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putative_RNA-dependent_RNA_polymerase

Euk-Vir

Fusarium_graminearum_dsRNA_mycovirus-3

putative_RNA-dependent_RNA_polymerase__YP_003288789__Fusarium_graminearum_dsRNA_mycovirus-3__687917

Identity

Accession:
YP_003288789 ↗
Protein ID:
putative_RNA-dependent_RNA_polymerase
Kingdom:
euk

Quality

80.5 mean pLDDT

Cluster

View cluster (7 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 61-230
PDB
D2 medium residues 231-389
PDB
Domain cluster: rep: RNA-dependent_RNA_polymerase__YP_009272909__Fusarium_poae_mycovirus_1__1849542__D237-378
ECOD (4)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
1790170 1050.1.1.0 ↗ alpha arrays › BID domain of Bartonella effector protein (Bep) › BID domain of Bartonella effector protein (Bep) › BID domain of Bartonella effector protein (Bep) 0.61 40.0 4.27e-01 87.4% 75.2%
3414515 633.12.1.0 ↗ alpha bundles › Bromodomain-like › Ta0600-like › Ta0600-like 0.58 38.0 4.02e-01 81.1% 73.1%
3442617 174.1.1.0 ↗ few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.52 34.0 3.38e-01 82.4% 61.2%
3219672 601.1.2.79 ↗ alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › TMEM126_like 0.51 42.0 3.90e-01 86.8% 96.9%
D3 medium residues 390-554_593-664
PDB
Domain cluster: rep: hypothetical_protein_2__YP_009336713__Beihai_toti-like_virus_4__1922734__D167-187_213-323_360-427
CATH (1)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1vw4T01 6.10.330.20 Special › Helix non-globular › Monooxygenase › 0.58 25.0 3.61e-01 76.8% 83.9%
ECOD (6)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4516798 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.63 48.0 3.81e-01 78.5% 44.8%
3598902 304.48.1.0 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.62 49.0 4.17e-01 82.7% 60.5%
3792091 304.48.1.25 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RRM_4 0.62 49.0 4.31e-01 82.7% 60.0%
3616117 601.1.1.25 ↗ alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › GIT1_C 0.56 22.0 3.19e-01 78.1% 75.0%
3514483 532.2.1.10 ↗ alpha arrays › Type III secretion system domain-like › Type III secretion system domains › Type III secretion system domains › NTP_transf_7 0.52 23.0 3.16e-01 70.0% 80.0%
3291430 106.1.1.11 ↗ alpha arrays › Globin-like › Globin-like › Globin-like › RsbRD_N 0.50 26.0 3.32e-01 80.2% 82.1%
D4 medium residues 555-592_665-759
PDB
Domain cluster: rep: hypothetical_protein_2__YP_009337040__Changjiang_tombus-like_virus_21__1922815__D1-47_99-181
D5 medium residues 805-867
PDB
Domain cluster: rep: RNA-dependent_RNA_polymerase__YP_009272909__Fusarium_poae_mycovirus_1__1849542__D840-898
D6 medium residues 1121-1147_1240-1311
PDB
Domain cluster: representative
CATH (17)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
5b00A00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.70 49.0 3.60e-01 72.7% 31.4%
3d36B02 1.10.287.130 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain 0.70 35.0 4.39e-01 92.9% 78.7%
1v4aA01 1.10.4050.10 Mainly Alpha › Orthogonal Bundle › Nucleotidyltransferase substrate binding subunit/domain fold › Glutamine synthase adenylyltransferase GlnE 0.66 39.0 3.81e-01 92.9% 53.2%
1cqxA01 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.63 42.0 3.63e-01 93.9% 44.7%
3lmfA00 1.20.1270.360 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.60 34.0 3.36e-01 96.0% 49.5%
3ubcA00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.60 36.0 3.26e-01 85.9% 44.3%
3lk5A00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.57 50.0 3.53e-01 99.0% 59.2%
3rkoG00 1.10.287.3510 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.57 37.0 3.78e-01 87.9% 65.0%
4hzuS00 1.10.1760.20 Mainly Alpha › Orthogonal Bundle › Arp2/3 complex 21 kDa subunit ARPC3 › 0.57 50.0 4.17e-01 93.9% 73.2%
4w4kA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.55 34.0 3.75e-01 92.9% 75.6%
1ej6B00 3.90.1830.10 Alpha Beta › Alpha-Beta Complex › Inner capsid protein lambda-1 › Inner capsid protein lambda-1 0.53 46.0 2.68e-01 99.0% 62.5%
3dyjA02 1.20.1420.10 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain 0.52 39.0 3.42e-01 91.9% 51.7%
4akgA14 1.20.1280.160 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.52 45.0 4.36e-01 93.9% 97.2%
3c18A02 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.52 36.0 3.46e-01 93.9% 60.2%
1urvA00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.51 39.0 3.35e-01 85.9% 51.3%
2vxxA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.50 40.0 3.36e-01 85.9% 74.4%
1tjoB00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.50 40.0 3.33e-01 85.9% 73.1%
ECOD (12)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3914806 106.1.1.1 ↗ alpha arrays › Globin-like › Globin-like › Globin-like › Globin 0.64 42.0 3.61e-01 93.9% 42.6%
3712208 2484.8.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Separase pseudo-protease domain (PPD) › Separase pseudo-protease domain (PPD) 0.58 53.0 3.75e-01 99.0% 38.9%
3741819 601.1.2.80 ↗ alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Yip1 0.58 39.0 3.57e-01 86.9% 51.1%
3530312 2485.1.1.120 ↗ a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like › Strabismus 0.53 33.0 3.06e-01 81.8% 49.2%
4578863 106.1.1.1 ↗ alpha arrays › Globin-like › Globin-like › Globin-like › Globin 0.52 41.0 3.48e-01 93.9% 51.6%
3623181 106.1.1.1 ↗ alpha arrays › Globin-like › Globin-like › Globin-like › Globin 0.52 43.0 3.61e-01 93.9% 53.3%
3650746 2003.1.5.30 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_7 0.52 43.0 2.88e-01 89.9% 61.8%
3595205 632.7.1.0 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain 0.51 29.0 2.25e-01 89.9% 23.2%
3177042 601.1.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.50 32.0 3.16e-01 87.9% 58.2%
4978616 604.39.1.3 ↗ alpha bundles › Spectrin repeat-like › S-component of energy-coupling factor (ECF) transporters › S-component of energy-coupling factor (ECF) transporters › ECF-ribofla_trS 0.50 42.0 3.53e-01 94.9% 68.5%
3193113 5051.1.1.10 ↗ alpha complex topology › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › AA_permease_2 0.50 45.0 2.87e-01 98.0% 66.5%
4260399 106.1.1.1 ↗ alpha arrays › Globin-like › Globin-like › Globin-like › Globin 0.50 37.0 3.29e-01 84.8% 53.1%
D7 medium residues 1148-1239
PDB
Domain cluster: representative
CATH (16)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2guzB00 1.10.287.110 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › DnaJ domain 0.62 42.0 4.91e-01 83.7% 98.5%
2gscC00 1.20.1440.60 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence 0.61 50.0 4.73e-01 88.0% 94.5%
2w4sA00 1.10.10.1440 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › PHAX RNA-binding domain 0.61 42.0 4.32e-01 70.7% 87.2%
3ajfA00 1.20.1440.190 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Tenuivirus movement protein 0.60 47.0 4.80e-01 84.8% 93.5%
2is6A04 1.10.486.10 Mainly Alpha › Orthogonal Bundle › PCRA; domain 4 › PCRA; domain 4 0.56 48.0 4.00e-01 95.7% 98.1%
1cmjA00 1.10.630.10 Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 0.55 42.0 2.84e-01 84.8% 59.1%
3t8vA05 1.25.50.10 Mainly Alpha › Alpha Horseshoe › Zincin-like fold › Peptidase M1, alanyl aminopeptidase, C-terminal domain 0.55 39.0 2.65e-01 75.0% 68.7%
4iluA02 1.20.58.1290 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › CarD-like, C-terminal domain 0.55 35.0 3.31e-01 71.7% 53.2%
1yxrA01 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.54 39.0 4.28e-01 75.0% 94.6%
2ongA01 1.50.10.130 Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › Terpene synthase, N-terminal domain 0.54 39.0 3.04e-01 75.0% 45.6%
2a0uB01 1.20.120.420 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › translation initiation factor eif-2b, domain 1 0.54 46.0 3.88e-01 95.7% 74.4%
1z19A01 1.10.150.130 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Tyrosine recombinase, N-terminal domain 0.53 40.0 3.95e-01 84.8% 75.0%
6fhpD00 1.10.390.10 Mainly Alpha › Orthogonal Bundle › Neutral Protease; domain 2 › Neutral Protease Domain 2 0.52 34.0 3.83e-01 70.7% 100.0%
4chdA00 3.30.70.3510 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.51 39.0 3.49e-01 84.8% 92.6%
1yc9A01 1.20.1600.10 Mainly Alpha › Up-down Bundle › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) 0.50 42.0 2.95e-01 94.6% 100.0%
2vsoF01 1.25.40.180 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.50 41.0 3.05e-01 87.0% 54.5%
ECOD (25)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3493379 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.68 48.0 4.37e-01 72.8% 90.8%
5068709 633.12.1.0 ↗ alpha bundles › Bromodomain-like › Ta0600-like › Ta0600-like 0.65 51.0 5.18e-01 82.6% 94.4%
4350232 141.1.1.3 ↗ alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases › UbiA 0.62 47.0 3.33e-01 81.5% 85.8%
4461398 5085.1.1.1 ↗ a+b duplicates or obligate multimers › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) › OEP 0.60 42.0 2.68e-01 72.8% 81.5%
4998475 180.1.1.0 ↗ alpha bundles › Acid phosphatase/Vanadium-dependent haloperoxidase › Acid phosphatase/Vanadium-dependent haloperoxidase › Acid phosphatase/Vanadium-dependent haloperoxidase 0.60 48.0 3.87e-01 89.1% 88.8%
3481781 604.12.1.1 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT 0.59 41.0 4.41e-01 71.7% 86.3%
4954693 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.59 37.0 3.70e-01 73.9% 61.1%
3248730 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.58 40.0 3.68e-01 71.7% 55.7%
3429545 3651.1.1.1 ↗ alpha bundles › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › IF-2B 0.58 49.0 4.43e-01 92.4% 81.6%
3538287 108.1.1.144 ↗ alpha arrays › EF-hand › EF-hand-related › EF-hand › Dockerin_1 0.57 42.0 3.69e-01 76.1% 94.1%
3719118 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.57 46.0 2.98e-01 84.8% 27.8%
5074606 601.28.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › VPS28 C-terminal domain-like › VPS28 C-terminal domain-like 0.57 43.0 4.26e-01 84.8% 75.0%
3719217 109.4.1.657 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › DUF4042 0.57 46.0 2.68e-01 85.9% 18.2%
5045889 601.28.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › VPS28 C-terminal domain-like › VPS28 C-terminal domain-like 0.57 42.0 4.34e-01 85.9% 85.9%
4975294 601.28.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › VPS28 C-terminal domain-like › VPS28 C-terminal domain-like 0.55 42.0 4.27e-01 85.9% 83.3%
3609786 568.1.1.0 ↗ few secondary structure elements › p8-MTCP1-related › p8-MTCP1-related › p8-MTCP1-related 0.55 37.0 3.60e-01 98.9% 62.0%
4972788 601.2.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › Cytochromes › Cytochromes 0.55 40.0 3.82e-01 77.2% 75.5%
4235833 109.4.1.2877 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_2, ANAPC3, TPR_8, TPR_16, TPR_19, TTC7_N 0.55 42.0 2.48e-01 83.7% 14.9%
5051835 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.54 43.0 2.87e-01 82.6% 23.0%
4975293 601.28.1.1 ↗ alpha bundles › Four-helical up-and-down bundle › VPS28 C-terminal domain-like › VPS28 C-terminal domain-like › VPS28 0.54 42.0 4.18e-01 85.9% 81.0%
4402544 304.41.1.1 ↗ a+b two layers › Alpha-beta plaits › Glutamyl tRNA-reductase catalytic, N-terminal domain › Glutamyl tRNA-reductase catalytic, N-terminal domain › GlutR_N 0.54 41.0 3.63e-01 81.5% 100.0%
4954682 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.51 39.0 3.88e-01 80.4% 86.3%
3948503 101.1.1.355 ↗ alpha arrays › HTH › HTH › Three-helical HTH › DUF2857 0.51 33.0 3.63e-01 92.4% 85.7%
5057127 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.50 40.0 2.88e-01 84.8% 31.4%
5053257 601.28.1.1 ↗ alpha bundles › Four-helical up-and-down bundle › VPS28 C-terminal domain-like › VPS28 C-terminal domain-like › VPS28 0.50 37.0 3.74e-01 88.0% 78.9%