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putative_3D_RNA-dependent_RNA_polymerase
Euk-Virtremovirus_B1
putative_3D_RNA-dependent_RNA_polymerase__YP_009553719__tremovirus_B1__2058161
Identity
- Accession:
- YP_009553719 ↗
- Protein ID:
- putative_3D_RNA-dependent_RNA_polymerase
- Kingdom:
- euk
Quality
91.9
mean pLDDT
Taxonomy
Orthornavirae›
Pisuviricota›
Pisoniviricetes›
Picornavirales›
Picornaviridae›
Tremovirus›
tremovirus_B1
TaxID: 2058161
Cluster
View cluster (450 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 405-481
Domain cluster:
representative
CATH (30)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1ra6A03 | 1.20.960.20 | Mainly Alpha › Up-down Bundle › Mitochondrial Import Receptor Subunit Tom20; Chain A › | 0.85 | 77.0 | 7.37e-01 | 100.0% | 86.2% |
| 3nkyA03 | 1.20.960.20 | Mainly Alpha › Up-down Bundle › Mitochondrial Import Receptor Subunit Tom20; Chain A › | 0.80 | 61.0 | 6.29e-01 | 92.2% | 86.3% |
| 1khvA05 | 1.20.960.20 | Mainly Alpha › Up-down Bundle › Mitochondrial Import Receptor Subunit Tom20; Chain A › | 0.77 | 70.0 | 6.48e-01 | 100.0% | 94.8% |
| 2ckwA04 | 1.20.960.20 | Mainly Alpha › Up-down Bundle › Mitochondrial Import Receptor Subunit Tom20; Chain A › | 0.75 | 67.0 | 6.06e-01 | 100.0% | 86.0% |
| 3h5xA04 | 1.20.960.20 | Mainly Alpha › Up-down Bundle › Mitochondrial Import Receptor Subunit Tom20; Chain A › | 0.64 | 56.0 | 5.23e-01 | 98.7% | 89.5% |
| 4jxtA00 | 1.25.40.90 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.63 | 48.0 | 4.15e-01 | 84.4% | 61.5% |
| 4qnsA00 | 1.20.920.10 | Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like | 0.63 | 43.0 | 3.89e-01 | 70.1% | 74.5% |
| 1ks8A00 | 1.50.10.10 | Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › | 0.62 | 49.0 | 3.12e-01 | 88.3% | 37.9% |
| 5ab0C04 | 1.25.50.20 | Mainly Alpha › Alpha Horseshoe › Zincin-like fold › | 0.62 | 51.0 | 3.38e-01 | 90.9% | 59.8% |
| 2bnlC00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.60 | 48.0 | 4.05e-01 | 89.6% | 71.6% |
| 4gytA00 | 1.20.120.740 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YgfB uncharacterised protein family PF03695 | 0.60 | 45.0 | 3.45e-01 | 80.5% | 84.2% |
| 2rekA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.59 | 50.0 | 3.91e-01 | 96.1% | 77.9% |
| 1xqrA00 | 1.25.10.10 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant | 0.59 | 45.0 | 3.18e-01 | 84.4% | 47.2% |
| 2f07B00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.59 | 51.0 | 3.87e-01 | 100.0% | 56.1% |
| 2mabA00 | 1.10.10.1350 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Spidroin domain, C-terminal domain | 0.59 | 45.0 | 4.06e-01 | 83.1% | 84.4% |
| 3beyD00 | 1.20.1290.10 | Mainly Alpha › Up-down Bundle › AhpD-like › AhpD-like | 0.58 | 45.0 | 4.33e-01 | 90.9% | 72.3% |
| 7miqA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.57 | 44.0 | 4.04e-01 | 87.0% | 92.7% |
| 3lwjA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.57 | 47.0 | 3.71e-01 | 100.0% | 78.8% |
| 1elkA00 | 1.25.40.90 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.56 | 42.0 | 3.47e-01 | 83.1% | 47.1% |
| 2fd5A02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.56 | 44.0 | 3.86e-01 | 92.2% | 78.8% |
| 4q5nA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.56 | 43.0 | 3.86e-01 | 85.7% | 96.4% |
| 3cqyB01 | 3.30.420.40 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain | 0.55 | 43.0 | 3.39e-01 | 88.3% | 46.2% |
| 2lvfA00 | 1.10.110.10 | Mainly Alpha › Orthogonal Bundle › Hydrophobic Seed Protein › Plant lipid-transfer and hydrophobic proteins | 0.55 | 41.0 | 3.72e-01 | 83.1% | 78.9% |
| 3v7dD01 | 1.20.1280.50 | Mainly Alpha › Up-down Bundle › Monooxygenase › | 0.55 | 38.0 | 3.58e-01 | 84.4% | 57.0% |
| 1b1uA00 | 1.10.110.10 | Mainly Alpha › Orthogonal Bundle › Hydrophobic Seed Protein › Plant lipid-transfer and hydrophobic proteins | 0.55 | 43.0 | 3.78e-01 | 84.4% | 88.0% |
| 3g2bA00 | 1.10.10.1150 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Coenzyme PQQ synthesis protein D (PqqD) | 0.54 | 36.0 | 3.45e-01 | 70.1% | 58.9% |
| 1iygA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.54 | 48.0 | 4.02e-01 | 100.0% | 81.2% |
| 4o6yB00 | 1.20.120.1770 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.53 | 46.0 | 3.43e-01 | 98.7% | 94.8% |
| 5d18A00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.53 | 43.0 | 3.39e-01 | 98.7% | 78.7% |
| 4he8D00 | 1.20.120.1200 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › NADH-ubiquinone/plastoquinone oxidoreductase chain 6, subunit NuoJ | 0.52 | 37.0 | 3.06e-01 | 75.3% | 43.1% |
ECOD (24)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2541767 | 4967.1.1.0 ↗ | alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases | 0.87 | 80.0 | 7.40e-01 | 100.0% | 79.4% |
| 1519288 | 4967.1.1.0 ↗ | alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases | 0.84 | 78.0 | 7.16e-01 | 100.0% | 83.5% |
| 3092371 | 4967.1.1.0 ↗ | alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases | 0.82 | 75.0 | 6.80e-01 | 100.0% | 81.4% |
| 158313 | 4967.1.1.2 ↗ | alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › RdRP_1 | 0.76 | 68.0 | 5.74e-01 | 100.0% | 72.4% |
| 5020681 | 3352.1.1.0 ↗ | alpha bundles › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain | 0.71 | 58.0 | 3.64e-01 | 92.2% | 37.3% |
| 3572779 | 3855.1.1.1 ↗ | alpha arrays › Serum amyloid A-1 protein › Serum amyloid A-1 protein › Serum amyloid A-1 protein › SAA | 0.71 | 58.0 | 5.17e-01 | 89.6% | 82.7% |
| 3673910 | 109.4.1.64 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › GET4 | 0.66 | 55.0 | 4.21e-01 | 93.5% | 73.0% |
| 3595737 | 109.4.1.218 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › SNAP | 0.65 | 50.0 | 4.02e-01 | 81.8% | 48.0% |
| 3878750 | 109.4.1.153 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › FANCF | 0.65 | 49.0 | 3.81e-01 | 83.1% | 51.9% |
| 3289317 | 191.1.1.41 ↗ | alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › EthR_C | 0.64 | 57.0 | 4.57e-01 | 98.7% | 73.3% |
| 3971032 | 1051.1.1.1 ↗ | alpha superhelices › Putative 3-oxoacyl-(acyl-carrier-protein) synthase N-terminal domain › Putative 3-oxoacyl-(acyl-carrier-protein) synthase N-terminal domain › Putative 3-oxoacyl-(acyl-carrier-protein) synthase N-terminal domain › HOASN | 0.63 | 50.0 | 4.78e-01 | 88.3% | 91.1% |
| 5044977 | 1076.1.1.0 ↗ | alpha bundles › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related | 0.63 | 43.0 | 2.91e-01 | 71.4% | 59.3% |
| 1806481 | 1051.1.1.1 ↗ | alpha superhelices › Putative 3-oxoacyl-(acyl-carrier-protein) synthase N-terminal domain › Putative 3-oxoacyl-(acyl-carrier-protein) synthase N-terminal domain › Putative 3-oxoacyl-(acyl-carrier-protein) synthase N-terminal domain › HOASN | 0.62 | 47.0 | 4.50e-01 | 84.4% | 84.0% |
| 4449988 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.62 | 51.0 | 4.04e-01 | 90.9% | 45.6% |
| 4928237 | 131.1.1.0 ↗ | alpha complex topology › PDEase-like › HD-domain/PDEase-like › HD-domain/PDEase-like | 0.60 | 51.0 | 3.99e-01 | 96.1% | 68.8% |
| 3596158 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.59 | 48.0 | 3.98e-01 | 92.2% | 91.3% |
| 3784830 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.58 | 46.0 | 3.46e-01 | 87.0% | 47.2% |
| 5016502 | 191.1.1.14 ↗ | alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › TetR_C_10 | 0.56 | 48.0 | 4.05e-01 | 97.4% | 75.6% |
| 4502412 | 109.2.1.7 ↗ | alpha superhelices › Repetitive alpha hairpins › alpha/alpha toroid › alpha/alpha toroid › Terpene_synth | 0.55 | 46.0 | 3.46e-01 | 98.7% | 81.8% |
| 3691250 | 109.4.1.356 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fungal_trans | 0.55 | 46.0 | 2.91e-01 | 97.4% | 53.7% |
| 3799978 | 7015.1.1.0 ↗ | alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain | 0.54 | 37.0 | 3.08e-01 | 100.0% | 39.3% |
| 4946473 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.54 | 39.0 | 3.80e-01 | 79.2% | 97.8% |
| 4928813 | 3843.1.1.0 ↗ | alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K | 0.54 | 38.0 | 3.93e-01 | 87.0% | 77.3% |
| 4972573 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.53 | 46.0 | 3.01e-01 | 100.0% | 81.3% |
D2
medium
residues 1-70_163-183
Domain cluster:
representative
ECOD (3)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5367 | 304.48.1.8 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RdRP_1 | 0.83 | 76.0 | 4.90e-01 | 98.9% | 48.1% |
| None | — | 0.82 | 75.0 | 4.90e-01 | 98.9% | 48.4% | |
| 2541763 | 304.48.1.8 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RdRP_1 | 0.79 | 73.0 | 4.70e-01 | 98.9% | 46.9% |
D3
medium
residues 71-162_184-210_248-303
Domain cluster:
rep: RNA-dependent_RNA-polymerase_-RdRp-__YP_004429254__Grapevine_Bulgarian_latent_virus__748667__D66-229_264-320
ECOD (23)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5367 | 304.48.1.8 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RdRP_1 | 0.90 | 87.0 | 6.50e-01 | 100.0% | 60.6% |
| 2541763 | 304.48.1.8 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RdRP_1 | 0.85 | 82.0 | 6.17e-01 | 100.0% | 61.3% |
| 1173784 | 304.48.1.8 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RdRP_1 | 0.85 | 82.0 | 6.17e-01 | 100.0% | 59.9% |
| None | — | 0.83 | 81.0 | 6.09e-01 | 100.0% | 59.8% | |
| 1875037 | 304.48.1.8 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RdRP_1 | 0.82 | 78.0 | 5.84e-01 | 100.0% | 58.7% |
| 5364 | 304.48.1.8 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RdRP_1 | 0.81 | 77.0 | 5.78e-01 | 100.0% | 57.5% |
| 3883010 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.73 | 55.0 | 4.52e-01 | 77.1% | 65.0% |
| 3928801 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.72 | 67.0 | 5.26e-01 | 100.0% | 64.6% |
| 3258406 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.71 | 66.0 | 4.52e-01 | 100.0% | 41.8% |
| 3273928 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.70 | 66.0 | 4.51e-01 | 100.0% | 41.8% |
| 3920615 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.70 | 66.0 | 4.77e-01 | 100.0% | 51.2% |
| 3884315 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.70 | 65.0 | 4.37e-01 | 100.0% | 37.0% |
| 3784946 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.70 | 65.0 | 4.86e-01 | 100.0% | 56.1% |
| None | — | 0.70 | 65.0 | 4.34e-01 | 100.0% | 36.3% | |
| 3877925 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.70 | 64.0 | 4.94e-01 | 100.0% | 60.5% |
| 3772920 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.70 | 65.0 | 5.36e-01 | 100.0% | 77.3% |
| 3875601 | 141.1.1.0 ↗ | alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases | 0.69 | 65.0 | 3.98e-01 | 100.0% | 24.0% |
| 3789227 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.69 | 64.0 | 5.23e-01 | 100.0% | 76.5% |
| 3753267 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.69 | 64.0 | 4.72e-01 | 100.0% | 53.3% |
| 3753579 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.69 | 64.0 | 4.46e-01 | 100.0% | 43.4% |
| 3939319 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.69 | 63.0 | 4.84e-01 | 100.0% | 62.5% |
| 3792091 | 304.48.1.25 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RRM_4 | 0.65 | 59.0 | 4.68e-01 | 98.3% | 59.4% |
| 3615272 | 304.48.1.25 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RRM_4 | 0.64 | 59.0 | 4.53e-01 | 99.4% | 59.7% |
D4
medium
residues 211-247_304-404
Domain cluster:
rep: KR816341.1__AKQ06880.1__X__00021__D162-195_238-325
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00680.26 best | RdRP_1 | 45.7 | 5.50e-12 | 73.2% | 21.3% |