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putative_DNA_topoisomerase_IA

Euk-Vir

Aureococcus_anophagefferens_virus

putative_DNA_topoisomerase_IA__YP_009052166__Aureococcus_anophagefferens_virus__1474867

Identity

Accession:
YP_009052166 ↗
Protein ID:
putative_DNA_topoisomerase_IA
Kingdom:
euk

Quality

71.1 mean pLDDT

Taxonomy

Bamfordvirae› Nucleocytoviricota› Megaviricetes› Imitervirales› Schizomimiviridae› Kratosvirus› Aureococcus_anophagefferens_virus

TaxID: 1474867

Cluster

View cluster (9 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 671-713
PDB
D2 medium residues 3-124
PDB
Domain cluster: rep: IMGVR_UViG_3300014887_000003-3300014887-Ga0180302_1000002739__D2-143
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF01751.29 best Toprim 65.6 5.20e-18 87.7% 99.0%
CATH (49)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
5uj1A01 3.40.50.140 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.91 88.0 8.19e-01 100.0% 95.2%
2gaiA01 3.40.50.140 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.88 83.0 8.16e-01 100.0% 95.3%
4cgyA01 3.40.50.140 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.84 80.0 6.92e-01 100.0% 91.5%
1i7dA01 3.40.50.140 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.83 78.0 7.11e-01 100.0% 98.7%
5gvcB01 3.40.50.140 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.81 77.0 6.85e-01 100.0% 98.2%
1gkuB05 3.40.50.140 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.74 69.0 6.99e-01 100.0% 97.5%
6tg6A01 3.40.1360.10 Alpha Beta › 3-Layer(aba) Sandwich › Dna Topoisomerase Vi A Subunit; Chain: A, domain 2 › 0.72 58.0 6.28e-01 95.9% 100.0%
1q57G02 3.40.1360.10 Alpha Beta › 3-Layer(aba) Sandwich › Dna Topoisomerase Vi A Subunit; Chain: A, domain 2 › 0.71 61.0 6.03e-01 100.0% 87.3%
5gujA02 3.40.1360.10 Alpha Beta › 3-Layer(aba) Sandwich › Dna Topoisomerase Vi A Subunit; Chain: A, domain 2 › 0.71 58.0 5.84e-01 99.2% 84.8%
2au3A03 3.40.1360.10 Alpha Beta › 3-Layer(aba) Sandwich › Dna Topoisomerase Vi A Subunit; Chain: A, domain 2 › 0.70 57.0 5.74e-01 99.2% 84.7%
5vazA02 3.40.1360.10 Alpha Beta › 3-Layer(aba) Sandwich › Dna Topoisomerase Vi A Subunit; Chain: A, domain 2 › 0.68 58.0 5.69e-01 100.0% 85.2%
2xkbL00 3.40.50.1440 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Tubulin/FtsZ, GTPase domain 0.62 55.0 3.93e-01 99.2% 88.1%
3u48A02 3.40.50.1700 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycoside hydrolase family 3 C-terminal domain 0.61 54.0 4.16e-01 96.7% 65.8%
5z87B02 3.40.50.1700 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycoside hydrolase family 3 C-terminal domain 0.59 52.0 4.24e-01 97.5% 78.1%
3stuB00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.58 52.0 4.06e-01 99.2% 98.1%
4xrpA02 3.40.50.1000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like 0.58 43.0 4.29e-01 98.4% 74.4%
4lgvA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.57 51.0 4.43e-01 98.4% 97.9%
2vd3A02 3.40.190.10 Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II 0.57 31.0 3.47e-01 91.8% 67.0%
3ruiA00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.57 52.0 3.77e-01 99.2% 68.0%
6vlxA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.57 51.0 4.06e-01 100.0% 89.3%
4dcuA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.56 50.0 4.84e-01 97.5% 90.7%
1r1dA00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.56 50.0 4.01e-01 97.5% 94.6%
4rz2B00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.56 50.0 3.91e-01 96.7% 93.4%
3fnrA02 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.56 48.0 3.61e-01 94.3% 93.1%
1t0iA00 3.40.50.360 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Flavodoxin domain 0.56 48.0 4.23e-01 95.9% 96.2%
2v0nA02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.55 48.0 4.51e-01 97.5% 78.1%
2jjmA01 3.40.50.2000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; 0.55 50.0 4.38e-01 99.2% 98.3%
3abzA02 3.40.50.1700 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycoside hydrolase family 3 C-terminal domain 0.55 49.0 4.30e-01 96.7% 81.9%
2v4uA00 3.40.50.880 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Class I glutamine amidotransferase (GATase) domain 0.55 47.0 3.74e-01 97.5% 91.4%
2i5bA00 3.40.1190.20 Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase 0.54 48.0 3.71e-01 96.7% 86.2%
3ea0A00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.54 48.0 3.85e-01 96.7% 98.3%
2iu4A01 3.40.50.10440 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Dihydroxyacetone kinase; domain 1 0.54 48.0 4.32e-01 98.4% 78.9%
1t5bB00 3.40.50.360 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Flavodoxin domain 0.54 46.0 4.00e-01 96.7% 97.0%
1lw7A02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.54 47.0 4.33e-01 95.9% 98.1%
1efpB00 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.53 44.0 3.55e-01 90.2% 76.0%
7essA01 3.30.420.140 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › YqgF/RNase H-like domain 0.53 47.0 4.63e-01 97.5% 97.0%
3qxcA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.53 47.0 3.85e-01 97.5% 94.2%
2p4hX00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.53 47.0 3.54e-01 99.2% 74.8%
2cunA02 3.40.50.1260 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Phosphoglycerate kinase, N-terminal domain 0.53 45.0 3.82e-01 93.4% 98.0%
2c54A01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.52 46.0 4.07e-01 99.2% 90.2%
4dqlA03 3.40.50.80 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module 0.52 41.0 3.82e-01 86.1% 96.9%
6qu3A02 3.40.50.450 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.52 46.0 4.02e-01 100.0% 94.8%
3eozB01 3.40.50.1240 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Phosphoglycerate mutase-like 0.51 40.0 3.66e-01 83.6% 70.1%
2dcnA00 3.40.1190.20 Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase 0.51 44.0 3.34e-01 96.7% 84.7%
4p63D00 3.40.910.10 Alpha Beta › 3-Layer(aba) Sandwich › Deoxyhypusine Synthase › Deoxyhypusine synthase 0.51 43.0 3.27e-01 95.1% 82.4%
3cm0A00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.51 44.0 3.90e-01 97.5% 97.8%
3qyfA01 3.40.50.10770 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Hypothetical protein VC1899 like domain (Restriction endonuclease-like) 0.51 45.0 4.13e-01 100.0% 93.9%
1u3dA01 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.50 40.0 3.73e-01 86.9% 78.9%
2qhpA00 3.40.1190.20 Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase 0.50 44.0 3.38e-01 97.5% 89.9%
ECOD (72)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3165571 2006.1.3.2 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim 0.92 88.0 7.81e-01 100.0% 97.0%
4442595 2006.1.3.2 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim 0.92 89.0 6.21e-01 100.0% 42.5%
3953940 2006.1.3.2 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim 0.92 88.0 8.06e-01 99.2% 91.3%
3838295 2006.1.3.2 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim 0.90 83.0 8.41e-01 99.2% 97.5%
3330964 2006.1.3.2 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim 0.89 85.0 7.46e-01 100.0% 76.5%
4392313 2006.1.3.2 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim 0.89 84.0 7.67e-01 99.2% 97.4%
5001224 2006.1.3.0 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain 0.88 84.0 6.95e-01 99.2% 98.5%
4418350 2006.1.3.2 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim 0.88 84.0 7.01e-01 100.0% 96.9%
5036017 2006.1.3.2 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim 0.88 84.0 6.60e-01 100.0% 73.9%
4638791 2006.1.3.2 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim 0.87 80.0 6.85e-01 97.5% 95.7%
1572168 2006.1.3.2 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim 0.86 81.0 6.97e-01 99.2% 96.6%
3655189 2006.1.3.2 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim 0.85 74.0 7.67e-01 100.0% 95.7%
3594771 2006.1.3.0 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain 0.85 81.0 7.26e-01 100.0% 98.1%
4976525 2006.1.3.0 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain 0.85 80.0 7.23e-01 100.0% 100.0%
1144578 2006.1.3.2 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim 0.84 79.0 6.88e-01 99.2% 91.4%
5071480 2006.1.3.2 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim 0.84 79.0 7.07e-01 100.0% 93.9%
3944064 2006.1.3.2 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim 0.84 78.0 6.36e-01 100.0% 71.6%
3692627 2006.1.3.2 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim 0.83 79.0 6.73e-01 100.0% 97.3%
3623038 2006.1.3.2 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim 0.83 78.0 6.80e-01 100.0% 96.0%
4930519 2006.1.3.2 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim 0.83 78.0 7.14e-01 100.0% 98.7%
None — 0.82 77.0 7.04e-01 100.0% 98.7%
5051950 2006.1.3.2 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim 0.82 76.0 6.92e-01 98.4% 98.7%
3926546 2006.1.3.2 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim 0.82 77.0 6.79e-01 100.0% 96.5%
4283078 2006.1.3.2 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim 0.82 77.0 7.04e-01 100.0% 97.4%
3440696 2006.1.3.2 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim 0.81 77.0 7.11e-01 100.0% 95.3%
4990152 2006.1.3.2 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim 0.81 77.0 7.43e-01 100.0% 99.3%
4981101 2006.1.3.0 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain 0.80 76.0 7.33e-01 99.2% 100.0%
None — 0.80 74.0 7.28e-01 98.4% 99.2%
5005178 2006.1.3.0 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain 0.80 74.0 6.84e-01 97.5% 98.0%
3590579 2006.1.3.2 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim 0.80 74.0 6.78e-01 99.2% 98.7%
4971254 2006.1.3.0 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain 0.79 73.0 7.12e-01 97.5% 100.0%
4954869 2006.1.3.2 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim 0.77 73.0 7.12e-01 100.0% 98.5%
4880710 2006.1.3.2 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim 0.76 70.0 5.99e-01 100.0% 87.4%
4934403 2006.1.3.2 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim 0.75 71.0 6.42e-01 97.5% 91.6%
5008810 2006.1.3.2 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim 0.75 72.0 6.93e-01 100.0% 95.6%
4305698 2006.1.3.6 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim_2 0.73 59.0 5.89e-01 97.5% 82.4%
4504313 2006.1.3.6 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim_2 0.72 59.0 5.85e-01 99.2% 84.0%
3967801 2006.1.3.16 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › DUF1835 0.69 64.0 5.52e-01 100.0% 96.8%
5009494 7522.1.1.0 ↗ a/b three-layered sandwiches › TK C-terminal domain-like › TK C-terminal domain-like › TK C-terminal domain-like 0.67 53.0 5.23e-01 97.5% 77.7%
5024065 2006.1.3.2 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim 0.66 57.0 5.48e-01 99.2% 82.2%
5064221 7522.1.1.0 ↗ a/b three-layered sandwiches › TK C-terminal domain-like › TK C-terminal domain-like › TK C-terminal domain-like 0.65 51.0 4.60e-01 97.5% 61.2%
3285475 2006.1.3.7 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim_4 0.65 56.0 5.43e-01 100.0% 83.7%
4017112 2003.1.1.3 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short 0.60 39.0 2.95e-01 97.5% 26.8%
3279797 2007.2.1.3 ↗ a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › Flavoproteins › FMN_red 0.60 53.0 4.56e-01 97.5% 87.1%
4863091 2004.1.1.73 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MMR_HSR1 0.59 52.0 4.59e-01 97.5% 82.4%
3279729 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.58 53.0 4.12e-01 97.5% 91.9%
5017064 2007.1.8.1 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Uroporphyrinogen III synthase (U3S, HemD) › HEM4 0.58 51.0 4.99e-01 95.9% 100.0%
None — 0.58 51.0 3.88e-01 97.5% 92.7%
4976814 2003.1.9.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › Activating enzymes of the ubiquitin-like proteins 0.57 52.0 4.10e-01 99.2% 90.0%
4954544 2484.1.1.77 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Terminase_6C 0.56 51.0 4.33e-01 96.7% 83.2%
5052194 2007.15.1.0 ↗ a/b three-layered sandwiches › Flavodoxin-like › N-deoxyribosyltransferase › N-deoxyribosyltransferase 0.56 43.0 4.30e-01 86.9% 80.0%
3280738 2007.1.4.0 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Phosphofructokinase N-terminal domain 0.55 41.0 4.46e-01 92.6% 100.0%
3940369 2007.9.1.0 ↗ a/b three-layered sandwiches › Flavodoxin-like › Toll/Interleukin receptor TIR domain › Toll/Interleukin receptor TIR domain 0.55 49.0 4.65e-01 98.4% 93.1%
3707575 2484.1.1.74 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Tex_YqgF 0.54 48.0 4.44e-01 100.0% 91.3%
4933212 2003.1.4.3 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › DHS-like NAD/FAD-binding domain › DS 0.54 45.0 3.42e-01 93.4% 82.8%
4967351 2007.1.3.4 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › B12-binding 0.53 48.0 4.18e-01 99.2% 82.2%
4931799 7533.1.1.1 ↗ a/b three-layered sandwiches › Phosphoglycerate kinase domain 2 › Phosphoglycerate kinase domain 2 › Phosphoglycerate kinase domain 2 › PGK 0.53 46.0 3.75e-01 93.4% 88.0%
4974821 2007.1.3.4 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › B12-binding 0.53 47.0 4.08e-01 99.2% 77.9%
4084031 2007.1.3.4 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › B12-binding 0.53 48.0 3.93e-01 100.0% 69.1%
5062114 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.52 44.0 4.38e-01 100.0% 88.8%
3956789 2484.1.1.144 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DEDD_Tnp_IS110 0.52 45.0 4.26e-01 100.0% 77.3%
5006993 7533.1.1.1 ↗ a/b three-layered sandwiches › Phosphoglycerate kinase domain 2 › Phosphoglycerate kinase domain 2 › Phosphoglycerate kinase domain 2 › PGK 0.52 44.0 3.65e-01 91.8% 89.5%
5081047 2007.1.1.1 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Class I glutamine amidotransferase-like › GATase 0.52 44.0 3.60e-01 96.7% 93.2%
4984210 2003.1.4.3 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › DHS-like NAD/FAD-binding domain › DS 0.52 44.0 3.32e-01 94.3% 81.9%
5076009 7533.1.1.1 ↗ a/b three-layered sandwiches › Phosphoglycerate kinase domain 2 › Phosphoglycerate kinase domain 2 › Phosphoglycerate kinase domain 2 › PGK 0.51 45.0 3.77e-01 95.9% 93.8%
5001177 2007.1.11.0 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › L-fucose isomerase, N-terminal and second domains 0.51 44.0 4.34e-01 96.7% 92.6%
5051289 2007.1.3.4 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › B12-binding 0.51 46.0 3.94e-01 100.0% 77.9%
4948183 7533.1.1.1 ↗ a/b three-layered sandwiches › Phosphoglycerate kinase domain 2 › Phosphoglycerate kinase domain 2 › Phosphoglycerate kinase domain 2 › PGK 0.51 44.0 3.68e-01 95.9% 90.5%
4864981 2007.1.14.7 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Chelatase-like › HGD-D 0.51 44.0 4.00e-01 97.5% 73.2%
3604297 2484.1.1.68 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_H_2 0.51 45.0 3.98e-01 97.5% 99.4%
4960360 2002.1.1.120 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Radical_SAM 0.50 40.0 2.93e-01 85.2% 67.6%
3276368 2004.1.1.598 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › PF29907 0.50 44.0 3.92e-01 97.5% 88.6%
D3 medium residues 159-193_418-462_487-523
PDB
Domain cluster: rep: DNA_topoisomerase_1__YP_003986717__Acanthamoeba_polyphaga_mimivirus__212035__D157-185_471-514_550-565
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF01131.26 best Topoisom_bac 60.7 1.80e-16 73.5% 18.0%
D4 medium residues 194-230_355-417_463-486
PDB
D5 medium residues 231-354
PDB
Domain cluster: rep: KX077896.1__ANM47700.1__X__00069__D72-191
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF01131.26 best Topoisom_bac 122.9 2.40e-35 100.0% 32.5%
CATH (11)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1cy9A01 1.10.290.10 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; domain 4 › Topoisomerase I, domain 4 0.81 74.0 7.60e-01 95.2% 100.0%
6k8nA02 1.10.290.10 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; domain 4 › Topoisomerase I, domain 4 0.78 66.0 6.74e-01 88.7% 100.0%
1gkuB08 1.10.290.10 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; domain 4 › Topoisomerase I, domain 4 0.78 68.0 6.97e-01 91.1% 100.0%
4cgyA04 1.10.290.10 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; domain 4 › Topoisomerase I, domain 4 0.77 70.0 6.98e-01 95.2% 100.0%
1i7dA04 1.10.290.10 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; domain 4 › Topoisomerase I, domain 4 0.76 68.0 6.79e-01 94.4% 100.0%
1p4xA02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.72 37.0 3.80e-01 80.6% 51.2%
5e1wA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.71 37.0 3.33e-01 82.3% 38.1%
5dymA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.71 39.0 4.45e-01 81.5% 70.8%
4yjmC00 3.30.1390.10 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein L30; Chain: A, › Ribosomal protein L7/L12, C-terminal domain/Adaptor protein ClpS 0.59 30.0 3.63e-01 91.1% 73.5%
2zc2A00 1.10.10.630 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › DnaD domain-like 0.54 25.0 3.05e-01 82.3% 66.7%
1lzwA00 3.30.1390.10 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein L30; Chain: A, › Ribosomal protein L7/L12, C-terminal domain/Adaptor protein ClpS 0.50 27.0 3.05e-01 91.1% 67.0%
ECOD (47)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3368826 101.1.2.19 ↗ alpha arrays › HTH › HTH › winged helix domain › Topoisom_bac 0.86 81.0 7.71e-01 98.4% 100.0%
3876302 101.1.2.206 ↗ alpha arrays › HTH › HTH › winged helix domain › SAMD1_WH 0.86 39.0 4.25e-01 75.0% 52.4%
4006756 101.1.2.19 ↗ alpha arrays › HTH › HTH › winged helix domain › Topoisom_bac 0.84 76.0 5.55e-01 95.2% 41.0%
3593806 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.84 78.0 7.47e-01 97.6% 100.0%
3472278 101.1.2.206 ↗ alpha arrays › HTH › HTH › winged helix domain › SAMD1_WH 0.84 40.0 5.15e-01 75.8% 77.3%
4073954 101.1.2.19 ↗ alpha arrays › HTH › HTH › winged helix domain › Topoisom_bac 0.84 78.0 7.55e-01 97.6% 100.0%
4335818 101.1.2.19 ↗ alpha arrays › HTH › HTH › winged helix domain › Topoisom_bac 0.82 76.0 7.30e-01 97.6% 100.0%
3518858 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.82 39.0 4.90e-01 75.8% 72.5%
5001225 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.82 76.0 7.37e-01 96.8% 100.0%
5008811 101.1.2.19 ↗ alpha arrays › HTH › HTH › winged helix domain › Topoisom_bac 0.81 74.0 7.32e-01 96.0% 100.0%
5078217 101.1.2.19 ↗ alpha arrays › HTH › HTH › winged helix domain › Topoisom_bac 0.81 57.0 6.49e-01 75.8% 94.7%
3612398 101.1.2.19 ↗ alpha arrays › HTH › HTH › winged helix domain › Topoisom_bac 0.81 74.0 7.54e-01 96.0% 100.0%
3590582 101.1.2.19 ↗ alpha arrays › HTH › HTH › winged helix domain › Topoisom_bac 0.79 70.0 6.96e-01 94.4% 100.0%
3176697 101.1.2.19 ↗ alpha arrays › HTH › HTH › winged helix domain › Topoisom_bac 0.79 72.0 6.82e-01 96.8% 100.0%
4948253 2006.1.3.30 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Topoisom_bac 0.79 51.0 3.38e-01 100.0% 18.8%
5021952 101.1.2.19 ↗ alpha arrays › HTH › HTH › winged helix domain › Topoisom_bac 0.79 73.0 7.08e-01 98.4% 100.0%
5051951 101.1.2.19 ↗ alpha arrays › HTH › HTH › winged helix domain › Topoisom_bac 0.78 70.0 6.95e-01 95.2% 100.0%
3594756 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.78 71.0 7.00e-01 96.0% 100.0%
None — 0.78 37.0 3.99e-01 75.8% 53.3%
4987355 101.1.2.19 ↗ alpha arrays › HTH › HTH › winged helix domain › Topoisom_bac 0.78 70.0 6.98e-01 94.4% 100.0%
3305633 101.1.2.19 ↗ alpha arrays › HTH › HTH › winged helix domain › Topoisom_bac 0.78 69.0 6.96e-01 94.4% 100.0%
5000123 101.1.2.19 ↗ alpha arrays › HTH › HTH › winged helix domain › Topoisom_bac 0.77 69.0 6.71e-01 94.4% 100.0%
4466579 101.1.2.19 ↗ alpha arrays › HTH › HTH › winged helix domain › Topoisom_bac 0.77 69.0 6.83e-01 94.4% 100.0%
4602152 101.1.2.19 ↗ alpha arrays › HTH › HTH › winged helix domain › Topoisom_bac 0.77 68.0 6.70e-01 92.7% 100.0%
4976526 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.77 66.0 6.56e-01 90.3% 100.0%
4319228 101.1.2.19 ↗ alpha arrays › HTH › HTH › winged helix domain › Topoisom_bac 0.77 69.0 6.86e-01 95.2% 100.0%
4943299 101.1.2.19 ↗ alpha arrays › HTH › HTH › winged helix domain › Topoisom_bac 0.77 68.0 6.86e-01 93.5% 100.0%
4971255 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.77 66.0 6.65e-01 91.1% 100.0%
4363124 101.1.2.19 ↗ alpha arrays › HTH › HTH › winged helix domain › Topoisom_bac 0.76 70.0 6.85e-01 98.4% 100.0%
4981102 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.76 69.0 6.95e-01 96.0% 100.0%
3756243 101.1.2.19 ↗ alpha arrays › HTH › HTH › winged helix domain › Topoisom_bac 0.76 66.0 6.78e-01 91.9% 100.0%
3590144 101.1.2.19 ↗ alpha arrays › HTH › HTH › winged helix domain › Topoisom_bac 0.76 68.0 6.71e-01 95.2% 100.0%
4960284 101.1.2.19 ↗ alpha arrays › HTH › HTH › winged helix domain › Topoisom_bac 0.76 68.0 6.85e-01 95.2% 100.0%
3989662 101.1.2.54 ↗ alpha arrays › HTH › HTH › winged helix domain › Penicillinase_R 0.75 40.0 4.01e-01 78.2% 52.0%
4933036 101.1.2.19 ↗ alpha arrays › HTH › HTH › winged helix domain › Topoisom_bac 0.75 68.0 6.84e-01 96.8% 100.0%
5070343 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.75 39.0 4.61e-01 81.5% 71.1%
5005179 101.1.2.19 ↗ alpha arrays › HTH › HTH › winged helix domain › Topoisom_bac 0.73 65.0 6.56e-01 94.4% 100.0%
2585 101.1.2.231 ↗ alpha arrays › HTH › HTH › winged helix domain › Staph_reg_Sar_Rot 0.72 37.0 3.78e-01 80.6% 50.4%
5045747 101.1.2.48 ↗ alpha arrays › HTH › HTH › winged helix domain › PadR 0.70 39.0 4.49e-01 81.5% 74.4%
3741065 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.70 39.0 4.44e-01 95.2% 72.6%
4047911 101.1.2.231 ↗ alpha arrays › HTH › HTH › winged helix domain › Staph_reg_Sar_Rot 0.69 37.0 3.67e-01 82.3% 50.0%
3321732 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.68 39.0 4.36e-01 87.9% 71.0%
3310977 101.1.2.12 ↗ alpha arrays › HTH › HTH › winged helix domain › DEP 0.62 34.0 4.55e-01 73.4% 98.6%
3256849 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.59 36.0 4.21e-01 75.8% 85.6%
5049104 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.57 36.0 3.30e-01 97.6% 48.1%
4261887 7579.1.1.96 ↗ a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Peptidase_S9, Abhydrolase_1 0.54 42.0 3.27e-01 83.1% 73.7%
3724780 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.51 38.0 2.94e-01 76.6% 48.5%
D6 medium residues 620-658
PDB