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putative_non-structural_protein_1
Euk-VirSkunk_amdoparvovirus
putative_non-structural_protein_1__YP_009361877__Skunk_amdoparvovirus__1961072
Identity
- Accession:
- YP_009361877 ↗
- Protein ID:
- putative_non-structural_protein_1
- Kingdom:
- euk
Quality
70.0
mean pLDDT
Taxonomy
Shotokuvirae›
Cossaviricota›
Quintoviricetes›
Piccovirales›
Parvoviridae›
Amdoparvovirus›
Skunk_amdoparvovirus
TaxID: 1961072
Cluster
View cluster (4 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 425-583
Domain cluster:
rep: MN062720.1__QDP45567.1__SEA_FUZZBUSTER_83__00083__D568-722_747-764
Pfam (2)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF01057.24 best | Parvo_NS1 | 187.1 | 4.70e-55 | 98.7% | 58.3% |
| PF19263.6 | DUF5906 | 31.1 | 4.40e-07 | 65.4% | 91.1% |
D2
medium
residues 57-76_209-261
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF12433.15 best | PV_NSP1 | 65.9 | 4.80e-18 | 86.3% | 68.3% |
CATH (10)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1l8dA00 | 1.10.287.510 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.63 | 37.0 | 3.30e-01 | 72.6% | 39.8% |
| 3vbbE01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.61 | 38.0 | 3.21e-01 | 72.6% | 38.7% |
| 2nr9A00 | 1.20.1540.10 | Mainly Alpha › Up-down Bundle › Rhomboid-like fold › Rhomboid-like | 0.61 | 43.0 | 3.17e-01 | 74.0% | 48.4% |
| 7kh2B01 | 3.20.20.10 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Alanine racemase | 0.59 | 41.0 | 2.84e-01 | 72.6% | 99.2% |
| 1u5tB02 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.58 | 36.0 | 3.72e-01 | 72.6% | 65.2% |
| 1rxqD00 | 1.20.120.450 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › dinb family like domain | 0.57 | 40.0 | 3.04e-01 | 72.6% | 60.9% |
| 2cufA01 | 1.10.10.60 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like | 0.57 | 39.0 | 3.93e-01 | 71.2% | 81.9% |
| 1tx3D00 | 3.40.600.10 | Alpha Beta › 3-Layer(aba) Sandwich › ECO RV Endonuclease; Chain A › DNA mismatch repair MutH/Restriction endonuclease, type II | 0.54 | 47.0 | 3.32e-01 | 100.0% | 87.3% |
| 2wg7A00 | 1.20.90.10 | Mainly Alpha › Up-down Bundle › Phospholipase A2 › Phospholipase A2 domain | 0.51 | 44.0 | 3.81e-01 | 100.0% | 93.4% |
| 4d79A00 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.51 | 39.0 | 2.74e-01 | 83.6% | 86.4% |
ECOD (11)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3227090 | 5069.1.1.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes | 0.59 | 41.0 | 3.13e-01 | 72.6% | 92.0% |
| 3440194 | 601.3.1.4 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › PTPLA | 0.59 | 40.0 | 2.95e-01 | 71.2% | 55.8% |
| 4048384 | 102.1.4.2 ↗ | alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › Nop C-terminal domain › Transposase_20 | 0.58 | 39.0 | 3.25e-01 | 71.2% | 72.6% |
| 3349750 | 3567.1.1.75 ↗ | a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer › PTPLA | 0.57 | 39.0 | 2.91e-01 | 71.2% | 57.1% |
| 4946343 | 620.1.1.0 ↗ | alpha bundles › YfiT-like putative metal-dependent hydrolases › YfiT-like putative metal-dependent hydrolases › YfiT-like putative metal-dependent hydrolases | 0.55 | 38.0 | 3.02e-01 | 72.6% | 57.3% |
| 3291252 | 4107.1.1.1 ↗ | alpha arrays › Jann2411-like › Jann2411-like › Jann2411-like › ABATE,zf-CGNR | 0.54 | 37.0 | 2.90e-01 | 72.6% | 38.3% |
| 4244236 | 3681.1.1.0 ↗ | a+b complex topology › Helical hairpin insertion in E. coli DNA-directed RNA polymerase beta subunit › Helical hairpin insertion in E. coli DNA-directed RNA polymerase beta subunit › Helical hairpin insertion in E. coli DNA-directed RNA polymerase beta subunit | 0.54 | 40.0 | 3.50e-01 | 83.6% | 52.7% |
| 3489391 | 5051.1.1.0 ↗ | alpha complex topology › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like | 0.53 | 36.0 | 2.25e-01 | 72.6% | 57.9% |
| 3483410 | 7516.1.1.0 ↗ | a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases | 0.53 | 45.0 | 2.96e-01 | 95.9% | 62.2% |
| 4887928 | 5063.1.1.1 ↗ | alpha bundles › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK › PSI_PSAK | 0.52 | 35.0 | 3.65e-01 | 71.2% | 77.1% |
| 3245706 | 5057.1.1.1 ↗ | alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neur_chan_memb | 0.51 | 35.0 | 2.85e-01 | 71.2% | 89.2% |
D3
medium
residues 77-208
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF12475.14 best | Amdo_NSP_1-3 | 83.0 | 1.80e-23 | 38.6% | 85.2% |
CATH (27)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4bbyA05 | 3.30.300.330 | Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › | 0.76 | 48.0 | 5.32e-01 | 86.4% | 78.7% |
| 3c19A01 | 3.30.70.1380 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Transcriptional regulatory protein pf0864 domain like | 0.75 | 42.0 | 4.79e-01 | 97.0% | 72.7% |
| 4djbA00 | 3.30.70.2870 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Mastadenovirus E4 ORF3 | 0.72 | 51.0 | 5.35e-01 | 99.2% | 81.4% |
| 1pu1A00 | 3.30.300.100 | Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › MTH677-like | 0.71 | 47.0 | 5.44e-01 | 77.3% | 96.7% |
| 4oycB00 | 3.30.300.30 | Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › ANL, C-terminal domain | 0.67 | 43.0 | 5.08e-01 | 99.2% | 95.5% |
| 1ml8A02 | 3.30.300.20 | Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › K homology (KH) domain | 0.67 | 46.0 | 5.22e-01 | 96.2% | 95.9% |
| 3n0vA01 | 3.30.70.260 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain | 0.67 | 38.0 | 4.64e-01 | 97.7% | 88.1% |
| 2e8eA00 | 3.30.300.20 | Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › K homology (KH) domain | 0.64 | 46.0 | 4.68e-01 | 100.0% | 74.2% |
| 3e3vA03 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.63 | 23.0 | 3.48e-01 | 82.6% | 76.8% |
| 1lqlA02 | 3.30.300.20 | Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › K homology (KH) domain | 0.63 | 46.0 | 5.07e-01 | 100.0% | 97.1% |
| 4gs5A02 | 3.30.300.30 | Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › ANL, C-terminal domain | 0.63 | 40.0 | 4.39e-01 | 100.0% | 79.0% |
| 2pn2A00 | 3.30.300.20 | Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › K homology (KH) domain | 0.61 | 45.0 | 4.52e-01 | 100.0% | 75.2% |
| 2onfA01 | 3.30.300.20 | Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › K homology (KH) domain | 0.60 | 47.0 | 4.72e-01 | 100.0% | 81.3% |
| 2d7vB00 | 3.30.300.20 | Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › K homology (KH) domain | 0.58 | 47.0 | 4.45e-01 | 100.0% | 73.9% |
| 1yq3C02 | 1.20.1300.10 | Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit | 0.58 | 41.0 | 4.44e-01 | 87.9% | 88.0% |
| 4akrA02 | 3.90.1150.210 | Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › F-actin capping protein, beta subunit | 0.55 | 40.0 | 3.89e-01 | 98.5% | 67.3% |
| 2ql8A00 | 3.30.300.20 | Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › K homology (KH) domain | 0.55 | 45.0 | 4.49e-01 | 100.0% | 84.3% |
| 4mt4A00 | 1.20.1600.10 | Mainly Alpha › Up-down Bundle › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) | 0.53 | 47.0 | 3.23e-01 | 99.2% | 88.1% |
| 4ysxC00 | 1.20.1300.10 | Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit | 0.53 | 39.0 | 3.80e-01 | 84.8% | 68.6% |
| 1ek9A00 | 1.20.1600.10 | Mainly Alpha › Up-down Bundle › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) | 0.52 | 39.0 | 2.71e-01 | 76.5% | 92.5% |
| 2py5A05 | 4.10.80.20 | Few Secondary Structures › Irregular › Rhinovirus 14, subunit 4 › DNA polymerase; domain 5 | 0.52 | 13.0 | 2.54e-01 | 87.9% | 73.3% |
| 4wsqB00 | 1.10.510.10 | Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 | 0.52 | 41.0 | 3.08e-01 | 81.8% | 45.8% |
| 2ivxB01 | 1.10.472.10 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like | 0.52 | 42.0 | 4.12e-01 | 100.0% | 80.7% |
| 6hj2A00 | 1.10.565.10 | Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor | 0.51 | 45.0 | 3.62e-01 | 98.5% | 57.3% |
| 2l8oA00 | 3.30.530.20 | Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain | 0.50 | 38.0 | 3.70e-01 | 78.8% | 90.3% |
| 3amiA02 | 3.30.830.10 | Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like | 0.50 | 45.0 | 3.97e-01 | 100.0% | 81.4% |
| 3q9tA02 | 3.30.560.10 | Alpha Beta › 2-Layer Sandwich › Glucose Oxidase; domain 3 › Glucose Oxidase, domain 3 | 0.50 | 44.0 | 3.40e-01 | 100.0% | 78.0% |
ECOD (25)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5050420 | 324.1.1.0 ↗ | a+b two layers › OsmC-like › OsmC-like › OsmC-like | 0.71 | 49.0 | 5.14e-01 | 99.2% | 76.7% |
| 5078624 | 878.1.1.1 ↗ | a+b two layers › Hypothetical protein MTH677 › Hypothetical protein MTH677 › Hypothetical protein MTH677 › DUF3194 | 0.70 | 49.0 | 5.38e-01 | 72.0% | 89.5% |
| 3943661 | 304.5.1.13 ↗ | a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like › DUF3574 | 0.68 | 44.0 | 4.95e-01 | 97.7% | 85.0% |
| 5072826 | 878.1.1.0 ↗ | a+b two layers › Hypothetical protein MTH677 › Hypothetical protein MTH677 › Hypothetical protein MTH677 | 0.68 | 45.0 | 5.29e-01 | 72.0% | 100.0% |
| 5056801 | 324.1.1.1 ↗ | a+b two layers › OsmC-like › OsmC-like › OsmC-like › OsmC | 0.68 | 48.0 | 4.94e-01 | 72.7% | 80.0% |
| 3305599 | 304.55.1.20 ↗ | a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Origin of replication-binding domains › Helitron_like_N, REP_ORF2-G2P | 0.66 | 43.0 | 5.06e-01 | 97.7% | 95.6% |
| 3655568 | 304.20.1.0 ↗ | a+b two layers › Alpha-beta plaits › PAP/Archaeal CCA-adding enzyme, C-terminal domain › PAP/Archaeal CCA-adding enzyme, C-terminal domain | 0.64 | 45.0 | 4.59e-01 | 100.0% | 75.2% |
| 3825753 | 304.20.1.1 ↗ | a+b two layers › Alpha-beta plaits › PAP/Archaeal CCA-adding enzyme, C-terminal domain › PAP/Archaeal CCA-adding enzyme, C-terminal domain › PAP_RNA-bind | 0.64 | 43.0 | 4.58e-01 | 100.0% | 79.1% |
| 4301550 | 327.5.1.2 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › a+b domain in acetyl-CoA synthetase-like proteins › a+b domain in acetyl-CoA synthetase-like proteins › AMP-binding_C | 0.64 | 40.0 | 4.42e-01 | 100.0% | 79.0% |
| 3778175 | 5052.1.1.1 ↗ | alpha complex topology › Proton glutamate symport protein › Proton glutamate symport protein › Proton glutamate symport protein › SDF | 0.63 | 52.0 | 3.61e-01 | 89.4% | 29.8% |
| 5075397 | 324.1.1.1 ↗ | a+b two layers › OsmC-like › OsmC-like › OsmC-like › OsmC | 0.63 | 45.0 | 4.60e-01 | 73.5% | 80.8% |
| 4169399 | 304.14.1.1 ↗ | a+b two layers › Alpha-beta plaits › Sporulation related repeat (SPOR) › Sporulation related repeat (SPOR) › SPOR | 0.62 | 35.0 | 4.25e-01 | 94.7% | 88.6% |
| 3627810 | 3246.1.1.1 ↗ | few secondary structure elements › Disulfide-rich domain in A Disintegrin And Metalloprotease (ADAM) domain-containing proteins › Disulfide-rich domain in A Disintegrin And Metalloprotease (ADAM) domain-containing proteins › Disulfide-rich domain in A Disintegrin And Metalloprotease (ADAM) domain-containing proteins › ADAM_CR | 0.62 | 33.0 | 3.36e-01 | 91.7% | 49.6% |
| 3290246 | 327.5.1.0 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › a+b domain in acetyl-CoA synthetase-like proteins › a+b domain in acetyl-CoA synthetase-like proteins | 0.62 | 43.0 | 4.53e-01 | 97.0% | 80.0% |
| 4992024 | 5069.1.3.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits | 0.60 | 47.0 | 4.87e-01 | 94.7% | 90.0% |
| 3960213 | 304.156.1.5 ↗ | a+b two layers › Alpha-beta plaits › DNA translocase FtsK N-terminal domain › DNA translocase FtsK N-terminal domain › PF31086 | 0.60 | 44.0 | 4.69e-01 | 99.2% | 87.0% |
| 3782802 | 304.15.1.0 ↗ | a+b two layers › Alpha-beta plaits › Viral DNA-binding domain › Viral DNA-binding domain | 0.59 | 47.0 | 4.25e-01 | 93.2% | 61.1% |
| 4620055 | 604.39.1.0 ↗ | alpha bundles › Spectrin repeat-like › S-component of energy-coupling factor (ECF) transporters › S-component of energy-coupling factor (ECF) transporters | 0.59 | 55.0 | 4.45e-01 | 100.0% | 57.1% |
| 4972025 | 1075.1.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain | 0.58 | 45.0 | 3.94e-01 | 83.3% | 78.0% |
| 4024875 | 4250.1.1.1 ↗ | alpha bundles › Duffy-binding-like domain, N-terminal subdomain › Duffy-binding-like domain, N-terminal subdomain › Duffy-binding-like domain, N-terminal subdomain › Duffy_binding | 0.55 | 45.0 | 4.18e-01 | 88.6% | 94.1% |
| 3194847 | 3343.1.1.2 ↗ | alpha complex topology › gamma-tubulin complex protein 4 (GCP4) › gamma-tubulin complex protein 4 (GCP4) › gamma-tubulin complex protein 4 (GCP4) › GCP_C_terminal,GCP_N_terminal | 0.54 | 40.0 | 2.62e-01 | 79.5% | 35.7% |
| 1180647 | 205.1.1.35 ↗ | a+b two layers › 4Fe-4S ferredoxin › 4Fe-4S ferredoxin › 4Fe-4S ferredoxin › Fer4+Fer4_7 | 0.53 | 29.0 | 3.52e-01 | 85.6% | 88.2% |
| 2718723 | 228.1.1.1 ↗ | a+b three layers › Fe,Mn superoxide dismutase (SOD)-C › Fe,Mn superoxide dismutase (SOD)-C › Fe,Mn superoxide dismutase (SOD)-C › Sod_Fe_C | 0.52 | 27.0 | 3.39e-01 | 100.0% | 86.1% |
| 3517620 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.52 | 40.0 | 3.02e-01 | 81.8% | 33.8% |
| 4160692 | 171.1.1.1 ↗ | alpha arrays › RNase III catalytic domain-like › RNase III catalytic domain-like › RNase III catalytic domain-like › Ribonuclease_3 | 0.51 | 39.0 | 3.32e-01 | 81.1% | 81.8% |
D4
medium
residues 324-377
Domain cluster:
rep: NS1__YP_009507341__Gray_fox_amdovirus__1093101__D336-385
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF01057.24 best | Parvo_NS1 | 31.0 | 1.80e-07 | 100.0% | 19.2% |