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putative_helicase
Euk-VirLausannevirus
putative_helicase__YP_004346969__Lausannevirus__999883
Identity
- Accession:
- YP_004346969 ↗
- Protein ID:
- putative_helicase
- Kingdom:
- euk
Quality
76.7
mean pLDDT
Taxonomy
Bamfordvirae›
Nucleocytoviricota›
Megaviricetes›
Pimascovirales›
Marseilleviridae›
Losannavirus›
Lausannevirus
TaxID: 999883
Cluster
View cluster (17 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 186-348
D2
high
residues 369-456
D3
high
residues 473-637
Domain cluster:
rep: MK064563__AZI75768.1__SBFV2-gp01__00001__D223-383
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF02399.22 best | Herpes_ori_bp | 48.6 | 5.30e-13 | 96.4% | 20.4% |
D4
medium
residues 22-54_997-1097
D5
medium
residues 70-185_940-996
Domain cluster:
rep: putative_helicase__YP_009238527__Brazilian_marseillevirus__1813599__D17-175_881-925
CATH (8)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3dfeA00 | 3.30.70.120 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.55 | 25.0 | 3.51e-01 | 84.4% | 87.8% |
| 2if1A00 | 3.30.780.10 | Alpha Beta › 2-Layer Sandwich › Translation Initiation Factor Eif1 › SUI1-like domain | 0.53 | 27.0 | 3.15e-01 | 78.6% | 65.1% |
| 5zneA00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.53 | 22.0 | 3.20e-01 | 72.8% | 86.3% |
| 1x7vA00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.52 | 26.0 | 3.29e-01 | 74.6% | 80.6% |
| 2gffA00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.51 | 26.0 | 3.25e-01 | 74.0% | 81.2% |
| 2vd3A03 | 3.30.70.120 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.51 | 22.0 | 3.20e-01 | 85.0% | 91.9% |
| 2oikA00 | 3.30.428.10 | Alpha Beta › 2-Layer Sandwich › HIT family, subunit A › HIT-like | 0.50 | 36.0 | 3.93e-01 | 85.5% | 90.6% |
| 4hl9A00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.50 | 26.0 | 3.26e-01 | 74.6% | 85.1% |
ECOD (11)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5068310 | 305.1.1.0 ↗ | a+b two layers › DCoH-like › RBP11-like subunits of RNA polymerase › RBP11-like subunits of RNA polymerase | 0.56 | 26.0 | 3.64e-01 | 72.8% | 92.5% |
| 3807592 | 304.8.1.0 ↗ | a+b two layers › Alpha-beta plaits › ACT-like › ACT-like | 0.56 | 23.0 | 3.32e-01 | 72.8% | 85.7% |
| 4927243 | 304.4.1.30 ↗ | a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › DUF3291 | 0.55 | 27.0 | 3.14e-01 | 74.0% | 62.4% |
| 4365813 | 306.2.1.1 ↗ | a+b two layers › Glucose permease domain IIB-like › arginine repressor C terminal domain-related › C-terminal domain of arginine repressor › Arg_repressor_C | 0.53 | 26.0 | 3.47e-01 | 80.3% | 91.6% |
| 3752343 | 304.24.1.0 ↗ | a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like | 0.53 | 20.0 | 3.17e-01 | 74.0% | 98.2% |
| 3232593 | 304.9.1.0 ↗ | a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD | 0.53 | 24.0 | 3.29e-01 | 73.4% | 82.2% |
| 3439358 | 304.9.1.1 ↗ | a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 | 0.51 | 27.0 | 3.08e-01 | 71.7% | 67.2% |
| 3463392 | 304.3.1.0 ↗ | a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain | 0.51 | 21.0 | 3.14e-01 | 72.8% | 93.8% |
| 4887048 | 304.5.1.0 ↗ | a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like | 0.51 | 21.0 | 3.05e-01 | 86.1% | 85.1% |
| 3657793 | 304.3.1.0 ↗ | a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain | 0.51 | 21.0 | 3.07e-01 | 72.3% | 92.3% |
| 4254767 | 306.1.1.1 ↗ | a+b two layers › Glucose permease domain IIB-like › Glucose permease domain IIB › Glucose permease domain IIB › PTS_EIIB | 0.50 | 28.0 | 3.60e-01 | 97.1% | 100.0% |
D6
medium
residues 643-771
Domain cluster:
rep: DNA_replication_origin-binding_helicase__YP_009010995__Chimpanzee_herpesvirus_strain_105640__332937__D268-285_303-382_532-556
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF02399.22 best | Herpes_ori_bp | 35.0 | 6.60e-09 | 93.8% | 13.2% |
D7
medium
residues 772-855
Domain cluster:
representative
CATH (7)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4jfcA02 | 1.10.12.10 | Mainly Alpha › Orthogonal Bundle › Lyase 2-enoyl-coa Hydratase; Chain A, domain 2 › Lyase 2-enoyl-coa Hydratase, Chain A, domain 2 | 0.60 | 33.0 | 3.92e-01 | 83.3% | 80.4% |
| 3e9lA02 | 1.20.80.40 | Mainly Alpha › Up-down Bundle › Acyl-CoA Binding Protein › Prp8 RNase H domain, fingers region | 0.55 | 38.0 | 3.73e-01 | 72.6% | 70.5% |
| 3hhgE01 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.54 | 45.0 | 4.46e-01 | 92.9% | 94.3% |
| 1o7dC01 | 1.20.1270.50 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Glycoside hydrolase family 38, central domain | 0.53 | 36.0 | 4.10e-01 | 95.2% | 96.7% |
| 2iboA00 | 3.30.70.930 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.52 | 33.0 | 3.28e-01 | 72.6% | 60.7% |
| 2q5zB00 | 1.10.287.1080 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like | 0.51 | 38.0 | 3.70e-01 | 88.1% | 71.3% |
| 3l8rA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.50 | 35.0 | 3.34e-01 | 97.6% | 59.8% |
ECOD (11)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3226564 | 5054.1.1.58 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › YVC1_C | 0.60 | 50.0 | 3.39e-01 | 95.2% | 82.6% |
| 3484191 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.55 | 39.0 | 2.85e-01 | 75.0% | 43.5% |
| 3661482 | 4120.1.1.56 ↗ | few secondary structure elements › Tim10/DDP › Tim10/DDP › Tim10/DDP › Myb_DNA-bind_3 | 0.55 | 40.0 | 4.13e-01 | 91.7% | 83.7% |
| 3709339 | 2484.1.1.62 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › PRP8_domainIV | 0.55 | 39.0 | 2.82e-01 | 75.0% | 43.1% |
| 4177030 | 3826.1.1.81 ↗ | alpha bundles › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › CKI | 0.55 | 40.0 | 3.90e-01 | 95.2% | 69.5% |
| 3993742 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.54 | 46.0 | 4.01e-01 | 100.0% | 60.7% |
| 3236856 | 174.1.1.50 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › DUF7807 | 0.54 | 46.0 | 3.73e-01 | 100.0% | 48.0% |
| 5042767 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.52 | 37.0 | 3.60e-01 | 76.2% | 92.9% |
| 3865098 | 4351.1.1.1 ↗ | alpha arrays › ATP12-like › ATP12-like › ATP12-like › ATP12 | 0.52 | 39.0 | 2.83e-01 | 79.8% | 34.3% |
| 4972154 | 604.12.1.135 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › Oxidored_q2 | 0.51 | 36.0 | 3.48e-01 | 100.0% | 64.0% |
| 3557551 | 212.1.1.24 ↗ | a+b two layers › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Ribosomal protein S5 domain 2-like › Morc6_S5 | 0.50 | 44.0 | 3.79e-01 | 95.2% | 83.8% |
D8
medium
residues 856-939
Domain cluster:
rep: conserved_putative_helicase__YP_009094625__Melbournevirus__1560514__D838-914
CATH (9)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3nbiA01 | 1.10.8.1020 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › RecQ-mediated genome instability protein 1, N-terminal domain | 0.62 | 31.0 | 3.68e-01 | 81.0% | 69.0% |
| 6tmfI00 | 1.10.455.10 | Mainly Alpha › Orthogonal Bundle › Ribosomal Protein S7 › Ribosomal protein S7/S5 | 0.56 | 43.0 | 3.25e-01 | 84.5% | 66.4% |
| 3hr0B01 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.55 | 39.0 | 4.06e-01 | 90.5% | 78.5% |
| 7b7tA01 | 1.20.1270.30 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.54 | 48.0 | 3.86e-01 | 98.8% | 58.4% |
| 1t9kA01 | 1.20.120.420 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › translation initiation factor eif-2b, domain 1 | 0.54 | 40.0 | 3.38e-01 | 78.6% | 56.4% |
| 1jr8A00 | 1.20.120.310 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › ERV/ALR sulfhydryl oxidase domain | 0.53 | 41.0 | 3.84e-01 | 82.1% | 96.2% |
| 3tu3B03 | 1.20.1050.100 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.52 | 45.0 | 3.60e-01 | 96.4% | 59.4% |
| 1lxlA00 | 1.10.437.10 | Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like | 0.51 | 44.0 | 3.33e-01 | 98.8% | 41.6% |
| 4maaA01 | 3.40.50.2300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator | 0.50 | 38.0 | 3.00e-01 | 84.5% | 77.8% |
ECOD (4)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3237844 | 611.3.1.4 ↗ | alpha bundles › N-cbl like › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 › Pes-10 | 0.56 | 33.0 | 3.10e-01 | 70.2% | 47.6% |
| 3583180 | 1016.1.1.2 ↗ | alpha arrays › Dimerization domain in caprin-1 and PAN3 › Dimerization domain in caprin-1 and PAN3 › Dimerization domain in caprin-1 and PAN3 › Caprin-1_dimer | 0.54 | 49.0 | 4.28e-01 | 100.0% | 83.2% |
| 3712638 | 3187.1.1.0 ↗ | alpha bundles › Microtubule-Binding Domain of Flagellar Dynein › Microtubule-Binding Domain of Flagellar Dynein › Microtubule-Binding Domain of Flagellar Dynein | 0.51 | 42.0 | 3.54e-01 | 91.7% | 58.0% |
| 3744818 | 101.1.1.213 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › HRI2_3H | 0.50 | 34.0 | 3.55e-01 | 70.2% | 92.0% |