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putative_NS5B_peptide

Euk-Vir

Human_pegivirus_2

putative_NS5B_peptide__YP_009227296__Human_pegivirus_2__1729141

Identity

Accession:
YP_009227296 ↗
Protein ID:
putative_NS5B_peptide
Kingdom:
euk

Quality

88.5 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 353-566
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00998.29 best RdRP_3 27.2 2.30e-06 65.0% 25.1%
CATH (3)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
7ru9C01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.54 34.0 3.14e-01 71.0% 48.7%
7yb9A01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.53 30.0 3.06e-01 74.8% 52.8%
6hftA01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.51 27.0 3.41e-01 74.8% 83.5%
ECOD (4)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
150973 4967.1.1.5 alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › RdRP_3 0.89 76.0 7.61e-01 87.9% 89.8%
3781 4967.1.1.0 alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.74 59.0 6.31e-01 86.4% 93.7%
2770736 4967.1.1.14 alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › Flavi_NS5_thumb 0.73 60.0 6.29e-01 92.5% 94.3%
4010264 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.56 28.0 3.71e-01 93.5% 85.6%
D2 medium residues 39-182_219-270
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00998.29 best RdRP_3 50.0 2.80e-13 74.5% 28.4%
ECOD (13)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
217141 304.48.1.15 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RdRP_3 0.93 90.0 7.10e-01 100.0% 66.1%
1279063 304.48.1.13 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Flavi_NS5 0.86 82.0 6.13e-01 100.0% 58.6%
5366 304.48.1.15 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RdRP_3 0.85 81.0 6.21e-01 100.0% 61.6%
3928801 304.48.1.1 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.79 74.0 5.98e-01 99.0% 69.1%
1789314 304.48.1.8 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RdRP_1 0.78 73.0 5.72e-01 100.0% 60.7%
3927049 304.48.1.1 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.78 73.0 5.63e-01 100.0% 62.4%
3938749 304.48.1.1 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.77 72.0 5.72e-01 100.0% 68.6%
3937215 304.48.1.1 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.75 70.0 5.50e-01 100.0% 64.8%
3691350 304.48.1.1 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.73 68.0 6.06e-01 99.0% 89.3%
3473558 304.48.1.1 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.72 64.0 6.05e-01 94.4% 99.6%
4330406 304.48.1.1 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.70 66.0 5.27e-01 100.0% 63.2%
3267570 304.48.1.1 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.58 54.0 4.38e-01 98.5% 82.6%
4633863 304.28.1.1 a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › ACR_tran 0.56 20.0 2.60e-01 74.5% 53.0%
D3 medium residues 183-218_271-352
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00998.29 best RdRP_3 66.2 3.40e-18 69.5% 16.9%