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putative_RNA-dependent_RNA_polymerase
Euk-VirMaize-associated_totivirus_2
putative_RNA-dependent_RNA_polymerase__YP_009259486__Maize-associated_totivirus_2__1874267
Identity
- Accession:
- YP_009259486 ↗
- Protein ID:
- putative_RNA-dependent_RNA_polymerase
- Kingdom:
- euk
Quality
87.0
mean pLDDT
Cluster
View cluster (56 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 27-108
D2
high
residues 121-269_595-612
D3
medium
residues 271-306_380-405_450-515
Domain cluster:
rep: RNA-dependent_RNA_polymerase__YP_009143529__Sclerotinia_sclerotiorum_megabirnavirus_1__1661257__D510-583_640-668
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF02123.22 best | RdRP_4 | 30.4 | 2.80e-07 | 55.5% | 13.3% |
D4
medium
residues 307-379_406-421
Domain cluster:
representative
D5
medium
residues 422-449_516-594
Domain cluster:
rep: KR816341.1__AKQ06880.1__X__00021__D162-195_238-325
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF02123.22 best | RdRP_4 | 53.4 | 3.10e-14 | 75.7% | 16.8% |
CATH (79)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1gx5A03 | 3.30.70.270 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain | 0.85 | 75.0 | 7.18e-01 | 93.5% | 94.3% |
| 4hkqA01 | 3.30.70.270 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain | 0.77 | 71.0 | 6.39e-01 | 100.0% | 79.2% |
| 1cc8A00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.76 | 50.0 | 5.89e-01 | 75.7% | 98.6% |
| 2r7rA04 | 3.30.70.2480 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.74 | 68.0 | 5.95e-01 | 100.0% | 76.4% |
| 1in0A01 | 3.30.70.860 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.74 | 48.0 | 5.73e-01 | 72.9% | 100.0% |
| 3jcmH04 | 3.30.70.870 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Elongation Factor G (Translational Gtpase), domain 3 | 0.72 | 50.0 | 5.79e-01 | 85.0% | 100.0% |
| 1konA03 | 3.30.70.980 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › YebC, transcriptional regulation domain | 0.71 | 47.0 | 5.42e-01 | 90.7% | 96.0% |
| 2yweA03 | 3.30.70.870 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Elongation Factor G (Translational Gtpase), domain 3 | 0.71 | 49.0 | 5.50e-01 | 73.8% | 92.7% |
| 2dy1A03 | 3.30.70.870 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Elongation Factor G (Translational Gtpase), domain 3 | 0.70 | 48.0 | 5.53e-01 | 83.2% | 97.4% |
| 4oloB00 | 3.30.70.1710 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › BMC (bacterial microcompartment) domain | 0.70 | 42.0 | 4.66e-01 | 72.9% | 75.0% |
| 1vbkA01 | 3.30.70.1510 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › THUMP domain-like | 0.70 | 52.0 | 5.87e-01 | 85.0% | 100.0% |
| 3h5xA03 | 3.30.70.270 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain | 0.70 | 63.0 | 6.20e-01 | 99.1% | 97.4% |
| 2fyxA00 | 3.30.70.1290 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Transposase IS200-like | 0.70 | 54.0 | 5.11e-01 | 83.2% | 87.7% |
| 4oi3A00 | 3.30.70.3090 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ORF SCO4226, nickel-binding ferredoxin-like monomer | 0.69 | 50.0 | 5.65e-01 | 83.2% | 100.0% |
| 1vi7A02 | 3.30.70.240 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.69 | 45.0 | 5.32e-01 | 84.1% | 100.0% |
| 2oi2A02 | 3.30.70.890 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › GHMP kinase, C-terminal domain | 0.69 | 50.0 | 4.63e-01 | 75.7% | 100.0% |
| 4pwuC00 | 3.30.70.260 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain | 0.69 | 48.0 | 5.52e-01 | 84.1% | 100.0% |
| 3im8A02 | 3.30.70.250 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Malonyl-CoA ACP transacylase, ACP-binding | 0.69 | 46.0 | 5.36e-01 | 84.1% | 100.0% |
| 2diuA01 | 3.30.70.330 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain | 0.68 | 46.0 | 5.29e-01 | 72.9% | 100.0% |
| 3mahA02 | 3.30.70.260 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain | 0.68 | 43.0 | 5.09e-01 | 72.9% | 100.0% |
| 2e29A01 | 3.30.70.2280 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.67 | 45.0 | 5.19e-01 | 73.8% | 97.4% |
| 4er8A00 | 3.30.70.1290 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Transposase IS200-like | 0.67 | 52.0 | 4.55e-01 | 84.1% | 89.7% |
| 2re1A02 | 3.30.70.260 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain | 0.67 | 45.0 | 5.25e-01 | 71.0% | 100.0% |
| 2khdA00 | 3.30.70.860 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.66 | 49.0 | 4.90e-01 | 78.5% | 75.9% |
| 2kwaA00 | 3.30.1360.40 | Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › | 0.66 | 46.0 | 4.72e-01 | 71.0% | 88.1% |
| 2gqqA02 | 3.30.70.920 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Lrp/AsnC effector binding domain/regulation of amino acid metabolism (RAM) domain | 0.66 | 46.0 | 5.06e-01 | 84.1% | 89.4% |
| 2a2cA02 | 3.30.70.3170 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.66 | 50.0 | 5.52e-01 | 83.2% | 100.0% |
| 3ofgB00 | 3.30.70.260 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain | 0.66 | 51.0 | 5.55e-01 | 86.0% | 98.9% |
| 1ufwA00 | 3.30.70.330 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain | 0.66 | 49.0 | 5.13e-01 | 86.0% | 87.4% |
| 3e3xA01 | 3.30.70.870 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Elongation Factor G (Translational Gtpase), domain 3 | 0.66 | 49.0 | 4.86e-01 | 78.5% | 85.0% |
| 7qddB01 | 3.30.70.330 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain | 0.65 | 43.0 | 5.03e-01 | 73.8% | 98.6% |
| 3k17A02 | 3.30.70.890 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › GHMP kinase, C-terminal domain | 0.65 | 47.0 | 4.34e-01 | 76.6% | 100.0% |
| 1x9mA03 | 3.30.70.370 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.65 | 58.0 | 4.86e-01 | 98.1% | 87.6% |
| 1s5jA03 | 3.90.1600.10 | Alpha Beta › Alpha-Beta Complex › Palm domain of DNA polymerase › B family DNA polymerase, palm domain | 0.64 | 56.0 | 4.95e-01 | 96.3% | 94.3% |
| 1s7hA01 | 3.30.70.930 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.64 | 46.0 | 5.17e-01 | 86.0% | 100.0% |
| 3s1tA02 | 3.30.70.260 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain | 0.64 | 45.0 | 5.04e-01 | 72.9% | 100.0% |
| 1wf1A01 | 3.30.70.330 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain | 0.64 | 45.0 | 4.87e-01 | 84.1% | 87.8% |
| 3aawA02 | 3.30.2130.10 | Alpha Beta › 2-Layer Sandwich › VC0802-like › VC0802-like | 0.64 | 47.0 | 4.08e-01 | 77.6% | 78.8% |
| 4pcqA02 | 3.30.70.920 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Lrp/AsnC effector binding domain/regulation of amino acid metabolism (RAM) domain | 0.64 | 48.0 | 5.29e-01 | 79.4% | 100.0% |
| 1y10B02 | 3.30.70.1230 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain | 0.64 | 55.0 | 4.59e-01 | 94.4% | 93.4% |
| 1qd1A01 | 3.30.990.10 | Alpha Beta › 2-Layer Sandwich › Formiminotransferase-cyclodeaminase; Chain B, domain 1 › Formiminotransferase, N-terminal subdomain | 0.64 | 50.0 | 4.21e-01 | 84.1% | 99.4% |
| 1mg7A01 | 3.30.70.1000 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Switch protein XOL-1, GHMP-like | 0.63 | 55.0 | 4.69e-01 | 95.3% | 84.0% |
| 2cpdA01 | 3.30.70.330 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain | 0.63 | 43.0 | 4.95e-01 | 84.1% | 100.0% |
| 2dgtA01 | 3.30.70.330 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain | 0.63 | 42.0 | 4.92e-01 | 72.0% | 100.0% |
| 2iruA02 | 3.30.70.3300 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.63 | 49.0 | 4.54e-01 | 83.2% | 88.4% |
| 1weyA00 | 3.30.70.330 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain | 0.63 | 48.0 | 4.89e-01 | 86.9% | 82.7% |
| 2dt9A02 | 3.30.70.260 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain | 0.63 | 45.0 | 5.05e-01 | 73.8% | 100.0% |
| 4dn9B00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.63 | 45.0 | 4.74e-01 | 75.7% | 93.8% |
| 4aukA01 | 3.30.70.2810 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.63 | 44.0 | 4.95e-01 | 83.2% | 100.0% |
| 3trgA00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.62 | 47.0 | 4.94e-01 | 84.1% | 89.4% |
| 3aqoA01 | 3.30.70.3400 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.62 | 44.0 | 4.84e-01 | 72.9% | 100.0% |
| 1tuwA00 | 3.30.70.1090 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Dimeric alpha+beta barrel. | 0.62 | 49.0 | 4.94e-01 | 84.1% | 97.2% |
| 2ia0B02 | 3.30.70.920 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Lrp/AsnC effector binding domain/regulation of amino acid metabolism (RAM) domain | 0.62 | 48.0 | 4.97e-01 | 92.5% | 88.9% |
| 2kviA00 | 3.30.70.330 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain | 0.62 | 42.0 | 4.79e-01 | 75.7% | 96.1% |
| 3tviA02 | 3.30.2130.10 | Alpha Beta › 2-Layer Sandwich › VC0802-like › VC0802-like | 0.62 | 54.0 | 4.77e-01 | 97.2% | 88.7% |
| 3ossD00 | 3.30.1370.120 | Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › | 0.62 | 46.0 | 4.06e-01 | 78.5% | 86.0% |
| 2dgxA01 | 3.30.70.330 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain | 0.62 | 44.0 | 4.88e-01 | 73.8% | 100.0% |
| 2cpxA01 | 3.30.70.330 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain | 0.61 | 43.0 | 4.76e-01 | 72.0% | 100.0% |
| 1x0pA01 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.61 | 44.0 | 4.66e-01 | 75.7% | 85.4% |
| 3ungC03 | 3.30.70.270 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain | 0.61 | 48.0 | 4.51e-01 | 84.1% | 89.5% |
| 3n01A00 | 3.30.70.2470 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Protein-tyrosine phosphatase receptor IA-2 ectodomain | 0.61 | 44.0 | 4.74e-01 | 74.8% | 100.0% |
| 5yppA00 | 3.30.70.260 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain | 0.60 | 46.0 | 4.88e-01 | 82.2% | 95.6% |
| 2ifxA01 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.60 | 46.0 | 4.99e-01 | 84.1% | 100.0% |
| 2c2nA02 | 3.30.70.250 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Malonyl-CoA ACP transacylase, ACP-binding | 0.60 | 41.0 | 4.70e-01 | 75.7% | 98.7% |
| 1q5yC00 | 3.30.70.1150 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT-like. Chain A, domain 2 | 0.60 | 42.0 | 4.72e-01 | 73.8% | 97.6% |
| 1kkhA02 | 3.30.70.890 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › GHMP kinase, C-terminal domain | 0.60 | 44.0 | 4.18e-01 | 78.5% | 98.5% |
| 2okqB00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.59 | 47.0 | 4.63e-01 | 86.0% | 93.2% |
| 4uskA02 | 3.30.70.890 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › GHMP kinase, C-terminal domain | 0.59 | 49.0 | 4.36e-01 | 90.7% | 93.5% |
| 1vk8A00 | 3.30.70.930 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.59 | 47.0 | 4.96e-01 | 86.0% | 97.8% |
| 1lxjA00 | 3.30.70.930 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.58 | 46.0 | 4.76e-01 | 85.0% | 91.3% |
| 6w72A01 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.58 | 46.0 | 4.38e-01 | 86.0% | 93.1% |
| 1whvA00 | 3.30.70.330 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain | 0.58 | 40.0 | 4.18e-01 | 84.1% | 77.0% |
| 1yrxC01 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.58 | 41.0 | 4.21e-01 | 74.8% | 77.9% |
| 4erdA00 | 3.30.70.330 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain | 0.57 | 45.0 | 4.50e-01 | 85.0% | 84.3% |
| 4hacA02 | 3.30.70.890 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › GHMP kinase, C-terminal domain | 0.56 | 43.0 | 4.09e-01 | 82.2% | 73.6% |
| 1h72C02 | 3.30.70.890 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › GHMP kinase, C-terminal domain | 0.56 | 46.0 | 4.30e-01 | 90.7% | 97.0% |
| 1b24A01 | 3.10.28.10 | Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases | 0.54 | 35.0 | 3.67e-01 | 70.1% | 71.6% |
| 3c9gA01 | 3.30.1440.10 | Alpha Beta › 2-Layer Sandwich › 50s Ribosomal Protein L5; Chain: A, › Ribosomal protein L5 | 0.51 | 37.0 | 3.53e-01 | 75.7% | 84.9% |
| 1s9iB01 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.50 | 37.0 | 3.95e-01 | 84.1% | 90.3% |
ECOD (94)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4959113 | 304.3.1.0 ↗ | a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain | 0.81 | 49.0 | 6.10e-01 | 74.8% | 100.0% |
| 5029667 | 304.3.1.0 ↗ | a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain | 0.78 | 50.0 | 6.08e-01 | 76.6% | 100.0% |
| 3764453 | 304.24.1.33 ↗ | a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like › DUF4708 | 0.76 | 52.0 | 4.27e-01 | 70.1% | 100.0% |
| 5022444 | 304.24.1.0 ↗ | a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like | 0.75 | 49.0 | 5.59e-01 | 84.1% | 88.7% |
| 4939299 | 304.24.1.3 ↗ | a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like › EFG_III | 0.73 | 52.0 | 5.59e-01 | 85.0% | 86.7% |
| 4229147 | 304.120.1.6 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in ThiI › Ferredoxin-like domain in ThiI › ThiI_fer | 0.71 | 51.0 | 5.79e-01 | 74.8% | 98.8% |
| 4128792 | 304.11.1.0 ↗ | a+b two layers › Alpha-beta plaits › Probable ACP-binding domain of malonyl-CoA ACP transacylase › Probable ACP-binding domain of malonyl-CoA ACP transacylase | 0.71 | 50.0 | 5.61e-01 | 84.1% | 96.2% |
| 3356626 | 304.48.1.21 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Thg1,Thg1C | 0.71 | 55.0 | 4.77e-01 | 81.3% | 76.2% |
| 4089899 | 304.120.1.6 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in ThiI › Ferredoxin-like domain in ThiI › ThiI_fer | 0.71 | 48.0 | 5.57e-01 | 74.8% | 98.7% |
| 3381288 | 304.24.1.0 ↗ | a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like | 0.70 | 52.0 | 5.76e-01 | 86.9% | 96.5% |
| 4988706 | 304.7.1.0 ↗ | a+b two layers › Alpha-beta plaits › Protease propeptides/inhibitors › Protease propeptides/inhibitors | 0.70 | 46.0 | 5.07e-01 | 75.7% | 83.5% |
| 5079022 | 1036.1.1.1 ↗ | a+b two layers › 60S ribosomal export protein NMD3 a+b domain › 60S ribosomal export protein NMD3 a+b domain › 60S ribosomal export protein NMD3 a+b domain › NMD3 | 0.70 | 51.0 | 5.12e-01 | 76.6% | 88.2% |
| 3708065 | 304.11.1.0 ↗ | a+b two layers › Alpha-beta plaits › Probable ACP-binding domain of malonyl-CoA ACP transacylase › Probable ACP-binding domain of malonyl-CoA ACP transacylase | 0.70 | 46.0 | 5.35e-01 | 84.1% | 97.3% |
| 4200378 | 304.120.1.6 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in ThiI › Ferredoxin-like domain in ThiI › ThiI_fer | 0.70 | 48.0 | 5.55e-01 | 76.6% | 100.0% |
| 4501630 | 304.8.1.0 ↗ | a+b two layers › Alpha-beta plaits › ACT-like › ACT-like | 0.70 | 49.0 | 5.53e-01 | 78.5% | 98.8% |
| 3964348 | 304.28.1.3 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › SecD-TM1 | 0.70 | 47.0 | 5.49e-01 | 72.0% | 100.0% |
| 1036625 | 3122.1.1.1 ↗ | a+b complex topology › MESD › MESD › MESD › Mesd | 0.69 | 49.0 | 5.52e-01 | 83.2% | 100.0% |
| 3997731 | 304.24.1.0 ↗ | a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like | 0.69 | 49.0 | 5.54e-01 | 86.0% | 98.8% |
| 4950395 | 1036.1.1.1 ↗ | a+b two layers › 60S ribosomal export protein NMD3 a+b domain › 60S ribosomal export protein NMD3 a+b domain › 60S ribosomal export protein NMD3 a+b domain › NMD3 | 0.69 | 52.0 | 5.24e-01 | 79.4% | 92.7% |
| 3941725 | 304.28.1.3 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › SecD-TM1 | 0.69 | 50.0 | 5.52e-01 | 85.0% | 95.3% |
| 4416022 | 304.17.1.2 ↗ | a+b two layers › Alpha-beta plaits › N-utilization substance G protein NusG, N-terminal domain › N-utilization substance G protein NusG, N-terminal domain › Spt5-NGN | 0.69 | 50.0 | 5.46e-01 | 84.1% | 94.1% |
| 4990211 | 1036.1.1.1 ↗ | a+b two layers › 60S ribosomal export protein NMD3 a+b domain › 60S ribosomal export protein NMD3 a+b domain › 60S ribosomal export protein NMD3 a+b domain › NMD3 | 0.69 | 49.0 | 5.06e-01 | 73.8% | 94.0% |
| 4935680 | 1036.1.1.1 ↗ | a+b two layers › 60S ribosomal export protein NMD3 a+b domain › 60S ribosomal export protein NMD3 a+b domain › 60S ribosomal export protein NMD3 a+b domain › NMD3 | 0.69 | 52.0 | 5.16e-01 | 79.4% | 92.7% |
| 4947994 | 1036.1.1.0 ↗ | a+b two layers › 60S ribosomal export protein NMD3 a+b domain › 60S ribosomal export protein NMD3 a+b domain › 60S ribosomal export protein NMD3 a+b domain | 0.68 | 51.0 | 5.15e-01 | 78.5% | 96.2% |
| 3471440 | 304.24.1.3 ↗ | a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like › EFG_III | 0.68 | 50.0 | 5.53e-01 | 86.9% | 97.6% |
| 5027967 | 304.28.1.0 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain | 0.67 | 51.0 | 5.65e-01 | 85.0% | 100.0% |
| 5047234 | 304.4.1.0 ↗ | a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel | 0.67 | 55.0 | 5.79e-01 | 92.5% | 97.9% |
| 4940473 | 304.28.1.0 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain | 0.67 | 53.0 | 5.69e-01 | 88.8% | 100.0% |
| 5030091 | 304.19.1.1 ↗ | a+b two layers › Alpha-beta plaits › eIF-2-alpha, C-terminal domain › eIF-2-alpha, C-terminal domain › EIF_2_alpha | 0.67 | 48.0 | 5.34e-01 | 74.8% | 100.0% |
| 3215476 | 304.120.1.0 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in ThiI › Ferredoxin-like domain in ThiI | 0.67 | 48.0 | 4.93e-01 | 73.8% | 100.0% |
| 3856783 | 304.7.1.23 ↗ | a+b two layers › Alpha-beta plaits › Protease propeptides/inhibitors › Protease propeptides/inhibitors › DUF4708 | 0.67 | 49.0 | 5.43e-01 | 85.0% | 97.6% |
| 4184602 | 304.128.1.0 ↗ | a+b two layers › Alpha-beta plaits › ferredoxin-like domain in periplasmic region of MacB › ferredoxin-like domain in periplasmic region of MacB | 0.67 | 51.0 | 5.58e-01 | 80.4% | 95.6% |
| 3961033 | 304.154.1.1 ↗ | a+b two layers › Alpha-beta plaits › Regulator of polyketide synthase expression N-terminal domain › Regulator of polyketide synthase expression N-terminal domain › GGDEF_2 | 0.66 | 58.0 | 5.08e-01 | 96.3% | 77.5% |
| 3603014 | 304.28.1.4 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › SecD_1st | 0.66 | 48.0 | 5.28e-01 | 76.6% | 98.8% |
| 4682115 | 304.28.1.4 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › SecD_1st | 0.66 | 48.0 | 5.13e-01 | 75.7% | 92.2% |
| 4945702 | 304.17.1.3 ↗ | a+b two layers › Alpha-beta plaits › N-utilization substance G protein NusG, N-terminal domain › N-utilization substance G protein NusG, N-terminal domain › KOW | 0.66 | 48.0 | 5.34e-01 | 82.2% | 96.5% |
| 5023065 | 304.28.1.4 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › SecD_1st | 0.66 | 48.0 | 5.24e-01 | 77.6% | 96.5% |
| 5028999 | 304.4.1.0 ↗ | a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel | 0.66 | 52.0 | 5.38e-01 | 89.7% | 89.0% |
| 3617015 | 304.120.1.12 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in ThiI › Ferredoxin-like domain in ThiI › PF26955 | 0.66 | 49.0 | 5.43e-01 | 88.8% | 100.0% |
| 3914432 | 304.11.1.13 ↗ | a+b two layers › Alpha-beta plaits › Probable ACP-binding domain of malonyl-CoA ACP transacylase › Probable ACP-binding domain of malonyl-CoA ACP transacylase › DUF4708 | 0.66 | 49.0 | 4.17e-01 | 79.4% | 48.9% |
| 3672141 | 304.162.1.0 ↗ | a+b two layers › Alpha-beta plaits › Competence or damage-inducible protein CinA middle domain › Competence or damage-inducible protein CinA middle domain | 0.66 | 42.0 | 5.02e-01 | 70.1% | 100.0% |
| 5036213 | 304.4.1.0 ↗ | a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel | 0.65 | 47.0 | 5.04e-01 | 75.7% | 87.8% |
| 4073171 | 304.120.1.11 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in ThiI › Ferredoxin-like domain in ThiI › UreE_C | 0.65 | 48.0 | 5.02e-01 | 89.7% | 86.3% |
| 4246202 | 304.56.1.6 ↗ | a+b two layers › Alpha-beta plaits › CRISPR associated protein Cas2-like › CRISPR associated protein Cas2-like › UreE_C | 0.65 | 48.0 | 5.02e-01 | 89.7% | 86.3% |
| 3892177 | 304.9.1.104 ↗ | a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_PARP14_2 | 0.65 | 51.0 | 5.55e-01 | 87.9% | 100.0% |
| 3626328 | 304.117.1.1 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in YebC › Ferredoxin-like domain in YebC › Transcrip_reg | 0.65 | 46.0 | 5.24e-01 | 88.8% | 100.0% |
| 4523274 | 304.24.1.1 ↗ | a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like › EFG_C | 0.64 | 53.0 | 4.27e-01 | 86.9% | 50.8% |
| 3970823 | 304.24.1.0 ↗ | a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like | 0.64 | 49.0 | 5.30e-01 | 85.0% | 95.6% |
| 4267064 | 304.24.1.3 ↗ | a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like › EFG_III | 0.64 | 49.0 | 5.30e-01 | 85.0% | 95.6% |
| 3370992 | 304.48.1.21 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Thg1,Thg1C | 0.64 | 55.0 | 3.59e-01 | 92.5% | 77.8% |
| 5012335 | 304.4.1.29 ↗ | a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › AsnC_trans_reg_3 | 0.64 | 48.0 | 4.85e-01 | 84.1% | 79.0% |
| 3742864 | 304.8.1.0 ↗ | a+b two layers › Alpha-beta plaits › ACT-like › ACT-like | 0.64 | 45.0 | 4.53e-01 | 79.4% | 71.8% |
| 3719744 | 304.24.1.0 ↗ | a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like | 0.64 | 50.0 | 5.35e-01 | 86.0% | 97.8% |
| 3612286 | 304.9.1.1 ↗ | a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 | 0.64 | 48.0 | 4.88e-01 | 79.4% | 90.5% |
| 3955607 | 304.4.1.4 ↗ | a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › ABM | 0.64 | 51.0 | 5.29e-01 | 86.0% | 100.0% |
| 5068256 | 304.17.1.2 ↗ | a+b two layers › Alpha-beta plaits › N-utilization substance G protein NusG, N-terminal domain › N-utilization substance G protein NusG, N-terminal domain › Spt5-NGN | 0.63 | 47.0 | 5.13e-01 | 84.1% | 98.8% |
| 3959043 | 862.1.1.0 ↗ | a+b complex topology › Prim-pol domain › Prim-pol domain › Prim-pol domain | 0.63 | 54.0 | 3.87e-01 | 94.4% | 63.4% |
| 3857454 | 246.3.1.0 ↗ | a+b four layers › Carbon-nitrogen hydrolase-like › DNase I-like › DNase I-like | 0.63 | 46.0 | 2.98e-01 | 75.7% | 16.6% |
| 3521768 | 304.9.1.1 ↗ | a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 | 0.63 | 46.0 | 4.97e-01 | 77.6% | 93.3% |
| 3471727 | 304.9.1.1 ↗ | a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 | 0.63 | 45.0 | 4.94e-01 | 75.7% | 100.0% |
| 3397461 | 304.11.1.0 ↗ | a+b two layers › Alpha-beta plaits › Probable ACP-binding domain of malonyl-CoA ACP transacylase › Probable ACP-binding domain of malonyl-CoA ACP transacylase | 0.63 | 44.0 | 4.88e-01 | 73.8% | 98.8% |
| 4975915 | 304.4.1.29 ↗ | a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › AsnC_trans_reg_3 | 0.62 | 48.0 | 5.19e-01 | 86.0% | 96.7% |
| 3922561 | 304.9.1.0 ↗ | a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD | 0.62 | 48.0 | 4.98e-01 | 81.3% | 89.0% |
| 4266108 | 304.9.1.0 ↗ | a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD | 0.62 | 44.0 | 4.65e-01 | 73.8% | 88.4% |
| 3622719 | 304.9.1.69 ↗ | a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RBD_DGKtheta | 0.62 | 47.0 | 4.89e-01 | 86.0% | 87.0% |
| 5060071 | 304.17.1.2 ↗ | a+b two layers › Alpha-beta plaits › N-utilization substance G protein NusG, N-terminal domain › N-utilization substance G protein NusG, N-terminal domain › Spt5-NGN | 0.62 | 48.0 | 4.56e-01 | 84.1% | 94.6% |
| 3597389 | 304.9.1.0 ↗ | a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD | 0.62 | 49.0 | 4.81e-01 | 84.1% | 81.6% |
| 3947003 | 304.4.1.1 ↗ | a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › AsnC_trans_reg | 0.62 | 49.0 | 5.20e-01 | 89.7% | 95.8% |
| 3947510 | 304.4.1.1 ↗ | a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › AsnC_trans_reg | 0.61 | 48.0 | 5.09e-01 | 87.9% | 93.7% |
| 4947980 | 304.4.1.0 ↗ | a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel | 0.61 | 50.0 | 5.18e-01 | 89.7% | 93.0% |
| 3269719 | 304.8.1.54 ↗ | a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › ACT_13 | 0.61 | 49.0 | 4.94e-01 | 87.9% | 87.6% |
| 162430 | 304.9.1.17 ↗ | a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › DUF1866 | 0.61 | 44.0 | 4.69e-01 | 76.6% | 89.0% |
| 5046142 | 304.4.1.0 ↗ | a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel | 0.61 | 49.0 | 5.21e-01 | 86.9% | 96.8% |
| 5073826 | 304.4.1.29 ↗ | a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › AsnC_trans_reg_3 | 0.61 | 47.0 | 4.95e-01 | 86.0% | 91.6% |
| 3475064 | 304.9.1.0 ↗ | a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD | 0.61 | 43.0 | 4.12e-01 | 73.8% | 74.4% |
| 3908982 | 304.9.1.1 ↗ | a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 | 0.61 | 48.0 | 4.85e-01 | 86.0% | 85.7% |
| 4979323 | 304.4.1.0 ↗ | a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel | 0.61 | 46.0 | 4.98e-01 | 84.1% | 94.4% |
| 4970769 | 304.4.1.0 ↗ | a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel | 0.60 | 50.0 | 5.14e-01 | 89.7% | 94.0% |
| 3974796 | 304.4.1.1 ↗ | a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › AsnC_trans_reg | 0.60 | 48.0 | 4.94e-01 | 89.7% | 90.0% |
| 3974171 | 304.4.1.1 ↗ | a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › AsnC_trans_reg | 0.60 | 46.0 | 4.97e-01 | 86.9% | 96.7% |
| 3841538 | 304.9.1.0 ↗ | a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD | 0.60 | 48.0 | 4.97e-01 | 84.1% | 91.0% |
| 3531239 | 304.151.1.1 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin-like domain of receptor-type protein tyrosine phosphatase › Ferredoxin-like domain of receptor-type protein tyrosine phosphatase › Receptor_IA-2 | 0.60 | 47.0 | 4.99e-01 | 85.0% | 98.9% |
| 3621644 | 327.11.2.1 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) › KH_1 | 0.60 | 43.0 | 4.50e-01 | 76.6% | 81.0% |
| 4956754 | 304.19.1.1 ↗ | a+b two layers › Alpha-beta plaits › eIF-2-alpha, C-terminal domain › eIF-2-alpha, C-terminal domain › EIF_2_alpha | 0.60 | 47.0 | 4.97e-01 | 84.1% | 96.8% |
| 4019157 | 304.26.1.1 ↗ | a+b two layers › Alpha-beta plaits › MTH1187/YkoF-like › MTH1187/YkoF-like › Thiamine_BP | 0.59 | 47.0 | 4.77e-01 | 85.0% | 87.0% |
| 4602676 | 304.110.1.4 ↗ | a+b two layers › Alpha-beta plaits › Acylphosphatase-like › Acylphosphatase-like › UPF0176_N | 0.59 | 44.0 | 4.65e-01 | 79.4% | 100.0% |
| 5031028 | 304.4.1.0 ↗ | a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel | 0.59 | 50.0 | 4.99e-01 | 92.5% | 89.1% |
| 3972957 | 5104.1.1.0 ↗ | a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases | 0.57 | 42.0 | 3.88e-01 | 75.7% | 70.4% |
| 4133574 | 304.110.1.4 ↗ | a+b two layers › Alpha-beta plaits › Acylphosphatase-like › Acylphosphatase-like › UPF0176_N | 0.57 | 43.0 | 4.41e-01 | 79.4% | 96.0% |
| 3941868 | 5104.1.1.1 ↗ | a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › DHHA1 | 0.57 | 42.0 | 3.86e-01 | 75.7% | 70.4% |
| 3420784 | 304.9.1.0 ↗ | a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD | 0.56 | 46.0 | 4.69e-01 | 93.5% | 91.4% |
| 3266889 | 304.9.1.81 ↗ | a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RBD_AKAP-17A | 0.56 | 44.0 | 3.93e-01 | 84.1% | 66.7% |
| 4224238 | 210.1.3.4 ↗ | a+b four layers › Ntn/PP2C › Ntn › Class II glutamine amidotransferases › GATase_6 | 0.55 | 38.0 | 3.03e-01 | 70.1% | 93.0% |
| 3425660 | 304.9.1.0 ↗ | a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD | 0.54 | 42.0 | 4.33e-01 | 86.9% | 91.0% |
D6
medium
residues 618-677
Domain cluster:
representative
CATH (57)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2yx8A00 | 1.10.150.510 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Receptor activity modifying family | 0.81 | 69.0 | 6.19e-01 | 93.3% | 81.5% |
| 1ls1A01 | 1.20.120.140 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › SRP54, nucleotide-binding domain | 0.77 | 58.0 | 5.05e-01 | 80.0% | 56.2% |
| 3fbzA01 | 1.20.58.800 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.77 | 63.0 | 5.33e-01 | 93.3% | 55.9% |
| 4v1gA00 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.76 | 54.0 | 4.82e-01 | 76.7% | 52.9% |
| 2btdA00 | 1.25.40.340 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › DhaL domain | 0.73 | 62.0 | 4.26e-01 | 96.7% | 38.8% |
| 3bemB00 | 3.40.109.10 | Alpha Beta › 3-Layer(aba) Sandwich › NADH Oxidase › NADH Oxidase | 0.73 | 54.0 | 3.68e-01 | 80.0% | 37.8% |
| 4hiaA00 | 3.30.450.20 | Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain | 0.72 | 54.0 | 3.84e-01 | 80.0% | 43.2% |
| 1zmbA02 | 6.10.170.10 | Special › Helix non-globular › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › | 0.72 | 44.0 | 5.07e-01 | 73.3% | 100.0% |
| 4okvE00 | 6.10.140.1890 | Special › Helix non-globular › Helix Hairpins › | 0.72 | 51.0 | 5.05e-01 | 76.7% | 90.8% |
| 1yzbA02 | 1.10.287.10 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › S15/NS1, RNA-binding | 0.71 | 47.0 | 5.11e-01 | 71.7% | 89.1% |
| 4kb2A01 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.70 | 52.0 | 4.33e-01 | 81.7% | 77.1% |
| 2f4qA02 | 1.10.132.120 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › | 0.69 | 57.0 | 4.47e-01 | 93.3% | 43.3% |
| 4dmvA01 | 1.20.58.1190 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.69 | 52.0 | 4.60e-01 | 80.0% | 64.7% |
| 2nn4A00 | 1.10.287.760 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YqgQ-like | 0.69 | 49.0 | 4.86e-01 | 93.3% | 72.6% |
| 1j8yF01 | 1.20.120.140 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › SRP54, nucleotide-binding domain | 0.69 | 50.0 | 4.46e-01 | 78.3% | 55.8% |
| 2rldA00 | 1.20.1440.60 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence | 0.67 | 48.0 | 3.87e-01 | 80.0% | 39.5% |
| 2om6A02 | 1.10.150.400 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › | 0.67 | 52.0 | 4.84e-01 | 86.7% | 68.4% |
| 3nivC02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.67 | 58.0 | 4.58e-01 | 96.7% | 90.3% |
| 2k19A00 | 1.20.1440.140 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.67 | 54.0 | 4.61e-01 | 91.7% | 55.1% |
| 1w0bA01 | 1.20.58.420 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › AHSP | 0.67 | 56.0 | 4.91e-01 | 95.0% | 78.3% |
| 1t98A01 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.66 | 54.0 | 4.88e-01 | 93.3% | 66.7% |
| 6qumQ00 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.65 | 46.0 | 4.39e-01 | 76.7% | 64.9% |
| 2d2sA02 | 1.20.58.1220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Exo84p, C-terminal helical domain | 0.65 | 55.0 | 4.68e-01 | 96.7% | 68.3% |
| 1y7oB00 | 3.90.226.10 | Alpha Beta › Alpha-Beta Complex › 2-enoyl-CoA Hydratase; Chain A, domain 1 › 2-enoyl-CoA Hydratase; Chain A, domain 1 | 0.64 | 58.0 | 4.09e-01 | 100.0% | 54.5% |
| 4wqoD00 | 1.20.1310.10 | Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats | 0.64 | 53.0 | 4.22e-01 | 100.0% | 83.7% |
| 4o6yB00 | 1.20.120.1770 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.64 | 55.0 | 3.83e-01 | 100.0% | 66.4% |
| 2h7fX02 | 3.90.15.10 | Alpha Beta › Alpha-Beta Complex › Topoisomerase I; Chain A, domain 3 › Topoisomerase I; Chain A, domain 3 | 0.63 | 52.0 | 3.51e-01 | 95.0% | 76.3% |
| 1cbyA00 | 3.40.198.10 | Alpha Beta › 3-Layer(aba) Sandwich › Delta-endotoxin CytB › Delta-endotoxin CytB-like | 0.63 | 50.0 | 3.43e-01 | 90.0% | 48.9% |
| 2iw3A02 | 1.20.1390.20 | Mainly Alpha › Up-down Bundle › PWI domain › | 0.63 | 49.0 | 4.34e-01 | 93.3% | 58.9% |
| 1b0bA00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.62 | 51.0 | 3.96e-01 | 93.3% | 87.2% |
| 3l1nA01 | 6.10.140.790 | Special › Helix non-globular › Helix Hairpins › | 0.62 | 44.0 | 4.75e-01 | 76.7% | 88.2% |
| 2rn7A01 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.62 | 45.0 | 4.41e-01 | 91.7% | 71.2% |
| 3zdmB00 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.61 | 46.0 | 4.82e-01 | 95.0% | 100.0% |
| 3hugA00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.61 | 44.0 | 4.06e-01 | 78.3% | 80.0% |
| 3umgA02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.61 | 50.0 | 4.79e-01 | 93.3% | 90.1% |
| 3tahA02 | 1.10.287.1770 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.60 | 49.0 | 4.35e-01 | 90.0% | 80.7% |
| 3umcD02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.60 | 48.0 | 4.51e-01 | 93.3% | 78.2% |
| 4asvA00 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.59 | 46.0 | 4.25e-01 | 98.3% | 64.6% |
| 2oqoA00 | 1.10.3810.10 | Mainly Alpha › Orthogonal Bundle › Penicillin binding protein transpeptidase fold › Biosynthetic peptidoglycan transglycosylase-like | 0.59 | 49.0 | 3.60e-01 | 98.3% | 93.9% |
| 4l7nA01 | 1.20.142.10 | Mainly Alpha › Up-down Bundle › Poly(ADP-ribose) Polymerase; domain 1 › Poly(ADP-ribose) polymerase, regulatory domain | 0.58 | 44.0 | 3.35e-01 | 81.7% | 55.2% |
| 1j09A05 | 1.10.10.350 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › | 0.58 | 42.0 | 3.58e-01 | 76.7% | 52.0% |
| 6o9aA01 | 3.40.190.10 | Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II | 0.58 | 51.0 | 3.83e-01 | 100.0% | 83.4% |
| 2wmmA01 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.58 | 43.0 | 4.70e-01 | 78.3% | 95.9% |
| 4o1jA00 | 3.40.1050.10 | Alpha Beta › 3-Layer(aba) Sandwich › Beta-carbonic Anhydrase; Chain A › Carbonic anhydrase | 0.57 | 50.0 | 3.48e-01 | 98.3% | 65.0% |
| 1t7sA00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.57 | 43.0 | 3.38e-01 | 80.0% | 38.8% |
| 4jgwA01 | 1.20.870.10 | Mainly Alpha › Up-down Bundle › Son of sevenless (SoS) protein; Chain S, domain 1 › Son of sevenless (SoS) protein Chain: S domain 1 | 0.57 | 48.0 | 3.69e-01 | 100.0% | 57.1% |
| 5xdcB01 | 1.10.540.10 | Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain | 0.56 | 45.0 | 3.81e-01 | 93.3% | 58.6% |
| 1qsdA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.56 | 49.0 | 4.10e-01 | 98.3% | 97.1% |
| 2avuB00 | 1.10.4000.10 | Mainly Alpha › Orthogonal Bundle › Flagellar transcriptional activator fold › Flagellar transcriptional activator FlhD | 0.55 | 37.0 | 3.18e-01 | 70.0% | 64.4% |
| 1ed1A00 | 1.10.150.90 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Immunodeficiency lentiviruses, gag gene matrix protein p17 | 0.55 | 49.0 | 3.95e-01 | 100.0% | 59.6% |
| 4g80T00 | 1.20.120.350 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C | 0.54 | 46.0 | 3.61e-01 | 98.3% | 69.1% |
| 2kw6A00 | 6.10.140.1300 | Special › Helix non-globular › Helix Hairpins › | 0.54 | 42.0 | 4.14e-01 | 86.7% | 81.5% |
| 1bhaA00 | 1.10.287.170 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.54 | 43.0 | 4.15e-01 | 85.0% | 77.6% |
| 5a2gA00 | 3.40.50.1820 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain | 0.54 | 44.0 | 2.65e-01 | 95.0% | 42.5% |
| 1l5jA03 | 3.40.1060.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aconitase; Domain 2 › Aconitase, Domain 2 | 0.53 | 43.0 | 3.27e-01 | 98.3% | 36.4% |
| 2n5fA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.52 | 45.0 | 3.64e-01 | 100.0% | 78.9% |
| 3k3oA02 | 1.20.58.1360 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.51 | 43.0 | 3.88e-01 | 93.3% | 79.8% |
ECOD (61)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3691750 | 376.1.1.8 ↗ | few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box › U-box | 0.84 | 60.0 | 4.37e-01 | 75.0% | 39.6% |
| 3392260 | 6026.1.1.0 ↗ | alpha duplicates or obligate multimers › cwf21 domain › cwf21 domain › cwf21 domain | 0.83 | 57.0 | 5.43e-01 | 73.3% | 61.4% |
| 3312745 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.82 | 61.0 | 4.38e-01 | 78.3% | 30.0% |
| 3958294 | 181.1.1.0 ↗ | alpha bundles › Domain of the SRP/SRP receptor G proteins-like › Domain of the SRP/SRP receptor G-proteins › Domain of the SRP/SRP receptor G-proteins | 0.82 | 62.0 | 5.34e-01 | 80.0% | 53.3% |
| 3825200 | 181.1.1.0 ↗ | alpha bundles › Domain of the SRP/SRP receptor G proteins-like › Domain of the SRP/SRP receptor G-proteins › Domain of the SRP/SRP receptor G-proteins | 0.80 | 58.0 | 4.95e-01 | 81.7% | 48.4% |
| 4316366 | 1037.1.1.1 ↗ | alpha bundles › Prolipoprotein diacylglyceryl transferase › Prolipoprotein diacylglyceryl transferase › Prolipoprotein diacylglyceryl transferase › LGT | 0.80 | 60.0 | 4.08e-01 | 80.0% | 34.5% |
| 3287859 | 106.1.1.11 ↗ | alpha arrays › Globin-like › Globin-like › Globin-like › RsbRD_N | 0.80 | 59.0 | 4.76e-01 | 80.0% | 83.5% |
| 3603904 | 181.1.1.1 ↗ | alpha bundles › Domain of the SRP/SRP receptor G proteins-like › Domain of the SRP/SRP receptor G-proteins › Domain of the SRP/SRP receptor G-proteins › SRP54_N | 0.79 | 58.0 | 5.07e-01 | 78.3% | 52.2% |
| 4932398 | 181.1.1.1 ↗ | alpha bundles › Domain of the SRP/SRP receptor G proteins-like › Domain of the SRP/SRP receptor G-proteins › Domain of the SRP/SRP receptor G-proteins › SRP54_N | 0.79 | 58.0 | 5.17e-01 | 78.3% | 55.3% |
| 5025487 | 7574.1.1.0 ↗ | a/b three-layered sandwiches › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) › Thiamin diphosphate-binding fold (THDP-binding) | 0.79 | 53.0 | 3.94e-01 | 75.0% | 28.0% |
| 3988991 | 181.1.1.1 ↗ | alpha bundles › Domain of the SRP/SRP receptor G proteins-like › Domain of the SRP/SRP receptor G-proteins › Domain of the SRP/SRP receptor G-proteins › SRP54_N | 0.79 | 59.0 | 5.14e-01 | 80.0% | 53.3% |
| 4348932 | 5069.1.3.1 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › Sdh_cyt | 0.78 | 59.0 | 4.68e-01 | 81.7% | 73.3% |
| 3478654 | 3567.1.1.103 ↗ | a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer › PBC | 0.78 | 56.0 | 4.33e-01 | 76.7% | 49.2% |
| 4943201 | 181.1.1.32 ↗ | alpha bundles › Domain of the SRP/SRP receptor G proteins-like › Domain of the SRP/SRP receptor G-proteins › Domain of the SRP/SRP receptor G-proteins › SRP54 | 0.76 | 56.0 | 4.96e-01 | 78.3% | 55.3% |
| 5066143 | 5041.1.1.0 ↗ | extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C | 0.76 | 54.0 | 5.01e-01 | 75.0% | 60.0% |
| 4248372 | 1037.1.1.1 ↗ | alpha bundles › Prolipoprotein diacylglyceryl transferase › Prolipoprotein diacylglyceryl transferase › Prolipoprotein diacylglyceryl transferase › LGT | 0.76 | 56.0 | 3.57e-01 | 80.0% | 22.7% |
| 5043220 | 181.1.1.1 ↗ | alpha bundles › Domain of the SRP/SRP receptor G proteins-like › Domain of the SRP/SRP receptor G-proteins › Domain of the SRP/SRP receptor G-proteins › SRP54_N | 0.76 | 57.0 | 5.03e-01 | 80.0% | 56.5% |
| 3925672 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.75 | 62.0 | 5.69e-01 | 93.3% | 70.0% |
| 3261624 | 3470.1.1.0 ↗ | extended segments › Glycophorin-A transmembrane domain › Glycophorin-A transmembrane domain › Glycophorin-A transmembrane domain | 0.75 | 52.0 | 5.61e-01 | 71.7% | 88.0% |
| 3835982 | 181.1.1.1 ↗ | alpha bundles › Domain of the SRP/SRP receptor G proteins-like › Domain of the SRP/SRP receptor G-proteins › Domain of the SRP/SRP receptor G-proteins › SRP54_N | 0.74 | 54.0 | 4.68e-01 | 78.3% | 49.5% |
| 4518433 | 181.1.1.1 ↗ | alpha bundles › Domain of the SRP/SRP receptor G proteins-like › Domain of the SRP/SRP receptor G-proteins › Domain of the SRP/SRP receptor G-proteins › SRP54_N | 0.74 | 63.0 | 5.48e-01 | 93.3% | 88.9% |
| 3589830 | 5043.2.1.8 ↗ | extended segments › Sensor proteins transmembrane domains › NarQ transmembrane domain › NarQ transmembrane domain › DUF5592 | 0.74 | 51.0 | 4.95e-01 | 75.0% | 67.1% |
| 4947351 | 601.33.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › CHAD domain › CHAD domain | 0.73 | 54.0 | 3.88e-01 | 80.0% | 50.3% |
| 3368602 | 101.35.1.0 ↗ | alpha arrays › HTH › DNA repair regulatory protein RecX › DNA repair regulatory protein RecX | 0.73 | 60.0 | 5.04e-01 | 93.3% | 92.4% |
| 4768204 | 101.8.1.2 ↗ | alpha arrays › HTH › An anticodon-binding domain of class I aminoacyl-tRNA synthetases › An anticodon-binding domain of class I aminoacyl-tRNA synthetases › Anticodon_2 | 0.71 | 51.0 | 3.96e-01 | 91.7% | 33.6% |
| 3615624 | 101.11.1.0 ↗ | alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 | 0.71 | 59.0 | 4.94e-01 | 91.7% | 64.8% |
| 3660653 | 101.11.1.10 ↗ | alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PF26576 | 0.70 | 58.0 | 4.79e-01 | 93.3% | 83.6% |
| 3169602 | 387.1.6.2 ↗ | few secondary structure elements › omega toxin-like › omega toxin-related › Conotoxin Mo3964 › Sin3a_C | 0.70 | 59.0 | 3.88e-01 | 98.3% | 21.9% |
| 3346926 | 148.1.3.0 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain | 0.69 | 46.0 | 4.99e-01 | 88.3% | 82.0% |
| 4138504 | 310.2.1.1 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF › RRF | 0.69 | 55.0 | 4.00e-01 | 91.7% | 88.1% |
| 3383195 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.69 | 56.0 | 3.84e-01 | 91.7% | 25.0% |
| 4558118 | 131.2.1.3 ↗ | alpha complex topology › PDEase-like › Poly A polymerase C-terminal region-like › Poly A polymerase C-terminal region-like › PolyA_pol_RNAbd | 0.69 | 59.0 | 3.76e-01 | 93.3% | 23.6% |
| 3396665 | 101.1.1.112 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › MADF_DNA_bdg | 0.69 | 56.0 | 4.81e-01 | 93.3% | 56.8% |
| 3787094 | 601.1.1.142 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Peptidase_S64, PF30502 | 0.68 | 57.0 | 4.10e-01 | 95.0% | 73.9% |
| 3436690 | 181.1.1.1 ↗ | alpha bundles › Domain of the SRP/SRP receptor G proteins-like › Domain of the SRP/SRP receptor G-proteins › Domain of the SRP/SRP receptor G-proteins › SRP54_N | 0.67 | 57.0 | 5.01e-01 | 95.0% | 88.9% |
| 5060704 | 371.1.1.5 ↗ | few secondary structure elements › Phospholipase A2, PLA2 › Phospholipase A2, PLA2 › Phospholipase A2, PLA2 › DUF1353 | 0.67 | 57.0 | 4.77e-01 | 100.0% | 93.6% |
| 4944037 | 10.1.2.0 ↗ | beta sandwiches › jelly-roll › Concanavalin A-like › GOLD domain-like (DEPRECATED) | 0.66 | 55.0 | 4.17e-01 | 95.0% | 61.3% |
| None | — | 0.64 | 53.0 | 3.74e-01 | 95.0% | 53.7% | |
| 3887051 | 101.1.1.112 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › MADF_DNA_bdg | 0.64 | 50.0 | 4.51e-01 | 91.7% | 60.0% |
| 3391717 | 101.1.1.112 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › MADF_DNA_bdg | 0.64 | 51.0 | 4.54e-01 | 93.3% | 61.1% |
| 3393185 | 101.1.1.112 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › MADF_DNA_bdg | 0.63 | 49.0 | 4.25e-01 | 93.3% | 53.0% |
| 3227148 | 196.1.1.1 ↗ | alpha bundles › Regulator of G-protein signaling, RGS › Regulator of G-protein signaling, RGS › Regulator of G-protein signaling, RGS › RGS | 0.63 | 54.0 | 4.10e-01 | 100.0% | 61.3% |
| 3171699 | 101.1.1.133 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › Vhr1 | 0.62 | 50.0 | 4.31e-01 | 93.3% | 57.0% |
| 3838401 | 192.10.1.0 ↗ | alpha bundles › Long alpha-hairpin › DnaK suppressor protein DksA, alpha-hairpin domain › DnaK suppressor protein DksA, alpha-hairpin domain | 0.62 | 49.0 | 4.30e-01 | 93.3% | 56.0% |
| 3314172 | 609.1.1.1 ↗ | alpha bundles › Domain of poly(ADP-ribose) polymerase › Domain of poly(ADP-ribose) polymerase › Domain of poly(ADP-ribose) polymerase › PARP_reg | 0.62 | 48.0 | 3.64e-01 | 98.3% | 34.2% |
| 4013953 | 101.1.8.0 ↗ | alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes | 0.62 | 50.0 | 4.54e-01 | 93.3% | 90.6% |
| 3963136 | 3317.1.1.0 ↗ | alpha arrays › KorB C-terminal domain-like › KorB C-terminal domain › KorB C-terminal domain | 0.62 | 50.0 | 3.90e-01 | 93.3% | 41.4% |
| 3258522 | 601.48.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › vWA2 C-terminal domain › vWA2 C-terminal domain | 0.61 | 47.0 | 4.64e-01 | 93.3% | 78.5% |
| 3776363 | 873.1.1.5 ↗ | a+b complex topology › H-NOX domain › H-NOX domain › H-NOX domain › HNOB | 0.60 | 51.0 | 3.47e-01 | 95.0% | 27.9% |
| 3222238 | 101.1.2.649 ↗ | alpha arrays › HTH › HTH › winged helix domain › PF28730 | 0.59 | 47.0 | 4.55e-01 | 93.3% | 77.1% |
| 4981678 | 1075.5.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter | 0.59 | 51.0 | 3.37e-01 | 100.0% | 57.7% |
| 4236831 | 604.6.1.50 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › DUF2524 | 0.59 | 49.0 | 4.44e-01 | 91.7% | 83.7% |
| 3170802 | 101.1.1.133 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › Vhr1 | 0.58 | 49.0 | 4.21e-01 | 95.0% | 61.1% |
| 1122242 | 235.1.1.5 ↗ | a+b complex topology › Lysozyme-like › Lysozyme-like › Lysozyme-like › Transgly | 0.57 | 50.0 | 4.24e-01 | 100.0% | 87.1% |
| 3433168 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.56 | 49.0 | 3.47e-01 | 98.3% | 51.4% |
| 4358621 | 604.9.1.1 ↗ | alpha bundles › Spectrin repeat-like › Ribosomal protein S20 › Ribosomal protein S20 › Ribosomal_S20p | 0.56 | 49.0 | 4.47e-01 | 98.3% | 75.9% |
| 3946728 | 148.1.3.0 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain | 0.56 | 43.0 | 3.76e-01 | 86.7% | 54.0% |
| 3571073 | 633.12.1.11 ↗ | alpha bundles › Bromodomain-like › Ta0600-like › Ta0600-like › TRP_2 | 0.55 | 45.0 | 3.94e-01 | 93.3% | 94.7% |
| 3619724 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.55 | 46.0 | 3.91e-01 | 93.3% | 72.0% |
| 3841317 | 605.1.1.337 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › TRP_2 | 0.54 | 45.0 | 3.70e-01 | 98.3% | 71.7% |
| 3684605 | 109.58.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › DNA repair protein Rev1 C-terminal domain › DNA repair protein Rev1 C-terminal domain | 0.54 | 44.0 | 3.70e-01 | 100.0% | 84.0% |
D7
medium
residues 702-757
Domain cluster:
representative
CATH (23)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2aj6A00 | 3.40.630.30 | Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) | 0.76 | 53.0 | 4.10e-01 | 73.2% | 40.8% |
| 2of7A02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.70 | 60.0 | 4.49e-01 | 96.4% | 80.7% |
| 3weeB02 | 3.30.420.40 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain | 0.67 | 48.0 | 3.71e-01 | 76.8% | 74.6% |
| 2ymmA02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.65 | 50.0 | 4.69e-01 | 96.4% | 67.1% |
| 1ea0A02 | 3.20.20.70 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I | 0.65 | 55.0 | 3.43e-01 | 100.0% | 52.0% |
| 2no4A02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.64 | 51.0 | 4.75e-01 | 92.9% | 70.7% |
| 3b0bB00 | 1.10.20.10 | Mainly Alpha › Orthogonal Bundle › Histone, subunit A › Histone, subunit A | 0.63 | 48.0 | 4.10e-01 | 92.9% | 49.5% |
| 2oyyA00 | 6.10.80.10 | Special › Helix non-globular › DNA polymerase; domain 1 › Hexameric tyrosine-coordinated heme protein (HTHP) | 0.63 | 46.0 | 4.30e-01 | 78.6% | 87.3% |
| 2zy9A03 | 1.10.357.20 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › SLC41 divalent cation transporters, integral membrane domain | 0.62 | 51.0 | 3.74e-01 | 100.0% | 80.5% |
| 3b0cW00 | 1.10.20.10 | Mainly Alpha › Orthogonal Bundle › Histone, subunit A › Histone, subunit A | 0.61 | 48.0 | 4.47e-01 | 91.1% | 86.3% |
| 3fixA00 | 3.40.630.30 | Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) | 0.60 | 43.0 | 3.20e-01 | 80.4% | 28.5% |
| 4ixjA01 | 3.30.1300.80 | Alpha Beta › 2-Layer Sandwich › Pantoate--beta-alanine Ligase; Chain: A,domain 2 › | 0.60 | 46.0 | 4.20e-01 | 87.5% | 71.4% |
| 2kg7B00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.59 | 43.0 | 3.72e-01 | 82.1% | 52.6% |
| 3dsbA01 | 3.40.630.30 | Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) | 0.59 | 41.0 | 3.47e-01 | 75.0% | 44.6% |
| 4i8oA03 | 1.10.8.1130 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Bacterial toxin RNase RnlA/LsoA, C-terminal Dmd-binding domain | 0.57 | 43.0 | 4.16e-01 | 100.0% | 73.1% |
| 1w0bA01 | 1.20.58.420 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › AHSP | 0.56 | 44.0 | 3.75e-01 | 85.7% | 57.6% |
| 1eljA02 | 3.40.190.10 | Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II | 0.56 | 45.0 | 3.16e-01 | 91.1% | 67.4% |
| 5jazA03 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.55 | 49.0 | 4.16e-01 | 100.0% | 63.7% |
| 2jbrA01 | 1.10.540.10 | Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain | 0.54 | 38.0 | 3.16e-01 | 83.9% | 37.8% |
| 4evxA00 | 1.10.1740.240 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › | 0.54 | 42.0 | 3.76e-01 | 98.2% | 84.5% |
| 3clqA03 | 1.10.10.660 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › conserved protein of unknown function from Enterococcus faecalis V583 | 0.54 | 37.0 | 3.51e-01 | 73.2% | 58.6% |
| 1gjsA00 | 1.10.8.40 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Albumin-binding domain | 0.54 | 37.0 | 3.63e-01 | 78.6% | 66.2% |
| 2m4eA00 | 1.20.120.1930 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Uncharacterised protein PF16691 family | 0.51 | 44.0 | 3.86e-01 | 100.0% | 91.9% |
ECOD (22)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1681684 | 244.1.1.9 ↗ | a+b two layers › FAD-linked reductases, C-terminal domain-like › FAD-linked reductases-C › FAD-linked reductases-C › GMC_oxred_C | 0.80 | 60.0 | 3.96e-01 | 78.6% | 22.7% |
| 3970007 | 3502.1.1.0 ↗ | alpha bundles › uncharacterized conserved protein › uncharacterized conserved protein › uncharacterized conserved protein | 0.67 | 53.0 | 4.88e-01 | 91.1% | 66.7% |
| None | — | 0.67 | 50.0 | 2.98e-01 | 80.4% | 15.1% | |
| 3287886 | 191.1.1.18 ↗ | alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › TetR_C_14 | 0.66 | 56.0 | 4.31e-01 | 100.0% | 83.3% |
| 2075033 | 3787.1.1.0 ↗ | alpha bundles › HAD superfamily helical bundle insertion domain | 0.65 | 51.0 | 4.69e-01 | 96.4% | 64.6% |
| 4341780 | 4957.1.1.0 ↗ | a+b complex topology › helical domain in yeast RNA-polymerases › third helical domain in yeast RNA-polymerase II beta-prime subunit › third helical domain in yeast RNA-polymerase II beta-prime subunit | 0.64 | 44.0 | 4.29e-01 | 73.2% | 66.2% |
| 3611276 | 4953.1.1.0 ↗ | beta barrels › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like | 0.64 | 46.0 | 3.93e-01 | 80.4% | 45.0% |
| 4929712 | 140.1.1.11 ↗ | alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › DALR_1 | 0.64 | 46.0 | 3.18e-01 | 80.4% | 25.0% |
| 3641558 | 109.4.1.1188 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › ORMDL | 0.63 | 46.0 | 3.58e-01 | 82.1% | 37.8% |
| 3533067 | 101.1.2.352 ↗ | alpha arrays › HTH › HTH › winged helix domain › HTH_Tnp_Tc5 | 0.61 | 42.0 | 3.96e-01 | 73.2% | 60.0% |
| 5045968 | 2004.1.1.42 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › T2SSE | 0.61 | 48.0 | 2.84e-01 | 94.6% | 10.4% |
| 3547329 | 101.1.1.21 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › HTH_Tnp_Tc5 | 0.61 | 41.0 | 3.69e-01 | 73.2% | 48.2% |
| 152872 | 191.1.1.4 ↗ | alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › TetR_C_2 | 0.59 | 47.0 | 3.76e-01 | 94.6% | 92.2% |
| 5069732 | 545.1.2.0 ↗ | alpha bundles › Gametocyte protein Pfg27-related › Gametocyte protein Pfg27-related › Sporozoite protein UIS3 soluble domain | 0.59 | 45.0 | 3.99e-01 | 91.1% | 57.5% |
| 3398327 | 103.12.1.6 ↗ | alpha arrays › RuvA-C › ANTAR domain › ANTAR domain › Tea_helical | 0.59 | 45.0 | 4.64e-01 | 98.2% | 96.0% |
| 3884722 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.57 | 43.0 | 4.19e-01 | 85.7% | 84.6% |
| 3652698 | 213.1.1.72 ↗ | a+b three layers › Nat/Ivy › Acyl-CoA N-acyltransferases (Nat) › Acyl-CoA N-acyltransferases (Nat) › Acetyltransf_1, Acetyltransf_10 | 0.56 | 40.0 | 2.84e-01 | 78.6% | 21.6% |
| 4634818 | 101.1.2.309 ↗ | alpha arrays › HTH › HTH › winged helix domain › GPAT_C | 0.56 | 39.0 | 3.81e-01 | 76.8% | 66.2% |
| 4975636 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.55 | 47.0 | 2.93e-01 | 96.4% | 98.7% |
| 3667637 | 4126.1.1.1 ↗ | a/b three-layered sandwiches › beta-carbonic anhydrase-like › beta-carbonic anhydrase › beta-carbonic anhydrase › Pro_CA | 0.54 | 45.0 | 3.18e-01 | 98.2% | 61.5% |
| 4980598 | 140.1.1.0 ↗ | alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0.54 | 42.0 | 3.00e-01 | 96.4% | 74.5% |
| 3261428 | 622.4.1.0 ↗ | alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related | 0.52 | 36.0 | 2.94e-01 | 78.6% | 46.2% |