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putative_mRNA_capping_enzyme

Euk-Vir

Cafeteria_roenbergensis_virus_BV-PW1

putative_mRNA_capping_enzyme__YP_003969844__Cafeteria_roenbergensis_virus_BV-PW1__693272

Identity

Accession:: YP_003969844 ↗
Protein ID:: putative_mRNA_capping_enzyme
Kingdom:: euk

Quality

66.8 mean pLDDT

Taxonomy

Bamfordvirae› Nucleocytoviricota› Megaviricetes› Imitervirales› Mimiviridae› Rheavirus› Cafeteria_roenbergensis_virus_BV-PW1

TaxID: 693272

Cluster

Singleton — not in a non-trivial cluster

3D Structure

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Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 36-217

PDB

D2 high residues 505-626

PDB

D3 medium residues 262-295_446-504_627-684

PDB

Domain cluster: representative

CATH (2)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3zq5A03	3.30.450.270	Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PHY domain	0.52	29.0	2.93e-01	90.1%	51.0%
4a18O00	3.30.390.110	Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 ›	0.52	29.0	3.08e-01	86.8%	61.9%

D4 medium residues 296-445

PDB

Domain cluster: rep: mRNA-capping_enzyme__YP_007354410__Acanthamoeba_polyphaga_moumouvirus__1269028__D239-430

CATH (14)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
1ckmA01	3.30.470.30	Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme	0.79	55.0	5.48e-01	92.7%	68.4%
4ckbA01	3.30.470.140	Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 ›	0.75	48.0	4.55e-01	100.0%	54.5%
3rtxA01	3.30.470.30	Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme	0.72	56.0	5.41e-01	92.7%	72.1%
1xk5A01	3.30.470.30	Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme	0.71	55.0	4.93e-01	100.0%	59.8%
3vnnA00	3.30.470.30	Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme	0.68	52.0	5.76e-01	95.3%	96.0%
4pz6A02	3.30.470.30	Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme	0.67	58.0	4.88e-01	97.3%	57.6%
2hivA02	3.30.470.30	Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme	0.65	56.0	4.93e-01	100.0%	65.0%
6rarI01	3.30.470.30	Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme	0.63	55.0	4.94e-01	100.0%	69.7%
6p0cA03	3.30.470.30	Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme	0.62	51.0	5.53e-01	91.3%	100.0%
3qwuA02	3.30.470.30	Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme	0.55	48.0	4.52e-01	97.3%	78.9%
2cxcA01	3.30.300.20	Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › K homology (KH) domain	0.54	26.0	3.69e-01	93.3%	100.0%
2w3pA02	3.90.226.10	Alpha Beta › Alpha-Beta Complex › 2-enoyl-CoA Hydratase; Chain A, domain 1 › 2-enoyl-CoA Hydratase; Chain A, domain 1	0.52	29.0	2.50e-01	90.0%	33.9%
1ylqA00	3.30.460.10	Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Beta Polymerase, domain 2	0.52	26.0	3.26e-01	89.3%	77.4%
5wceA03	3.10.150.10	Alpha Beta › Roll › DNA Polymerase III; Chain A, domain 2 › DNA Polymerase III, subunit A, domain 2	0.51	30.0	3.38e-01	92.7%	73.1%

ECOD (22)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
7118	206.1.3.4 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › mRNA_cap_enzyme	0.78	58.0	4.93e-01	98.0%	50.0%
3270724	206.1.3.4 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › mRNA_cap_enzyme	0.78	57.0	4.81e-01	98.0%	48.1%
3510295	206.1.3.30 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › SPN1_m3Gcap_bd	0.75	54.0	4.62e-01	100.0%	48.9%
4027847	206.1.3.4 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › mRNA_cap_enzyme	0.73	57.0	4.94e-01	97.3%	55.5%
423186	206.1.3.4 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › mRNA_cap_enzyme	0.72	59.0	4.99e-01	97.3%	54.3%
5066075	206.1.3.1 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M	0.65	55.0	4.96e-01	96.7%	67.2%
3281941	206.1.3.1 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M	0.65	55.0	4.96e-01	97.3%	67.2%
3500957	206.1.3.4 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › mRNA_cap_enzyme	0.64	60.0	4.92e-01	98.7%	70.0%
4914243	206.1.3.116 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M, DNA_ligase_A_C	0.63	53.0	4.72e-01	100.0%	64.9%
4213407	4095.1.1.2 ↗	alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M+DNA_ligase_A_N	0.60	54.0	3.93e-01	97.3%	38.0%
5026595	327.11.1.0 ↗	a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Prokaryotic type KH domain (KH-domain type II)	0.60	28.0	3.92e-01	86.7%	95.4%
4982571	56.2.1.1 ↗	beta sandwiches › Epsilon subunit of F1F0-ATP synthase-N › CO dehydrogenase accessory protein CooT › CO dehydrogenase accessory protein CooT › CooT	0.58	19.0	2.84e-01	92.7%	63.8%
3997608	206.1.3.0 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp	0.58	54.0	4.35e-01	100.0%	81.7%
5083927	206.1.3.1 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M	0.58	55.0	4.80e-01	100.0%	71.1%
3397951	4095.1.1.2 ↗	alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M+DNA_ligase_A_N	0.58	53.0	3.72e-01	100.0%	40.8%
3414267	206.1.3.0 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp	0.58	53.0	4.42e-01	100.0%	82.3%
4532808	2.1.1.60 ↗	beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › RsgI_N	0.57	21.0	3.44e-01	88.7%	96.0%
4668736	206.1.3.0 ↗	a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp	0.56	46.0	4.55e-01	96.7%	82.5%
3291440	227.1.1.0 ↗	a+b two layers › DNA clamp › DNA clamp › DNA clamp	0.56	31.0	3.62e-01	92.0%	74.5%
4409482	3158.1.1.2 ↗	beta barrels › uncharacterized protein RUMGNA_01417 › uncharacterized protein RUMGNA_01417 › uncharacterized protein RUMGNA_01417 › DUF2777	0.53	25.0	3.50e-01	91.3%	90.7%
3954133	2005.1.1.3 ↗	a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › Usp	0.51	30.0	3.11e-01	92.7%	59.3%
4979310	2.1.1.0 ↗	beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein	0.50	24.0	3.16e-01	94.7%	84.0%

D5 medium residues 685-862_932-956

PDB

Domain cluster: rep: IMGVR_UViG_3300009616_000257-3300009616-Ga0116111_100275611__D486-632

Pfam (4)

Accession	Name	Score	E-value	Q cov	HMM cov
PF03291.23 best	mRNA_G-N7_MeTrfase	86.4	2.80e-24	97.0%	50.5%
PF13489.13	Methyltransf_23	33.3	5.50e-08	89.7%	66.5%
PF08241.19	Methyltransf_11	26.2	1.40e-05	66.5%	100.0%
PF08242.19	Methyltransf_12	31.6	3.10e-07	65.5%	100.0%

D6 medium residues 863-931_957-1015

PDB

Domain cluster: representative

CATH (1)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4r03A00	2.40.128.720	Mainly Beta › Beta Barrel › Lipocalin ›	0.52	30.0	3.29e-01	81.2%	67.9%

ECOD (2)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
2702891	2003.1.5.28 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › mRNA_G-N7_MeTrfase	0.69	64.0	4.93e-01	99.2%	47.5%
None	—		0.66	62.0	4.68e-01	100.0%	48.8%