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putative_NS2

Euk-Vir

Theilers_disease-associated_virus

putative_NS2__YP_009509000__Theilers_disease-associated_virus__1307119

Identity

Accession:
YP_009509000 ↗
Protein ID:
putative_NS2
Kingdom:
euk

Quality

79.2 mean pLDDT

Taxonomy

Orthornavirae› Kitrinoviricota› Flasuviricetes› Amarillovirales› Flaviviridae› Pegivirus› Theiler's_disease-associated_virus

TaxID: 1307119

Cluster

View cluster (7 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 4-106
PDB
Domain cluster: rep: putative_NS2_protein__YP_007697649_putative_NS2_protein__Equine_pegivirus_1__1307803__D26-126
D2 medium residues 173-222
PDB
Domain cluster: rep: putative_NS2_peptide__YP_009227301__Human_pegivirus_2__1729141__D193-239
CATH (32)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2hd0A02 2.30.30.710 Mainly Beta › Roll › SH3 type barrels. › Hepatitis C virus non-structural protein NS2, C-terminal domain 0.83 53.0 6.30e-01 70.0% 100.0%
3gqbA01 2.40.30.20 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › 0.81 56.0 4.88e-01 72.0% 57.7%
2w5eA02 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.80 55.0 4.75e-01 72.0% 56.8%
6oqrA01 2.40.30.20 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › 0.78 53.0 4.34e-01 72.0% 44.4%
1cq3A00 2.60.240.10 Mainly Beta › Sandwich › Viral Chemokine Inhibitor; Chain A › Major secreted virus protein 0.64 55.0 3.64e-01 100.0% 92.0%
2cxiA03 3.30.56.10 Alpha Beta › 2-Layer Sandwich › Phenylalanyl-tRNA Synthetase; Chain B, domain 1 › 0.64 44.0 3.95e-01 72.0% 65.7%
2gmlA02 3.30.70.1560 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Alpha-L RNA-binding motif 0.63 43.0 3.81e-01 72.0% 64.9%
4j27A02 2.60.40.1180 Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II 0.62 42.0 3.55e-01 72.0% 44.9%
1c7sA01 2.60.40.290 Mainly Beta › Sandwich › Immunoglobulin-like › 0.62 42.0 3.10e-01 74.0% 25.4%
4b60A01 2.60.40.1280 Mainly Beta › Sandwich › Immunoglobulin-like › 0.62 42.0 3.08e-01 72.0% 34.3%
4dt4A02 2.40.10.330 Mainly Beta › Beta Barrel › Thrombin, subunit H › 0.61 43.0 4.15e-01 76.0% 100.0%
2zylA01 2.102.10.10 Mainly Beta › 3-layer Sandwich › Rieske Iron-sulfur Protein › Rieske [2Fe-2S] iron-sulphur domain 0.61 48.0 3.65e-01 94.0% 91.1%
1d9yA02 3.40.190.10 Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II 0.60 51.0 3.70e-01 100.0% 59.5%
1xkpB00 3.30.1460.10 Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, › 0.60 41.0 3.19e-01 74.0% 40.5%
2w42B02 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.59 47.0 3.14e-01 94.0% 34.2%
1u2hA00 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.58 40.0 3.35e-01 76.0% 49.0%
6vg1A04 2.60.40.60 Mainly Beta › Sandwich › Immunoglobulin-like › Cadherins 0.58 39.0 3.20e-01 74.0% 46.2%
2p4bB02 3.30.200.100 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › MucB/RseB, C-terminal domain 0.57 44.0 3.68e-01 92.0% 55.1%
4i68A00 3.30.70.1800 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.57 48.0 4.04e-01 100.0% 73.3%
4a17E01 3.90.930.12 Alpha Beta › Alpha-Beta Complex › Outer Surface Protein A; domain 3 › Ribosomal protein L6 0.55 38.0 3.32e-01 74.0% 63.5%
1fhgA00 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.55 39.0 3.16e-01 76.0% 46.1%
5uv6A03 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.55 39.0 3.30e-01 76.0% 52.8%
1yk9A00 3.30.70.1230 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain 0.55 41.0 2.95e-01 88.0% 66.8%
5ao2B02 3.30.70.2760 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.55 37.0 3.28e-01 74.0% 67.4%
7y9aA01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.55 39.0 3.28e-01 76.0% 54.0%
1m3qA01 3.30.310.40 Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › 0.54 37.0 3.15e-01 72.0% 71.9%
3aqpA02 3.30.70.3220 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.54 36.0 2.65e-01 72.0% 34.4%
2yvsA02 3.30.70.2560 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.54 36.0 3.53e-01 72.0% 69.5%
2y23A01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.52 37.0 2.99e-01 76.0% 45.2%
1epfA01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.52 36.0 2.98e-01 74.0% 51.0%
3jtnB00 3.30.70.1950 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.52 41.0 3.56e-01 98.0% 85.6%
4liqE01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.51 35.0 3.14e-01 76.0% 47.4%
ECOD (29)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5076995 1.1.7.17 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › ATP-synt_ab_N 0.76 52.0 4.40e-01 72.0% 55.0%
4382401 1.1.7.100 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › PGBA_N 0.75 52.0 4.30e-01 72.0% 55.3%
3838015 319.3.1.3 ↗ beta sandwiches › HSP20-like › B2 domain of PilQ › B2 domain of PilQ › DUF7494 0.65 46.0 3.45e-01 76.0% 89.2%
3996681 389.2.1.3 ↗ few secondary structure elements › EGF-like › Serine protease inhibitors › Serine protease inhibitors › TIL_2 0.65 46.0 4.48e-01 76.0% 83.6%
4002600 389.4.1.7 ↗ few secondary structure elements › EGF-like › Fibulin-4 EGF-like 1 domain › Fibulin-4 EGF-like 1 domain › TIL_2 0.65 45.0 3.46e-01 76.0% 41.5%
4231688 1.1.7.0 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C 0.63 43.0 3.53e-01 74.0% 70.0%
4403052 2007.1.16.0 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Iron-sulphur enzyme Dph2 0.62 51.0 3.65e-01 92.0% 53.1%
2879522 244.1.1.0 ↗ a+b two layers › FAD-linked reductases, C-terminal domain-like › FAD-linked reductases-C › FAD-linked reductases-C 0.61 41.0 3.43e-01 72.0% 39.1%
3574542 390.1.1.1 ↗ few secondary structure elements › Hairpin loop containing domain-like › Hairpin loop containing domain-like › Hairpin loop containing domain-like › PAN_1 0.60 48.0 4.13e-01 100.0% 64.2%
4971139 304.28.1.0 ↗ a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain 0.60 40.0 3.73e-01 70.0% 53.8%
4937466 101.1.9.5 ↗ alpha arrays › HTH › HTH › Putative DNA-binding domain › B5 0.59 40.0 3.66e-01 72.0% 64.3%
1811230 244.1.1.0 ↗ a+b two layers › FAD-linked reductases, C-terminal domain-like › FAD-linked reductases-C › FAD-linked reductases-C 0.59 40.0 2.96e-01 72.0% 25.9%
6702 244.1.1.4 ↗ a+b two layers › FAD-linked reductases, C-terminal domain-like › FAD-linked reductases-C › FAD-linked reductases-C › DAO 0.59 40.0 3.37e-01 72.0% 40.9%
4931083 304.147.1.0 ↗ a+b two layers › Alpha-beta plaits › Tetrahydrodipicolinate acetyltransferase N-terminal domain › Tetrahydrodipicolinate acetyltransferase N-terminal domain 0.59 40.0 3.81e-01 72.0% 60.0%
3990256 390.1.1.0 ↗ few secondary structure elements › Hairpin loop containing domain-like › Hairpin loop containing domain-like › Hairpin loop containing domain-like 0.58 46.0 3.74e-01 100.0% 73.0%
3943581 881.4.1.1 ↗ a+b three layers › Mog1p/PsbP-like › C-terminal domain in sigma-E factor regulatory protein rseB › C-terminal domain in sigma-E factor regulatory protein rseB › MucB_RseB_C 0.57 45.0 3.60e-01 92.0% 49.1%
3738408 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.57 39.0 3.47e-01 74.0% 55.0%
1877510 244.1.1.0 ↗ a+b two layers › FAD-linked reductases, C-terminal domain-like › FAD-linked reductases-C › FAD-linked reductases-C 0.56 40.0 3.45e-01 78.0% 48.2%
4185829 3253.1.1.0 ↗ a+b two layers › ferredoxin-like domain in flagellar biosynthesis protein flhA › ferredoxin-like domain in flagellar biosynthesis protein flhA › ferredoxin-like domain in flagellar biosynthesis protein flhA 0.56 37.0 3.71e-01 100.0% 68.0%
5059893 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.55 38.0 3.06e-01 74.0% 50.9%
5082028 309.1.2.0 ↗ a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › ThrRS/AlaRS editing domain 0.55 37.0 2.71e-01 72.0% 22.5%
3548690 331.1.1.5 ↗ a+b two layers › TBP-like › TATA-box binding protein-like › TATA-box binding protein-like › OGG_N 0.54 37.0 3.32e-01 72.0% 78.7%
5069298 2492.1.1.18 ↗ a+b three layers › Cytidine deaminase-like › Cytidine deaminase-like › Cytidine deaminase-like › Prok-JAB 0.54 42.0 2.95e-01 92.0% 40.5%
3500022 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.53 35.0 3.13e-01 72.0% 48.8%
3899435 304.48.1.1 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.52 41.0 2.43e-01 90.0% 39.1%
3647392 304.3.1.0 ↗ a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain 0.52 32.0 3.15e-01 98.0% 51.7%
3877925 304.48.1.1 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.51 40.0 2.44e-01 90.0% 45.2%
4947796 309.1.2.2 ↗ a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › ThrRS/AlaRS editing domain › tRNA_bind_4 0.51 34.0 2.47e-01 72.0% 20.6%
3973484 7523.1.1.15 ↗ a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II › LysR_substrate 0.50 40.0 3.27e-01 92.0% 92.0%