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putative_DNA_repair_protein

Euk-Vir

Acanthamoeba_polyphaga_moumouvirus

putative_DNA_repair_protein__YP_007354557__Acanthamoeba_polyphaga_moumouvirus__1269028

Identity

Accession:
YP_007354557 ↗
Protein ID:
putative_DNA_repair_protein
Kingdom:
euk

Quality

71.4 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 48-164_261-295
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00149.34 best Metallophos 44.2 4.50e-11 96.7% 58.8%
D2 medium residues 165-260
PDB
CATH (65)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4ltyA01 3.60.21.10 Alpha Beta › 4-Layer Sandwich › Purple Acid Phosphatase; chain A, domain 2 › Metallo-dependent phosphatases 0.80 74.0 5.18e-01 100.0% 47.0%
1g01A00 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.65 57.0 3.90e-01 100.0% 48.5%
6uqjA02 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.63 56.0 3.83e-01 100.0% 62.0%
6en3A01 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.62 55.0 3.83e-01 100.0% 47.7%
4hpnA02 3.20.20.120 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Enolase-like C-terminal domain 0.62 52.0 3.79e-01 92.7% 34.1%
3hpxA01 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.61 54.0 3.84e-01 97.9% 40.9%
1vc1A00 3.30.750.24 Alpha Beta › 2-Layer Sandwich › Transcription Regulator spoIIAA › STAS domain 0.61 55.0 5.30e-01 100.0% 90.9%
6p8vA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.61 53.0 4.21e-01 100.0% 97.2%
7whgG02 3.40.20.10 Alpha Beta › 3-Layer(aba) Sandwich › Severin › Severin 0.61 36.0 3.72e-01 85.4% 60.9%
4f1jA00 3.40.50.410 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › von Willebrand factor, type A domain 0.61 52.0 4.14e-01 94.8% 86.5%
4j7rA02 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.61 54.0 3.42e-01 100.0% 42.2%
2vy9A00 3.30.750.24 Alpha Beta › 2-Layer Sandwich › Transcription Regulator spoIIAA › STAS domain 0.61 54.0 5.09e-01 97.9% 86.8%
3e8xA00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.61 54.0 4.20e-01 100.0% 89.3%
2qjgA00 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.61 54.0 3.94e-01 100.0% 43.4%
7b7pA01 3.40.50.410 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › von Willebrand factor, type A domain 0.60 50.0 3.69e-01 91.7% 89.4%
5visB00 3.20.20.20 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Dihydropteroate synthase-like 0.60 53.0 3.87e-01 97.9% 53.2%
2ww8A03 3.40.50.410 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › von Willebrand factor, type A domain 0.60 51.0 3.59e-01 92.7% 88.8%
1gvfB00 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.60 52.0 3.83e-01 100.0% 39.3%
1m53A01 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.60 52.0 3.50e-01 100.0% 46.2%
1efzA00 3.20.20.105 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Queuine tRNA-ribosyltransferase-like 0.59 52.0 3.56e-01 100.0% 41.4%
6iumA01 3.90.226.10 Alpha Beta › Alpha-Beta Complex › 2-enoyl-CoA Hydratase; Chain A, domain 1 › 2-enoyl-CoA Hydratase; Chain A, domain 1 0.59 51.0 3.70e-01 95.8% 71.6%
3gkfA00 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.59 52.0 3.80e-01 100.0% 39.5%
2ihtA03 3.40.50.970 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains 0.59 50.0 3.91e-01 95.8% 77.1%
3hdcA01 3.40.30.10 Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin 0.58 39.0 3.62e-01 81.2% 51.6%
3s5nA00 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.58 52.0 3.70e-01 100.0% 37.3%
3wy1A01 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.58 51.0 3.42e-01 100.0% 39.4%
4xs5B00 3.30.750.24 Alpha Beta › 2-Layer Sandwich › Transcription Regulator spoIIAA › STAS domain 0.58 50.0 4.80e-01 99.0% 84.2%
3gkbA00 3.90.226.10 Alpha Beta › Alpha-Beta Complex › 2-enoyl-CoA Hydratase; Chain A, domain 1 › 2-enoyl-CoA Hydratase; Chain A, domain 1 0.57 51.0 3.74e-01 100.0% 67.2%
3l3sA01 3.90.226.10 Alpha Beta › Alpha-Beta Complex › 2-enoyl-CoA Hydratase; Chain A, domain 1 › 2-enoyl-CoA Hydratase; Chain A, domain 1 0.57 51.0 4.10e-01 100.0% 90.3%
2bgwB01 3.40.50.10130 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.57 45.0 4.13e-01 86.5% 80.9%
1zmbA01 3.40.50.1110 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › SGNH hydrolase 0.57 49.0 3.76e-01 100.0% 74.1%
3g64A01 3.90.226.10 Alpha Beta › Alpha-Beta Complex › 2-enoyl-CoA Hydratase; Chain A, domain 1 › 2-enoyl-CoA Hydratase; Chain A, domain 1 0.56 50.0 3.90e-01 100.0% 84.7%
2a35A00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.56 49.0 3.86e-01 97.9% 90.9%
6j0pA01 3.90.226.10 Alpha Beta › Alpha-Beta Complex › 2-enoyl-CoA Hydratase; Chain A, domain 1 › 2-enoyl-CoA Hydratase; Chain A, domain 1 0.56 49.0 3.70e-01 99.0% 69.3%
2ex2A02 3.50.80.20 Alpha Beta › 3-Layer(bba) Sandwich › D-tyrosyl-trna(Tyr) Deacylase; Chain: A; › D-Ala-D-Ala carboxypeptidase C, peptidase S13 0.56 44.0 4.35e-01 85.4% 86.4%
3e15A00 3.40.50.1360 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.55 44.0 3.24e-01 89.6% 35.7%
3zo9A01 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.55 48.0 3.26e-01 100.0% 37.1%
2wq7A01 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.55 41.0 3.65e-01 78.1% 60.6%
4x7rA01 3.40.50.2000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; 0.55 49.0 3.89e-01 100.0% 85.3%
3ha9A00 3.40.30.10 Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin 0.55 42.0 3.52e-01 80.2% 52.2%
3tosA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.55 46.0 3.45e-01 93.8% 74.1%
3odhA00 3.40.91.20 Alpha Beta › 3-Layer(aba) Sandwich › Restriction Endonuclease › 0.55 44.0 3.57e-01 88.5% 55.2%
6ebqA00 3.40.50.360 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Flavodoxin domain 0.55 45.0 4.04e-01 90.6% 81.9%
4rcnB03 3.90.226.10 Alpha Beta › Alpha-Beta Complex › 2-enoyl-CoA Hydratase; Chain A, domain 1 › 2-enoyl-CoA Hydratase; Chain A, domain 1 0.55 48.0 3.59e-01 100.0% 78.7%
3fdxA00 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.54 41.0 3.74e-01 81.2% 59.8%
6f2xA01 3.40.50.1000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like 0.54 46.0 3.96e-01 93.8% 90.1%
3ssmC02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.54 45.0 3.53e-01 93.8% 75.8%
5ailA00 3.40.220.10 Alpha Beta › 3-Layer(aba) Sandwich › Leucine Aminopeptidase, subunit E; domain 1 › Leucine Aminopeptidase, subunit E, domain 1 0.53 45.0 3.73e-01 95.8% 78.3%
3m1lA02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.53 46.0 3.68e-01 100.0% 72.3%
2yx1A02 3.30.300.110 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › Met-10+ protein-like domains 0.53 32.0 3.55e-01 79.2% 76.6%
4ycaB01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.52 43.0 3.68e-01 90.6% 69.0%
3bmxA02 3.40.50.1700 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycoside hydrolase family 3 C-terminal domain 0.52 45.0 3.51e-01 97.9% 81.2%
3bdiA00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.52 45.0 3.59e-01 99.0% 79.2%
5d84A01 3.40.50.1100 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.51 40.0 3.36e-01 87.5% 50.8%
3oqpA00 3.40.50.850 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Isochorismatase-like 0.51 38.0 3.05e-01 80.2% 42.0%
1xmxA02 3.40.1350.10 Alpha Beta › 3-Layer(aba) Sandwich › Trna Endonuclease; Chain: A, domain 1 › 0.51 44.0 3.89e-01 97.9% 82.6%
4kxvA02 3.40.50.970 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains 0.51 43.0 3.55e-01 97.9% 77.3%
1pg4A01 3.40.50.12780 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › ANL, N-terminal domain 0.51 44.0 2.83e-01 100.0% 61.4%
1adeA01 3.40.440.10 Alpha Beta › 3-Layer(aba) Sandwich › Adenylosuccinate Synthetase; Chain A, domain 1 › Adenylosuccinate Synthetase, subunit A, domain 1 0.51 37.0 3.23e-01 80.2% 86.7%
2bpoA04 3.40.50.80 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module 0.51 41.0 3.50e-01 89.6% 58.0%
1gp1A00 3.40.30.10 Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin 0.50 37.0 3.04e-01 78.1% 42.4%
3cynB00 3.40.30.10 Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin 0.50 38.0 3.20e-01 82.3% 47.4%
3graA00 3.40.50.880 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Class I glutamine amidotransferase (GATase) domain 0.50 40.0 3.27e-01 87.5% 82.2%
4zeoH02 3.40.50.10470 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Translation initiation factor eif-2b; domain 2 0.50 42.0 3.61e-01 94.8% 86.3%
1zzgA01 3.40.50.10490 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 0.50 38.0 2.94e-01 84.4% 56.5%
ECOD (59)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3288214 246.2.1.1 a+b four layers › Carbon-nitrogen hydrolase-like › Metallo-dependent phosphatases › Metallo-dependent phosphatases › Metallophos 0.79 74.0 5.19e-01 100.0% 44.8%
3958752 246.2.1.0 a+b four layers › Carbon-nitrogen hydrolase-like › Metallo-dependent phosphatases › Metallo-dependent phosphatases 0.76 71.0 5.61e-01 100.0% 53.5%
4981992 246.2.1.1 a+b four layers › Carbon-nitrogen hydrolase-like › Metallo-dependent phosphatases › Metallo-dependent phosphatases › Metallophos 0.76 70.0 4.97e-01 100.0% 36.9%
4165457 246.2.1.1 a+b four layers › Carbon-nitrogen hydrolase-like › Metallo-dependent phosphatases › Metallo-dependent phosphatases › Metallophos 0.75 70.0 4.88e-01 100.0% 46.0%
4956932 246.2.1.1 a+b four layers › Carbon-nitrogen hydrolase-like › Metallo-dependent phosphatases › Metallo-dependent phosphatases › Metallophos 0.75 67.0 4.87e-01 100.0% 36.9%
4977727 246.2.1.0 a+b four layers › Carbon-nitrogen hydrolase-like › Metallo-dependent phosphatases › Metallo-dependent phosphatases 0.69 63.0 4.56e-01 100.0% 38.8%
4995726 246.2.1.1 a+b four layers › Carbon-nitrogen hydrolase-like › Metallo-dependent phosphatases › Metallo-dependent phosphatases › Metallophos 0.68 59.0 4.26e-01 100.0% 35.3%
3219936 2002.1.1.0 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels 0.67 60.0 4.08e-01 100.0% 43.7%
3494443 247.1.1.0 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase 0.65 58.0 4.06e-01 100.0% 51.9%
4456929 2495.1.1.0 a/b three-layered sandwiches › Cell-division inhibitor MinC, N-terminal domain › Cell-division inhibitor MinC, N-terminal domain › Cell-division inhibitor MinC, N-terminal domain 0.64 57.0 5.75e-01 99.0% 97.9%
4529833 2495.1.1.2 a/b three-layered sandwiches › Cell-division inhibitor MinC, N-terminal domain › Cell-division inhibitor MinC, N-terminal domain › Cell-division inhibitor MinC, N-terminal domain › MinC_N_1 0.64 53.0 5.52e-01 89.6% 95.6%
4198344 2495.1.1.2 a/b three-layered sandwiches › Cell-division inhibitor MinC, N-terminal domain › Cell-division inhibitor MinC, N-terminal domain › Cell-division inhibitor MinC, N-terminal domain › MinC_N_1 0.63 56.0 5.28e-01 100.0% 81.7%
4521590 2002.1.1.60 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › AP_endonuc_2 0.63 55.0 3.99e-01 100.0% 58.6%
3887264 2011.2.1.11 a/b three-layered sandwiches › Phosphorylase/hydrolase-like › Peptidyl-tRNA hydrolase-like › Peptidyl-tRNA hydrolase-like › PAC1 0.63 47.0 3.53e-01 80.2% 70.6%
3838471 246.2.1.1 a+b four layers › Carbon-nitrogen hydrolase-like › Metallo-dependent phosphatases › Metallo-dependent phosphatases › Metallophos 0.62 57.0 4.18e-01 100.0% 42.4%
3500810 2008.1.1.68 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PND 0.62 48.0 4.47e-01 85.4% 65.0%
11464 2496.1.1.2 a/b three-layered sandwiches › SpoIIaa-like › SpoIIaa-like › SpoIIaa-like › STAS 0.61 55.0 5.30e-01 100.0% 90.9%
3353667 2484.1.1.67 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RVT_3 0.61 45.0 3.95e-01 78.1% 77.9%
3677978 7577.1.1.8 a/b three-layered sandwiches › PLP-dependent transferases › PLP-dependent transferases › PLP-dependent transferases › Beta_elim_lyase 0.61 55.0 3.88e-01 99.0% 46.2%
3930656 2006.1.6.1 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › VWA 0.61 52.0 4.03e-01 93.8% 82.3%
4634847 2002.1.1.60 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › AP_endonuc_2 0.61 53.0 3.89e-01 100.0% 64.8%
3824739 7579.1.1.18 a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Abhydrolase_2 0.61 55.0 4.02e-01 100.0% 76.2%
4997915 7512.1.1.32 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_trans_1_4 0.61 40.0 3.22e-01 79.2% 33.2%
94553 2002.1.1.8 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Cellulase 0.61 53.0 3.71e-01 100.0% 45.3%
3960577 2496.1.1.0 a/b three-layered sandwiches › SpoIIaa-like › SpoIIaa-like › SpoIIaa-like 0.61 54.0 5.15e-01 100.0% 87.8%
3929025 2006.1.6.1 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › VWA 0.61 52.0 3.97e-01 92.7% 75.8%
3928280 2002.1.1.220 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Menorin 0.61 55.0 4.03e-01 100.0% 62.0%
991597 2496.1.1.2 a/b three-layered sandwiches › SpoIIaa-like › SpoIIaa-like › SpoIIaa-like › STAS 0.60 54.0 5.11e-01 100.0% 88.6%
3439933 2002.1.1.30 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Glyco_hydro_18 0.60 54.0 3.93e-01 100.0% 54.3%
5074695 2006.1.6.1 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › VWA 0.60 51.0 3.70e-01 92.7% 77.0%
5075843 2496.1.1.2 a/b three-layered sandwiches › SpoIIaa-like › SpoIIaa-like › SpoIIaa-like › STAS 0.60 53.0 4.90e-01 100.0% 82.9%
2526040 2496.1.1.2 a/b three-layered sandwiches › SpoIIaa-like › SpoIIaa-like › SpoIIaa-like › STAS 0.59 52.0 4.92e-01 100.0% 85.6%
3837240 2005.1.1.3 a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › Usp 0.59 45.0 3.66e-01 80.2% 51.4%
3969700 2496.1.1.2 a/b three-layered sandwiches › SpoIIaa-like › SpoIIaa-like › SpoIIaa-like › STAS 0.59 52.0 5.02e-01 99.0% 90.0%
3471912 7570.1.1.0 a/b three-layered sandwiches › MurD-like peptide ligases, peptide-binding domain › MurD-like peptide ligases, peptide-binding domain › MurD-like peptide ligases, peptide-binding domain 0.59 51.0 4.21e-01 100.0% 65.9%
4046211 7570.1.1.1 a/b three-layered sandwiches › MurD-like peptide ligases, peptide-binding domain › MurD-like peptide ligases, peptide-binding domain › MurD-like peptide ligases, peptide-binding domain › Mur_ligase_C 0.59 52.0 4.43e-01 100.0% 69.4%
169543 2496.1.1.2 a/b three-layered sandwiches › SpoIIaa-like › SpoIIaa-like › SpoIIaa-like › STAS 0.58 51.0 4.92e-01 100.0% 88.5%
11463 2496.1.1.2 a/b three-layered sandwiches › SpoIIaa-like › SpoIIaa-like › SpoIIaa-like › STAS 0.58 52.0 4.91e-01 100.0% 86.1%
5078268 2004.1.1.76 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DUF87 0.58 49.0 3.54e-01 94.8% 56.9%
1498185 2496.1.1.2 a/b three-layered sandwiches › SpoIIaa-like › SpoIIaa-like › SpoIIaa-like › STAS 0.58 51.0 4.78e-01 100.0% 81.1%
4990096 7561.1.1.1 a/b three-layered sandwiches › Isochorismatase-like hydrolases › Isochorismatase-like hydrolases › Isochorismatase-like hydrolases › Isochorismatase 0.57 48.0 3.90e-01 92.7% 87.0%
5032511 2008.1.1.226 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › RE_EcoO109I 0.57 45.0 3.40e-01 84.4% 40.9%
3781316 2008.1.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.57 45.0 4.29e-01 87.5% 80.9%
3633643 2003.1.1.0 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains 0.56 50.0 3.31e-01 100.0% 77.1%
3402825 2486.1.1.1 a/b three-layered sandwiches › ClpP/crotonase › ClpP/crotonase › ClpP/crotonase › ECH_1 0.56 50.0 3.84e-01 100.0% 73.5%
4956819 2008.1.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.56 45.0 4.36e-01 87.5% 80.0%
3824329 2005.1.1.3 a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › Usp 0.56 46.0 3.83e-01 89.6% 98.8%
5030221 327.7.1.2 a+b two layers › Alpha-lytic protease prodomain-like › Cation efflux protein cytoplasmic domain-like › Cation efflux protein cytoplasmic domain-like › FKBP26_C 0.56 32.0 3.81e-01 87.5% 88.3%
3265703 7512.1.1.3 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glycos_transf_1 0.56 43.0 3.48e-01 82.3% 46.5%
2439579 2008.1.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.56 48.0 3.49e-01 100.0% 35.8%
5026379 2486.1.1.1 a/b three-layered sandwiches › ClpP/crotonase › ClpP/crotonase › ClpP/crotonase › ECH_1 0.55 49.0 3.64e-01 100.0% 68.8%
3246973 2003.1.1.80 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › FAS_pseudo-KR 0.55 43.0 4.03e-01 87.5% 92.0%
3304144 2005.1.1.0 a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains 0.54 45.0 3.80e-01 92.7% 95.9%
3945413 2008.1.1.16 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Mrr_cat 0.54 48.0 4.01e-01 100.0% 82.9%
5027141 7575.1.1.2 a/b three-layered sandwiches › Caspase-like › Caspase-like › Caspase-like › Peptidase_C25 0.54 46.0 3.53e-01 99.0% 74.3%
3461060 2005.1.1.0 a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains 0.54 44.0 3.70e-01 91.7% 99.4%
2792935 2007.1.1.11 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Class I glutamine amidotransferase-like › Peptidase_C26 0.52 43.0 3.27e-01 93.8% 84.7%
4998006 7512.1.1.30 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_4 0.52 47.0 3.86e-01 100.0% 84.0%
4941909 327.18.1.4 a+b two layers › Alpha-lytic protease prodomain-like › 40S ribosomal protein S7-A › 40S ribosomal protein S7-A › KH_1 0.52 30.0 3.02e-01 87.5% 53.0%
D3 medium residues 303-352
PDB
Domain cluster: representative
CATH (18)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
5ly3A01 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.69 58.0 3.95e-01 100.0% 72.4%
3dnfA03 3.40.1010.20 Alpha Beta › 3-Layer(aba) Sandwich › Cobalt-precorrin-4 Transmethylase; domain 1 › 4-hydroxy-3-methylbut-2-enyl diphosphate reductase, catalytic domain 0.69 60.0 4.85e-01 100.0% 75.8%
2q0xA01 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.69 59.0 3.69e-01 100.0% 43.2%
3klbA00 3.40.50.360 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Flavodoxin domain 0.66 54.0 3.96e-01 100.0% 37.0%
6jqlA02 3.40.309.10 Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 2 › Aldehyde Dehydrogenase; Chain A, domain 2 0.65 55.0 3.66e-01 100.0% 85.1%
3l4bC01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.65 54.0 4.27e-01 100.0% 80.3%
2mwmA00 3.40.50.360 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Flavodoxin domain 0.65 54.0 3.96e-01 100.0% 39.1%
4idsA02 3.40.309.10 Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 2 › Aldehyde Dehydrogenase; Chain A, domain 2 0.63 52.0 3.57e-01 100.0% 93.4%
8oqxA01 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.62 51.0 4.09e-01 100.0% 81.6%
2c83A02 3.40.50.11110 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Sialyltransferase, C-terminal GT-B Rossman nucleotide-binding domain 0.61 51.0 3.59e-01 100.0% 39.2%
6vapB01 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.60 48.0 3.22e-01 100.0% 90.9%
1npyA01 3.40.50.10860 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Leucine Dehydrogenase, chain A, domain 1 0.59 40.0 3.29e-01 74.0% 59.0%
4ao8A00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.57 44.0 3.00e-01 94.0% 52.6%
8ckpA01 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.56 41.0 2.73e-01 90.0% 31.2%
3r0vA00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.54 44.0 2.90e-01 100.0% 87.5%
3uh0A02 3.40.50.800 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Anticodon-binding domain 0.54 37.0 2.89e-01 74.0% 62.1%
3rm3A00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.53 42.0 2.85e-01 100.0% 87.4%
2w8nA02 3.40.309.10 Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 2 › Aldehyde Dehydrogenase; Chain A, domain 2 0.51 42.0 2.92e-01 100.0% 66.5%
ECOD (27)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3601953 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.75 61.0 4.79e-01 94.0% 73.6%
4145176 2484.6.1.1 mixed a+b and a/b › Ribonuclease H-like › Periplasmic domain of ExbD/TolR › Periplasmic domain of ExbD/TolR › ExbD 0.74 63.0 5.36e-01 100.0% 76.5%
5041886 7573.1.1.1 a/b three-layered sandwiches › PRTase-like › PRTase-like › PRTase-like › Pribosyltran 0.74 64.0 4.51e-01 100.0% 52.2%
3778336 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.73 59.0 5.28e-01 94.0% 85.3%
4141320 2495.1.1.2 a/b three-layered sandwiches › Cell-division inhibitor MinC, N-terminal domain › Cell-division inhibitor MinC, N-terminal domain › Cell-division inhibitor MinC, N-terminal domain › MinC_N_1 0.71 59.0 5.23e-01 100.0% 83.7%
4128565 2495.1.1.2 a/b three-layered sandwiches › Cell-division inhibitor MinC, N-terminal domain › Cell-division inhibitor MinC, N-terminal domain › Cell-division inhibitor MinC, N-terminal domain › MinC_N_1 0.70 58.0 4.97e-01 100.0% 74.4%
4664048 3979.1.1.0 a+b four layers › Mre11 nuclease C-terminal domain › Mre11 nuclease C-terminal domain › Mre11 nuclease C-terminal domain 0.70 59.0 5.80e-01 98.0% 89.1%
3668534 207.1.1.0 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats 0.69 61.0 4.44e-01 100.0% 45.0%
4937194 7573.1.1.0 a/b three-layered sandwiches › PRTase-like › PRTase-like › PRTase-like 0.68 58.0 3.94e-01 100.0% 50.5%
4557051 2495.1.1.2 a/b three-layered sandwiches › Cell-division inhibitor MinC, N-terminal domain › Cell-division inhibitor MinC, N-terminal domain › Cell-division inhibitor MinC, N-terminal domain › MinC_N_1 0.68 58.0 4.74e-01 100.0% 67.0%
4433265 2495.1.1.2 a/b three-layered sandwiches › Cell-division inhibitor MinC, N-terminal domain › Cell-division inhibitor MinC, N-terminal domain › Cell-division inhibitor MinC, N-terminal domain › MinC_N_1 0.67 57.0 5.00e-01 100.0% 82.5%
4165458 3979.1.1.0 a+b four layers › Mre11 nuclease C-terminal domain › Mre11 nuclease C-terminal domain › Mre11 nuclease C-terminal domain 0.67 56.0 5.27e-01 100.0% 86.2%
3081158 7579.1.1.102 a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Peptidase_S9, Hydrolase_4 0.66 53.0 3.46e-01 94.0% 35.4%
137906 2007.2.1.5 a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › Flavoproteins › Flavodoxin_4 0.66 54.0 3.96e-01 100.0% 37.0%
4361143 2495.1.1.2 a/b three-layered sandwiches › Cell-division inhibitor MinC, N-terminal domain › Cell-division inhibitor MinC, N-terminal domain › Cell-division inhibitor MinC, N-terminal domain › MinC_N_1 0.65 54.0 4.79e-01 100.0% 83.7%
2512614 2003.1.9.7 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › Activating enzymes of the ubiquitin-like proteins › McbB 0.64 54.0 3.64e-01 100.0% 34.6%
3089795 7579.1.1.6 a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Abhydrolase_1 0.64 49.0 3.12e-01 90.0% 29.8%
3266614 2007.2.5.1 a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › Rhodanese/Cell cycle control phosphatase › Rhodanese 0.63 53.0 3.93e-01 100.0% 48.6%
3704518 246.2.1.0 a+b four layers › Carbon-nitrogen hydrolase-like › Metallo-dependent phosphatases › Metallo-dependent phosphatases 0.63 53.0 3.51e-01 100.0% 25.9%
5035523 2003.1.10.0 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › PreATP-grasp domain 0.62 51.0 4.16e-01 98.0% 89.5%
3238036 7585.1.1.1 a/b three-layered sandwiches › Rossmann-like domains in Sec1/munc18-like proteins › Rossmann-like domains in Sec1/munc18-like proteins › Rossmann-like domains in Sec1/munc18-like proteins › Sec1 0.59 48.0 3.34e-01 100.0% 57.1%
5065810 2003.1.10.0 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › PreATP-grasp domain 0.59 48.0 3.92e-01 98.0% 88.6%
3959363 2003.4.1.1 a/b three-layered sandwiches › Rossmann-like › Tryptophan synthase beta subunit-like PLP-dependent enzymes › Tryptophan synthase beta subunit-like PLP-dependent enzymes › PALP 0.58 44.0 3.40e-01 90.0% 39.2%
3941456 2007.1.3.31 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › MlrA_C 0.58 46.0 4.13e-01 100.0% 92.5%
3350254 7579.1.1.42 a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Hydrolase_4 0.56 41.0 2.74e-01 90.0% 37.2%
3966897 7579.1.1.44 a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Abhydrolase_6 0.55 41.0 2.57e-01 86.0% 42.1%
3585181 7579.1.1.42 a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Hydrolase_4 0.53 42.0 2.81e-01 100.0% 81.9%
D4 medium residues 430-593
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF13476.13 best AAA_23 56.8 7.10e-15 96.3% 73.1%
D5 medium residues 728-878_1018-1111
PDB
D6 medium residues 1112-1172
PDB
Domain cluster: representative