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putative_HNH_endonuclease

Euk-Vir

Aureococcus_anophagefferens_virus

putative_HNH_endonuclease__YP_009052374__Aureococcus_anophagefferens_virus__1474867

Identity

Accession:
YP_009052374 ↗
Protein ID:
putative_HNH_endonuclease
Kingdom:
euk

Quality

64.8 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 54-160
PDB
D2 high residues 167-254
PDB
Domain cluster: representative
CATH (13)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3wo4C02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.66 34.0 3.45e-01 86.4% 48.4%
1tygB00 3.10.20.30 Alpha Beta › Roll › Ubiquitin-like (UB roll) › Beta-grasp domain 0.65 30.0 3.41e-01 85.2% 56.9%
3bfoA00 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.63 35.0 3.60e-01 84.1% 56.5%
4devD01 2.60.120.260 Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding domain-like 0.59 35.0 3.17e-01 86.4% 41.6%
1cs6A04 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.56 33.0 3.31e-01 83.0% 56.7%
4igbB02 2.60.40.740 Mainly Beta › Sandwich › Immunoglobulin-like › 0.56 34.0 2.93e-01 83.0% 38.5%
3fysA01 3.40.50.10170 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.55 42.0 3.53e-01 81.8% 81.0%
7ok5A06 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.54 32.0 3.25e-01 81.8% 58.6%
4jglA00 2.40.128.530 Mainly Beta › Beta Barrel › Lipocalin › 0.54 41.0 3.42e-01 80.7% 82.2%
4a4yA01 2.60.200.50 Mainly Beta › Sandwich › Tumour Suppressor Smad4 › 0.54 44.0 4.25e-01 87.5% 100.0%
4kqdB00 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.53 40.0 3.67e-01 80.7% 81.0%
1wckA00 2.60.120.40 Mainly Beta › Sandwich › Jelly Rolls › 0.53 32.0 2.83e-01 81.8% 39.7%
5hs7B00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.52 27.0 2.64e-01 73.9% 41.8%
ECOD (17)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5070702 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.63 34.0 4.03e-01 81.8% 76.7%
5062279 11.1.1.284 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › PKD_4 0.63 35.0 3.49e-01 83.0% 51.1%
5060636 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.63 34.0 3.40e-01 85.2% 51.1%
5060604 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.56 35.0 3.33e-01 81.8% 55.0%
5077840 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.55 35.0 3.65e-01 81.8% 70.0%
3903025 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.55 35.0 3.25e-01 81.8% 50.4%
3571477 11.1.1.179 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Ig_3 0.55 33.0 3.27e-01 85.2% 55.8%
1722503 101.1.2.129 alpha arrays › HTH › HTH › winged helix domain › BpuJI_N 0.54 37.0 3.29e-01 71.6% 50.8%
3936161 633.23.1.5 alpha bundles › Bromodomain-like › Claudin › Claudin › Clc-like 0.54 41.0 3.12e-01 83.0% 95.3%
3261967 633.23.1.0 alpha bundles › Bromodomain-like › Claudin › Claudin 0.53 42.0 3.12e-01 84.1% 79.6%
3715053 11.2.1.23 beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain › B9-C2 0.53 39.0 3.12e-01 79.5% 100.0%
3628972 633.23.1.5 alpha bundles › Bromodomain-like › Claudin › Claudin › Clc-like 0.52 40.0 3.10e-01 84.1% 96.2%
4289835 304.48.1.1 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.52 45.0 3.44e-01 98.9% 86.2%
3250913 633.23.1.0 alpha bundles › Bromodomain-like › Claudin › Claudin 0.51 40.0 3.15e-01 86.4% 80.0%
3503188 633.23.1.5 alpha bundles › Bromodomain-like › Claudin › Claudin › Clc-like 0.51 39.0 3.14e-01 84.1% 100.0%
3255539 304.112.1.0 a+b two layers › Alpha-beta plaits › Argonaute, N-terminal domain › Argonaute, N-terminal domain 0.51 37.0 3.93e-01 79.5% 86.3%
3630405 633.23.1.5 alpha bundles › Bromodomain-like › Claudin › Claudin › Clc-like 0.51 39.0 3.05e-01 86.4% 77.7%
D3 high residues 259-383
PDB
ECOD (6)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3586841 378.1.1.7 few secondary structure elements › His-Me finger endonucleases › His-Me finger endonucleases › His-Me finger endonucleases › NUMOD4,HNH_3 0.62 54.0 5.58e-01 92.0% 100.0%
3873240 378.1.1.25 few secondary structure elements › His-Me finger endonucleases › His-Me finger endonucleases › His-Me finger endonucleases › MH1+NfI_DNAbd_pre-N 0.57 46.0 4.05e-01 85.6% 85.9%
4186324 378.1.1.4 few secondary structure elements › His-Me finger endonucleases › His-Me finger endonucleases › His-Me finger endonucleases › MH1 0.54 43.0 4.08e-01 84.0% 84.0%
2538864 378.1.1.4 few secondary structure elements › His-Me finger endonucleases › His-Me finger endonucleases › His-Me finger endonucleases › MH1 0.53 40.0 3.99e-01 79.2% 86.3%
3924746 378.1.1.4 few secondary structure elements › His-Me finger endonucleases › His-Me finger endonucleases › His-Me finger endonucleases › MH1 0.53 42.0 4.07e-01 84.0% 94.9%
3234539 378.1.1.4 few secondary structure elements › His-Me finger endonucleases › His-Me finger endonucleases › His-Me finger endonucleases › MH1 0.51 40.0 3.90e-01 83.2% 97.1%
D4 high residues 389-444
PDB
Domain cluster: representative
CATH (7)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1u3eM02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.77 61.0 5.70e-01 100.0% 70.6%
3go2A01 3.30.390.10 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain 0.62 46.0 3.68e-01 80.4% 82.5%
1qd1B02 3.30.70.670 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Formiminotransferase, C-terminal subdomain 0.58 43.0 3.21e-01 80.4% 60.7%
3gpvA00 1.10.1660.10 Mainly Alpha › Orthogonal Bundle › Multidrug-efflux Transporter Regulator; Chain: A; Domain 2 › 0.57 39.0 3.17e-01 71.4% 37.2%
3e3rB01 1.10.238.10 Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › EF-hand 0.53 44.0 3.92e-01 96.4% 91.8%
1epfA01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.53 41.0 3.40e-01 100.0% 49.0%
3oduB01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.51 40.0 2.70e-01 96.4% 90.3%
ECOD (3)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
2876 101.1.14.2 alpha arrays › HTH › HTH › DNA-binding domain of intron-encoded endonucleases › I-HmuI_NUMOD-like 0.77 61.0 5.67e-01 100.0% 69.6%
3242444 108.1.1.96 alpha arrays › EF-hand › EF-hand-related › EF-hand › EF-hand_1, EF-hand_6, EF-hand_7 0.58 49.0 4.62e-01 94.6% 98.6%
3969877 223.1.1.0 a+b three layers › Profilin-like › sensor domains › sensor domains 0.53 44.0 3.82e-01 100.0% 84.2%