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putative_RNA-dependent_RNA_polymerase

Euk-Vir

Melon_partitivirus

putative_RNA-dependent_RNA_polymerase__YP_009551627__Melon_partitivirus__2305257

Identity

Accession:
YP_009551627 ↗
Protein ID:
putative_RNA-dependent_RNA_polymerase
Kingdom:
euk

Quality

90.6 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 34-62_408-477
PDB
D2 medium residues 63-113_179-192_208-223_261-320
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00680.26 best RdRP_1 32.5 5.80e-08 44.7% 12.9%
CATH (2)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1w53A00 1.10.1240.30 Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › KaiA/RbsU domain 0.55 33.0 4.13e-01 75.2% 100.0%
5ctrA01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.52 32.0 2.52e-01 73.8% 28.5%
ECOD (5)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
2541763 304.48.1.8 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RdRP_1 0.82 77.0 5.52e-01 100.0% 69.9%
217141 304.48.1.15 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RdRP_3 0.79 73.0 5.35e-01 100.0% 68.3%
4859811 304.48.1.7 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Flu_PB1 0.74 68.0 4.72e-01 100.0% 76.7%
5016111 192.11.1.0 alpha bundles › Long alpha-hairpin › C-terminal UvrC-binding domain of UvrB › C-terminal UvrC-binding domain of UvrB 0.56 19.0 2.85e-01 70.9% 69.1%
3615476 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.55 49.0 3.69e-01 95.7% 75.4%
D3 medium residues 114-178_193-207
PDB
Domain cluster: representative
CATH (4)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2pggA01 3.90.1730.10 Alpha Beta › Alpha-Beta Complex › Infectious bursal virus vp1 polymerase fold › Infectious bursal virus vp1 polymerase domain 0.78 72.0 4.65e-01 100.0% 35.3%
3hbxA01 4.10.280.50 Few Secondary Structures › Irregular › MYOD Basic-Helix-Loop-Helix Domain, subunit B › 0.55 27.0 3.18e-01 77.5% 64.8%
3owaA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.50 40.0 3.17e-01 87.5% 70.8%
2yzcA00 3.10.270.10 Alpha Beta › Roll › Urate Oxidase › Urate Oxidase; 0.50 40.0 2.78e-01 88.7% 58.2%
ECOD (6)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
1145898 304.48.2.1 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › 'palm' domain in birnaviruse RNA-dependent RNA polymerase › Birna_RdRp_palm 0.81 76.0 4.50e-01 100.0% 22.0%
None 0.81 75.0 4.49e-01 100.0% 22.6%
4407977 109.4.1.1355 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › COG6_N, COG6_C 0.58 42.0 2.53e-01 77.5% 12.9%
3938404 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.57 42.0 3.28e-01 80.0% 65.9%
3793297 180.1.1.1 alpha bundles › Acid phosphatase/Vanadium-dependent haloperoxidase › Acid phosphatase/Vanadium-dependent haloperoxidase › Acid phosphatase/Vanadium-dependent haloperoxidase › PAP2 0.57 38.0 2.71e-01 70.0% 26.5%
3192094 5001.1.1.87 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › EXS 0.51 45.0 2.91e-01 100.0% 23.9%
D4 medium residues 224-260_321-407
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00680.26 best RdRP_1 62.7 3.90e-17 70.2% 21.1%