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putative_large_T_antigen

Euk-Vir

Crow_polyomavirus

putative_large_T_antigen__YP_529828__Crow_polyomavirus__349563

Identity

Accession:: YP_529828 ↗
Protein ID:: putative_large_T_antigen
Kingdom:: euk

Quality

82.4 mean pLDDT

Cluster

View cluster (129 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 1-61

PDB

Domain cluster: rep: small_T_antigen__YP_007346980__Betapolyomavirus_ptedavyi__1891773__D7-77

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF00226.37 best	DnaJ	42.7	6.80e-11	80.3%	73.0%

D2 high residues 145-241

PDB

Domain cluster: rep: large_T_antigen__YP_009115503__Adelie_penguin_polyomavirus__1590650__D167-268

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF02217.23 best	T_Ag_DNA_bind	116.1	1.30e-33	91.8%	93.6%

D3 high residues 266-362

PDB

Domain cluster: rep: ORF01L__YP_009252373__Marbled_eel_polyomavirus__1662286__D415-505

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF06431.17 best	Polyoma_lg_T_C	45.1	9.50e-12	100.0%	19.9%

D4 medium residues 368-405_561-631

PDB

Domain cluster: representative

CATH (23)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
1svmA02	1.20.1050.70	Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › Large T antigen, SV40, domain 3	0.80	74.0	7.26e-01	100.0%	96.6%
3u8vA00	1.20.120.660	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain	0.61	37.0	4.10e-01	89.9%	77.1%
3ousA00	1.10.287.70	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.58	39.0	4.45e-01	78.9%	91.5%
2v6yA00	1.20.58.80	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit	0.58	39.0	4.46e-01	92.7%	98.7%
8ctsB01	1.10.287.70	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.57	38.0	4.23e-01	78.0%	86.2%
1gxmB00	1.50.10.20	Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase ›	0.56	48.0	3.47e-01	100.0%	31.3%
3u3iA02	1.20.58.1110	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.56	44.0	4.46e-01	96.3%	86.1%
4jzaA02	1.10.520.60	Mainly Alpha › Orthogonal Bundle › Peroxidase; domain 1 ›	0.55	37.0	3.65e-01	70.6%	64.7%
6n6qD00	1.10.630.10	Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450	0.55	39.0	2.70e-01	76.1%	72.0%
4u7iA00	1.20.58.80	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit	0.54	42.0	4.48e-01	99.1%	98.9%
4rngC00	1.20.1280.290	Mainly Alpha › Up-down Bundle › Monooxygenase ›	0.53	37.0	4.07e-01	89.0%	92.8%
1w36C06	1.10.10.990	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A ›	0.53	33.0	3.88e-01	87.2%	94.4%
2lseA00	1.20.120.1360	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) ›	0.52	32.0	3.37e-01	89.9%	65.3%
7kypB01	1.10.3470.10	Mainly Alpha › Orthogonal Bundle › ABC transporter involved in vitamin B12 uptake, BtuC › ABC transporter involved in vitamin B12 uptake, BtuC	0.52	40.0	3.06e-01	83.5%	89.5%
1aepA00	1.20.120.20	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein	0.52	35.0	3.21e-01	70.6%	90.8%
1tqgA00	1.20.120.160	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain	0.51	33.0	3.38e-01	89.9%	66.7%
3mdmA00	1.10.630.10	Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450	0.51	42.0	2.84e-01	90.8%	75.9%
4h33A00	1.10.287.70	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.51	35.0	3.79e-01	78.0%	84.6%
7c1iA01	1.20.120.160	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain	0.51	29.0	3.05e-01	88.1%	61.0%
1xg2B00	1.20.140.40	Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein	0.51	37.0	3.43e-01	97.2%	57.0%
3l9vC00	3.40.30.10	Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin	0.51	39.0	3.38e-01	84.4%	93.4%
4gx0A01	1.10.287.70	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.50	35.0	3.62e-01	74.3%	74.8%
2z0qA01	1.20.900.10	Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain	0.50	43.0	3.65e-01	97.2%	91.2%

ECOD (17)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3628598	603.1.1.0 ↗	alpha bundles › STAT-like › t-snare proteins › t-snare proteins	0.58	41.0	4.63e-01	91.7%	100.0%
3742018	7094.1.1.2 ↗	alpha bundles › Paddle domain of mitochondrial dynamin › Paddle domain of mitochondrial dynamin › Paddle domain of mitochondrial dynamin › LIS_MGM1	0.57	39.0	4.08e-01	70.6%	78.9%
5024001	604.6.1.0 ↗	alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain	0.57	42.0	4.37e-01	97.2%	85.0%
3575050	5059.1.1.3 ↗	alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › TPT	0.56	41.0	3.37e-01	77.1%	59.5%
3762906	5050.1.1.9 ↗	alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1	0.55	40.0	3.09e-01	77.1%	50.9%
4134938	601.3.1.14 ↗	alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › PF27870	0.54	33.0	3.28e-01	88.1%	55.7%
3526937	101.1.10.1 ↗	alpha arrays › HTH › HTH › Cyclin-like › Cyclin_N	0.54	36.0	3.30e-01	80.7%	52.1%
3711163	192.15.1.0 ↗	alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains	0.53	41.0	3.54e-01	83.5%	85.0%
5006721	547.1.1.9 ↗	alpha duplicates or obligate multimers › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › DUF5658	0.53	37.0	3.60e-01	71.6%	72.5%
3829016	604.12.1.0 ↗	alpha bundles › Spectrin repeat-like › MIT domain › MIT domain	0.53	40.0	3.87e-01	94.5%	71.2%
3231223	5054.1.1.0 ↗	alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels	0.53	34.0	2.92e-01	77.1%	40.0%
3633174	604.1.1.55 ↗	alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › RasGAP_C	0.52	37.0	3.85e-01	88.1%	80.0%
3719613	1189.1.1.0 ↗	alpha bundles › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor	0.52	36.0	2.94e-01	71.6%	77.8%
3581266	604.6.1.0 ↗	alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain	0.52	42.0	4.24e-01	99.1%	89.1%
3367916	5067.1.1.13 ↗	alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › ALMT	0.51	37.0	3.31e-01	88.1%	52.9%
3782650	604.6.1.0 ↗	alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain	0.51	43.0	4.31e-01	96.3%	92.2%
4420734	5065.1.1.2 ↗	alpha bundles › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › FecCD	0.51	40.0	2.91e-01	85.3%	69.9%

D5 medium residues 406-560

PDB

Domain cluster: rep: MN062720.1__QDP45567.1__SEA_FUZZBUSTER_83__00083__D568-722_747-764

Pfam (2)

Accession	Name	Score	E-value	Q cov	HMM cov
PF06431.17 best	Polyoma_lg_T_C	173.6	9.60e-51	98.7%	34.5%
PF00519.24	PPV_E1_C	28.3	1.40e-06	87.1%	37.7%