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putative_NS3_peptide

Euk-Vir

Human_pegivirus_2

putative_NS3_peptide__YP_009227300__Human_pegivirus_2__1729141

Identity

Accession:
YP_009227300 ↗
Protein ID:
putative_NS3_peptide
Kingdom:
euk

Quality

82.3 mean pLDDT

Taxonomy

Orthornavirae› Kitrinoviricota› Flasuviricetes› Amarillovirales› Flaviviridae› Pegivirus› Human_pegivirus_2

TaxID: 1729141

Cluster

View cluster (30 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 12-85
PDB
D2 high residues 102-168
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02907.22 best Peptidase_S29 48.0 1.70e-12 100.0% 43.6%
CATH (44)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1a1rA02 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.98 94.0 8.52e-01 100.0% 80.0%
4b6eB01 2.40.10.120 Mainly Beta › Beta Barrel › Thrombin, subunit H › 0.96 91.0 6.17e-01 100.0% 33.7%
3otpA01 2.40.10.120 Mainly Beta › Beta Barrel › Thrombin, subunit H › 0.80 73.0 5.07e-01 100.0% 39.4%
1ep5A02 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.78 62.0 5.74e-01 100.0% 67.4%
1m9uA01 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.78 70.0 5.59e-01 100.0% 78.0%
2w5eA02 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.78 67.0 6.52e-01 100.0% 85.1%
2rceA02 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.77 71.0 6.00e-01 100.0% 73.6%
2rdlA01 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.77 70.0 5.75e-01 100.0% 75.4%
3k6yA02 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.77 71.0 5.96e-01 100.0% 77.6%
1arbA01 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.76 69.0 5.60e-01 100.0% 70.5%
3cp7B02 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.76 69.0 5.87e-01 100.0% 74.3%
1wczA01 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.75 69.0 5.67e-01 100.0% 60.0%
2ey4D00 2.40.10.230 Mainly Beta › Beta Barrel › Thrombin, subunit H › Probable tRNA pseudouridine synthase domain 0.74 58.0 5.59e-01 86.6% 74.7%
1wzoA01 2.30.30.370 Mainly Beta › Roll › SH3 type barrels. › FAH 0.74 36.0 4.49e-01 100.0% 77.5%
2olgA02 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.74 67.0 5.53e-01 100.0% 85.2%
1eq9A01 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.74 66.0 5.48e-01 100.0% 76.1%
5fahA01 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.73 65.0 5.43e-01 100.0% 76.1%
3h7tB01 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.73 66.0 5.38e-01 100.0% 77.9%
2as9B01 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.73 64.0 5.48e-01 100.0% 62.4%
3stjA01 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.72 64.0 5.95e-01 100.0% 82.4%
2xxlA02 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.72 64.0 4.96e-01 100.0% 69.2%
5hmaA02 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.71 64.0 5.52e-01 100.0% 76.0%
3u28C00 2.40.10.230 Mainly Beta › Beta Barrel › Thrombin, subunit H › Probable tRNA pseudouridine synthase domain 0.70 56.0 5.06e-01 88.1% 63.0%
1agjA01 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.70 64.0 5.00e-01 100.0% 54.5%
1p3cA01 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.69 61.0 5.26e-01 100.0% 72.4%
3r5lA00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.69 59.0 5.01e-01 100.0% 92.2%
4ic5A02 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.68 63.0 5.36e-01 100.0% 71.2%
2fg9A01 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.68 59.0 4.56e-01 100.0% 78.6%
1mbmA01 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.68 54.0 5.26e-01 100.0% 78.9%
4yo1A01 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.68 58.0 5.36e-01 100.0% 78.7%
3l6pA02 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.68 61.0 5.24e-01 100.0% 63.8%
3girA04 2.40.30.110 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Aminomethyltransferase beta-barrel domains 0.67 44.0 4.25e-01 74.6% 59.0%
4r8tB02 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.66 55.0 5.40e-01 100.0% 83.6%
1ylnA01 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.65 56.0 4.81e-01 100.0% 75.4%
2bhgA02 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.63 54.0 4.80e-01 100.0% 74.5%
2zzeA03 2.40.30.130 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › 0.63 52.0 4.60e-01 92.5% 68.4%
2sfaA01 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.60 51.0 4.69e-01 100.0% 78.0%
6f2mA02 2.40.30.290 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › 0.59 48.0 4.50e-01 94.0% 75.9%
3nrfA00 2.60.40.4110 Mainly Beta › Sandwich › Immunoglobulin-like › Protein of unknown function DUF4354 0.55 43.0 3.83e-01 88.1% 80.4%
2pliA00 3.30.465.10 Alpha Beta › 2-Layer Sandwich › Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 › 0.54 40.0 3.72e-01 80.6% 94.0%
5xd6B01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.53 45.0 4.11e-01 100.0% 69.1%
2n0kA00 2.60.40.790 Mainly Beta › Sandwich › Immunoglobulin-like › 0.52 39.0 3.64e-01 83.6% 93.3%
3igfA02 2.60.40.790 Mainly Beta › Sandwich › Immunoglobulin-like › 0.52 39.0 3.83e-01 83.6% 93.2%
2zxdA02 2.60.40.1180 Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II 0.52 44.0 4.04e-01 100.0% 92.3%
ECOD (67)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
1161323 1.1.5.14 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Peptidase_S29 0.97 92.0 6.42e-01 100.0% 37.6%
3194806 1.1.17.0 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 0.80 73.0 4.71e-01 100.0% 33.4%
4053143 1.1.5.6 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Peptidase_S7 0.80 51.0 4.17e-01 74.6% 36.7%
3948218 1.1.17.3 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin_2 0.80 73.0 4.86e-01 100.0% 32.7%
5035938 1.1.17.0 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 0.80 73.0 4.95e-01 100.0% 36.0%
4247805 1.1.5.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Trypsin 0.79 74.0 5.04e-01 100.0% 35.1%
4387060 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.79 73.0 4.99e-01 100.0% 34.4%
None — 0.79 73.0 5.01e-01 100.0% 35.2%
4031177 1.1.5.33 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Trypsin_2 0.78 72.0 4.93e-01 100.0% 34.6%
5023947 1.1.17.0 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 0.78 71.0 5.17e-01 100.0% 38.8%
4960051 1.1.5.0 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 0.78 71.0 5.15e-01 100.0% 46.6%
3394182 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.78 70.0 4.77e-01 100.0% 39.9%
5010595 1.1.7.0 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C 0.78 65.0 5.95e-01 89.6% 75.3%
3654499 1.1.5.33 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Trypsin_2 0.77 72.0 5.71e-01 100.0% 63.2%
3454710 1.1.17.0 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 0.77 69.0 4.74e-01 100.0% 41.4%
2429362 1.1.5.4 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Peptidase_S3 0.76 61.0 4.41e-01 100.0% 32.2%
4883897 1.1.17.3 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin_2 0.75 67.0 4.53e-01 100.0% 33.6%
1826904 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.75 67.0 4.52e-01 100.0% 33.5%
5063379 1.1.17.3 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin_2 0.75 68.0 4.92e-01 100.0% 40.0%
3409561 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.75 66.0 4.57e-01 100.0% 39.6%
2512790 1.1.5.33 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Trypsin_2 0.75 67.0 4.53e-01 100.0% 32.8%
1096110 1.1.17.3 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin_2 0.75 69.0 4.72e-01 100.0% 31.9%
22087 1.1.5.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Trypsin 0.75 66.0 4.49e-01 100.0% 33.9%
5059785 1.1.7.0 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C 0.74 61.0 5.75e-01 89.6% 76.2%
3305298 1.1.5.33 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Trypsin_2 0.74 62.0 5.06e-01 91.0% 70.0%
3248403 1.1.5.0 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 0.74 63.0 4.97e-01 100.0% 46.7%
3283246 1.1.16.1 ↗ beta barrels › cradle loop barrel › RIFT-related › Mammalian cell entry (MCE) domain › MlaD 0.74 48.0 3.74e-01 74.6% 31.0%
3448643 1.1.5.0 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 0.73 66.0 4.62e-01 100.0% 39.0%
4620869 1.1.5.57 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Mycop_pep_DUF31 0.73 66.0 4.10e-01 100.0% 29.8%
4881628 1.1.5.4 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Peptidase_S3 0.73 58.0 5.49e-01 100.0% 72.0%
4964309 1.1.7.20 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › Gar1 0.73 57.0 5.53e-01 88.1% 77.0%
5048051 1.1.7.20 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › Gar1 0.73 56.0 5.13e-01 86.6% 62.9%
3406002 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.73 65.0 4.48e-01 100.0% 31.4%
4942485 1.1.7.20 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › Gar1 0.73 62.0 5.89e-01 97.0% 78.8%
3393350 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.72 64.0 4.55e-01 100.0% 32.7%
3172153 1.1.7.20 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › Gar1 0.72 58.0 4.86e-01 88.1% 53.0%
3962616 1.1.5.33 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Trypsin_2 0.72 64.0 4.75e-01 100.0% 48.8%
5041618 1.1.7.20 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › Gar1 0.72 57.0 5.16e-01 88.1% 64.9%
5051893 1.1.7.20 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › Gar1 0.72 57.0 5.43e-01 88.1% 77.5%
4991129 1.1.7.0 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C 0.72 56.0 5.18e-01 88.1% 66.7%
4945432 1.1.7.0 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C 0.72 57.0 5.28e-01 89.6% 68.2%
3732331 1.1.7.20 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › Gar1 0.71 57.0 4.85e-01 88.1% 54.5%
3996398 1.1.7.0 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C 0.71 56.0 5.17e-01 89.6% 67.1%
3439936 1.1.17.3 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin_2 0.71 63.0 4.11e-01 100.0% 29.8%
3674829 1.1.13.61 ↗ beta barrels › cradle loop barrel › RIFT-related › Phage tail proteins › Gar1 0.71 61.0 6.08e-01 100.0% 91.4%
3185402 1.1.7.20 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › Gar1 0.70 56.0 4.86e-01 88.1% 58.1%
2869319 1.1.7.20 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › Gar1 0.70 56.0 4.95e-01 88.1% 61.2%
4969578 1.1.7.0 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C 0.70 54.0 5.25e-01 88.1% 75.7%
3106034 1.1.5.33 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Trypsin_2 0.69 62.0 4.20e-01 100.0% 31.0%
169988 1.1.5.6 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Peptidase_S7 0.69 60.0 4.47e-01 100.0% 42.8%
4059005 1.1.17.23 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Peptidase_S7 0.69 60.0 4.05e-01 100.0% 41.9%
4472606 1.1.13.55 ↗ beta barrels › cradle loop barrel › RIFT-related › Phage tail proteins › DUF4873 0.69 59.0 5.24e-01 100.0% 77.0%
5046975 1.1.7.21 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › RIBIOP_C 0.68 54.0 5.16e-01 89.6% 73.8%
5073223 1.1.7.0 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C 0.68 55.0 5.10e-01 89.6% 70.6%
4999166 1.1.7.0 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C 0.66 53.0 5.18e-01 89.6% 80.0%
4822902 1.1.17.3 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin_2 0.66 59.0 4.44e-01 100.0% 44.9%
4499041 1.1.5.57 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Mycop_pep_DUF31 0.66 59.0 4.13e-01 100.0% 39.0%
4886128 613.1.1.1 ↗ alpha complex topology › Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) › Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) › Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) › tRNA-synt_2c 0.65 54.0 4.63e-01 92.5% 70.9%
4440308 1.1.7.11 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › RimM 0.64 50.0 4.56e-01 88.1% 64.2%
4068826 1.1.7.11 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › RimM 0.63 49.0 4.52e-01 86.6% 67.8%
4322439 1.1.7.9 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › tRNA-synt_2c 0.63 52.0 4.43e-01 92.5% 60.9%
4259247 1.11.1.1 ↗ beta barrels › cradle loop barrel › Photosystem II accessory factor Psb28 › Photosystem II accessory factor Psb28 › Psb28 0.62 52.0 4.68e-01 98.5% 78.8%
4553723 1.1.7.11 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › RimM 0.61 47.0 4.32e-01 88.1% 66.3%
4525111 1.1.7.126 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › Peptidase_S7 0.61 55.0 5.22e-01 100.0% 95.0%
4070395 1.1.1.28 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease › Asp, TAXi_C, TAXi_N 0.59 49.0 3.17e-01 100.0% 37.1%
5037939 4.11.1.0 ↗ beta barrels › SH3 › LexA/Signal peptidase › LexA/Signal peptidase 0.58 37.0 2.92e-01 91.0% 28.4%
2648304 11.1.1.158 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › GldM_4th 0.54 45.0 3.88e-01 100.0% 79.8%
D3 high residues 194-322
PDB
Domain cluster: rep: B962L__YP_009703129__African_swine_fever_virus__10497__D53-65_81-193
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00270.36 best DEAD 31.8 1.60e-07 97.7% 68.3%
D4 high residues 336-475
PDB
Domain cluster: rep: B962L__YP_009703129__African_swine_fever_virus__10497__D237-425
D5 high residues 492-622
PDB
Domain cluster: rep: putative_NS3_protein__YP_007905979__Rodent_pegivirus__1321391__D503-601