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putative_H4L_protein

Euk-Vir

Orthopoxvirus_Abatino

putative_H4L_protein__YP_010085770__Orthopoxvirus_Abatino__2478919

Identity

Accession:: YP_010085770 ↗
Protein ID:: putative_H4L_protein
Kingdom:: euk

Quality

65.4 mean pLDDT

Taxonomy

Bamfordvirae› Nucleocytoviricota› Pokkesviricetes› Chitovirales› Poxviridae› Orthopoxvirus› Orthopoxvirus_Abatino

TaxID: 2478919

Cluster

View cluster (28 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 4-96

PDB

D2 high residues 329-377

PDB

Domain cluster: representative

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF03294.20 best	Pox_Rap94	76.5	2.00e-21	100.0%	6.2%

CATH (24)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
1ed1A00	1.10.150.90	Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Immunodeficiency lentiviruses, gag gene matrix protein p17	0.68	49.0	3.67e-01	75.5%	53.5%
1xocA03	3.10.105.10	Alpha Beta › Roll › Dipeptide-binding Protein; domain 3 › Dipeptide-binding Protein; Domain 3	0.63	50.0	3.34e-01	95.9%	50.9%
3m7nA03	2.20.70.10	Mainly Beta › Single Sheet › Ubiquitin Ligase Nedd4; Chain: W; ›	0.62	37.0	4.10e-01	98.0%	79.4%
3lvuB00	3.10.105.10	Alpha Beta › Roll › Dipeptide-binding Protein; domain 3 › Dipeptide-binding Protein; Domain 3	0.61	49.0	3.22e-01	100.0%	56.0%
3draB00	1.50.10.20	Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase ›	0.60	50.0	3.08e-01	100.0%	91.8%
6wm6A01	3.10.105.10	Alpha Beta › Roll › Dipeptide-binding Protein; domain 3 › Dipeptide-binding Protein; Domain 3	0.60	49.0	3.27e-01	100.0%	50.9%
3pamB00	3.10.105.10	Alpha Beta › Roll › Dipeptide-binding Protein; domain 3 › Dipeptide-binding Protein; Domain 3	0.60	46.0	3.05e-01	95.9%	53.6%
3etvA02	1.20.58.2230	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Retrograde transport protein Dsl1, N-terminal domain	0.58	50.0	3.28e-01	100.0%	49.8%
2y8nB01	2.20.70.100	Mainly Beta › Single Sheet › Ubiquitin Ligase Nedd4; Chain: W; ›	0.58	35.0	3.78e-01	79.6%	69.0%
7atrA01	3.10.105.10	Alpha Beta › Roll › Dipeptide-binding Protein; domain 3 › Dipeptide-binding Protein; Domain 3	0.58	49.0	3.18e-01	100.0%	57.1%
3u50C02	2.20.25.10	Mainly Beta › Single Sheet › N-terminal domain of TfIIb ›	0.58	33.0	3.66e-01	91.8%	71.4%
6s2vC02	3.30.460.10	Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Beta Polymerase, domain 2	0.58	44.0	3.33e-01	91.8%	82.8%
2aklA01	2.20.25.10	Mainly Beta › Single Sheet › N-terminal domain of TfIIb ›	0.57	34.0	3.60e-01	93.9%	62.8%
1k38A00	3.40.710.10	Alpha Beta › 3-Layer(aba) Sandwich › Beta-lactamase › DD-peptidase/beta-lactamase superfamily	0.55	41.0	2.82e-01	91.8%	24.7%
6edhA00	3.60.130.10	Alpha Beta › 4-Layer Sandwich › Double-stranded beta-helix › Clavaminate synthase-like	0.55	46.0	2.97e-01	100.0%	94.3%
1ekgA00	3.30.920.10	Alpha Beta › 2-Layer Sandwich › Metal Transport, Frataxin; Chain A › Frataxin/CyaY	0.54	40.0	3.16e-01	85.7%	79.8%
3gmiA02	3.40.50.620	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs	0.53	39.0	2.55e-01	79.6%	55.3%
1hfxA00	1.10.530.10	Mainly Alpha › Orthogonal Bundle › Lysozyme ›	0.53	41.0	3.17e-01	85.7%	56.9%
4i8oA04	6.10.250.2650	Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces ›	0.52	44.0	3.61e-01	100.0%	54.1%
2g0qA01	3.10.490.10	Alpha Beta › Roll › Hypothetical upf0131 protein ytfp › Gamma-glutamyl cyclotransferase-like	0.52	43.0	3.39e-01	98.0%	93.9%
1vj7B02	3.30.460.10	Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Beta Polymerase, domain 2	0.52	40.0	3.28e-01	100.0%	85.7%
2nutB02	2.30.30.380	Mainly Beta › Roll › SH3 type barrels. › Zn-finger domain of Sec23/24	0.51	36.0	3.43e-01	75.5%	66.1%
2gzaA01	3.30.450.90	Alpha Beta › 2-Layer Sandwich › Beta-Lactamase ›	0.51	42.0	3.41e-01	98.0%	87.0%
2yyzA02	2.40.50.100	Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › RNA polymerase II/Efflux pump adaptor protein, barrel-sandwich hybrid domain	0.51	33.0	3.17e-01	95.9%	53.4%

ECOD (34)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3484622	386.1.1.1 ↗	few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › zf-C2H2	0.79	56.0	4.73e-01	83.7%	46.3%
3216512	386.1.1.0 ↗	few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers	0.65	47.0	4.09e-01	79.6%	86.3%
3623330	386.1.1.24 ↗	few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › zf-C2H2_4	0.64	47.0	4.54e-01	83.7%	73.3%
3579412	386.1.1.0 ↗	few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers	0.64	51.0	4.72e-01	89.8%	72.3%
5034935	243.6.1.9 ↗	a+b two layers › Cystatin-like › Pre-PUA domain › Pre-PUA domain › TGT_C2	0.64	44.0	3.94e-01	73.5%	60.0%
3948214	7523.1.1.3 ↗	a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II › SBP_bac_5	0.63	49.0	3.19e-01	93.9%	54.2%
3844188	386.1.1.289 ↗	few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › PF30903	0.61	42.0	4.00e-01	73.5%	63.3%
4480144	129.1.1.2 ↗	alpha arrays › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › 3HCDH	0.61	51.0	3.83e-01	100.0%	62.2%
3765582	386.1.1.289 ↗	few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › PF30903	0.61	41.0	3.58e-01	71.4%	43.8%
2774848	7523.1.1.3 ↗	a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II › SBP_bac_5	0.60	49.0	3.27e-01	100.0%	51.1%
5050250	375.1.1.0 ↗	few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related	0.60	36.0	3.98e-01	98.0%	77.1%
4846382	304.136.1.1 ↗	a+b two layers › Alpha-beta plaits › Oligo-peptide binding protein (OPPA) insertion domain › Oligo-peptide binding protein (OPPA) insertion domain › SBP_bac_5	0.58	48.0	3.15e-01	100.0%	55.6%
3346948	4958.1.1.2 ↗	a+b complex topology › second helical domain in RNA-polymerase beta-prime subunit › second helical domain in RNA-polymerase beta-prime subunit › second helical domain in RNA-polymerase beta-prime subunit › RNA_pol_Rpb1_4	0.58	41.0	2.64e-01	77.6%	15.2%
4934110	375.1.1.0 ↗	few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related	0.57	39.0	3.50e-01	71.4%	51.4%
4230570	7523.1.1.3 ↗	a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II › SBP_bac_5	0.57	46.0	2.99e-01	93.9%	55.5%
5060162	66.1.1.4 ↗	beta sandwiches › ISP domain › ISP domain › ISP domain › FtrD-like	0.56	40.0	3.05e-01	77.6%	59.7%
3236762	386.1.1.0 ↗	few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers	0.56	43.0	3.83e-01	89.8%	61.3%
4989659	2484.1.1.302 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB	0.56	39.0	2.98e-01	77.6%	75.4%
3741416	375.1.1.42 ↗	few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › Rep_fac-A_C	0.55	34.0	3.63e-01	91.8%	90.0%
3275056	109.3.1.0 ↗	alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat	0.55	46.0	3.15e-01	100.0%	43.6%
3835577	4958.1.1.0 ↗	a+b complex topology › second helical domain in RNA-polymerase beta-prime subunit › second helical domain in RNA-polymerase beta-prime subunit › second helical domain in RNA-polymerase beta-prime subunit	0.55	45.0	3.09e-01	100.0%	61.5%
4990476	386.1.1.24 ↗	few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › zf-C2H2_4	0.55	45.0	3.83e-01	93.9%	72.9%
3742452	109.4.1.0 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat	0.55	44.0	2.79e-01	100.0%	58.8%
3971903	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.54	44.0	3.05e-01	91.8%	73.7%
4014848	226.1.1.0 ↗	a+b two layers › POZ domain › POZ domain › POZ domain	0.53	41.0	2.81e-01	89.8%	23.1%
4646065	102.8.1.0 ↗	alpha arrays › HhH/H2TH › UPF0348 protein MJ0951 C-terminal domain › UPF0348 protein MJ0951 C-terminal domain	0.53	38.0	2.44e-01	77.6%	46.9%
4163716	386.1.1.6 ↗	few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › ARS2	0.53	35.0	3.48e-01	71.4%	67.3%
5011867	2484.1.1.302 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB	0.53	44.0	3.08e-01	98.0%	39.9%
2881503	1189.1.1.2 ↗	alpha bundles › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG_B	0.52	42.0	2.64e-01	100.0%	83.9%
3446330	176.1.1.0 ↗	alpha arrays › Annexin › Annexin › Annexin	0.52	40.0	3.34e-01	83.7%	72.9%
3314730	375.1.1.13 ↗	few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › Ribosomal_L37ae	0.51	39.0	3.72e-01	89.8%	70.0%
5055179	2484.1.1.302 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB	0.51	42.0	2.81e-01	95.9%	41.4%
5013223	2484.1.1.302 ↗	mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB	0.51	41.0	2.82e-01	95.9%	55.6%
3786278	2011.2.1.3 ↗	a/b three-layered sandwiches › Phosphorylase/hydrolase-like › Peptidyl-tRNA hydrolase-like › Peptidyl-tRNA hydrolase-like › Pept_tRNA_hydro	0.50	40.0	2.74e-01	91.8%	36.8%

D3 medium residues 117-132_155-285

PDB

D4 medium residues 391-495

PDB

D5 medium residues 496-584

PDB

Domain cluster: representative

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF03294.20 best	Pox_Rap94	135.9	2.10e-39	100.0%	11.2%

CATH (17)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
2pmrA00	1.20.1270.90	Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › AF1782-like	0.75	38.0	4.17e-01	85.4%	59.2%
6jrpA01	1.10.30.10	Mainly Alpha › Orthogonal Bundle › DNA Binding (I), subunit A › High mobility group box domain	0.69	46.0	5.32e-01	74.2%	100.0%
4gpkB01	1.25.40.1000	Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat ›	0.66	41.0	3.98e-01	96.6%	55.6%
4hteA01	1.20.58.1730	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.64	46.0	3.96e-01	75.3%	79.0%
4gczA03	1.10.287.130	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain	0.63	36.0	4.21e-01	85.4%	78.5%
2q0oC00	1.10.287.160	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat	0.62	35.0	3.63e-01	85.4%	58.1%
2yf4F00	1.10.3420.10	Mainly Alpha › Orthogonal Bundle › putative ntp pyrophosphohydrolase like fold › putative ntp pyrophosphohydrolase like domain	0.62	34.0	2.93e-01	70.8%	33.6%
1y6xA00	1.10.287.1080	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like	0.59	36.0	3.72e-01	89.9%	63.2%
1wteB01	1.10.3250.10	Mainly Alpha › Orthogonal Bundle › type ii restriction endonuclease, domain 1 › type ii restriction endonuclease, domain 1	0.58	53.0	4.46e-01	100.0%	84.4%
2h7oA01	1.20.120.1330	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Rac1-binding domain, N-terminal GTPase binding subdomain	0.57	42.0	3.80e-01	100.0%	56.1%
3fd9A03	1.10.287.1060	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like	0.57	35.0	3.84e-01	86.5%	75.3%
1rz4A01	1.25.40.250	Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › ARM repeat; domain 1	0.56	34.0	3.14e-01	98.9%	44.2%
3vw7A01	1.20.1070.10	Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins	0.54	42.0	3.00e-01	83.1%	87.9%
1ivhA03	1.20.140.10	Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3	0.53	34.0	2.92e-01	86.5%	41.1%
4ys0A02	1.10.3060.10	Mainly Alpha › Orthogonal Bundle › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA	0.52	36.0	3.01e-01	73.0%	58.2%
2a6hF01	1.20.120.1810	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) ›	0.50	41.0	3.30e-01	100.0%	43.7%
1hp8A00	1.10.287.1130	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › CytochromE C oxidase copper chaperone	0.50	28.0	3.08e-01	86.5%	67.6%

ECOD (20)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
5035839	632.11.1.0 ↗	alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like	0.70	39.0	4.24e-01	86.5%	65.3%
5035838	632.22.1.0 ↗	alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats	0.65	38.0	3.86e-01	85.4%	57.8%
3269094	1134.1.1.0 ↗	alpha bundles › C-terminal helical domain of alanine-tRNA ligase › C-terminal helical domain of alanine-tRNA ligase › Eukaryotic C-Ala helical domain	0.61	39.0	4.63e-01	100.0%	96.7%
3477418	4992.1.1.12 ↗	extended segments › RelB-like › RelB-like › RelB-like › LIN9_C	0.61	36.0	3.56e-01	89.9%	54.7%
4026417	5041.1.1.1 ↗	extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › ATP-synt_C	0.61	35.0	3.79e-01	82.0%	68.0%
3475614	186.2.1.1 ↗	alpha arrays › lambda integrase-N-like › VEFS domain › VEFS domain › VEFS-Box	0.58	37.0	3.33e-01	95.5%	44.6%
4983374	1075.1.2.0 ↗	alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain	0.58	40.0	3.53e-01	79.8%	48.5%
4493879	4992.1.1.23 ↗	extended segments › RelB-like › RelB-like › RelB-like › Seryl_tRNA_N	0.57	35.0	3.28e-01	89.9%	49.1%
4975581	4163.1.1.1 ↗	alpha bundles › GINS helical bundle-like › GINS helical bundle-like › PSF1 N-terminal domain-like › Sld5	0.56	41.0	3.84e-01	96.6%	61.8%
3971032	1051.1.1.1 ↗	alpha superhelices › Putative 3-oxoacyl-(acyl-carrier-protein) synthase N-terminal domain › Putative 3-oxoacyl-(acyl-carrier-protein) synthase N-terminal domain › Putative 3-oxoacyl-(acyl-carrier-protein) synthase N-terminal domain › HOASN	0.56	38.0	3.86e-01	98.9%	67.8%
4996707	604.1.1.0 ↗	alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat	0.56	43.0	4.55e-01	100.0%	92.5%
3542152	397.7.1.7 ↗	few secondary structure elements › Toxic hairpin › Ribosome-inactivating protein luffin P1 › Ribosome-inactivating protein luffin P1 › BSMAP	0.56	39.0	3.91e-01	98.9%	72.2%
3475712	1134.1.1.0 ↗	alpha bundles › C-terminal helical domain of alanine-tRNA ligase › C-terminal helical domain of alanine-tRNA ligase › Eukaryotic C-Ala helical domain	0.55	38.0	4.12e-01	100.0%	91.4%
None	—		0.55	38.0	2.80e-01	93.3%	26.5%
4608312	2003.1.1.0 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains	0.53	38.0	2.86e-01	76.4%	60.0%
3493358	192.2.1.0 ↗	alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin	0.53	35.0	3.51e-01	86.5%	65.6%
3706842	109.4.1.0 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat	0.53	42.0	2.92e-01	100.0%	25.2%
5065106	7000.1.1.1 ↗	alpha arrays › inserted region in the C-terminal domain of the archeal LeuRS › inserted region in the C-terminal domain of the archeal LeuRS › inserted region in the C-terminal domain of the archeal LeuRS › HTH_OrfB_IS605	0.52	38.0	3.94e-01	95.5%	86.3%
4011010	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.52	41.0	3.55e-01	88.8%	59.3%
5044635	2.21.1.3 ↗	beta barrels › OB-fold › Small protein B (SmpB) › Small protein B (SmpB) › HTH_OrfB_IS605	0.51	37.0	3.12e-01	98.9%	41.1%

D6 medium residues 639-794

PDB

Domain cluster: rep: RAP94_RNA_pol_assoc_protein__YP_008004477__Choristoneura_rosaceana_entomopoxvirus_L__1293539__D643-819

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF03294.20 best	Pox_Rap94	251.1	3.30e-74	100.0%	19.5%