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putative_DNA_polymerase_epsilon_subunit
Euk-VirAureococcus_anophagefferens_virus
putative_DNA_polymerase_epsilon_subunit__YP_009052389__Aureococcus_anophagefferens_virus__1474867
Identity
- Accession:
- YP_009052389 ↗
- Protein ID:
- putative_DNA_polymerase_epsilon_subunit
- Kingdom:
- euk
Quality
89.3
mean pLDDT
Taxonomy
Bamfordvirae›
Nucleocytoviricota›
Megaviricetes›
Imitervirales›
Schizomimiviridae›
Kratosvirus›
Aureococcus_anophagefferens_virus
TaxID: 1474867
Cluster
View cluster (66 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 2-144
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00929.32 best | RNase_T | 31.7 | 3.00e-07 | 97.2% | 68.3% |
CATH (7)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2p1jA01 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.90 | 69.0 | 7.08e-01 | 100.0% | 81.2% |
| 2qxfA01 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.86 | 74.0 | 6.52e-01 | 100.0% | 65.6% |
| 2f96A00 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.79 | 69.0 | 6.08e-01 | 100.0% | 65.7% |
| 2a1rB01 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.74 | 69.0 | 5.39e-01 | 100.0% | 91.8% |
| 6ro0F00 | 2.40.50.110 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › | 0.70 | 28.0 | 3.40e-01 | 71.3% | 53.1% |
| 4ep4A00 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.63 | 44.0 | 4.19e-01 | 100.0% | 62.0% |
| 1kcfB00 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.53 | 41.0 | 3.53e-01 | 100.0% | 51.3% |
ECOD (29)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4037317 | 2484.1.1.13 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_T | 0.92 | 70.0 | 6.07e-01 | 100.0% | 54.6% |
| 3945113 | 2484.1.1.13 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_T | 0.91 | 72.0 | 6.59e-01 | 100.0% | 65.0% |
| 5062283 | 2484.1.1.13 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_T | 0.90 | 73.0 | 6.29e-01 | 100.0% | 57.8% |
| 3587075 | 2484.1.1.13 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_T | 0.90 | 68.0 | 6.38e-01 | 100.0% | 65.3% |
| 3941572 | 2484.1.1.13 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_T | 0.86 | 73.0 | 5.39e-01 | 100.0% | 38.3% |
| 1501363 | 4.1.1.0 ↗ | beta barrels › SH3 › SH3 › SH3 | 0.86 | 73.0 | 4.90e-01 | 100.0% | 27.0% |
| 4044377 | 4.1.1.0 ↗ | beta barrels › SH3 › SH3 › SH3 | 0.86 | 73.0 | 4.88e-01 | 100.0% | 26.8% |
| 4381276 | 2484.1.1.13 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_T | 0.80 | 70.0 | 5.92e-01 | 100.0% | 58.9% |
| 4044396 | 2484.1.1.13 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_T | 0.80 | 70.0 | 6.12e-01 | 100.0% | 64.4% |
| 4299237 | 2484.1.1.13 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_T | 0.78 | 70.0 | 6.00e-01 | 100.0% | 63.3% |
| 3786380 | 2484.1.1.45 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › CAF1 | 0.76 | 71.0 | 5.51e-01 | 100.0% | 55.5% |
| 4571749 | 2484.1.1.25 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RuvC | 0.64 | 44.0 | 4.21e-01 | 100.0% | 60.6% |
| 3935094 | 2484.5.1.3 ↗ | mixed a+b and a/b › Ribonuclease H-like › RNaseH-like domain in reverse transcriptase › RNaseH-like domain in reverse transcriptase › RT_RNaseH_2 | 0.64 | 41.0 | 4.53e-01 | 100.0% | 80.0% |
| 3927497 | 2484.5.1.3 ↗ | mixed a+b and a/b › Ribonuclease H-like › RNaseH-like domain in reverse transcriptase › RNaseH-like domain in reverse transcriptase › RT_RNaseH_2 | 0.63 | 31.0 | 4.22e-01 | 74.1% | 88.7% |
| 3926560 | 2484.1.1.212 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RT_RNaseH | 0.61 | 43.0 | 4.49e-01 | 100.0% | 77.0% |
| 5024208 | 2484.1.1.23 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Hydantoinase_A | 0.60 | 40.0 | 4.12e-01 | 100.0% | 71.1% |
| 3933422 | 2484.5.1.2 ↗ | mixed a+b and a/b › Ribonuclease H-like › RNaseH-like domain in reverse transcriptase › RNaseH-like domain in reverse transcriptase › RT_RNaseH | 0.59 | 43.0 | 4.47e-01 | 100.0% | 80.8% |
| 3933233 | 2484.5.1.2 ↗ | mixed a+b and a/b › Ribonuclease H-like › RNaseH-like domain in reverse transcriptase › RNaseH-like domain in reverse transcriptase › RT_RNaseH | 0.58 | 42.0 | 4.38e-01 | 100.0% | 80.8% |
| 3934889 | 2484.5.1.2 ↗ | mixed a+b and a/b › Ribonuclease H-like › RNaseH-like domain in reverse transcriptase › RNaseH-like domain in reverse transcriptase › RT_RNaseH | 0.58 | 42.0 | 4.48e-01 | 100.0% | 84.8% |
| 3932481 | 2484.5.1.2 ↗ | mixed a+b and a/b › Ribonuclease H-like › RNaseH-like domain in reverse transcriptase › RNaseH-like domain in reverse transcriptase › RT_RNaseH | 0.58 | 42.0 | 4.40e-01 | 100.0% | 81.5% |
| 3927453 | 2484.5.1.2 ↗ | mixed a+b and a/b › Ribonuclease H-like › RNaseH-like domain in reverse transcriptase › RNaseH-like domain in reverse transcriptase › RT_RNaseH | 0.58 | 41.0 | 4.20e-01 | 100.0% | 75.6% |
| 3940510 | 2484.5.1.2 ↗ | mixed a+b and a/b › Ribonuclease H-like › RNaseH-like domain in reverse transcriptase › RNaseH-like domain in reverse transcriptase › RT_RNaseH | 0.57 | 30.0 | 3.98e-01 | 75.5% | 92.5% |
| 3924494 | 2484.5.1.2 ↗ | mixed a+b and a/b › Ribonuclease H-like › RNaseH-like domain in reverse transcriptase › RNaseH-like domain in reverse transcriptase › RT_RNaseH | 0.57 | 41.0 | 4.48e-01 | 100.0% | 91.3% |
| 11195 | 2484.1.1.56 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDR | 0.57 | 30.0 | 3.76e-01 | 77.6% | 81.5% |
| 3940715 | 2484.5.1.2 ↗ | mixed a+b and a/b › Ribonuclease H-like › RNaseH-like domain in reverse transcriptase › RNaseH-like domain in reverse transcriptase › RT_RNaseH | 0.57 | 41.0 | 4.20e-01 | 100.0% | 77.8% |
| 3622016 | 2484.5.1.6 ↗ | mixed a+b and a/b › Ribonuclease H-like › RNaseH-like domain in reverse transcriptase › RNaseH-like domain in reverse transcriptase › Peptidase_A17 | 0.56 | 31.0 | 3.55e-01 | 76.2% | 72.4% |
| 3507332 | 2484.5.1.2 ↗ | mixed a+b and a/b › Ribonuclease H-like › RNaseH-like domain in reverse transcriptase › RNaseH-like domain in reverse transcriptase › RT_RNaseH | 0.54 | 40.0 | 4.05e-01 | 100.0% | 77.9% |
| 3469667 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.53 | 41.0 | 2.96e-01 | 100.0% | 28.2% |
| 5062570 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.53 | 28.0 | 3.32e-01 | 76.9% | 72.4% |
D2
medium
residues 145-201
Domain cluster:
representative
CATH (14)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1y97A01 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.79 | 64.0 | 4.29e-01 | 93.0% | 25.0% |
| 6vddD01 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.78 | 65.0 | 4.48e-01 | 91.2% | 33.0% |
| 1d5aA02 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.74 | 61.0 | 4.09e-01 | 91.2% | 33.2% |
| 1noyB02 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.64 | 49.0 | 3.43e-01 | 91.2% | 53.5% |
| 5z5mA01 | 1.10.3330.10 | Mainly Alpha › Orthogonal Bundle › UraD-like › Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase | 0.62 | 46.0 | 3.41e-01 | 80.7% | 85.9% |
| 3lysA00 | 1.10.150.130 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Tyrosine recombinase, N-terminal domain | 0.59 | 41.0 | 3.40e-01 | 73.7% | 74.3% |
| 2ip6A00 | 1.20.1440.140 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.56 | 39.0 | 3.38e-01 | 71.9% | 59.8% |
| 3euhC02 | 1.10.10.2260 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › MukE-like family, C-terminal domain | 0.56 | 42.0 | 3.54e-01 | 86.0% | 64.8% |
| 1szhA01 | 1.10.150.360 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › | 0.55 | 42.0 | 4.01e-01 | 82.5% | 93.8% |
| 2ikbC00 | 1.20.141.10 | Mainly Alpha › Up-down Bundle › Chitosanase, subunit A; domain 1 › Chitosanase, subunit A, domain 1 | 0.54 | 43.0 | 3.25e-01 | 93.0% | 47.2% |
| 2bduA02 | 1.10.150.340 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Pyrimidine 5'-nucleotidase (UMPH-1), N-terminal domain | 0.54 | 43.0 | 3.98e-01 | 89.5% | 82.4% |
| 3hzsA00 | 1.10.3810.10 | Mainly Alpha › Orthogonal Bundle › Penicillin binding protein transpeptidase fold › Biosynthetic peptidoglycan transglycosylase-like | 0.54 | 42.0 | 2.86e-01 | 86.0% | 32.1% |
| 3rkgA02 | 1.20.58.340 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region | 0.53 | 43.0 | 3.15e-01 | 91.2% | 84.1% |
| 1e2tA01 | 6.10.140.1930 | Special › Helix non-globular › Helix Hairpins › | 0.50 | 38.0 | 3.56e-01 | 82.5% | 71.8% |
ECOD (19)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3707510 | 2484.1.1.13 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_T | 0.83 | 71.0 | 4.91e-01 | 93.0% | 30.0% |
| 3738098 | 2484.1.1.13 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_T | 0.82 | 70.0 | 4.57e-01 | 93.0% | 24.0% |
| 5025208 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.79 | 67.0 | 4.40e-01 | 93.0% | 30.4% |
| 4981192 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.78 | 66.0 | 4.24e-01 | 93.0% | 27.5% |
| 4188496 | 2484.1.1.20 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_A_exo1 | 0.76 | 63.0 | 4.33e-01 | 91.2% | 36.3% |
| 3244328 | 3340.1.1.0 ↗ | extended segments › Helical region in REST corepressor 1 › Helical region in REST corepressor 1 › Helical region in REST corepressor 1 | 0.64 | 45.0 | 4.47e-01 | 75.4% | 95.0% |
| 5054247 | 375.1.1.0 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related | 0.63 | 45.0 | 4.34e-01 | 86.0% | 67.7% |
| 4958553 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.63 | 48.0 | 3.37e-01 | 91.2% | 63.6% |
| 3220017 | 174.1.1.13 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › DUF2700 | 0.60 | 44.0 | 3.31e-01 | 82.5% | 31.0% |
| 4993069 | 632.12.1.1 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Vng1086c-like › Vng1086c-like › UPF0058 | 0.60 | 48.0 | 4.69e-01 | 91.2% | 81.0% |
| 3628125 | 632.15.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Staphylococcal complement inhibitor (SCIN) › Staphylococcal complement inhibitor (SCIN) | 0.59 | 49.0 | 4.51e-01 | 91.2% | 76.0% |
| 3955590 | 2006.1.1.44 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Hydrolase, Hydrolase_like | 0.56 | 44.0 | 3.01e-01 | 91.2% | 23.3% |
| 3210490 | 192.6.1.6 ↗ | alpha bundles › Long alpha-hairpin › Epsilon subunit of F1F0-ATP synthase C-terminal domain › Epsilon subunit of F1F0-ATP synthase C-terminal domain › VPS18_RING_C | 0.55 | 47.0 | 4.00e-01 | 91.2% | 71.1% |
| 5081878 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.55 | 44.0 | 2.73e-01 | 91.2% | 46.9% |
| 3461868 | 130.1.1.0 ↗ | alpha arrays › LEM/SAP HeH motif-like › LEM/SAP HeH motif › LEM/SAP HeH motif | 0.54 | 36.0 | 3.99e-01 | 80.7% | 100.0% |
| 5061636 | 150.1.1.205 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Trp_dioxygenase | 0.53 | 44.0 | 3.84e-01 | 91.2% | 94.0% |
| 5003681 | 2002.1.1.25 ↗ | a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › HMGL-like | 0.52 | 40.0 | 2.42e-01 | 84.2% | 28.3% |
| 3598690 | 108.1.1.0 ↗ | alpha arrays › EF-hand › EF-hand-related › EF-hand | 0.51 | 40.0 | 3.37e-01 | 86.0% | 51.6% |
| 5044961 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.51 | 39.0 | 3.87e-01 | 87.7% | 100.0% |