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putative_eIF-4E
Euk-VirCafeteria_roenbergensis_virus_BV-PW1
putative_eIF-4E__YP_003969852__Cafeteria_roenbergensis_virus_BV-PW1__693272
Identity
- Accession:
- YP_003969852 ↗
- Protein ID:
- putative_eIF-4E
- Kingdom:
- euk
Quality
70.5
mean pLDDT
Taxonomy
Bamfordvirae›
Nucleocytoviricota›
Megaviricetes›
Imitervirales›
Mimiviridae›
Rheavirus›
Cafeteria_roenbergensis_virus_BV-PW1
TaxID: 693272
Cluster
View cluster (13 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 1-66
Domain cluster:
representative
CATH (33)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5abxA00 | 3.30.760.10 | Alpha Beta › 2-Layer Sandwich › RNA Cap, Translation Initiation Factor Eif4e › RNA Cap, Translation Initiation Factor Eif4e | 0.80 | 70.0 | 5.00e-01 | 93.9% | 37.0% |
| 3hxiA01 | 3.30.760.10 | Alpha Beta › 2-Layer Sandwich › RNA Cap, Translation Initiation Factor Eif4e › RNA Cap, Translation Initiation Factor Eif4e | 0.80 | 68.0 | 4.94e-01 | 92.4% | 36.8% |
| 2wmcA00 | 3.30.760.10 | Alpha Beta › 2-Layer Sandwich › RNA Cap, Translation Initiation Factor Eif4e › RNA Cap, Translation Initiation Factor Eif4e | 0.80 | 69.0 | 4.92e-01 | 92.4% | 37.9% |
| 4b6uA00 | 3.30.760.10 | Alpha Beta › 2-Layer Sandwich › RNA Cap, Translation Initiation Factor Eif4e › RNA Cap, Translation Initiation Factor Eif4e | 0.79 | 68.0 | 4.69e-01 | 93.9% | 32.9% |
| 1ap8A00 | 3.30.760.10 | Alpha Beta › 2-Layer Sandwich › RNA Cap, Translation Initiation Factor Eif4e › RNA Cap, Translation Initiation Factor Eif4e | 0.65 | 54.0 | 3.89e-01 | 97.0% | 32.4% |
| 7dryA01 | 3.40.140.10 | Alpha Beta › 3-Layer(aba) Sandwich › Cytidine Deaminase; domain 2 › Cytidine Deaminase, domain 2 | 0.63 | 51.0 | 3.77e-01 | 90.9% | 74.5% |
| 3lqcA00 | 2.60.120.260 | Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding domain-like | 0.58 | 47.0 | 3.63e-01 | 89.4% | 48.3% |
| 2gx8A02 | 3.30.70.120 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.58 | 45.0 | 4.04e-01 | 87.9% | 93.9% |
| 6gdxA00 | 3.30.70.120 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.58 | 44.0 | 3.88e-01 | 86.4% | 83.2% |
| 1o7fA01 | 2.60.120.10 | Mainly Beta › Sandwich › Jelly Rolls › Jelly Rolls | 0.57 | 48.0 | 3.75e-01 | 98.5% | 63.2% |
| 4gucA00 | 2.60.40.3720 | Mainly Beta › Sandwich › Immunoglobulin-like › | 0.56 | 47.0 | 3.97e-01 | 93.9% | 60.9% |
| 2yweA04 | 3.30.70.240 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.56 | 44.0 | 3.83e-01 | 92.4% | 96.5% |
| 1x4xA00 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.56 | 41.0 | 3.53e-01 | 86.4% | 49.1% |
| 5vqfD01 | 2.60.120.970 | Mainly Beta › Sandwich › Jelly Rolls › | 0.56 | 48.0 | 3.31e-01 | 95.5% | 61.5% |
| 2x41A03 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.56 | 46.0 | 3.77e-01 | 89.4% | 62.2% |
| 2g7zA02 | 3.30.1180.10 | Alpha Beta › 2-Layer Sandwich › Hypothetical Protein Tm841; Chain: A;domain 3 › | 0.56 | 42.0 | 3.52e-01 | 83.3% | 85.0% |
| 5z9sA03 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.54 | 44.0 | 3.60e-01 | 89.4% | 60.2% |
| 3zyzA03 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.54 | 44.0 | 3.57e-01 | 90.9% | 60.6% |
| 4i3gA04 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.54 | 43.0 | 3.63e-01 | 87.9% | 65.8% |
| 4gr5C01 | 3.90.820.10 | Alpha Beta › Alpha-Beta Complex › Rubredoxin-like › Structural Genomics, Unknown Function 30-nov-00 1gh9 Mol_id | 0.53 | 37.0 | 3.80e-01 | 74.2% | 84.4% |
| 5jp0A03 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.53 | 41.0 | 3.32e-01 | 83.3% | 56.5% |
| 2ia0B02 | 3.30.70.920 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Lrp/AsnC effector binding domain/regulation of amino acid metabolism (RAM) domain | 0.53 | 41.0 | 3.67e-01 | 87.9% | 77.8% |
| 5e1qA03 | 2.60.40.1180 | Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II | 0.53 | 39.0 | 3.52e-01 | 93.9% | 56.2% |
| 4u7cB04 | 3.30.1490.100 | Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › DNA polymerase, Y-family, little finger domain | 0.52 | 39.0 | 3.43e-01 | 84.8% | 58.7% |
| 2kd7A00 | 2.60.120.260 | Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding domain-like | 0.52 | 39.0 | 3.09e-01 | 98.5% | 35.2% |
| 2vvfA01 | 2.60.120.730 | Mainly Beta › Sandwich › Jelly Rolls › | 0.52 | 42.0 | 3.39e-01 | 93.9% | 58.9% |
| 1qg3A02 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.52 | 41.0 | 3.56e-01 | 87.9% | 57.7% |
| 3fdwA00 | 2.60.40.150 | Mainly Beta › Sandwich › Immunoglobulin-like › C2 domain | 0.52 | 41.0 | 3.35e-01 | 87.9% | 53.1% |
| 1pfoA01 | 3.90.840.10 | Alpha Beta › Alpha-Beta Complex › HIV-1 Reverse Transcriptase; Chain A, domain 3 › Thiol-activated cytolysin superfamily/Thiol-activated cytolysin, alpha-beta domain | 0.52 | 38.0 | 2.90e-01 | 83.3% | 73.8% |
| 1jhjA00 | 2.60.120.260 | Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding domain-like | 0.51 | 42.0 | 3.24e-01 | 93.9% | 86.3% |
| 1vwxS01 | 3.10.20.10 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › | 0.51 | 40.0 | 4.01e-01 | 93.9% | 93.0% |
| 2qg3A00 | 3.30.1960.10 | Alpha Beta › 2-Layer Sandwich › SSo0622-like fold › tRNA wybutosine-synthesizing-like | 0.51 | 40.0 | 2.94e-01 | 89.4% | 59.3% |
| 4a18X01 | 3.10.20.10 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › | 0.50 | 40.0 | 3.89e-01 | 97.0% | 94.9% |
ECOD (38)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3699127 | 317.1.1.1 ↗ | a+b two layers › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › IF4E | 0.80 | 69.0 | 4.82e-01 | 92.4% | 34.6% |
| 3932136 | 317.1.1.1 ↗ | a+b two layers › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › IF4E | 0.79 | 67.0 | 4.69e-01 | 92.4% | 31.5% |
| 3478629 | 317.1.1.1 ↗ | a+b two layers › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › IF4E | 0.78 | 68.0 | 4.72e-01 | 93.9% | 31.5% |
| 3237087 | 317.1.1.1 ↗ | a+b two layers › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › IF4E | 0.78 | 68.0 | 4.72e-01 | 93.9% | 32.0% |
| 4020284 | 317.1.1.1 ↗ | a+b two layers › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › IF4E | 0.78 | 69.0 | 4.69e-01 | 95.5% | 34.9% |
| 3457076 | 317.1.1.1 ↗ | a+b two layers › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › IF4E | 0.78 | 67.0 | 4.68e-01 | 92.4% | 34.0% |
| 3516243 | 317.1.1.1 ↗ | a+b two layers › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › IF4E | 0.77 | 66.0 | 4.54e-01 | 93.9% | 29.7% |
| 162529 | 317.1.1.1 ↗ | a+b two layers › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › IF4E | 0.77 | 65.0 | 4.51e-01 | 93.9% | 29.5% |
| 3709979 | 317.1.1.0 ↗ | a+b two layers › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase | 0.67 | 56.0 | 3.78e-01 | 92.4% | 25.7% |
| 3538311 | 11.1.1.469 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › fn3_4 | 0.61 | 48.0 | 3.99e-01 | 86.4% | 52.5% |
| 3290666 | 10.32.1.0 ↗ | beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like | 0.60 | 44.0 | 3.45e-01 | 86.4% | 35.9% |
| 3354676 | 10.9.1.1 ↗ | beta sandwiches › jelly-roll › C-terminal domain of mullusc hemocyanin › C-terminal domain of mullusc hemocyanin › PPO1_KFDV | 0.60 | 48.0 | 4.42e-01 | 86.4% | 83.5% |
| 3412857 | 11.1.1.469 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › fn3_4 | 0.60 | 47.0 | 3.99e-01 | 86.4% | 57.3% |
| 3894642 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.60 | 48.0 | 4.10e-01 | 87.9% | 71.4% |
| 5036166 | 12.1.1.0 ↗ | beta sandwiches › Glycosyl hydrolase domain-like › Glycosyl hydrolase domain › Glycosyl hydrolase domain | 0.58 | 45.0 | 4.14e-01 | 87.9% | 65.9% |
| 3998176 | 10.32.1.0 ↗ | beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like | 0.57 | 46.0 | 3.60e-01 | 89.4% | 42.8% |
| 3539315 | 10.12.1.1 ↗ | beta sandwiches › jelly-roll › Double-stranded beta-helix › Double-stranded beta-helix › cNMP_binding | 0.56 | 48.0 | 3.65e-01 | 98.5% | 57.6% |
| 1823919 | 11.1.1.182 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Fn3-like | 0.56 | 46.0 | 3.76e-01 | 89.4% | 62.2% |
| 3601653 | 10.12.1.0 ↗ | beta sandwiches › jelly-roll › Double-stranded beta-helix › Double-stranded beta-helix | 0.56 | 47.0 | 3.71e-01 | 98.5% | 68.0% |
| 3230280 | 11.1.1.239 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › MG3 | 0.56 | 45.0 | 3.85e-01 | 87.9% | 62.9% |
| 4025348 | 10.32.1.0 ↗ | beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like | 0.55 | 42.0 | 3.34e-01 | 87.9% | 45.8% |
| 3784036 | 11.1.1.182 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Fn3-like | 0.55 | 44.0 | 3.18e-01 | 89.4% | 37.5% |
| 5065313 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.55 | 43.0 | 3.70e-01 | 87.9% | 60.0% |
| 4243510 | 10.2.1.5 ↗ | beta sandwiches › jelly-roll › Nucleoplasmin-like/VP (viral coat and capsid proteins) › Nucleoplasmin-like/VP (viral coat and capsid proteins) › TGFb_propeptide | 0.54 | 47.0 | 3.24e-01 | 97.0% | 30.8% |
| 4550201 | 10.2.1.0 ↗ | beta sandwiches › jelly-roll › Nucleoplasmin-like/VP (viral coat and capsid proteins) › Nucleoplasmin-like/VP (viral coat and capsid proteins) | 0.54 | 47.0 | 2.93e-01 | 97.0% | 19.2% |
| 3825952 | 221.1.1.4 ↗ | a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like › PB1 | 0.54 | 46.0 | 4.00e-01 | 97.0% | 68.6% |
| 2443819 | 11.1.1.182 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Fn3-like | 0.54 | 44.0 | 3.66e-01 | 89.4% | 63.2% |
| 3828980 | 10.32.1.241 ↗ | beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like › SAC9_GBDL_2nd | 0.54 | 46.0 | 3.27e-01 | 97.0% | 36.1% |
| 5056077 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.53 | 42.0 | 3.65e-01 | 87.9% | 59.0% |
| 3638666 | 10.32.1.28 ↗ | beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like › Sad1_UNC | 0.53 | 45.0 | 3.41e-01 | 95.5% | 38.8% |
| 3797406 | 10.1.1.0 ↗ | beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases | 0.53 | 45.0 | 3.27e-01 | 98.5% | 50.0% |
| 3232486 | 11.2.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain | 0.53 | 43.0 | 3.78e-01 | 93.9% | 62.9% |
| 5011417 | 304.4.1.20 ↗ | a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › AsnC_trans_reg2 | 0.52 | 41.0 | 3.77e-01 | 89.4% | 86.7% |
| 3215805 | 11.1.1.822 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › DUF229 | 0.52 | 44.0 | 3.84e-01 | 93.9% | 64.0% |
| 3212513 | 10.1.1.0 ↗ | beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases | 0.52 | 44.0 | 3.33e-01 | 98.5% | 56.6% |
| 4030243 | 304.24.1.0 ↗ | a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like | 0.52 | 40.0 | 3.56e-01 | 89.4% | 77.1% |
| 5083482 | 12.1.1.22 ↗ | beta sandwiches › Glycosyl hydrolase domain-like › Glycosyl hydrolase domain › Glycosyl hydrolase domain › GH97_C | 0.51 | 37.0 | 3.42e-01 | 93.9% | 56.8% |
| 4951859 | 3110.1.1.3 ↗ | a/b three-layered sandwiches › STT3/PglB/AglB core domain › STT3/PglB/AglB core domain › STT3/PglB/AglB core domain › AglB_core-like | 0.50 | 40.0 | 2.78e-01 | 100.0% | 22.9% |
D2
medium
residues 67-163