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putative_DNA_topoisomerase_II

Euk-Vir

Heterosigma_akashiwo_virus_01

putative_DNA_topoisomerase_II__YP_009507473__Heterosigma_akashiwo_virus_01__97195

Identity

Accession:: YP_009507473 ↗
Protein ID:: putative_DNA_topoisomerase_II
Kingdom:: euk

Quality

85.1 mean pLDDT

Taxonomy

Bamfordvirae› Nucleocytoviricota› Megaviricetes› Algavirales› Phycodnaviridae› Raphidovirus› Heterosigma_akashiwo_virus_01

TaxID: 97195

Cluster

View cluster (39 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 51-122_134-241

PDB

Domain cluster: rep: IMGVR_UViG_3300039190_000305-3300039190-Ga0399989_003201_3_1937__D82-97_167-336

D2 high residues 858-949

PDB

Domain cluster: rep: IMGVR_UViG_3300007985_000017-3300007985-Ga0100381_100027569__D212-299

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF00521.27 best	DNA_topoisoIV	31.5	1.30e-07	96.7%	19.0%

D3 high residues 977-1085

PDB

Domain cluster: rep: KM209246.1__AIM51491.1__HQ82_0234__00002__D56-167

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF00521.27 best	DNA_topoisoIV	34.7	1.30e-08	100.0%	26.5%

D4 medium residues 242-398

PDB

Domain cluster: rep: DNA_gyrase_subunit_B__YP_009352802__Kaumoebavirus_Viruses.__X__D311-415

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF00204.32 best	DNA_gyraseB	66.2	3.60e-18	94.9%	58.1%

D5 medium residues 399-524

PDB

Domain cluster: rep: term2_saliva_scaffold_1_prodigal-single.1__X__X__00117__D395-534_709-736

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF01751.29 best	Toprim	40.8	2.80e-10	83.3%	84.4%

D6 medium residues 525-605

PDB

Domain cluster: rep: DNA_topoisomerase_II__YP_009506801__Tunisvirus_fontaine2__1421067__D565-621

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF16898.11 best	TOPRIM_C	70.7	1.90e-19	93.8%	48.4%

CATH (4)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
2xcqA01	3.40.50.670	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold ›	0.68	57.0	4.29e-01	90.1%	39.9%
1r9wA00	3.40.1310.10	Alpha Beta › 3-Layer(aba) Sandwich › Replication Protein E1; Chain: A, ›	0.59	42.0	3.59e-01	75.3%	74.6%
3tiiA03	3.30.1490.20	Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › ATP-grasp fold, A domain	0.59	32.0	3.50e-01	71.6%	63.1%
1f08B00	3.40.1310.10	Alpha Beta › 3-Layer(aba) Sandwich › Replication Protein E1; Chain: A, ›	0.57	40.0	3.42e-01	75.3%	71.0%

ECOD (16)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3551383	2006.1.3.3 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › Toprim,TOPRIM_C	0.91	87.0	5.66e-01	100.0%	39.0%
3213306	2006.1.3.21 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › TOPRIM_C	0.90	86.0	5.72e-01	100.0%	31.1%
3789608	2006.1.3.0 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain	0.88	83.0	5.53e-01	100.0%	41.1%
4878011	2006.1.3.21 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › TOPRIM_C	0.85	77.0	5.50e-01	100.0%	36.6%
4878090	4012.1.1.1 ↗	a+b two layers › SSHS domain › SSHS domain in type II DNA topoisomerase › SSHS domain in type II DNA topoisomerase › TOPRIM_C	0.82	75.0	6.52e-01	100.0%	68.1%
3964707	2006.1.3.0 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain	0.81	74.0	5.25e-01	100.0%	38.7%
4124102	2006.1.3.0 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain	0.78	72.0	5.03e-01	100.0%	37.5%
3164150	2006.1.3.1 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › DNA_gyraseB_C,Toprim	0.77	70.0	5.00e-01	100.0%	40.4%
None	—		0.76	70.0	4.92e-01	100.0%	35.6%
4100838	2006.1.3.1 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › DNA_gyraseB_C,Toprim	0.76	71.0	5.03e-01	100.0%	37.1%
4406660	2006.1.3.1 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › DNA_gyraseB_C,Toprim	0.74	68.0	4.77e-01	100.0%	36.3%
3520955	2006.1.3.1 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › DNA_gyraseB_C,Toprim	0.73	67.0	4.60e-01	100.0%	33.6%
4238497	2006.1.3.1 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › Toprim domain › DNA_gyraseB_C,Toprim	0.73	66.0	4.72e-01	100.0%	43.9%
5076740	304.4.1.0 ↗	a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel	0.54	41.0	3.86e-01	85.2%	81.0%
4488855	275.1.1.5 ↗	a+b two layers › MoeA-I/Ornithine decarboxylase-C/Reverse ferredoxin-like domain in RNA-polymerase › MoeA-I/Ornithine decarboxylase-C/Reverse ferredoxin-like domain in RNA-polymerase › MoeA-I/Ornithine decarboxylase-C/Reverse ferredoxin-like domain in RNA-polymerase › Arc_PepC	0.51	38.0	3.79e-01	81.5%	95.3%
5066389	69.1.1.4 ↗	beta complex topology › Hedgehog/intein › Hedgehog/intein › Hint › Intein_splicing	0.50	35.0	2.72e-01	72.8%	91.6%

D7 medium residues 606-679

PDB

Domain cluster: rep: DNA_topoisomerase_II__YP_009238657__Brazilian_marseillevirus__1813599__D609-672

D8 medium residues 680-789

PDB

Domain cluster: rep: DNA_topoisomerase_2__YP_009162467__Salmon_gill_poxvirus__1680908__D669-796

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF00521.27 best	DNA_topoisoIV	119.7	2.20e-34	100.0%	24.6%

D9 medium residues 790-845

PDB

Domain cluster: representative

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF00521.27 best	DNA_topoisoIV	64.2	1.60e-17	100.0%	12.8%

CATH (3)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
1bjtA05	3.90.199.10	Alpha Beta › Alpha-Beta Complex › Topoisomerase II; domain 5 › Topoisomerase II, domain 5	0.96	91.0	5.68e-01	100.0%	22.5%
1kkmB00	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.51	35.0	2.50e-01	73.2%	83.6%
4ac9C01	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.50	38.0	2.72e-01	83.9%	60.1%

ECOD (18)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3719735	4014.1.1.1 ↗	a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV	1.00	69.0	4.68e-01	71.4%	24.2%
3188905	4014.1.1.1 ↗	a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV	0.99	68.0	4.54e-01	71.4%	26.7%
3277529	4014.1.1.1 ↗	a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV	0.98	67.0	4.62e-01	71.4%	25.0%
3998667	4014.1.1.1 ↗	a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV	0.97	70.0	4.59e-01	75.0%	21.5%
3220665	4014.1.1.1 ↗	a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV	0.96	71.0	4.77e-01	76.8%	24.6%
2390536	4014.1.1.1 ↗	a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV	0.96	90.0	6.21e-01	100.0%	34.6%
3789606	4014.1.1.0 ↗	a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase	0.96	70.0	4.78e-01	76.8%	25.3%
4266765	4014.1.1.1 ↗	a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV	0.95	71.0	4.89e-01	78.6%	26.7%
3594650	4014.1.1.0 ↗	a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase	0.95	65.0	4.50e-01	71.4%	26.9%
3614277	4014.1.1.1 ↗	a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV	0.94	66.0	4.44e-01	73.2%	24.4%
4024263	4014.1.1.1 ↗	a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV	0.92	67.0	4.35e-01	76.8%	22.3%
4946212	4014.1.1.1 ↗	a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV	0.91	63.0	4.21e-01	71.4%	24.3%
3962339	4014.1.1.0 ↗	a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase	0.91	64.0	4.26e-01	73.2%	27.0%
3965475	4014.1.1.1 ↗	a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV	0.89	64.0	4.19e-01	75.0%	22.9%
3590557	4014.1.1.1 ↗	a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV	0.89	64.0	4.22e-01	75.0%	24.1%
4624017	4014.1.1.1 ↗	a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV	0.88	66.0	4.46e-01	78.6%	27.2%
396210	4014.1.1.1 ↗	a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV	0.86	78.0	5.02e-01	100.0%	27.5%
2140592	4014.1.1.1 ↗	a+b two layers › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › a+b domain in type II DNA topoisomerase › DNA_topoisoIV	0.79	58.0	3.92e-01	76.8%	26.4%