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putative_DNA_topoisomerase_IIA
Euk-VirCafeteria_roenbergensis_virus_BV-PW1
putative_DNA_topoisomerase_IIA__YP_003970179__Cafeteria_roenbergensis_virus_BV-PW1__693272
Identity
- Accession:
- YP_003970179 ↗
- Protein ID:
- putative_DNA_topoisomerase_IIA
- Kingdom:
- euk
Quality
88.1
mean pLDDT
Taxonomy
Bamfordvirae›
Nucleocytoviricota›
Megaviricetes›
Imitervirales›
Mimiviridae›
Rheavirus›
Cafeteria_roenbergensis_virus_BV-PW1
TaxID: 693272
Cluster
View cluster (39 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 58-233
Domain cluster:
rep: IMGVR_UViG_3300039190_000305-3300039190-Ga0399989_003201_3_1937__D82-97_167-336
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF02518.32 best | HATPase_c | 26.5 | 1.00e-05 | 76.7% | 69.4% |
D2
high
residues 248-384
Domain cluster:
rep: DNA_gyrase_subunit_B__YP_009352802__Kaumoebavirus_Viruses.__X__D311-415
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00204.32 best | DNA_gyraseB | 68.7 | 6.20e-19 | 99.3% | 73.6% |
D3
medium
residues 1-57
Domain cluster:
rep: KX236333.1__ANH51366.1__PC14_00073__00073__D1-50
CATH (3)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1pvgA01 | 3.30.565.10 | Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain | 0.95 | 78.0 | 4.92e-01 | 86.0% | 20.9% |
| 1cx8A01 | 3.40.630.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Zn peptidases | 0.51 | 38.0 | 2.46e-01 | 84.2% | 45.3% |
| 1oi2A02 | 3.30.1180.20 | Alpha Beta › 2-Layer Sandwich › Hypothetical Protein Tm841; Chain: A;domain 3 › Dihydroxyacetone kinase; domain 2 | 0.50 | 37.0 | 2.79e-01 | 84.2% | 63.0% |
ECOD (13)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3594649 | 225.1.1.0 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0.89 | 81.0 | 5.13e-01 | 98.2% | 24.1% |
| 4617838 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.89 | 80.0 | 5.11e-01 | 98.2% | 24.1% |
| 3317524 | 225.1.1.0 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0.87 | 73.0 | 4.84e-01 | 93.0% | 24.3% |
| 4179803 | 4964.1.1.2 ↗ | alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › RNA_pol | 0.55 | 40.0 | 2.88e-01 | 84.2% | 40.0% |
| 3598294 | 226.1.1.0 ↗ | a+b two layers › POZ domain › POZ domain › POZ domain | 0.54 | 41.0 | 3.26e-01 | 86.0% | 40.0% |
| 4189845 | 4964.1.1.0 ↗ | alpha arrays › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I › helical bundle in Bacillus stearothermophilus-like DNA polymerase I | 0.54 | 39.0 | 2.74e-01 | 82.5% | 39.1% |
| 3733648 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.52 | 42.0 | 3.10e-01 | 100.0% | 90.8% |
| 3482756 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.52 | 39.0 | 2.57e-01 | 82.5% | 19.6% |
| 4171935 | 167.1.1.1 ↗ | alpha arrays › Ribosomal protein S7 › Ribosomal protein S7 › Ribosomal protein S7 › Ribosomal_S7 | 0.52 | 36.0 | 2.67e-01 | 94.7% | 26.2% |
| 3920450 | 2484.1.1.145 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_Tnp_1_7 | 0.52 | 36.0 | 2.47e-01 | 75.4% | 54.2% |
| 5006856 | 205.1.1.16 ↗ | a+b two layers › 4Fe-4S ferredoxin › 4Fe-4S ferredoxin › 4Fe-4S ferredoxin › Fer4_7 | 0.52 | 35.0 | 3.22e-01 | 70.2% | 68.9% |
| 4974371 | 213.1.1.25 ↗ | a+b three layers › Nat/Ivy › Acyl-CoA N-acyltransferases (Nat) › Acyl-CoA N-acyltransferases (Nat) › Acetyltransf_3 | 0.52 | 38.0 | 2.75e-01 | 86.0% | 57.6% |
| 3941757 | 101.1.9.32 ↗ | alpha arrays › HTH › HTH › Putative DNA-binding domain › ANT | 0.51 | 37.0 | 3.08e-01 | 87.7% | 81.5% |
D4
medium
residues 409-537_590-602
Domain cluster:
rep: term2_saliva_scaffold_1_prodigal-single.1__X__X__00117__D395-534_709-736
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF01751.29 best | Toprim | 45.8 | 7.60e-12 | 87.3% | 88.5% |
D5
medium
residues 538-589
Domain cluster:
rep: DNA_topoisomerase_II__YP_009506801__Tunisvirus_fontaine2__1421067__D565-621
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF16898.11 best | TOPRIM_C | 61.5 | 1.30e-16 | 100.0% | 41.4% |
D6
medium
residues 603-676
Domain cluster:
rep: DNA_topoisomerase_II__YP_009238657__Brazilian_marseillevirus__1813599__D609-672
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF16898.11 best | TOPRIM_C | 57.9 | 1.70e-15 | 90.5% | 44.5% |
D7
medium
residues 677-798
Domain cluster:
rep: DNA_topoisomerase_2__YP_009162467__Salmon_gill_poxvirus__1680908__D669-796
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00521.27 best | DNA_topoisoIV | 145.1 | 4.20e-42 | 100.0% | 27.6% |
D8
medium
residues 858-945
Domain cluster:
rep: IMGVR_UViG_3300007985_000017-3300007985-Ga0100381_100027569__D212-299
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00521.27 best | DNA_topoisoIV | 34.1 | 2.00e-08 | 98.9% | 15.3% |
CATH (82)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 8gccA02 | 3.30.1360.40 | Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › | 0.94 | 82.0 | 8.35e-01 | 90.9% | 100.0% |
| 3qx3B03 | 3.30.1360.40 | Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › | 0.93 | 89.0 | 8.42e-01 | 100.0% | 95.0% |
| 3l4jA04 | 3.30.1360.40 | Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › | 0.92 | 87.0 | 8.24e-01 | 100.0% | 95.1% |
| 3lpxB02 | 3.30.1360.40 | Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › | 0.86 | 75.0 | 7.37e-01 | 93.2% | 96.8% |
| 7qh2C03 | 3.30.70.2740 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.71 | 51.0 | 5.41e-01 | 75.0% | 96.2% |
| 3e8oB00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.70 | 50.0 | 4.83e-01 | 75.0% | 79.0% |
| 2pd1A01 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.70 | 50.0 | 4.95e-01 | 76.1% | 81.1% |
| 1y0hB00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.69 | 50.0 | 4.85e-01 | 76.1% | 80.6% |
| 4u9rA01 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.69 | 50.0 | 5.18e-01 | 76.1% | 96.3% |
| 4nfnA01 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.69 | 44.0 | 5.03e-01 | 83.0% | 90.6% |
| 2gffA00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.69 | 49.0 | 4.80e-01 | 75.0% | 81.2% |
| 2go8A01 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.69 | 46.0 | 4.93e-01 | 70.5% | 81.1% |
| 3kg0A00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.69 | 50.0 | 4.84e-01 | 76.1% | 81.4% |
| 2bj3D02 | 3.30.70.1150 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT-like. Chain A, domain 2 | 0.68 | 48.0 | 5.02e-01 | 73.9% | 80.2% |
| 3gz7B00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.68 | 49.0 | 4.73e-01 | 75.0% | 82.7% |
| 4dpoB00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.68 | 49.0 | 4.75e-01 | 76.1% | 79.2% |
| 1m1hA01 | 3.30.70.940 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › NusG, N-terminal domain | 0.68 | 47.0 | 4.55e-01 | 72.7% | 69.0% |
| 4hl9A00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.67 | 48.0 | 4.75e-01 | 75.0% | 84.0% |
| 1b24A01 | 3.10.28.10 | Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases | 0.67 | 50.0 | 4.94e-01 | 79.5% | 84.2% |
| 5w2fA01 | 3.30.780.10 | Alpha Beta › 2-Layer Sandwich › Translation Initiation Factor Eif1 › SUI1-like domain | 0.66 | 52.0 | 5.29e-01 | 84.1% | 89.5% |
| 4bfmA00 | 1.10.510.10 | Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 | 0.66 | 53.0 | 3.62e-01 | 86.4% | 44.7% |
| 2b4vA03 | 3.30.70.1970 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.66 | 49.0 | 4.71e-01 | 77.3% | 72.7% |
| 4lrjA01 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.66 | 45.0 | 4.83e-01 | 71.6% | 84.9% |
| 6vp6A01 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.66 | 45.0 | 4.62e-01 | 71.6% | 74.7% |
| 1blxA01 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.66 | 45.0 | 4.45e-01 | 70.5% | 88.0% |
| 2zbcA01 | 3.30.70.920 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Lrp/AsnC effector binding domain/regulation of amino acid metabolism (RAM) domain | 0.66 | 45.0 | 4.88e-01 | 73.9% | 86.3% |
| 1el6A03 | 3.90.1160.10 | Alpha Beta › Alpha-Beta Complex › Baseplate Structural Protein Gp11; Chain: A, domain 3 › Baseplate structural protein gp11, finger domain | 0.65 | 48.0 | 4.44e-01 | 76.1% | 85.3% |
| 6k3lB02 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.65 | 44.0 | 4.44e-01 | 70.5% | 74.7% |
| 4qjvB00 | 3.30.1360.10 | Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › RNA polymerase, RBP11-like subunit | 0.65 | 51.0 | 4.99e-01 | 84.1% | 84.0% |
| 4c57B00 | 1.10.510.10 | Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 | 0.65 | 52.0 | 3.60e-01 | 87.5% | 57.1% |
| 2cdqA03 | 3.30.70.260 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain | 0.65 | 51.0 | 5.19e-01 | 85.2% | 91.7% |
| 4v1al00 | 3.30.780.10 | Alpha Beta › 2-Layer Sandwich › Translation Initiation Factor Eif1 › SUI1-like domain | 0.65 | 56.0 | 4.94e-01 | 96.6% | 81.2% |
| 5yppA00 | 3.30.70.260 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain | 0.65 | 46.0 | 4.58e-01 | 73.9% | 73.3% |
| 1fvqA00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.65 | 46.0 | 4.91e-01 | 73.9% | 91.7% |
| 6ruiK00 | 3.30.1360.10 | Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › RNA polymerase, RBP11-like subunit | 0.65 | 52.0 | 4.94e-01 | 87.5% | 79.6% |
| 4o1pD02 | 1.10.510.10 | Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 | 0.65 | 49.0 | 3.62e-01 | 83.0% | 53.2% |
| 4d9uA01 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.65 | 46.0 | 4.67e-01 | 83.0% | 75.0% |
| 2vz6B01 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.65 | 44.0 | 4.57e-01 | 71.6% | 84.3% |
| 2kjwA00 | 3.30.70.60 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S6/Translation elongation factor EF1B | 0.64 | 47.0 | 4.56e-01 | 76.1% | 75.0% |
| 3havA01 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.64 | 45.0 | 4.49e-01 | 83.0% | 71.9% |
| 5xogK00 | 3.30.1360.10 | Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › RNA polymerase, RBP11-like subunit | 0.64 | 53.0 | 4.89e-01 | 93.2% | 70.8% |
| 3ibwA00 | 3.30.70.260 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain | 0.64 | 46.0 | 4.79e-01 | 75.0% | 83.5% |
| 2f1fA01 | 3.30.70.260 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain | 0.64 | 45.0 | 4.71e-01 | 73.9% | 84.8% |
| 2kkhA01 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.64 | 45.0 | 4.77e-01 | 73.9% | 89.3% |
| 1zpvA00 | 3.30.70.260 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain | 0.63 | 46.0 | 4.68e-01 | 76.1% | 84.7% |
| 4dn9B00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.63 | 46.0 | 4.46e-01 | 76.1% | 79.4% |
| 6gmhK00 | 3.30.1360.10 | Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › RNA polymerase, RBP11-like subunit | 0.63 | 52.0 | 4.81e-01 | 92.0% | 69.6% |
| 2dgxA01 | 3.30.70.330 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain | 0.63 | 45.0 | 4.71e-01 | 75.0% | 88.7% |
| 2x7gA01 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.63 | 44.0 | 4.42e-01 | 71.6% | 77.3% |
| 2xhcA01 | 3.30.70.940 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › NusG, N-terminal domain | 0.63 | 44.0 | 4.32e-01 | 72.7% | 69.5% |
| 3fxzA01 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.63 | 46.0 | 4.49e-01 | 83.0% | 70.4% |
| 2dbbA02 | 3.30.70.920 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Lrp/AsnC effector binding domain/regulation of amino acid metabolism (RAM) domain | 0.63 | 44.0 | 4.37e-01 | 73.9% | 72.0% |
| 3i4pA02 | 3.30.70.920 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Lrp/AsnC effector binding domain/regulation of amino acid metabolism (RAM) domain | 0.62 | 43.0 | 4.46e-01 | 72.7% | 79.8% |
| 1a9nD00 | 3.30.70.330 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain | 0.62 | 45.0 | 4.52e-01 | 78.4% | 80.6% |
| 2yweA04 | 3.30.70.240 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.62 | 43.0 | 3.96e-01 | 75.0% | 55.3% |
| 2djwA01 | 3.30.70.920 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Lrp/AsnC effector binding domain/regulation of amino acid metabolism (RAM) domain | 0.62 | 43.0 | 4.62e-01 | 75.0% | 86.5% |
| 2clqA01 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.62 | 42.0 | 4.30e-01 | 70.5% | 76.5% |
| 2dt9A01 | 3.30.70.260 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain | 0.62 | 46.0 | 4.95e-01 | 84.1% | 97.3% |
| 1q5yC00 | 3.30.70.1150 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT-like. Chain A, domain 2 | 0.61 | 43.0 | 4.50e-01 | 75.0% | 82.9% |
| 1r89A03 | 3.30.70.590 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Poly(A) polymerase predicted RNA binding domain | 0.61 | 44.0 | 3.94e-01 | 78.4% | 74.6% |
| 3p96A02 | 3.30.70.260 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain | 0.61 | 43.0 | 4.46e-01 | 76.1% | 84.5% |
| 5mmiU01 | 3.30.70.330 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain | 0.61 | 43.0 | 4.46e-01 | 75.0% | 93.9% |
| 3c1mA02 | 3.30.2130.10 | Alpha Beta › 2-Layer Sandwich › VC0802-like › VC0802-like | 0.60 | 44.0 | 3.69e-01 | 78.4% | 43.9% |
| 2efpA02 | 3.30.70.920 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Lrp/AsnC effector binding domain/regulation of amino acid metabolism (RAM) domain | 0.60 | 42.0 | 4.13e-01 | 73.9% | 66.3% |
| 2j0wA03 | 3.30.70.260 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain | 0.60 | 47.0 | 4.89e-01 | 85.2% | 92.6% |
| 2f40A00 | 3.30.70.1750 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Uncharacterised protein PF11491 family, DUF3213 | 0.60 | 41.0 | 4.32e-01 | 71.6% | 83.8% |
| 5k9fA00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.60 | 42.0 | 4.06e-01 | 75.0% | 82.5% |
| 2qrrA00 | 3.30.70.260 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain | 0.59 | 42.0 | 4.16e-01 | 76.1% | 81.4% |
| 2q7eA02 | 3.30.930.10 | Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2 | 0.59 | 44.0 | 3.40e-01 | 80.7% | 55.2% |
| 8gz3B01 | 2.40.30.10 | Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Translation factors | 0.59 | 45.0 | 4.45e-01 | 81.8% | 91.4% |
| 1jyaB00 | 3.30.1460.10 | Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, › | 0.59 | 45.0 | 4.12e-01 | 84.1% | 74.4% |
| 2p92A00 | 3.30.70.1490 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Cysteine protease Prp | 0.58 | 46.0 | 4.57e-01 | 87.5% | 90.5% |
| 3oksA01 | 3.90.1150.10 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 | 0.56 | 50.0 | 3.97e-01 | 97.7% | 67.0% |
| 3tu3A00 | 3.30.1460.10 | Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, › | 0.56 | 42.0 | 3.89e-01 | 81.8% | 76.5% |
| 4o2zA01 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.56 | 43.0 | 3.65e-01 | 84.1% | 64.1% |
| 1s28A00 | 3.30.1460.10 | Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, › | 0.56 | 42.0 | 3.75e-01 | 81.8% | 68.5% |
| 5mmjh01 | 3.30.1370.30 | Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › | 0.55 | 43.0 | 4.65e-01 | 85.2% | 100.0% |
| 2jvfA00 | 3.30.1710.10 | Alpha Beta › 2-Layer Sandwich › top7, de novo designed protein › top7, de novo designed protein | 0.54 | 40.0 | 3.97e-01 | 79.5% | 100.0% |
| 3aqoA02 | 3.30.1360.200 | Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › | 0.52 | 40.0 | 3.54e-01 | 85.2% | 60.3% |
| 5dymA00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.52 | 37.0 | 3.68e-01 | 77.3% | 79.2% |
| 4hfsA00 | 2.60.120.1270 | Mainly Beta › Sandwich › Jelly Rolls › | 0.51 | 38.0 | 3.00e-01 | 80.7% | 96.1% |
| 1jsgA00 | 2.40.15.10 | Mainly Beta › Beta Barrel › Proto-oncogene - Oncogene Product P14tcl1 › TCL1/MTCP1 | 0.51 | 38.0 | 3.52e-01 | 79.5% | 82.0% |
ECOD (97)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3719735 | 4014.1.1.1 ↗ | a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV | 0.94 | 90.0 | 7.02e-01 | 100.0% | 57.0% |
| 3188905 | 4014.1.1.1 ↗ | a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV | 0.94 | 89.0 | 6.80e-01 | 100.0% | 56.1% |
| 3998667 | 4014.1.1.1 ↗ | a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV | 0.93 | 89.0 | 6.56e-01 | 100.0% | 52.8% |
| 2390536 | 4014.1.1.1 ↗ | a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV | 0.92 | 83.0 | 6.57e-01 | 94.3% | 55.6% |
| 3789606 | 4014.1.1.0 ↗ | a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase | 0.92 | 88.0 | 6.80e-01 | 100.0% | 58.2% |
| 3096551 | 4014.1.1.1 ↗ | a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV | 0.90 | 86.0 | 6.47e-01 | 100.0% | 55.1% |
| 3594650 | 4014.1.1.0 ↗ | a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase | 0.89 | 85.0 | 6.75e-01 | 100.0% | 56.9% |
| 3614277 | 4014.1.1.1 ↗ | a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV | 0.88 | 84.0 | 6.41e-01 | 100.0% | 50.6% |
| 3962339 | 4014.1.1.0 ↗ | a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase | 0.87 | 81.0 | 6.18e-01 | 100.0% | 59.5% |
| 4887990 | 4014.1.1.1 ↗ | a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV | 0.87 | 82.0 | 6.50e-01 | 100.0% | 58.4% |
| 3590557 | 4014.1.1.1 ↗ | a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV | 0.86 | 80.0 | 6.04e-01 | 100.0% | 55.9% |
| 4624017 | 4014.1.1.1 ↗ | a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV | 0.86 | 80.0 | 6.20e-01 | 100.0% | 58.3% |
| 4878007 | 101.1.2.9 ↗ | alpha arrays › HTH › HTH › winged helix domain › DNA_topoisoIV | 0.85 | 77.0 | 6.42e-01 | 95.5% | 64.8% |
| 4266765 | 4014.1.1.1 ↗ | a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV | 0.85 | 78.0 | 6.25e-01 | 100.0% | 59.4% |
| 5036213 | 304.4.1.0 ↗ | a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel | 0.70 | 50.0 | 5.00e-01 | 73.9% | 76.7% |
| 4937799 | 4956.1.1.0 ↗ | a+b two layers › ferredoxin-like domain in yeast RNA-polymerase beta-prime subunit › ferredoxin-like domain in yeast RNA-polymerase beta-prime subunit › ferredoxin-like domain in yeast RNA-polymerase beta-prime subunit | 0.69 | 47.0 | 5.16e-01 | 71.6% | 88.6% |
| 4997133 | 306.3.1.1 ↗ | a+b two layers › Glucose permease domain IIB-like › eIF1-like › eIF1-like › SUI1 | 0.69 | 56.0 | 5.47e-01 | 88.6% | 84.2% |
| 3838249 | 304.3.1.1 ↗ | a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain › HMA | 0.68 | 50.0 | 5.15e-01 | 78.4% | 87.1% |
| 4273759 | 305.1.1.2 ↗ | a+b two layers › DCoH-like › RBP11-like subunits of RNA polymerase › RBP11-like subunits of RNA polymerase › RNA_pol_L_2 | 0.67 | 54.0 | 5.20e-01 | 96.6% | 75.8% |
| 3843541 | 306.3.1.1 ↗ | a+b two layers › Glucose permease domain IIB-like › eIF1-like › eIF1-like › SUI1 | 0.67 | 53.0 | 4.95e-01 | 85.2% | 71.8% |
| 4502232 | 304.162.1.1 ↗ | a+b two layers › Alpha-beta plaits › Competence or damage-inducible protein CinA middle domain › Competence or damage-inducible protein CinA middle domain › CinA_KH | 0.67 | 48.0 | 4.98e-01 | 73.9% | 93.8% |
| 149487 | 206.1.1.11 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › APH | 0.67 | 54.0 | 3.83e-01 | 87.5% | 87.8% |
| 5054060 | 310.3.1.0 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › General secretion pathway protein M (EpsM) periplasmic domain-related › General secretion pathway protein M (EpsM) periplasmic domain-related | 0.67 | 45.0 | 4.66e-01 | 70.5% | 80.0% |
| 3611570 | 206.1.1.87 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase, RIO1 | 0.67 | 53.0 | 3.70e-01 | 86.4% | 52.8% |
| 3317802 | 304.8.1.45 ↗ | a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › bHLH-TF_ACT-like_plant | 0.67 | 51.0 | 5.05e-01 | 83.0% | 95.8% |
| 3960213 | 304.156.1.5 ↗ | a+b two layers › Alpha-beta plaits › DNA translocase FtsK N-terminal domain › DNA translocase FtsK N-terminal domain › PF31086 | 0.66 | 49.0 | 4.51e-01 | 78.4% | 69.6% |
| 5051424 | 304.4.1.3 ↗ | a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › YCII | 0.66 | 48.0 | 4.67e-01 | 75.0% | 84.2% |
| 3299923 | 304.3.1.0 ↗ | a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain | 0.66 | 47.0 | 4.91e-01 | 73.9% | 81.2% |
| 3998431 | 306.3.1.1 ↗ | a+b two layers › Glucose permease domain IIB-like › eIF1-like › eIF1-like › SUI1 | 0.66 | 52.0 | 4.87e-01 | 85.2% | 71.8% |
| 4962212 | 304.4.1.1 ↗ | a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › AsnC_trans_reg | 0.65 | 46.0 | 4.62e-01 | 73.9% | 73.3% |
| 4287179 | 304.4.1.1 ↗ | a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › AsnC_trans_reg | 0.65 | 46.0 | 4.68e-01 | 73.9% | 74.2% |
| 3822570 | 304.3.1.1 ↗ | a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain › HMA | 0.65 | 46.0 | 4.79e-01 | 73.9% | 83.7% |
| 3655963 | 304.8.1.0 ↗ | a+b two layers › Alpha-beta plaits › ACT-like › ACT-like | 0.65 | 47.0 | 5.20e-01 | 76.1% | 97.1% |
| 2531310 | 306.3.1.1 ↗ | a+b two layers › Glucose permease domain IIB-like › eIF1-like › eIF1-like › SUI1 | 0.65 | 51.0 | 4.65e-01 | 85.2% | 66.9% |
| 3312923 | 304.8.1.0 ↗ | a+b two layers › Alpha-beta plaits › ACT-like › ACT-like | 0.65 | 51.0 | 4.97e-01 | 84.1% | 95.8% |
| 3968732 | 304.4.1.1 ↗ | a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › AsnC_trans_reg | 0.65 | 45.0 | 4.44e-01 | 72.7% | 71.6% |
| 3250936 | 304.15.1.0 ↗ | a+b two layers › Alpha-beta plaits › Viral DNA-binding domain › Viral DNA-binding domain | 0.65 | 44.0 | 4.80e-01 | 70.5% | 95.7% |
| 5018607 | 304.128.1.0 ↗ | a+b two layers › Alpha-beta plaits › ferredoxin-like domain in periplasmic region of MacB › ferredoxin-like domain in periplasmic region of MacB | 0.65 | 47.0 | 4.68e-01 | 76.1% | 85.6% |
| 5031028 | 304.4.1.0 ↗ | a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel | 0.65 | 46.0 | 4.26e-01 | 73.9% | 60.0% |
| 4946747 | 304.3.1.0 ↗ | a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain | 0.65 | 46.0 | 4.62e-01 | 75.0% | 75.6% |
| 3829402 | 304.8.1.0 ↗ | a+b two layers › Alpha-beta plaits › ACT-like › ACT-like | 0.65 | 54.0 | 5.62e-01 | 95.5% | 100.0% |
| 3303164 | 304.8.1.0 ↗ | a+b two layers › Alpha-beta plaits › ACT-like › ACT-like | 0.64 | 44.0 | 5.00e-01 | 71.6% | 96.9% |
| 4940919 | 304.102.1.2 ↗ | a+b two layers › Alpha-beta plaits › Pseudouridine synthase › Pseudouridine synthase › TruD | 0.64 | 50.0 | 3.94e-01 | 86.4% | 94.0% |
| 330634 | 304.16.1.1 ↗ | a+b two layers › Alpha-beta plaits › eEF-1beta-like › eEF-1beta-like › EF1_GNE | 0.64 | 45.0 | 4.46e-01 | 72.7% | 82.4% |
| 4954911 | 304.8.1.2 ↗ | a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › ACT | 0.64 | 46.0 | 4.67e-01 | 75.0% | 78.8% |
| 4505080 | 242.1.1.2 ↗ | a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_2 | 0.64 | 46.0 | 4.16e-01 | 77.3% | 67.2% |
| 4961378 | 304.4.1.0 ↗ | a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel | 0.64 | 45.0 | 4.49e-01 | 73.9% | 73.3% |
| 3490869 | 304.3.1.1 ↗ | a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain › HMA | 0.64 | 45.0 | 4.66e-01 | 73.9% | 85.0% |
| 3345154 | 304.3.1.0 ↗ | a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain | 0.63 | 44.0 | 4.67e-01 | 73.9% | 83.3% |
| 3306024 | 304.8.1.0 ↗ | a+b two layers › Alpha-beta plaits › ACT-like › ACT-like | 0.63 | 55.0 | 5.16e-01 | 98.9% | 91.8% |
| 4529236 | 207.11.1.1 ↗ | beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Urease accessory protein ureH › Urease accessory protein ureH › UreD | 0.63 | 54.0 | 3.91e-01 | 97.7% | 93.3% |
| 3738706 | 320.1.1.0 ↗ | a+b two layers › R3H domain-like › R3H domain › R3H domain | 0.63 | 48.0 | 4.36e-01 | 81.8% | 62.5% |
| 3232572 | 304.8.1.0 ↗ | a+b two layers › Alpha-beta plaits › ACT-like › ACT-like | 0.63 | 44.0 | 4.66e-01 | 72.7% | 90.7% |
| 3517813 | 306.3.1.1 ↗ | a+b two layers › Glucose permease domain IIB-like › eIF1-like › eIF1-like › SUI1 | 0.63 | 53.0 | 5.36e-01 | 98.9% | 92.0% |
| 3750992 | 206.1.1.70 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase, ABC1 | 0.63 | 55.0 | 3.83e-01 | 98.9% | 93.4% |
| 4162926 | 241.1.1.3 ↗ | a+b two layers › Type III secretory system chaperone-like › Type III secretory system chaperone › Type III secretory system chaperone › CesT | 0.63 | 47.0 | 4.18e-01 | 80.7% | 72.3% |
| 3278158 | 304.4.1.1 ↗ | a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › AsnC_trans_reg | 0.63 | 44.0 | 4.51e-01 | 73.9% | 78.8% |
| 3269732 | 206.1.1.49 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › DUF5898 | 0.63 | 54.0 | 4.10e-01 | 95.5% | 60.5% |
| 4934117 | 242.1.1.0 ↗ | a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases | 0.62 | 45.0 | 4.62e-01 | 77.3% | 87.1% |
| 3954190 | 206.1.1.11 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › APH | 0.62 | 55.0 | 4.05e-01 | 100.0% | 90.4% |
| 4963469 | 242.1.1.0 ↗ | a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases | 0.62 | 44.0 | 4.16e-01 | 73.9% | 71.4% |
| 5002991 | 304.128.1.0 ↗ | a+b two layers › Alpha-beta plaits › ferredoxin-like domain in periplasmic region of MacB › ferredoxin-like domain in periplasmic region of MacB | 0.62 | 45.0 | 4.60e-01 | 76.1% | 81.2% |
| 3716681 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.62 | 55.0 | 3.76e-01 | 100.0% | 64.4% |
| 4658998 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.62 | 53.0 | 4.22e-01 | 95.5% | 75.0% |
| 4237289 | 207.11.1.1 ↗ | beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Urease accessory protein ureH › Urease accessory protein ureH › UreD | 0.62 | 54.0 | 3.88e-01 | 97.7% | 93.5% |
| 5045792 | 304.4.1.0 ↗ | a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel | 0.62 | 44.0 | 4.10e-01 | 76.1% | 59.1% |
| 5004413 | 304.128.1.0 ↗ | a+b two layers › Alpha-beta plaits › ferredoxin-like domain in periplasmic region of MacB › ferredoxin-like domain in periplasmic region of MacB | 0.62 | 44.0 | 4.73e-01 | 76.1% | 92.0% |
| 4979196 | 241.1.1.6 ↗ | a+b two layers › Type III secretory system chaperone-like › Type III secretory system chaperone › Type III secretory system chaperone › YbjN | 0.62 | 46.0 | 4.13e-01 | 79.5% | 75.2% |
| 3198542 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.61 | 54.0 | 3.87e-01 | 97.7% | 48.8% |
| 4946187 | 241.6.1.0 ↗ | a+b two layers › Type III secretory system chaperone-like › Arp2/3 complex subunits › Arp2/3 complex subunits | 0.61 | 47.0 | 4.23e-01 | 83.0% | 67.2% |
| 4086765 | 242.1.1.5 ↗ | a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › WhiA_N | 0.61 | 46.0 | 4.32e-01 | 80.7% | 70.9% |
| 3272845 | 206.1.1.70 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase, ABC1 | 0.61 | 55.0 | 3.59e-01 | 100.0% | 48.4% |
| 3171544 | 206.1.1.71 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase, Kdo | 0.61 | 53.0 | 3.60e-01 | 95.5% | 49.5% |
| 3598225 | 206.1.1.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase | 0.61 | 54.0 | 3.84e-01 | 100.0% | 55.6% |
| 3221492 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.61 | 55.0 | 3.56e-01 | 100.0% | 41.0% |
| 4064719 | 242.1.1.5 ↗ | a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › WhiA_N | 0.61 | 46.0 | 4.37e-01 | 80.7% | 77.1% |
| 3848271 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.61 | 54.0 | 3.78e-01 | 100.0% | 90.0% |
| 3655967 | 304.8.1.0 ↗ | a+b two layers › Alpha-beta plaits › ACT-like › ACT-like | 0.61 | 54.0 | 5.29e-01 | 100.0% | 92.6% |
| 4354775 | 304.102.1.2 ↗ | a+b two layers › Alpha-beta plaits › Pseudouridine synthase › Pseudouridine synthase › TruD | 0.61 | 47.0 | 3.77e-01 | 86.4% | 90.5% |
| 3924711 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.61 | 54.0 | 3.68e-01 | 100.0% | 88.7% |
| 3581740 | 206.1.1.71 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase, Kdo | 0.60 | 53.0 | 3.65e-01 | 100.0% | 92.8% |
| 3426902 | 304.8.1.0 ↗ | a+b two layers › Alpha-beta plaits › ACT-like › ACT-like | 0.60 | 47.0 | 4.60e-01 | 85.2% | 96.8% |
| 3964731 | 304.3.1.1 ↗ | a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain › HMA | 0.60 | 50.0 | 4.81e-01 | 90.9% | 93.0% |
| 3675126 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.60 | 53.0 | 3.64e-01 | 100.0% | 96.0% |
| 3709408 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.60 | 53.0 | 3.70e-01 | 100.0% | 74.7% |
| 3643150 | 304.8.1.0 ↗ | a+b two layers › Alpha-beta plaits › ACT-like › ACT-like | 0.60 | 50.0 | 5.13e-01 | 97.7% | 97.6% |
| 3614406 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.60 | 53.0 | 3.70e-01 | 100.0% | 74.9% |
| 2892779 | 206.1.1.71 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase, Kdo | 0.60 | 53.0 | 3.73e-01 | 100.0% | 93.0% |
| 3810458 | 304.8.1.0 ↗ | a+b two layers › Alpha-beta plaits › ACT-like › ACT-like | 0.59 | 53.0 | 5.16e-01 | 98.9% | 95.8% |
| 3598599 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.59 | 52.0 | 3.56e-01 | 100.0% | 93.6% |
| 3217898 | 206.1.1.70 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase, ABC1 | 0.59 | 52.0 | 3.60e-01 | 100.0% | 64.2% |
| 3467717 | 206.1.1.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase | 0.59 | 52.0 | 2.98e-01 | 100.0% | 21.4% |
| 3689719 | 206.1.1.11 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › APH | 0.58 | 51.0 | 3.56e-01 | 100.0% | 87.8% |
| 3947367 | 206.1.1.35 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › APH_6_hur | 0.57 | 51.0 | 3.63e-01 | 100.0% | 85.7% |
| 3184022 | 1.1.7.7 ↗ | beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › FAD_binding_6 | 0.56 | 42.0 | 3.77e-01 | 80.7% | 90.8% |
| 3602905 | 304.132.1.1 ↗ | a+b two layers › Alpha-beta plaits › ferredoxin-like domain in 2,3-bisphosphoglycerate-independent phosphoglycerate mutase › ferredoxin-like domain in 2,3-bisphosphoglycerate-independent phosphoglycerate mutase › PhosphMutase | 0.56 | 41.0 | 3.46e-01 | 77.3% | 87.7% |
| 2583503 | 304.156.1.0 ↗ | a+b two layers › Alpha-beta plaits › DNA translocase FtsK N-terminal domain › DNA translocase FtsK N-terminal domain | 0.56 | 42.0 | 4.27e-01 | 83.0% | 98.9% |
D9
medium
residues 972-1100
Domain cluster:
rep: KM209246.1__AIM51491.1__HQ82_0234__00002__D56-167
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00521.27 best | DNA_topoisoIV | 42.5 | 5.80e-11 | 93.0% | 26.5% |
CATH (58)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1bgwA03 | 1.10.268.10 | Mainly Alpha › Orthogonal Bundle › Topoisomerase; domain 3 › Topoisomerase, domain 3 | 0.91 | 68.0 | 7.33e-01 | 76.0% | 100.0% |
| 3qx3A04 | 1.10.268.10 | Mainly Alpha › Orthogonal Bundle › Topoisomerase; domain 3 › Topoisomerase, domain 3 | 0.89 | 65.0 | 7.39e-01 | 74.4% | 100.0% |
| 8gccA03 | 1.10.268.10 | Mainly Alpha › Orthogonal Bundle › Topoisomerase; domain 3 › Topoisomerase, domain 3 | 0.88 | 69.0 | 7.73e-01 | 80.6% | 100.0% |
| 1wleA01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.84 | 48.0 | 5.12e-01 | 87.6% | 64.9% |
| 8h6rA01 | 1.20.930.10 | Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 | 0.83 | 30.0 | 3.81e-01 | 75.2% | 54.1% |
| 1oahA02 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.77 | 47.0 | 4.58e-01 | 91.5% | 55.6% |
| 1zvuA03 | 1.10.268.10 | Mainly Alpha › Orthogonal Bundle › Topoisomerase; domain 3 › Topoisomerase, domain 3 | 0.75 | 67.0 | 6.56e-01 | 98.4% | 87.9% |
| 4aflA00 | 6.10.140.1740 | Special › Helix non-globular › Helix Hairpins › | 0.75 | 40.0 | 4.48e-01 | 87.6% | 65.7% |
| 4egwA02 | 1.20.58.340 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region | 0.75 | 40.0 | 4.22e-01 | 88.4% | 56.3% |
| 3hr0B01 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.75 | 45.0 | 5.61e-01 | 89.9% | 97.5% |
| 2p5tA00 | 1.10.8.130 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.74 | 39.0 | 4.63e-01 | 91.5% | 72.8% |
| 2i0mA01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.71 | 39.0 | 4.23e-01 | 88.4% | 64.2% |
| 3agtA00 | 1.20.120.50 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like | 0.70 | 39.0 | 3.91e-01 | 91.5% | 51.9% |
| 4hr1A00 | 1.20.1270.410 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.70 | 41.0 | 4.27e-01 | 87.6% | 63.6% |
| 1sj8A02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.70 | 41.0 | 4.25e-01 | 96.1% | 61.5% |
| 4dylA02 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.69 | 44.0 | 5.13e-01 | 86.8% | 89.4% |
| 2q0oC00 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.68 | 39.0 | 4.76e-01 | 81.4% | 86.0% |
| 1fewA00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.68 | 43.0 | 3.89e-01 | 87.6% | 48.0% |
| 6a3kA00 | 1.20.120.10 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 | 0.66 | 39.0 | 3.98e-01 | 91.5% | 58.1% |
| 3au3A00 | 1.25.10.10 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant | 0.66 | 34.0 | 2.60e-01 | 85.3% | 20.9% |
| 6vudA01 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.65 | 37.0 | 4.03e-01 | 90.7% | 66.1% |
| 4d8mA01 | 1.20.190.10 | Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › Pesticidal crystal protein, N-terminal domain | 0.63 | 45.0 | 3.71e-01 | 89.9% | 43.5% |
| 3ckyA02 | 1.10.1040.10 | Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 | 0.62 | 42.0 | 4.23e-01 | 81.4% | 66.4% |
| 7wu7601 | 1.10.287.370 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.62 | 41.0 | 4.57e-01 | 87.6% | 86.0% |
| 1jmwA00 | 1.20.120.30 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Aspartate receptor, ligand-binding domain | 0.62 | 51.0 | 4.91e-01 | 87.6% | 99.3% |
| 4hz4A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.61 | 34.0 | 3.59e-01 | 79.1% | 59.8% |
| 3fppA03 | 6.10.140.1990 | Special › Helix non-globular › Helix Hairpins › | 0.61 | 39.0 | 4.56e-01 | 88.4% | 94.3% |
| 7aalA01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.60 | 45.0 | 3.44e-01 | 88.4% | 36.8% |
| 3ezhA00 | 1.20.120.960 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Histidine kinase NarX, sensor domain | 0.60 | 44.0 | 4.66e-01 | 76.0% | 100.0% |
| 1hciA04 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.59 | 36.0 | 3.85e-01 | 86.0% | 69.3% |
| 4ys0A02 | 1.10.3060.10 | Mainly Alpha › Orthogonal Bundle › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA | 0.58 | 32.0 | 2.95e-01 | 82.2% | 41.2% |
| 2d4uB00 | 1.20.120.30 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Aspartate receptor, ligand-binding domain | 0.58 | 48.0 | 4.57e-01 | 89.9% | 97.4% |
| 3kkbA00 | 1.20.120.880 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Histidine kinase (KinB), sensor domain | 0.57 | 47.0 | 4.81e-01 | 89.9% | 100.0% |
| 3u0cA00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.57 | 42.0 | 3.98e-01 | 89.9% | 65.6% |
| 1dn1B00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.56 | 46.0 | 3.76e-01 | 86.0% | 51.4% |
| 3i01A01 | 1.20.1270.30 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.56 | 49.0 | 4.35e-01 | 93.8% | 78.5% |
| 1orjD00 | 1.20.120.340 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS | 0.55 | 44.0 | 4.51e-01 | 84.5% | 93.6% |
| 6grjB01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.55 | 41.0 | 3.08e-01 | 76.7% | 90.7% |
| 1jqkA03 | 1.20.1270.30 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.55 | 48.0 | 4.29e-01 | 93.0% | 80.0% |
| 1qoyA00 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.55 | 51.0 | 3.80e-01 | 100.0% | 58.1% |
| 1sziA02 | 1.20.120.340 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS | 0.54 | 45.0 | 4.44e-01 | 89.9% | 96.4% |
| 5llmA00 | 1.10.3860.10 | Mainly Alpha › Orthogonal Bundle › Proton glutamate symport protein › Sodium:dicarboxylate symporter | 0.54 | 42.0 | 3.06e-01 | 85.3% | 41.9% |
| 4iloA00 | 1.10.287.1490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.54 | 45.0 | 3.60e-01 | 87.6% | 64.4% |
| 3vkgA12 | 1.10.287.2610 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.54 | 46.0 | 3.78e-01 | 89.1% | 65.6% |
| 4cgkA01 | 6.10.250.3150 | Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.53 | 44.0 | 3.68e-01 | 87.6% | 52.3% |
| 1wn0A00 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.53 | 41.0 | 4.14e-01 | 83.7% | 80.2% |
| 1f1mA00 | 1.20.120.240 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Lipoprotein, type 6 | 0.53 | 44.0 | 4.14e-01 | 89.9% | 98.8% |
| 1dxrL02 | 1.20.85.10 | Mainly Alpha › Up-down Bundle › Photosynthetic Reaction Center, subunit M; domain 1 › Photosystem II protein D1-like | 0.53 | 34.0 | 3.70e-01 | 89.1% | 76.9% |
| 4dylA01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.53 | 47.0 | 3.76e-01 | 95.3% | 74.0% |
| 3syvA01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.53 | 48.0 | 3.78e-01 | 95.3% | 75.1% |
| 6q45G01 | 1.10.287.80 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain | 0.53 | 45.0 | 4.32e-01 | 89.9% | 83.6% |
| 6h2dS01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.52 | 37.0 | 3.12e-01 | 73.6% | 88.8% |
| 4e40A00 | 1.20.1260.80 | Mainly Alpha › Up-down Bundle › Ferritin › | 0.52 | 46.0 | 3.64e-01 | 93.8% | 73.9% |
| 2oexA02 | 1.20.140.50 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › alix/aip1 like domains | 0.52 | 42.0 | 3.60e-01 | 89.9% | 55.8% |
| 3k29A00 | 1.10.287.1700 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.52 | 41.0 | 3.81e-01 | 89.9% | 67.1% |
| 2nsfA01 | 1.20.120.450 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › dinb family like domain | 0.51 | 39.0 | 3.62e-01 | 78.3% | 76.1% |
| 4mh6A00 | 1.10.287.1700 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.51 | 41.0 | 3.83e-01 | 89.9% | 67.9% |
| 2rfqC03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.51 | 46.0 | 4.15e-01 | 98.4% | 95.4% |
ECOD (73)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3708939 | 4016.1.1.1 ↗ | alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV | 0.96 | 88.0 | 8.19e-01 | 100.0% | 79.4% |
| 3718739 | 4016.1.1.1 ↗ | alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV | 0.95 | 93.0 | 8.33e-01 | 100.0% | 87.9% |
| 3600354 | 4016.1.1.0 ↗ | alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase | 0.95 | 87.0 | 8.20e-01 | 100.0% | 82.0% |
| 3789604 | 4016.1.1.0 ↗ | alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase | 0.94 | 92.0 | 8.60e-01 | 100.0% | 90.7% |
| 3328306 | 4016.1.1.1 ↗ | alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV | 0.94 | 92.0 | 7.81e-01 | 100.0% | 83.2% |
| 3610015 | 4016.1.1.1 ↗ | alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV | 0.94 | 92.0 | 8.26e-01 | 100.0% | 84.2% |
| 3935542 | 4016.1.1.1 ↗ | alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV | 0.94 | 90.0 | 8.46e-01 | 100.0% | 85.3% |
| 3625174 | 4016.1.1.1 ↗ | alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV | 0.94 | 91.0 | 7.44e-01 | 100.0% | 82.4% |
| 3276180 | 4016.1.1.1 ↗ | alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV | 0.94 | 91.0 | 7.66e-01 | 100.0% | 85.1% |
| 3634044 | 4016.1.1.1 ↗ | alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV | 0.94 | 91.0 | 7.73e-01 | 100.0% | 82.1% |
| 3768919 | 4016.1.1.1 ↗ | alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV | 0.93 | 89.0 | 6.52e-01 | 100.0% | 53.0% |
| 4238706 | 101.1.2.9 ↗ | alpha arrays › HTH › HTH › winged helix domain › DNA_topoisoIV | 0.93 | 89.0 | 6.47e-01 | 100.0% | 51.5% |
| 3508111 | 4016.1.1.1 ↗ | alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV | 0.92 | 89.0 | 7.75e-01 | 100.0% | 90.6% |
| 3652359 | 4016.1.1.1 ↗ | alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV | 0.92 | 89.0 | 7.96e-01 | 100.0% | 76.5% |
| 3220667 | 4016.1.1.1 ↗ | alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV | 0.91 | 86.0 | 8.49e-01 | 98.4% | 97.0% |
| 4452951 | 4016.1.1.1 ↗ | alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV | 0.91 | 87.0 | 7.72e-01 | 100.0% | 85.1% |
| 4878008 | 4016.1.1.1 ↗ | alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV | 0.91 | 78.0 | 8.07e-01 | 94.6% | 94.2% |
| 3630114 | 4016.1.1.1 ↗ | alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV | 0.91 | 87.0 | 8.33e-01 | 100.0% | 93.8% |
| 4830953 | 101.1.2.9 ↗ | alpha arrays › HTH › HTH › winged helix domain › DNA_topoisoIV | 0.90 | 85.0 | 7.58e-01 | 100.0% | 78.6% |
| 223696 | 4016.1.1.1 ↗ | alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV | 0.89 | 84.0 | 7.94e-01 | 100.0% | 90.1% |
| 3267708 | 4016.1.1.1 ↗ | alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV | 0.88 | 84.0 | 8.03e-01 | 100.0% | 89.7% |
| 3096549 | 4016.1.1.0 ↗ | alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase | 0.86 | 81.0 | 7.38e-01 | 100.0% | 90.4% |
| 2443871 | 4016.1.1.1 ↗ | alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › DNA_topoisoIV | 0.85 | 81.0 | 7.32e-01 | 100.0% | 89.2% |
| 5083298 | 4016.1.1.0 ↗ | alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase | 0.80 | 75.0 | 7.12e-01 | 99.2% | 85.3% |
| 3833806 | 4016.1.1.0 ↗ | alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase | 0.80 | 65.0 | 6.25e-01 | 86.0% | 75.9% |
| 4570966 | 4016.1.1.0 ↗ | alpha bundles › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase › alpha-helical domain in type II DNA topoisomerase | 0.79 | 74.0 | 7.01e-01 | 100.0% | 88.0% |
| 3228170 | 192.8.1.0 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain | 0.70 | 58.0 | 5.56e-01 | 86.8% | 100.0% |
| 3662019 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.69 | 50.0 | 4.76e-01 | 95.3% | 64.8% |
| 3552989 | 604.8.1.1 ↗ | alpha bundles › Spectrin repeat-like › Smac/diablo › Smac/diablo › Smac_DIABLO | 0.69 | 45.0 | 3.90e-01 | 88.4% | 45.7% |
| 4980166 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.69 | 43.0 | 3.88e-01 | 88.4% | 46.5% |
| 3617266 | 632.1.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain | 0.69 | 46.0 | 4.76e-01 | 93.8% | 72.5% |
| 3714236 | 632.7.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.67 | 39.0 | 3.97e-01 | 93.8% | 56.9% |
| 3589719 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.67 | 42.0 | 3.62e-01 | 89.1% | 41.5% |
| 4946656 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.66 | 44.0 | 4.55e-01 | 89.9% | 71.7% |
| 3738267 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.65 | 41.0 | 3.85e-01 | 87.6% | 54.0% |
| 3688466 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.65 | 47.0 | 4.30e-01 | 87.6% | 59.4% |
| 3295653 | 4268.2.1.0 ↗ | alpha duplicates or obligate multimers › EspA/CesA-like › EspA chaperone CesA › EspA chaperone CesA | 0.65 | 37.0 | 3.85e-01 | 86.8% | 60.0% |
| 3838012 | 601.1.2.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) | 0.64 | 44.0 | 4.55e-01 | 93.0% | 73.6% |
| 5005708 | 3755.3.1.127 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › NFACT_N | 0.63 | 50.0 | 4.43e-01 | 89.1% | 58.9% |
| 3305747 | 192.2.1.18 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › ING | 0.63 | 46.0 | 4.50e-01 | 88.4% | 69.3% |
| 3917933 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.62 | 52.0 | 5.09e-01 | 87.6% | 85.7% |
| 3172861 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.62 | 44.0 | 3.98e-01 | 89.9% | 54.7% |
| 3273799 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.62 | 53.0 | 4.18e-01 | 89.9% | 100.0% |
| 3173337 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.61 | 45.0 | 3.38e-01 | 76.0% | 98.7% |
| 4999448 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.60 | 50.0 | 3.95e-01 | 86.8% | 48.2% |
| 3701475 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.60 | 46.0 | 4.44e-01 | 89.1% | 71.7% |
| 4057653 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.60 | 50.0 | 3.87e-01 | 89.9% | 41.8% |
| 3875142 | 601.11.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Mannose-6-phosphate receptor binding protein 1 (Tip47), C-terminal domain › Mannose-6-phosphate receptor binding protein 1 (Tip47), C-terminal domain › Perilipin | 0.59 | 51.0 | 4.17e-01 | 92.2% | 72.6% |
| 4063163 | 3755.1.1.0 ↗ | alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related | 0.59 | 44.0 | 3.98e-01 | 88.4% | 57.7% |
| 4549103 | 3755.4.1.54 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › PF30340 | 0.58 | 46.0 | 3.24e-01 | 83.7% | 100.0% |
| 4959549 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.58 | 49.0 | 4.30e-01 | 89.9% | 74.1% |
| 3860568 | 150.1.1.80 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Myelin_PLP | 0.57 | 45.0 | 3.85e-01 | 88.4% | 52.7% |
| 3235363 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.56 | 47.0 | 3.87e-01 | 87.6% | 59.5% |
| 4955963 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.56 | 44.0 | 3.75e-01 | 89.9% | 52.5% |
| 3497316 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.56 | 47.0 | 4.33e-01 | 87.6% | 80.6% |
| 4946568 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.56 | 47.0 | 2.89e-01 | 87.6% | 31.1% |
| 3594019 | 192.8.1.0 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain | 0.55 | 48.0 | 3.64e-01 | 89.1% | 46.0% |
| 3309007 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.55 | 47.0 | 4.03e-01 | 89.1% | 66.7% |
| 3715936 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.55 | 47.0 | 4.21e-01 | 89.9% | 66.3% |
| 3579748 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.55 | 50.0 | 4.51e-01 | 96.1% | 88.2% |
| 3412891 | 150.1.1.31 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Tweety | 0.54 | 45.0 | 3.47e-01 | 87.6% | 62.2% |
| 3397986 | 3755.4.1.1 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › PI3K_P85_iSH2 | 0.54 | 43.0 | 3.80e-01 | 88.4% | 59.4% |
| 4006117 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.54 | 45.0 | 3.78e-01 | 87.6% | 53.8% |
| 4027809 | 3871.1.1.0 ↗ | alpha duplicates or obligate multimers › PHIST › PHIST › PHIST | 0.54 | 37.0 | 3.60e-01 | 94.6% | 62.8% |
| 4652027 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.54 | 44.0 | 4.28e-01 | 89.9% | 77.2% |
| 5006400 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.54 | 44.0 | 3.57e-01 | 87.6% | 48.3% |
| 3538350 | 3755.1.1.0 ↗ | alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related | 0.53 | 45.0 | 4.47e-01 | 88.4% | 86.7% |
| 4683246 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.53 | 45.0 | 3.93e-01 | 87.6% | 71.1% |
| 3470807 | 3755.3.1.49 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › GPHR_N | 0.53 | 48.0 | 4.02e-01 | 94.6% | 89.5% |
| 5036055 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.53 | 44.0 | 3.16e-01 | 87.6% | 99.1% |
| 3717131 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.51 | 44.0 | 3.83e-01 | 89.9% | 62.7% |
| 3650111 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.51 | 42.0 | 2.98e-01 | 87.6% | 100.0% |
| 3885676 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.50 | 40.0 | 3.48e-01 | 86.8% | 56.8% |