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putative_NS5B_peptide
Euk-VirHuman_pegivirus_2
putative_NS5B_peptide__YP_009227296__Human_pegivirus_2__1729141
Identity
- Accession:
- YP_009227296 ↗
- Protein ID:
- putative_NS5B_peptide
- Kingdom:
- euk
Quality
88.5
mean pLDDT
Taxonomy
Orthornavirae›
Kitrinoviricota›
Flasuviricetes›
Amarillovirales›
Flaviviridae›
Pegivirus›
Human_pegivirus_2
TaxID: 1729141
Cluster
View cluster (450 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 353-566
Domain cluster:
rep: NS5B_RNA-dependent_RNA_polymerase__YP_009272656__Hepatitis_C_virus_genotype_5__33746__D391-472_498-585
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00998.29 best | RdRP_3 | 27.2 | 2.30e-06 | 65.0% | 25.1% |
CATH (3)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 7ru9C01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.54 | 34.0 | 3.14e-01 | 71.0% | 48.7% |
| 7yb9A01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.53 | 30.0 | 3.06e-01 | 74.8% | 52.8% |
| 6hftA01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.51 | 27.0 | 3.41e-01 | 74.8% | 83.5% |
ECOD (4)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 150973 | 4967.1.1.5 ↗ | alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › RdRP_3 | 0.89 | 76.0 | 7.61e-01 | 87.9% | 89.8% |
| 3781 | 4967.1.1.0 ↗ | alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases | 0.74 | 59.0 | 6.31e-01 | 86.4% | 93.7% |
| 2770736 | 4967.1.1.14 ↗ | alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › Flavi_NS5_thumb | 0.73 | 60.0 | 6.29e-01 | 92.5% | 94.3% |
| 4010264 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.56 | 28.0 | 3.71e-01 | 93.5% | 85.6% |
D2
medium
residues 39-182_219-270
Domain cluster:
rep: hypothetical_protein_3__YP_009345007__Wuhan_spider_virus_8__1923757__D1-105_147-200
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00998.29 best | RdRP_3 | 50.0 | 2.80e-13 | 74.5% | 28.4% |
ECOD (13)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 217141 | 304.48.1.15 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RdRP_3 | 0.93 | 90.0 | 7.10e-01 | 100.0% | 66.1% |
| 1279063 | 304.48.1.13 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Flavi_NS5 | 0.86 | 82.0 | 6.13e-01 | 100.0% | 58.6% |
| 5366 | 304.48.1.15 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RdRP_3 | 0.85 | 81.0 | 6.21e-01 | 100.0% | 61.6% |
| 3928801 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.79 | 74.0 | 5.98e-01 | 99.0% | 69.1% |
| 1789314 | 304.48.1.8 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RdRP_1 | 0.78 | 73.0 | 5.72e-01 | 100.0% | 60.7% |
| 3927049 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.78 | 73.0 | 5.63e-01 | 100.0% | 62.4% |
| 3938749 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.77 | 72.0 | 5.72e-01 | 100.0% | 68.6% |
| 3937215 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.75 | 70.0 | 5.50e-01 | 100.0% | 64.8% |
| 3691350 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.73 | 68.0 | 6.06e-01 | 99.0% | 89.3% |
| 3473558 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.72 | 64.0 | 6.05e-01 | 94.4% | 99.6% |
| 4330406 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.70 | 66.0 | 5.27e-01 | 100.0% | 63.2% |
| 3267570 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.58 | 54.0 | 4.38e-01 | 98.5% | 82.6% |
| 4633863 | 304.28.1.1 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › ACR_tran | 0.56 | 20.0 | 2.60e-01 | 74.5% | 53.0% |
D3
medium
residues 183-218_271-352
Domain cluster:
rep: hypothetical_protein_2__YP_009337040__Changjiang_tombus-like_virus_21__1922815__D1-47_99-181
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00998.29 best | RdRP_3 | 66.2 | 3.40e-18 | 69.5% | 16.9% |