | 61.0 | 5.64e-01 | 93.7% | 72.5% |
| 3786722 | 206.1.2.3 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › SAICAR synthase › IPK | 0.72 | 62.0 | 3.86e-01 | 96.8% | 18.4% |
| 1016844 | 306.2.1.1 ↗ | a+b two layers › Glucose permease domain IIB-like › arginine repressor C terminal domain-related › C-terminal domain of arginine repressor › Arg_repressor_C | 0.71 | 57.0 | 5.33e-01 | 88.9% | 73.8% |
| 5011633 | 3012.1.1.0 ↗ | a+b two layers › Cof C2 cap domain › Cof C2 cap domain › Cof C2 cap domain | 0.71 | 61.0 | 5.15e-01 | 93.7% | 66.3% |
| 4032715 | 3012.1.1.0 ↗ | a+b two layers › Cof C2 cap domain › Cof C2 cap domain › Cof C2 cap domain | 0.71 | 60.0 | 4.76e-01 | 92.1% | 90.4% |
| 5006044 | 206.1.1.268 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › DUF6206 | 0.71 | 62.0 | 4.01e-01 | 100.0% | 27.1% |
| 4552919 | 306.2.1.1 ↗ | a+b two layers › Glucose permease domain IIB-like › arginine repressor C terminal domain-related › C-terminal domain of arginine repressor › Arg_repressor_C | 0.70 | 56.0 | 5.13e-01 | 88.9% | 70.6% |
| 4307373 | 4354.1.1.1 ↗ | a+b two layers › TRCF domain › TRCF domain › TRCF domain › TRCF | 0.70 | 61.0 | 4.56e-01 | 96.8% | 81.3% |
| 4392066 | 306.6.1.2 ↗ | a+b two layers › Glucose permease domain IIB-like › PH0987 N-terminal domain-like › PH0987 N-terminal domain-like › FlgI | 0.69 | 53.0 | 5.08e-01 | 88.9% | 70.7% |
| 4567824 | 310.2.1.1 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF › RRF | 0.68 | 58.0 | 4.08e-01 | 93.7% | 36.4% |
| 1309460 | 3338.1.1.1 ↗ | a+b two layers › Fragilysin-3 prodomain-like › Fragilysin-3 prodomain › Fragilysin-3 prodomain › fragilysinNterm | 0.68 | 60.0 | 4.63e-01 | 100.0% | 70.6% |
| 4263825 | 310.2.1.1 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF › RRF | 0.68 | 56.0 | 4.03e-01 | 93.7% | 38.4% |
| 5057765 | 4955.1.1.0 ↗ | a+b two layers › permuted ferredoxin-like domain in yeast RNA-polymerase beta-prime subunit › permuted ferredoxin-like domain in yeast RNA-polymerase beta-prime subunit › permuted ferredoxin-like domain in yeast RNA-polymerase beta-prime subunit | 0.68 | 54.0 | 5.04e-01 | 88.9% | 81.2% |
| 3200626 | 310.2.1.1 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF › RRF | 0.67 | 56.0 | 3.96e-01 | 93.7% | 39.5% |
| 5029252 | 242.1.1.7 ↗ | a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_3 | 0.67 | 56.0 | 4.51e-01 | 92.1% | 54.2% |
| 4962382 | 873.1.1.0 ↗ | a+b complex topology › H-NOX domain › H-NOX domain › H-NOX domain | 0.67 | 56.0 | 4.68e-01 | 93.7% | 55.5% |
| 5008417 | 873.1.1.0 ↗ | a+b complex topology › H-NOX domain › H-NOX domain › H-NOX domain | 0.67 | 56.0 | 4.50e-01 | 93.7% | 50.4% |
| 4523817 | 310.2.1.1 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF › RRF | 0.67 | 56.0 | 3.96e-01 | 93.7% | 36.4% |
| 2075906 | 3012.1.1.4 ↗ | a+b two layers › Cof C2 cap domain › Cof C2 cap domain › Cof C2 cap domain › Hydrolase_3 | 0.67 | 55.0 | 4.65e-01 | 92.1% | 89.6% |
| 1878743 | 3016.1.1.0 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases | 0.64 | 54.0 | 4.73e-01 | 96.8% | 71.0% |
| 4427482 | 3016.1.1.0 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases | 0.64 | 53.0 | 4.54e-01 | 96.8% | 58.2% |
| 3596774 | 225.1.1.0 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0.64 | 55.0 | 4.49e-01 | 98.4% | 80.0% |
| 4888552 | 3016.1.1.9 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › OKR_DC_1 | 0.64 | 54.0 | 4.20e-01 | 96.8% | 70.8% |
| 3815332 | 304.9.1.84 ↗ | a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › PF28975 | 0.64 | 49.0 | 3.90e-01 | 82.5% | 42.4% |
| 5039467 | 304.165.1.0 ↗ | a+b two layers › Alpha-beta plaits › Uncharacterized protein Ta1207 › Uncharacterized protein Ta1207 | 0.64 | 51.0 | 3.78e-01 | 88.9% | 77.1% |
| 4032021 | 3012.1.1.0 ↗ | a+b two layers › Cof C2 cap domain › Cof C2 cap domain › Cof C2 cap domain | 0.64 | 52.0 | 4.46e-01 | 92.1% | 91.4% |
| 5029881 | 310.3.1.26 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › General secretion pathway protein M (EpsM) periplasmic domain-related › General secretion pathway protein M (EpsM) periplasmic domain-related › HVO_2525_N | 0.64 | 51.0 | 3.98e-01 | 90.5% | 49.7% |
| 3500240 | 3016.1.1.0 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases | 0.64 | 52.0 | 4.44e-01 | 95.2% | 56.4% |
| 3801312 | 3016.1.1.0 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases | 0.63 | 52.0 | 4.70e-01 | 95.2% | 68.9% |
| 4217176 | 3016.1.1.0 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases | 0.63 | 51.0 | 4.53e-01 | 95.2% | 62.0% |
| 222386 | 241.1.1.6 ↗ | a+b two layers › Type III secretory system chaperone-like › Type III secretory system chaperone › Type III secretory system chaperone › YbjN | 0.63 | 53.0 | 4.14e-01 | 100.0% | 61.2% |
| 3247221 | 3016.1.1.4 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › Pyridoxal_deC | 0.63 | 52.0 | 4.28e-01 | 96.8% | 52.0% |
| 4933548 | 4955.1.1.0 ↗ | a+b two layers › permuted ferredoxin-like domain in yeast RNA-polymerase beta-prime subunit › permuted ferredoxin-like domain in yeast RNA-polymerase beta-prime subunit › permuted ferredoxin-like domain in yeast RNA-polymerase beta-prime subunit | 0.63 | 51.0 | 4.70e-01 | 88.9% | 70.0% |
| 5008353 | 241.1.1.0 ↗ | a+b two layers › Type III secretory system chaperone-like › Type III secretory system chaperone › Type III secretory system chaperone | 0.61 | 54.0 | 4.37e-01 | 98.4% | 73.3% |
| 3761601 | 304.9.1.84 ↗ | a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › PF28975 | 0.61 | 50.0 | 4.41e-01 | 88.9% | 65.6% |
| 4946604 | 3016.1.1.0 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases | 0.61 | 51.0 | 4.97e-01 | 96.8% | 91.4% |
| 1115806 | 3016.1.1.0 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases | 0.61 | 49.0 | 4.35e-01 | 93.7% | 61.2% |
| 3603763 | 242.1.1.7 ↗ | a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_3 | 0.61 | 48.0 | 4.36e-01 | 90.5% | 66.7% |
| 3598887 | 304.8.1.0 ↗ | a+b two layers › Alpha-beta plaits › ACT-like › ACT-like | 0.60 | 45.0 | 4.34e-01 | 82.5% | 73.3% |
| 5012467 | 310.3.1.0 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › General secretion pathway protein M (EpsM) periplasmic domain-related › General secretion pathway protein M (EpsM) periplasmic domain-related | 0.60 | 53.0 | 4.44e-01 | 100.0% | 80.0% |
| 4938715 | 306.2.1.0 ↗ | a+b two layers › Glucose permease domain IIB-like › arginine repressor C terminal domain-related › C-terminal domain of arginine repressor | 0.60 | 48.0 | 4.41e-01 | 88.9% | 77.6% |
| 2075999 | 3012.1.1.4 ↗ | a+b two layers › Cof C2 cap domain › Cof C2 cap domain › Cof C2 cap domain › Hydrolase_3 | 0.60 | 52.0 | 4.40e-01 | 98.4% | 77.6% |
| 3951221 | 242.1.1.0 ↗ | a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases | 0.60 | 48.0 | 4.46e-01 | 92.1% | 68.2% |
| 5013819 | 3012.1.1.0 ↗ | a+b two layers › Cof C2 cap domain › Cof C2 cap domain › Cof C2 cap domain | 0.60 | 47.0 | 4.73e-01 | 88.9% | 87.7% |
| 4116365 | 880.1.1.1 ↗ | a+b duplicates or obligate multimers › ADC synthase › ADC synthase › ADC synthase › Chorismate_bind | 0.59 | 44.0 | 2.67e-01 | 87.3% | 10.0% |
| 4060228 | 305.2.1.1 ↗ | a+b two layers › DCoH-like › Pterin-4a-carbinolamine dehydratase (PCD)/dimerization cofactor of HNF1 (DCoH) › Pterin-4a-carbinolamine dehydratase (PCD)/dimerization cofactor of HNF1 (DCoH) › Pterin_4a | 0.59 | 50.0 | 4.17e-01 | 95.2% | 64.5% |
| 4937732 | 305.2.1.1 ↗ | a+b two layers › DCoH-like › Pterin-4a-carbinolamine dehydratase (PCD)/dimerization cofactor of HNF1 (DCoH) › Pterin-4a-carbinolamine dehydratase (PCD)/dimerization cofactor of HNF1 (DCoH) › Pterin_4a | 0.58 | 48.0 | 4.39e-01 | 96.8% | 76.7% |
| 4119008 | 305.2.1.1 ↗ | a+b two layers › DCoH-like › Pterin-4a-carbinolamine dehydratase (PCD)/dimerization cofactor of HNF1 (DCoH) › Pterin-4a-carbinolamine dehydratase (PCD)/dimerization cofactor of HNF1 (DCoH) › Pterin_4a | 0.58 | 48.0 | 4.27e-01 | 93.7% | 72.6% |
| 4152393 | 305.2.1.1 ↗ | a+b two layers › DCoH-like › Pterin-4a-carbinolamine dehydratase (PCD)/dimerization cofactor of HNF1 (DCoH) › Pterin-4a-carbinolamine dehydratase (PCD)/dimerization cofactor of HNF1 (DCoH) › Pterin_4a | 0.58 | 49.0 | 4.16e-01 | 95.2% | 67.6% |
| 3839295 | 3012.1.1.0 ↗ | a+b two layers › Cof C2 cap domain › Cof C2 cap domain › Cof C2 cap domain | 0.58 | 47.0 | 4.61e-01 | 93.7% | 91.4% |
| 4106395 | 216.1.1.0 ↗ | a+b two layers › UBC-like › UBC-like › UBC-like | 0.56 | 40.0 | 3.44e-01 | 77.8% | 70.9% |
| 5011011 | 3012.1.1.0 ↗ | a+b two layers › Cof C2 cap domain › Cof C2 cap domain › Cof C2 cap domain | 0.56 | 43.0 | 4.31e-01 | 87.3% | 84.6% |
| 4973737 | 2006.1.1.7 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › S6PP | 0.56 | 45.0 | 3.13e-01 | 93.7% | 25.4% |
| 3984327 | 241.1.1.4 ↗ | a+b two layers › Type III secretory system chaperone-like › Type III secretory system chaperone › Type III secretory system chaperone › Chaperone_III | 0.56 | 46.0 | 3.96e-01 | 100.0% | 59.1% |
| 6630 | 241.1.1.4 ↗ | a+b two layers › Type III secretory system chaperone-like › Type III secretory system chaperone › Type III secretory system chaperone › Chaperone_III | 0.55 | 45.0 | 3.93e-01 | 100.0% | 56.9% |
| 5036173 | 2003.1.5.66 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 | 0.55 | 48.0 | 3.35e-01 | 98.4% | 89.0% |
| 4943581 | 328.4.1.0 ↗ | a+b two layers › IF3-like › YhbY-like › YhbY-like | 0.54 | 47.0 | 4.40e-01 | 100.0% | 87.5% |
| 5063572 | 328.3.1.0 ↗ | a+b two layers › IF3-like › Translation initiation factor IF3, C-terminal domain › Translation initiation factor IF3, C-terminal domain | 0.54 | 46.0 | 4.47e-01 | 96.8% | 97.1% |
| 4933974 | 328.9.1.0 ↗ | a+b two layers › IF3-like › SepF C-terminal domain › SepF C-terminal domain | 0.54 | 44.0 | 4.46e-01 | 96.8% | 100.0% |
| 4950695 | 328.1.1.0 ↗ | a+b two layers › IF3-like › AlbA-like › AlbA-like | 0.54 | 44.0 | 4.27e-01 | 96.8% | 94.7% |
| 5076758 | 328.9.1.0 ↗ | a+b two layers › IF3-like › SepF C-terminal domain › SepF C-terminal domain | 0.53 | 44.0 | 4.22e-01 | 95.2% | 92.0% |
| 3383213 | 5.1.3.67 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › FBA_1 | 0.51 | 42.0 | 2.69e-01 | 90.5% | 28.9% |
D2
medium
residues 64-245
Domain cluster:
rep: protein_kinase_1__YP_006607886__Apocheima_cinerarium_nucleopolyhedrovirus__307461__D112-283
Pfam (2)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00069.32 best | Pkinase | 56.0 | 5.90e-15 | 86.3% | 59.9% |
| PF07714.24 | PK_Tyr_Ser-Thr | 37.1 | 3.10e-09 | 86.3% | 58.9% |
D3
medium
residues 248-347