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putative_RNaseH
Euk-VirCafeteria_roenbergensis_virus_BV-PW1
putative_RNaseH__YP_003969643__Cafeteria_roenbergensis_virus_BV-PW1__693272
Identity
- Accession:
- YP_003969643 ↗
- Protein ID:
- putative_RNaseH
- Kingdom:
- euk
Quality
86.0
mean pLDDT
Taxonomy
Bamfordvirae›
Nucleocytoviricota›
Megaviricetes›
Imitervirales›
Mimiviridae›
Rheavirus›
Cafeteria_roenbergensis_virus_BV-PW1
TaxID: 693272
Cluster
View cluster (44 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 2-197
Domain cluster:
rep: NC_070967.1__YP_010671382.1__PQC17_gp233__00233__D3-158_252-294
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF02739.23 best | 5_3_exonuc_N | 47.6 | 2.10e-12 | 100.0% | 92.1% |
CATH (13)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1xo1A02 | 3.40.50.1010 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 5'-nuclease | 0.86 | 57.0 | 6.35e-01 | 100.0% | 82.4% |
| 3zdbA01 | 3.40.50.1010 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 5'-nuclease | 0.84 | 65.0 | 7.28e-01 | 100.0% | 98.7% |
| 4ymiB00 | 3.40.50.620 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs | 0.63 | 47.0 | 4.71e-01 | 99.5% | 75.8% |
| 2ah5A01 | 3.40.50.1000 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like | 0.60 | 39.0 | 4.46e-01 | 99.5% | 88.9% |
| 3a1fA00 | 3.40.50.80 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module | 0.59 | 43.0 | 4.69e-01 | 96.4% | 89.6% |
| 7x0hC01 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.57 | 36.0 | 4.22e-01 | 77.6% | 90.5% |
| 1nmnA00 | 3.30.420.140 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › YqgF/RNase H-like domain | 0.54 | 33.0 | 4.06e-01 | 79.6% | 98.3% |
| 3milB00 | 3.40.50.1110 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › SGNH hydrolase | 0.53 | 39.0 | 3.63e-01 | 82.7% | 61.8% |
| 4ktwA00 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.52 | 38.0 | 4.17e-01 | 99.0% | 93.1% |
| 2zosB01 | 3.40.50.1000 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like | 0.51 | 40.0 | 4.37e-01 | 98.5% | 99.4% |
| 1jx7A00 | 3.40.1260.10 | Alpha Beta › 3-Layer(aba) Sandwich › Hypothetical Protein Ychn; Chain: A, › DsrEFH-like | 0.51 | 31.0 | 3.85e-01 | 86.7% | 100.0% |
| 4dqlA03 | 3.40.50.80 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module | 0.51 | 38.0 | 4.14e-01 | 96.4% | 93.8% |
| 4wi1A02 | 3.40.50.800 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Anticodon-binding domain | 0.50 | 28.0 | 3.51e-01 | 98.0% | 87.8% |
ECOD (27)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3942445 | 2006.1.4.4 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › 5_3_exonuc_N | 0.88 | 66.0 | 6.81e-01 | 100.0% | 80.5% |
| 4355422 | 2006.1.4.4 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › 5_3_exonuc_N | 0.88 | 67.0 | 7.07e-01 | 100.0% | 86.3% |
| 3964138 | 2006.1.4.4 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › 5_3_exonuc_N | 0.88 | 69.0 | 7.23e-01 | 100.0% | 87.2% |
| 3261281 | 2006.1.4.4 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › 5_3_exonuc_N | 0.88 | 69.0 | 7.46e-01 | 100.0% | 93.5% |
| 4136793 | 2006.1.4.4 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › 5_3_exonuc_N | 0.88 | 74.0 | 7.23e-01 | 100.0% | 81.0% |
| 4299585 | 2006.1.4.4 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › 5_3_exonuc_N | 0.88 | 69.0 | 7.10e-01 | 100.0% | 84.9% |
| 4324598 | 2006.1.4.4 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › 5_3_exonuc_N | 0.88 | 67.0 | 6.97e-01 | 100.0% | 83.2% |
| 3969358 | 2006.1.4.0 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like | 0.87 | 68.0 | 7.47e-01 | 99.5% | 96.9% |
| 4995752 | 2006.1.4.4 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › 5_3_exonuc_N | 0.86 | 68.0 | 7.36e-01 | 100.0% | 95.8% |
| 4238071 | 2006.1.4.4 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › 5_3_exonuc_N | 0.86 | 71.0 | 7.48e-01 | 100.0% | 94.9% |
| 4031817 | 2006.1.4.4 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › 5_3_exonuc_N | 0.85 | 68.0 | 7.31e-01 | 100.0% | 94.1% |
| 4157264 | 2006.1.4.4 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › 5_3_exonuc_N | 0.85 | 70.0 | 7.33e-01 | 100.0% | 92.8% |
| 4125023 | 2006.1.4.4 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › 5_3_exonuc_N | 0.84 | 67.0 | 7.22e-01 | 100.0% | 94.1% |
| 3942272 | 2006.1.4.4 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › 5_3_exonuc_N | 0.84 | 68.0 | 7.32e-01 | 100.0% | 95.9% |
| 4031881 | 2006.1.4.4 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › 5_3_exonuc_N | 0.83 | 69.0 | 7.28e-01 | 100.0% | 94.9% |
| 4029535 | 2006.1.4.4 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › 5_3_exonuc_N | 0.83 | 70.0 | 7.29e-01 | 100.0% | 94.4% |
| 3329169 | 2006.1.4.4 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › 5_3_exonuc_N | 0.78 | 62.0 | 6.55e-01 | 100.0% | 91.4% |
| 3716209 | 2006.1.4.5 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › XRN_N | 0.72 | 68.0 | 5.42e-01 | 99.0% | 66.9% |
| 3251911 | 2006.1.4.5 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › XRN_N | 0.70 | 65.0 | 6.28e-01 | 100.0% | 86.8% |
| 3274669 | 2006.1.4.6 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › Fcf1 | 0.69 | 46.0 | 5.01e-01 | 100.0% | 81.2% |
| 4237276 | 2006.1.4.1 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › XPG_N,XPG_I | 0.67 | 58.0 | 5.71e-01 | 100.0% | 86.2% |
| 5030178 | 2006.1.4.3 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › NYN | 0.65 | 50.0 | 5.34e-01 | 99.5% | 89.7% |
| 3949665 | 2006.1.4.0 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like | 0.65 | 49.0 | 5.28e-01 | 99.0% | 90.6% |
| 3267040 | 2005.1.1.3 ↗ | a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › Usp | 0.60 | 43.0 | 4.96e-01 | 95.9% | 100.0% |
| 4999143 | 2005.1.1.3 ↗ | a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › Usp | 0.55 | 44.0 | 4.77e-01 | 96.9% | 98.8% |
| 3594808 | 2006.1.1.0 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like | 0.52 | 46.0 | 4.42e-01 | 97.4% | 86.0% |
| 4029267 | 7579.1.1.42 ↗ | a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Hydrolase_4 | 0.50 | 43.0 | 3.32e-01 | 92.3% | 83.1% |
D2
high
residues 198-265
Domain cluster:
representative
CATH (13)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5hmlA02 | 1.10.150.20 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 5' to 3' exonuclease, C-terminal subdomain | 0.73 | 66.0 | 6.22e-01 | 98.5% | 92.5% |
| 1b43A02 | 1.10.150.20 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 5' to 3' exonuclease, C-terminal subdomain | 0.70 | 53.0 | 5.54e-01 | 98.5% | 91.8% |
| 6h7bA01 | 1.10.1900.10 | Mainly Alpha › Orthogonal Bundle › c-terminal domain of poly(a) binding protein › c-terminal domain of poly(a) binding protein | 0.69 | 49.0 | 4.80e-01 | 83.8% | 68.9% |
| 2a7oA00 | 1.10.1740.100 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › Set2, Rpb1 interacting domain | 0.63 | 49.0 | 4.27e-01 | 82.4% | 80.0% |
| 4yozA01 | 1.10.472.10 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like | 0.63 | 54.0 | 4.03e-01 | 98.5% | 57.2% |
| 2oerA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.60 | 45.0 | 3.35e-01 | 80.9% | 40.8% |
| 3mvpA02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.55 | 42.0 | 3.27e-01 | 83.8% | 48.3% |
| 1lvlA01 | 3.50.50.60 | Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain | 0.54 | 39.0 | 2.80e-01 | 77.9% | 97.7% |
| 2acxA01 | 1.10.167.10 | Mainly Alpha › Orthogonal Bundle › Regulator of G-protein Signalling 4; domain 2 › Regulator of G-protein Signalling 4, domain 2 | 0.52 | 38.0 | 2.86e-01 | 86.8% | 27.8% |
| 7kz9A02 | 3.10.105.10 | Alpha Beta › Roll › Dipeptide-binding Protein; domain 3 › Dipeptide-binding Protein; Domain 3 | 0.52 | 42.0 | 3.10e-01 | 97.1% | 31.2% |
| 6nd0A01 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.51 | 42.0 | 3.80e-01 | 97.1% | 66.3% |
| 4huqA00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.51 | 43.0 | 2.86e-01 | 95.6% | 26.8% |
| 5zxdA01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.50 | 43.0 | 3.25e-01 | 100.0% | 55.4% |
ECOD (11)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3329195 | 102.1.1.4 ↗ | alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like › 5_3_exonuc | 0.79 | 71.0 | 5.73e-01 | 98.5% | 64.0% |
| 3641047 | 102.1.1.4 ↗ | alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like › 5_3_exonuc | 0.78 | 68.0 | 6.42e-01 | 94.1% | 96.2% |
| 3956065 | 102.1.1.4 ↗ | alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like › 5_3_exonuc | 0.77 | 68.0 | 6.43e-01 | 97.1% | 95.0% |
| 2168201 | 102.1.1.4 ↗ | alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like › 5_3_exonuc | 0.76 | 66.0 | 5.36e-01 | 95.6% | 59.5% |
| 4030601 | 102.1.1.4 ↗ | alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like › 5_3_exonuc | 0.76 | 69.0 | 5.69e-01 | 98.5% | 63.5% |
| 2074406 | 102.1.1.4 ↗ | alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like › 5_3_exonuc | 0.74 | 67.0 | 5.68e-01 | 98.5% | 69.8% |
| 4995753 | 102.1.1.4 ↗ | alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like › 5_3_exonuc | 0.72 | 63.0 | 5.27e-01 | 98.5% | 61.3% |
| 4030950 | 102.1.1.4 ↗ | alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like › 5_3_exonuc | 0.71 | 61.0 | 5.16e-01 | 97.1% | 61.7% |
| 3927014 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.57 | 46.0 | 3.75e-01 | 97.1% | 75.3% |
| 3230930 | 103.4.1.5 ↗ | alpha arrays › RuvA-C › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › KIX_2 | 0.56 | 44.0 | 4.18e-01 | 88.2% | 78.8% |
| 4935538 | 7583.1.1.1 ↗ | a/b three-layered sandwiches › Rossmann-like domain in AF1104-like proteins › Rossmann-like domain in AF1104-like proteins › Rossmann-like domain in AF1104-like proteins › ARMT1-like_dom | 0.54 | 40.0 | 2.82e-01 | 79.4% | 27.3% |