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putative_DNA_topoisomerase_IB
Euk-VirCafeteria_roenbergensis_virus_BV-PW1
putative_DNA_topoisomerase_IB__YP_003969784__Cafeteria_roenbergensis_virus_BV-PW1__693272
Identity
- Accession:
- YP_003969784 ↗
- Protein ID:
- putative_DNA_topoisomerase_IB
- Kingdom:
- euk
Quality
70.5
mean pLDDT
Taxonomy
Bamfordvirae›
Nucleocytoviricota›
Megaviricetes›
Imitervirales›
Mimiviridae›
Rheavirus›
Cafeteria_roenbergensis_virus_BV-PW1
TaxID: 693272
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 231-366
Domain cluster:
rep: S16_GE16_scaffold_10741_prodigal-single.1__X__X__00162__D901-1023
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF01028.26 best | Topoisom_I | 168.7 | 1.90e-49 | 100.0% | 59.2% |
CATH (8)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1a31A03 | 3.90.15.10 | Alpha Beta › Alpha-Beta Complex › Topoisomerase I; Chain A, domain 3 › Topoisomerase I; Chain A, domain 3 | 0.97 | 95.0 | 9.12e-01 | 100.0% | 94.0% |
| 3m4aA03 | 3.90.15.10 | Alpha Beta › Alpha-Beta Complex › Topoisomerase I; Chain A, domain 3 › Topoisomerase I; Chain A, domain 3 | 0.87 | 67.0 | 7.23e-01 | 79.4% | 95.8% |
| 2h7fX02 | 3.90.15.10 | Alpha Beta › Alpha-Beta Complex › Topoisomerase I; Chain A, domain 3 › Topoisomerase I; Chain A, domain 3 | 0.87 | 82.0 | 6.57e-01 | 100.0% | 56.0% |
| 1a41A01 | 3.90.15.10 | Alpha Beta › Alpha-Beta Complex › Topoisomerase I; Chain A, domain 3 › Topoisomerase I; Chain A, domain 3 | 0.80 | 69.0 | 7.10e-01 | 97.8% | 96.9% |
| 5jk0B01 | 1.10.443.10 | Mainly Alpha › Orthogonal Bundle › hpI Integrase; Chain A › Intergrase catalytic core | 0.73 | 60.0 | 5.52e-01 | 91.2% | 68.2% |
| 1gccA00 | 3.30.730.10 | Alpha Beta › 2-Layer Sandwich › GCC-box Binding Domain › AP2/ERF domain | 0.70 | 20.0 | 3.02e-01 | 77.9% | 54.0% |
| 1e0bA00 | 2.40.50.40 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › | 0.52 | 24.0 | 3.40e-01 | 82.4% | 96.7% |
| 6j8yA00 | 3.70.10.10 | Alpha Beta › Box › Proliferating Cell Nuclear Antigen › | 0.51 | 34.0 | 2.80e-01 | 77.9% | 35.4% |
ECOD (27)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3599060 | 101.1.8.0 ↗ | alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes | 0.97 | 95.0 | 8.03e-01 | 100.0% | 67.5% |
| 3886079 | 101.1.8.2 ↗ | alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Topoisom_I | 0.97 | 95.0 | 7.99e-01 | 100.0% | 68.8% |
| 5044666 | 101.1.8.2 ↗ | alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Topoisom_I | 0.93 | 90.0 | 8.43e-01 | 100.0% | 95.6% |
| 3621756 | 101.1.8.2 ↗ | alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Topoisom_I | 0.92 | 84.0 | 8.37e-01 | 100.0% | 91.4% |
| 3973159 | 101.1.8.0 ↗ | alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes | 0.90 | 87.0 | 8.35e-01 | 100.0% | 94.0% |
| 3282325 | 101.1.8.2 ↗ | alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Topoisom_I | 0.90 | 86.0 | 8.20e-01 | 100.0% | 91.6% |
| 138326 | 101.1.8.2 ↗ | alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Topoisom_I | 0.85 | 81.0 | 8.07e-01 | 100.0% | 97.8% |
| 177048 | 101.1.8.2 ↗ | alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Topoisom_I | 0.85 | 81.0 | 7.80e-01 | 100.0% | 94.7% |
| 5035582 | 101.1.8.1 ↗ | alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Phage_integrase | 0.82 | 60.0 | 6.46e-01 | 94.1% | 88.7% |
| 4357768 | 101.1.8.0 ↗ | alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes | 0.77 | 64.0 | 6.57e-01 | 100.0% | 90.8% |
| 4210863 | 101.1.8.1 ↗ | alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Phage_integrase | 0.77 | 64.0 | 6.57e-01 | 100.0% | 90.8% |
| 4413773 | 101.1.8.1 ↗ | alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Phage_integrase | 0.77 | 64.0 | 6.43e-01 | 99.3% | 87.4% |
| 4453818 | 101.1.8.1 ↗ | alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Phage_integrase | 0.76 | 66.0 | 6.40e-01 | 99.3% | 83.3% |
| 5028306 | 101.1.8.1 ↗ | alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Phage_integrase | 0.74 | 60.0 | 5.46e-01 | 91.2% | 64.4% |
| 5027341 | 101.1.8.1 ↗ | alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Phage_integrase | 0.74 | 56.0 | 5.28e-01 | 99.3% | 66.3% |
| 5082761 | 101.1.8.1 ↗ | alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Phage_integrase | 0.69 | 59.0 | 6.07e-01 | 91.2% | 94.6% |
| 3291526 | 101.1.8.0 ↗ | alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes | 0.66 | 61.0 | 5.62e-01 | 100.0% | 92.0% |
| 4129953 | 325.1.7.3 ↗ | a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › Apocytochr_F_C | 0.60 | 27.0 | 3.76e-01 | 80.9% | 87.7% |
| 4099964 | 325.1.7.3 ↗ | a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › Apocytochr_F_C | 0.60 | 28.0 | 3.76e-01 | 80.9% | 87.7% |
| 4595815 | 325.1.7.3 ↗ | a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › Apocytochr_F_C | 0.59 | 28.0 | 3.70e-01 | 80.9% | 87.7% |
| 3969569 | 325.1.7.0 ↗ | a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif | 0.59 | 26.0 | 3.71e-01 | 80.9% | 91.7% |
| 3789900 | 220.1.1.5 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like › PID | 0.57 | 35.0 | 3.54e-01 | 80.9% | 60.0% |
| 4492087 | 325.1.7.3 ↗ | a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › Apocytochr_F_C | 0.57 | 28.0 | 3.67e-01 | 78.7% | 92.3% |
| 4435672 | 325.1.7.0 ↗ | a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif | 0.54 | 28.0 | 3.69e-01 | 84.6% | 100.0% |
| 4107506 | 325.1.7.0 ↗ | a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif | 0.53 | 27.0 | 3.64e-01 | 83.8% | 98.5% |
| 4680590 | 2.21.1.4 ↗ | beta barrels › OB-fold › Small protein B (SmpB) › Small protein B (SmpB) › SSO2105_N | 0.53 | 39.0 | 3.50e-01 | 76.5% | 89.7% |
| 3962048 | 227.1.1.15 ↗ | a+b two layers › DNA clamp › DNA clamp › DNA clamp › PF26035 | 0.52 | 31.0 | 3.51e-01 | 77.2% | 79.0% |
D2
high
residues 380-494
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF01028.26 best | Topoisom_I | 49.9 | 3.90e-13 | 69.6% | 31.6% |
CATH (31)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 6z01B03 | 1.10.132.10 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › | 0.79 | 69.0 | 6.22e-01 | 100.0% | 69.5% |
| 4x5mA00 | 1.20.1280.290 | Mainly Alpha › Up-down Bundle › Monooxygenase › | 0.77 | 50.0 | 5.68e-01 | 74.8% | 87.2% |
| 4rngC00 | 1.20.1280.290 | Mainly Alpha › Up-down Bundle › Monooxygenase › | 0.72 | 47.0 | 5.36e-01 | 74.8% | 91.6% |
| 3uo2B02 | 1.20.1280.20 | Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain | 0.69 | 47.0 | 5.46e-01 | 75.7% | 94.0% |
| 1a36A04 | 1.10.132.10 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › | 0.69 | 64.0 | 5.51e-01 | 100.0% | 70.3% |
| 7cj3A01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.69 | 55.0 | 4.18e-01 | 84.3% | 41.9% |
| 4fxdA04 | 3.90.1600.10 | Alpha Beta › Alpha-Beta Complex › Palm domain of DNA polymerase › B family DNA polymerase, palm domain | 0.68 | 52.0 | 4.69e-01 | 80.0% | 89.5% |
| 3ug9A02 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.67 | 49.0 | 3.92e-01 | 76.5% | 93.8% |
| 4zudA01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.67 | 46.0 | 3.56e-01 | 70.4% | 98.0% |
| 1wrdA00 | 1.20.58.160 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.67 | 44.0 | 4.81e-01 | 70.4% | 79.6% |
| 1vmgA00 | 1.10.287.1080 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like | 0.65 | 38.0 | 4.46e-01 | 84.3% | 82.9% |
| 8sbeA02 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.65 | 47.0 | 3.99e-01 | 80.9% | 46.5% |
| 3dyjA01 | 1.20.1420.10 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain | 0.64 | 48.0 | 4.31e-01 | 79.1% | 56.6% |
| 3vkgB03 | 1.20.58.1120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Dynein motor heavy chain, linker domain, subdomain 4 | 0.64 | 51.0 | 4.57e-01 | 83.5% | 77.6% |
| 1yfmA02 | 1.20.200.10 | Mainly Alpha › Up-down Bundle › Fumarase C; Chain A, domain 2 › Fumarase/aspartase (Central domain) | 0.63 | 49.0 | 3.68e-01 | 80.9% | 90.7% |
| 2oh3A01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.62 | 44.0 | 4.03e-01 | 72.2% | 66.0% |
| 6wngA02 | 1.20.200.10 | Mainly Alpha › Up-down Bundle › Fumarase C; Chain A, domain 2 › Fumarase/aspartase (Central domain) | 0.62 | 49.0 | 3.66e-01 | 81.7% | 89.7% |
| 2v0pA00 | 1.25.40.540 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › TAP42-like family | 0.61 | 49.0 | 4.00e-01 | 86.1% | 51.8% |
| 3craA02 | 1.10.287.1080 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like | 0.60 | 39.0 | 3.81e-01 | 80.9% | 58.6% |
| 5ffdA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.60 | 42.0 | 3.94e-01 | 72.2% | 67.9% |
| 1yvwA00 | 1.10.287.1080 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like | 0.59 | 38.0 | 4.18e-01 | 80.9% | 81.5% |
| 8anqA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.59 | 46.0 | 3.76e-01 | 84.3% | 78.1% |
| 1y6xA00 | 1.10.287.1080 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like | 0.58 | 39.0 | 4.35e-01 | 77.4% | 89.7% |
| 6epyA01 | 3.10.105.10 | Alpha Beta › Roll › Dipeptide-binding Protein; domain 3 › Dipeptide-binding Protein; Domain 3 | 0.57 | 46.0 | 3.57e-01 | 87.0% | 82.0% |
| 3f4mA00 | 1.20.1440.160 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Tumor necrosis factor alpha-induced protein 8-like | 0.57 | 43.0 | 3.92e-01 | 80.0% | 100.0% |
| 2p7vA00 | 1.20.120.1370 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Regulator of RNA polymerase sigma(70) subunit, domain 4 | 0.55 | 46.0 | 4.15e-01 | 87.8% | 90.1% |
| 4uiqB00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.54 | 44.0 | 4.12e-01 | 91.3% | 100.0% |
| 2zopA00 | 1.10.520.30 | Mainly Alpha › Orthogonal Bundle › Peroxidase; domain 1 › AF1862-like domain | 0.54 | 41.0 | 4.21e-01 | 79.1% | 100.0% |
| 3gi7A00 | 1.20.1270.180 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.53 | 39.0 | 4.06e-01 | 75.7% | 91.3% |
| 1yo7A00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.53 | 43.0 | 4.27e-01 | 87.0% | 85.8% |
| 8d7hD01 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.53 | 46.0 | 3.90e-01 | 90.4% | 98.3% |
ECOD (49)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3416926 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.82 | 61.0 | 5.28e-01 | 77.4% | 54.7% |
| 5013782 | 6155.1.1.0 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter | 0.78 | 50.0 | 6.06e-01 | 75.7% | 98.7% |
| 5027495 | 192.12.1.0 ↗ | alpha bundles › Long alpha-hairpin › Transcriptional repressor TraM › Transcriptional repressor TraM | 0.73 | 48.0 | 5.60e-01 | 78.3% | 91.8% |
| 3549089 | 109.4.1.1363 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HEAT, HEAT_EZ, TPR_IMB1 | 0.71 | 47.0 | 3.65e-01 | 73.9% | 32.1% |
| 3934154 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.70 | 44.0 | 5.13e-01 | 70.4% | 87.1% |
| 3186813 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.69 | 47.0 | 4.42e-01 | 79.1% | 57.8% |
| 3641813 | 604.6.1.1 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › GAT | 0.68 | 45.0 | 4.91e-01 | 70.4% | 81.1% |
| 4054419 | 604.12.1.78 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › FUSC | 0.68 | 48.0 | 4.16e-01 | 71.3% | 81.8% |
| 3605750 | 2484.1.1.34 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 | 0.67 | 58.0 | 3.37e-01 | 92.2% | 46.8% |
| 4000062 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.66 | 50.0 | 3.68e-01 | 78.3% | 97.9% |
| 4013045 | 159.1.2.1 ↗ | alpha bundles › all-alpha NTP pyrophosphatases › all-alpha NTP pyrophosphatases › MazG-related › PRA-PH | 0.66 | 41.0 | 4.36e-01 | 77.4% | 69.5% |
| 4190254 | 159.1.1.4 ↗ | alpha bundles › all-alpha NTP pyrophosphatases › all-alpha NTP pyrophosphatases › Hypothetical protein AF_0060 › PRA-PH | 0.66 | 42.0 | 4.31e-01 | 78.3% | 67.3% |
| 3700654 | 6110.1.1.1 ↗ | alpha superhelices › Linker domain of cytoplasmic dynein heavy chain › Linker domain of cytoplasmic dynein heavy chain › Linker domain of cytoplasmic dynein heavy chain › DHC_N2 | 0.65 | 52.0 | 3.42e-01 | 82.6% | 38.4% |
| 4024661 | 2003.1.4.0 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › DHS-like NAD/FAD-binding domain | 0.65 | 55.0 | 3.74e-01 | 92.2% | 30.1% |
| 3697260 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.65 | 55.0 | 4.54e-01 | 92.2% | 95.1% |
| 3958018 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.64 | 46.0 | 3.79e-01 | 79.1% | 43.1% |
| 5049251 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.64 | 48.0 | 3.92e-01 | 76.5% | 89.5% |
| 3688934 | 603.2.1.23 ↗ | alpha bundles › STAT-like › STAT › STAT › DUF7607 | 0.64 | 47.0 | 4.80e-01 | 84.3% | 79.1% |
| 3487856 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.63 | 53.0 | 3.53e-01 | 92.2% | 78.7% |
| 3934477 | 622.1.1.0 ↗ | alpha bundles › YvfG-like › HSC20 (HSCB), C-terminal oligomerisation domain › HSC20 (HSCB), C-terminal oligomerisation domain | 0.63 | 48.0 | 4.87e-01 | 82.6% | 80.9% |
| 3429331 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.62 | 43.0 | 3.53e-01 | 79.1% | 39.0% |
| 5067364 | 5067.1.1.2 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › SecD_SecF | 0.61 | 54.0 | 4.43e-01 | 94.8% | 92.7% |
| 3268234 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.61 | 42.0 | 3.91e-01 | 75.7% | 55.9% |
| 2055366 | 622.1.1.2 ↗ | alpha bundles › YvfG-like › HSC20 (HSCB), C-terminal oligomerisation domain › HSC20 (HSCB), C-terminal oligomerisation domain › HsbA | 0.61 | 41.0 | 4.82e-01 | 73.0% | 96.3% |
| 3228988 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.61 | 52.0 | 3.39e-01 | 92.2% | 91.7% |
| 4011171 | 192.15.1.126 ↗ | alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains › DUF7607 | 0.61 | 48.0 | 4.89e-01 | 92.2% | 83.5% |
| 1557160 | 5001.1.1.6 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Bac_rhodopsin | 0.61 | 47.0 | 3.57e-01 | 83.5% | 88.6% |
| 3622896 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.61 | 47.0 | 4.36e-01 | 80.0% | 86.4% |
| 3484828 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.60 | 48.0 | 4.44e-01 | 88.7% | 87.1% |
| 3409326 | 3930.1.1.6 ↗ | alpha bundles › Helical bundle insertion in helicase domains › Helical bundle in Hef helicase › Helical bundle in Hef helicase › Dicer_PBD | 0.60 | 43.0 | 4.04e-01 | 73.0% | 77.0% |
| 3576639 | 5067.1.1.0 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain | 0.60 | 51.0 | 4.08e-01 | 92.2% | 55.6% |
| 5056942 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.59 | 49.0 | 4.09e-01 | 91.3% | 92.2% |
| 3233751 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.59 | 46.0 | 3.65e-01 | 81.7% | 75.6% |
| 3457663 | 192.29.1.178 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › PF28703 | 0.58 | 43.0 | 4.49e-01 | 74.8% | 81.9% |
| 3209142 | 109.4.1.658 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Tti2 | 0.58 | 47.0 | 3.25e-01 | 87.8% | 34.2% |
| 5073361 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.57 | 47.0 | 4.01e-01 | 91.3% | 96.5% |
| 4029508 | 109.4.1.588 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › FPL | 0.57 | 48.0 | 3.11e-01 | 89.6% | 24.8% |
| 5030073 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.57 | 49.0 | 4.25e-01 | 92.2% | 93.1% |
| 3493827 | 622.4.1.0 ↗ | alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related | 0.57 | 47.0 | 4.53e-01 | 91.3% | 98.5% |
| 5073298 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.57 | 48.0 | 3.99e-01 | 93.0% | 71.7% |
| 3955766 | 3562.1.1.15 ↗ | alpha bundles › Calcium release-activated calcium channel protein 1 › Calcium release-activated calcium channel protein 1 › Calcium release-activated calcium channel protein 1 › YhhN | 0.56 | 49.0 | 4.04e-01 | 99.1% | 72.0% |
| 3295180 | 1075.5.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE | 0.55 | 47.0 | 4.53e-01 | 93.9% | 93.0% |
| 4361189 | 610.4.1.1 ↗ | alpha arrays › ERP29 C domain-like › YqeY domain › YqeY domain › YqeY | 0.54 | 41.0 | 3.63e-01 | 87.0% | 54.1% |
| 3304001 | 1075.5.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE | 0.54 | 47.0 | 4.49e-01 | 100.0% | 97.9% |
| 3710041 | 3615.1.1.0 ↗ | alpha bundles › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain | 0.54 | 44.0 | 3.59e-01 | 91.3% | 94.5% |
| 4535108 | 1075.5.1.8 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt_3 | 0.54 | 47.0 | 4.45e-01 | 98.3% | 87.9% |
| 3486401 | 3807.1.1.0 ↗ | alpha bundles › Yersinia protein kinase A (YpkA) Rho-GTPase binding domain › Yersinia protein kinase A (YpkA) Rho-GTPase binding domain › Yersinia protein kinase A (YpkA) Rho-GTPase binding domain | 0.53 | 45.0 | 3.61e-01 | 91.3% | 54.2% |
| 5031244 | 140.1.1.7 ↗ | alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › DALR_2 | 0.52 | 42.0 | 3.55e-01 | 89.6% | 63.8% |
| 3652633 | 3930.1.1.0 ↗ | alpha bundles › Helical bundle insertion in helicase domains › Helical bundle in Hef helicase › Helical bundle in Hef helicase | 0.52 | 41.0 | 4.04e-01 | 90.4% | 78.5% |
D3
medium
residues 32-119
D4
medium
residues 120-230