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putative_HD_domain-containing_protein
Euk-VirAcanthamoeba_polyphaga_mimivirus
putative_HD_domain-containing_protein__YP_003986898__Acanthamoeba_polyphaga_mimivirus__212035
Identity
- Accession:
- YP_003986898 ↗
- Protein ID:
- putative_HD_domain-containing_protein
- Kingdom:
- euk
Quality
70.7
mean pLDDT
Taxonomy
Bamfordvirae›
Nucleocytoviricota›
Megaviricetes›
Imitervirales›
Mimiviridae›
Mimivirus›
Acanthamoeba_polyphaga_mimivirus
TaxID: 212035
Cluster
View cluster (3 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 266-342
Domain cluster:
representative
CATH (24)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4it4A02 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.67 | 41.0 | 3.90e-01 | 100.0% | 52.7% |
| 4nq0A00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.60 | 45.0 | 3.17e-01 | 80.5% | 58.7% |
| 1wcrA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.60 | 45.0 | 4.03e-01 | 100.0% | 58.3% |
| 3mekA04 | 1.25.40.970 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.60 | 43.0 | 4.28e-01 | 81.8% | 71.2% |
| 3l1nA01 | 6.10.140.790 | Special › Helix non-globular › Helix Hairpins › | 0.59 | 38.0 | 4.50e-01 | 100.0% | 100.0% |
| 3apzA00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.58 | 51.0 | 3.45e-01 | 98.7% | 89.6% |
| 3rjvA02 | 1.25.40.740 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.58 | 35.0 | 3.78e-01 | 75.3% | 71.9% |
| 4hr1A00 | 1.20.1270.410 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.56 | 38.0 | 3.31e-01 | 100.0% | 45.8% |
| 3ajfA00 | 1.20.1440.190 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Tenuivirus movement protein | 0.56 | 46.0 | 4.41e-01 | 92.2% | 87.0% |
| 4h33A00 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.55 | 50.0 | 4.74e-01 | 100.0% | 84.6% |
| 3rguB00 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.55 | 36.0 | 3.50e-01 | 100.0% | 58.6% |
| 2icwG02 | 1.10.10.530 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › mam-mhc complex, Chain D, Domain 2 | 0.55 | 34.0 | 3.32e-01 | 100.0% | 53.9% |
| 2p4vA01 | 1.10.287.180 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Transcription elongation factor, GreA/GreB, N-terminal domain | 0.54 | 37.0 | 3.76e-01 | 100.0% | 71.1% |
| 2e5zA01 | 1.10.10.790 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Surp module | 0.54 | 38.0 | 4.32e-01 | 80.5% | 98.3% |
| 3gzfD00 | 1.10.150.420 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Coronavirus nonstructural protein 4 C-terminus | 0.53 | 36.0 | 3.40e-01 | 97.4% | 58.2% |
| 1yozA00 | 1.10.3200.10 | Mainly Alpha › Orthogonal Bundle › Hypothetical protein af0941 › AF0941-like | 0.53 | 39.0 | 3.45e-01 | 79.2% | 88.5% |
| 2ra1A03 | 1.20.58.770 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.52 | 37.0 | 4.03e-01 | 79.2% | 92.1% |
| 2qksA01 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.51 | 43.0 | 3.96e-01 | 100.0% | 69.8% |
| 2mjfB00 | 1.20.1440.260 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.51 | 43.0 | 4.12e-01 | 98.7% | 93.7% |
| 3nvoB02 | 1.20.58.340 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region | 0.51 | 38.0 | 3.35e-01 | 80.5% | 80.2% |
| 3nv6A00 | 1.10.630.10 | Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 | 0.51 | 43.0 | 2.78e-01 | 98.7% | 65.1% |
| 2bskB00 | 1.10.287.810 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Mitochondrial import inner membrane translocase subunit tim13 like domains | 0.50 | 33.0 | 3.49e-01 | 96.1% | 76.9% |
| 4oe8C00 | 1.10.8.1170 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.50 | 37.0 | 3.59e-01 | 93.5% | 69.0% |
| 4modA00 | 1.20.5.300 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.50 | 43.0 | 4.38e-01 | 100.0% | 92.1% |
ECOD (29)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3578225 | 632.23.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Helical linker domain in nicking endonuclease N.BspD6I › Helical linker domain in nicking endonuclease N.BspD6I | 0.71 | 40.0 | 4.07e-01 | 98.7% | 57.3% |
| 4993513 | 601.7.1.2 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HEPN | 0.70 | 42.0 | 3.56e-01 | 100.0% | 38.3% |
| 4203130 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.69 | 45.0 | 3.95e-01 | 100.0% | 45.2% |
| 4031946 | 5054.1.1.0 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels | 0.66 | 58.0 | 5.27e-01 | 100.0% | 74.0% |
| 3926402 | 639.2.1.0 ↗ | alpha arrays › HHA-like › Regulator of acid resistance influenced by indole (AriR) › Regulator of acid resistance influenced by indole (AriR) | 0.62 | 53.0 | 5.27e-01 | 93.5% | 91.3% |
| 3743121 | 109.4.1.80 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › RRN3 | 0.62 | 42.0 | 3.05e-01 | 70.1% | 55.1% |
| 3484553 | 5054.1.1.1 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Lig_chan | 0.60 | 47.0 | 3.93e-01 | 100.0% | 47.1% |
| 4955489 | 3922.1.1.359 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › PF27273 | 0.59 | 44.0 | 4.27e-01 | 100.0% | 70.0% |
| 3923557 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.58 | 44.0 | 3.18e-01 | 100.0% | 30.5% |
| 3933421 | 4967.1.1.0 ↗ | alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases | 0.57 | 34.0 | 3.53e-01 | 96.1% | 61.3% |
| 5042372 | 5054.1.1.8 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans_2 | 0.56 | 48.0 | 4.41e-01 | 100.0% | 71.2% |
| 3242683 | 632.1.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain | 0.55 | 38.0 | 3.62e-01 | 100.0% | 61.1% |
| 3602776 | 605.6.1.12 ↗ | alpha duplicates or obligate multimers › ROP-like › HP1531-like › HP1531-like › PF27273 | 0.55 | 47.0 | 4.63e-01 | 100.0% | 87.5% |
| 3483899 | 5081.1.1.1 ↗ | alpha bundles › Rhomboid-like › Rhomboid-like › Rhomboid-like › Rhomboid | 0.55 | 46.0 | 4.06e-01 | 100.0% | 93.6% |
| 353472 | 5054.1.1.8 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans_2 | 0.54 | 46.0 | 4.08e-01 | 100.0% | 65.2% |
| 3628125 | 632.15.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Staphylococcal complement inhibitor (SCIN) › Staphylococcal complement inhibitor (SCIN) | 0.53 | 37.0 | 3.80e-01 | 72.7% | 98.7% |
| 3564428 | 5054.1.1.59 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans, Ion_trans_2 | 0.53 | 46.0 | 3.10e-01 | 100.0% | 23.9% |
| 3251160 | 5054.1.1.6 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › TrkH | 0.53 | 47.0 | 4.31e-01 | 100.0% | 76.0% |
| 4974088 | 5054.1.1.2 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans | 0.53 | 45.0 | 3.14e-01 | 100.0% | 28.3% |
| 3637195 | 142.1.1.0 ↗ | alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors | 0.52 | 36.0 | 3.35e-01 | 71.4% | 82.0% |
| 3581265 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.52 | 40.0 | 3.79e-01 | 80.5% | 86.7% |
| 4026345 | 108.1.1.0 ↗ | alpha arrays › EF-hand › EF-hand-related › EF-hand | 0.52 | 38.0 | 3.32e-01 | 98.7% | 51.3% |
| 3515314 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.52 | 39.0 | 3.24e-01 | 80.5% | 57.1% |
| 3624719 | 5076.1.1.1 ↗ | alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier › Mito_carr | 0.51 | 36.0 | 2.42e-01 | 74.0% | 90.0% |
| 3669967 | 109.4.1.263 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › UVSSA_N | 0.51 | 38.0 | 3.60e-01 | 81.8% | 71.6% |
| 3925588 | 4967.1.1.0 ↗ | alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases | 0.51 | 35.0 | 3.56e-01 | 71.4% | 80.0% |
| 3356077 | 109.4.1.1616 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_Trm732_C | 0.50 | 45.0 | 3.07e-01 | 100.0% | 55.0% |
| 3309012 | 604.3.1.1 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › BAG | 0.50 | 38.0 | 3.33e-01 | 80.5% | 67.8% |
| 3167402 | 108.1.1.116 ↗ | alpha arrays › EF-hand › EF-hand-related › EF-hand › SAGA-Tad1 | 0.50 | 43.0 | 4.14e-01 | 100.0% | 83.3% |
D2
high
residues 346-456
D3
medium
residues 14-28_191-265
D4
medium
residues 29-190
Domain cluster:
rep: putative_HD_superfamily_phosphohydrolase__YP_009052335__Aureococcus_anophagefferens_virus__1474867__D4-214
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF01966.29 best | HD | 34.2 | 3.70e-08 | 75.3% | 64.7% |