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putative_non-structural_protein_NS5
Euk-VirTamana_bat_virus
putative_non-structural_protein_NS5__NP_776035__Tamana_bat_virus__161675
Identity
- Accession:
- NP_776035 ↗
- Protein ID:
- putative_non-structural_protein_NS5
- Kingdom:
- euk
Quality
83.1
mean pLDDT
Taxonomy
Orthornavirae›
Kitrinoviricota›
Flasuviricetes›
Amarillovirales›
Flaviviridae›
Orthoflavivirus›
Tamana_bat_virus
TaxID: 161675
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 31-214
Domain cluster:
rep: NC_049343.1__YP_009949298.1__HYO68_gp42__00042__D42-275
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF01728.26 best | FtsJ | 36.5 | 7.00e-09 | 88.0% | 70.7% |
D2
medium
residues 229-274_446-456_504-572
Domain cluster:
representative
D3
medium
residues 275-297_457-475_653-696
Domain cluster:
representative
D4
medium
residues 298-445
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00972.26 best | Flavi_NS5 | 68.9 | 4.90e-19 | 99.3% | 31.7% |
ECOD (9)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1279063 | 304.48.1.13 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Flavi_NS5 | 0.92 | 89.0 | 6.08e-01 | 100.0% | 35.0% |
| 4875416 | 304.48.1.13 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Flavi_NS5 | 0.84 | 76.0 | 5.39e-01 | 100.0% | 35.7% |
| 5366 | 304.48.1.15 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RdRP_3 | 0.81 | 76.0 | 5.42e-01 | 100.0% | 38.2% |
| 4871000 | 304.48.1.8 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RdRP_1 | 0.79 | 73.0 | 5.94e-01 | 99.3% | 61.1% |
| 1875037 | 304.48.1.8 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RdRP_1 | 0.78 | 73.0 | 5.29e-01 | 100.0% | 41.8% |
| 1173784 | 304.48.1.8 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RdRP_1 | 0.76 | 71.0 | 5.19e-01 | 99.3% | 42.3% |
| 1699894 | 304.48.2.2 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › 'palm' domain in birnaviruse RNA-dependent RNA polymerase › Permu_RdRp_palm | 0.74 | 69.0 | 4.61e-01 | 100.0% | 28.6% |
| 3938749 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.70 | 60.0 | 4.47e-01 | 92.6% | 38.9% |
| 3651623 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.64 | 55.0 | 4.62e-01 | 98.0% | 55.1% |
D5
medium
residues 476-503_573-652
Domain cluster:
rep: RNA-dependent_RNA_polymerase_NS5__YP_009259365__Quang_Binh_virus__643132__D492-530_608-683
CATH (68)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1s48A04 | 3.30.70.270 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain | 0.81 | 66.0 | 6.60e-01 | 100.0% | 82.9% |
| 1gx5A03 | 3.30.70.270 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain | 0.77 | 71.0 | 6.80e-01 | 100.0% | 86.1% |
| 3h5xA03 | 3.30.70.270 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain | 0.75 | 67.0 | 6.60e-01 | 98.1% | 89.7% |
| 1khvA03 | 3.30.70.270 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain | 0.72 | 67.0 | 6.30e-01 | 100.0% | 86.2% |
| 2dgxA01 | 3.30.70.330 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain | 0.70 | 50.0 | 5.68e-01 | 79.6% | 100.0% |
| 6j6ga00 | 3.30.70.330 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain | 0.70 | 50.0 | 5.54e-01 | 81.5% | 95.2% |
| 3s1tA02 | 3.30.70.260 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain | 0.70 | 50.0 | 5.67e-01 | 80.6% | 100.0% |
| 2a3jA00 | 3.30.70.330 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain | 0.69 | 52.0 | 5.45e-01 | 85.2% | 87.5% |
| 1konA03 | 3.30.70.980 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › YebC, transcriptional regulation domain | 0.68 | 45.0 | 5.23e-01 | 86.1% | 97.3% |
| 2la4A00 | 3.30.70.330 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain | 0.67 | 47.0 | 4.85e-01 | 88.0% | 77.2% |
| 1hi8A03 | 3.30.70.1600 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.66 | 61.0 | 5.13e-01 | 100.0% | 81.8% |
| 4hkqA01 | 3.30.70.270 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain | 0.66 | 57.0 | 5.19e-01 | 100.0% | 70.1% |
| 4ol8A01 | 3.30.70.270 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain | 0.65 | 52.0 | 4.80e-01 | 100.0% | 67.4% |
| 3n01A00 | 3.30.70.2470 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Protein-tyrosine phosphatase receptor IA-2 ectodomain | 0.65 | 49.0 | 5.38e-01 | 91.7% | 100.0% |
| 3pjxA01 | 3.30.70.270 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain | 0.65 | 59.0 | 4.94e-01 | 100.0% | 72.9% |
| 7e6gA01 | 3.30.70.270 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain | 0.64 | 58.0 | 5.21e-01 | 100.0% | 88.6% |
| 3jcmH04 | 3.30.70.870 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Elongation Factor G (Translational Gtpase), domain 3 | 0.64 | 44.0 | 5.03e-01 | 91.7% | 100.0% |
| 5xgbA02 | 3.30.70.270 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain | 0.64 | 58.0 | 4.88e-01 | 100.0% | 73.7% |
| 6tznA01 | 3.30.70.330 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain | 0.63 | 49.0 | 4.98e-01 | 83.3% | 98.1% |
| 4er8A00 | 3.30.70.1290 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Transposase IS200-like | 0.63 | 50.0 | 4.40e-01 | 86.1% | 90.9% |
| 3c1mA02 | 3.30.2130.10 | Alpha Beta › 2-Layer Sandwich › VC0802-like › VC0802-like | 0.63 | 55.0 | 4.77e-01 | 94.4% | 73.2% |
| 5t0oA02 | 3.30.70.1430 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Multidrug efflux transporter AcrB pore domain | 0.62 | 51.0 | 5.27e-01 | 89.8% | 92.2% |
| 2r7rA04 | 3.30.70.2480 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.62 | 57.0 | 4.99e-01 | 99.1% | 86.0% |
| 4mt1A06 | 3.30.70.1430 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Multidrug efflux transporter AcrB pore domain | 0.62 | 48.0 | 5.00e-01 | 83.3% | 100.0% |
| 4mt1A02 | 3.30.70.1430 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Multidrug efflux transporter AcrB pore domain | 0.62 | 48.0 | 4.97e-01 | 84.3% | 92.2% |
| 2mq8A00 | 3.30.70.600 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S10 | 0.61 | 48.0 | 4.79e-01 | 83.3% | 88.4% |
| 2c5sA01 | 3.30.2130.30 | Alpha Beta › 2-Layer Sandwich › VC0802-like › | 0.61 | 48.0 | 4.17e-01 | 84.3% | 92.3% |
| 5yuyA01 | 3.30.70.270 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain | 0.61 | 50.0 | 4.85e-01 | 88.0% | 80.3% |
| 6lpnA03 | 3.30.70.2190 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.61 | 48.0 | 4.80e-01 | 86.1% | 92.1% |
| 1r89A03 | 3.30.70.590 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Poly(A) polymerase predicted RNA binding domain | 0.60 | 54.0 | 5.03e-01 | 100.0% | 90.3% |
| 3gqcC01 | 3.30.70.270 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain | 0.60 | 49.0 | 4.52e-01 | 87.0% | 71.5% |
| 2fiuA00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.60 | 47.0 | 4.94e-01 | 82.4% | 98.9% |
| 1q2lA02 | 3.30.830.10 | Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like | 0.59 | 50.0 | 3.92e-01 | 91.7% | 85.3% |
| 4l3tA04 | 3.30.830.10 | Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like | 0.59 | 47.0 | 3.57e-01 | 86.1% | 74.0% |
| 3oq2A00 | 3.30.70.240 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.59 | 43.0 | 4.48e-01 | 87.0% | 83.8% |
| 3tviA02 | 3.30.2130.10 | Alpha Beta › 2-Layer Sandwich › VC0802-like › VC0802-like | 0.59 | 50.0 | 4.43e-01 | 94.4% | 73.0% |
| 1m1hA01 | 3.30.70.940 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › NusG, N-terminal domain | 0.59 | 46.0 | 4.73e-01 | 94.4% | 91.0% |
| 1wvqA00 | 3.40.1520.10 | Alpha Beta › 3-Layer(aba) Sandwich › hypothetical protein tt1634 › Ta1353-like | 0.58 | 52.0 | 4.58e-01 | 99.1% | 76.7% |
| 1ctfA00 | 3.30.1390.10 | Alpha Beta › 2-Layer Sandwich › Ribosomal Protein L30; Chain: A, › Ribosomal protein L7/L12, C-terminal domain/Adaptor protein ClpS | 0.58 | 36.0 | 4.29e-01 | 79.6% | 97.1% |
| 1rlhA02 | 3.40.1520.10 | Alpha Beta › 3-Layer(aba) Sandwich › hypothetical protein tt1634 › Ta1353-like | 0.58 | 45.0 | 4.65e-01 | 81.5% | 100.0% |
| 2rkvA01 | 3.30.559.10 | Alpha Beta › 2-Layer Sandwich › Chloramphenicol Acetyltransferase › Chloramphenicol acetyltransferase-like domain | 0.58 | 46.0 | 3.77e-01 | 88.0% | 93.5% |
| 4x0qA03 | 3.30.70.370 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.58 | 51.0 | 4.70e-01 | 99.1% | 95.8% |
| 1q8bA00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.58 | 44.0 | 4.68e-01 | 81.5% | 94.6% |
| 3b8pA00 | 3.30.1890.10 | Alpha Beta › 2-Layer Sandwich › Bacterial polysaccharide co-polymerase-like › FepE-like | 0.58 | 45.0 | 3.64e-01 | 83.3% | 97.1% |
| 3pm9A03 | 3.30.70.2190 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.57 | 50.0 | 4.81e-01 | 94.4% | 90.9% |
| 3h7hB00 | 3.30.70.940 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › NusG, N-terminal domain | 0.57 | 44.0 | 4.60e-01 | 94.4% | 93.7% |
| 4mt1A03 | 3.30.70.1320 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Multidrug efflux transporter AcrB pore domain like | 0.57 | 48.0 | 4.99e-01 | 91.7% | 100.0% |
| 4l3tA03 | 3.30.830.10 | Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like | 0.57 | 46.0 | 3.66e-01 | 88.0% | 79.2% |
| 1mwqA00 | 3.30.70.1060 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Dimeric alpha+beta barrel | 0.57 | 44.0 | 4.56e-01 | 82.4% | 95.0% |
| 1iujA00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.57 | 44.0 | 4.53e-01 | 83.3% | 94.1% |
| 3mcsA00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.57 | 49.0 | 3.97e-01 | 97.2% | 75.9% |
| 3w9iD03 | 3.30.70.1320 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Multidrug efflux transporter AcrB pore domain like | 0.57 | 47.0 | 4.83e-01 | 90.7% | 98.1% |
| 6s6yD01 | 3.30.70.520 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.57 | 44.0 | 3.93e-01 | 84.3% | 81.5% |
| 3lo3A00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.56 | 46.0 | 4.85e-01 | 88.9% | 100.0% |
| 1f5aA01 | 3.30.70.590 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Poly(A) polymerase predicted RNA binding domain | 0.56 | 48.0 | 4.85e-01 | 93.5% | 99.1% |
| 5t0oA03 | 3.30.70.1320 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Multidrug efflux transporter AcrB pore domain like | 0.56 | 46.0 | 4.74e-01 | 89.8% | 100.0% |
| 3hx9B00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.56 | 43.0 | 4.46e-01 | 82.4% | 96.9% |
| 4dn9B00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.55 | 43.0 | 4.48e-01 | 83.3% | 93.8% |
| 3zfvA02 | 3.30.70.1900 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.55 | 43.0 | 3.83e-01 | 83.3% | 92.9% |
| 3m84A02 | 3.90.650.10 | Alpha Beta › Alpha-Beta Complex › Phosphoribosyl-aminoimidazole Synthetase; Chain A, domain 2 › PurM-like C-terminal domain | 0.54 | 48.0 | 4.10e-01 | 99.1% | 100.0% |
| 1t94B02 | 3.30.70.270 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain | 0.53 | 42.0 | 4.14e-01 | 86.1% | 91.6% |
| 2hg2A01 | 3.40.605.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 | 0.53 | 40.0 | 3.09e-01 | 83.3% | 61.9% |
| 1iq4A00 | 3.30.1440.10 | Alpha Beta › 2-Layer Sandwich › 50s Ribosomal Protein L5; Chain: A, › Ribosomal protein L5 | 0.53 | 41.0 | 3.55e-01 | 85.2% | 72.6% |
| 4oq1A01 | 2.60.40.4180 | Mainly Beta › Sandwich › Immunoglobulin-like › | 0.52 | 41.0 | 4.03e-01 | 86.1% | 93.4% |
| 1ry9A00 | 3.30.1460.10 | Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, › | 0.52 | 36.0 | 3.37e-01 | 71.3% | 100.0% |
| 4f67A01 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.51 | 41.0 | 4.20e-01 | 88.0% | 89.6% |
| 3thxB04 | 1.10.1420.10 | Mainly Alpha › Orthogonal Bundle › MutS, DNA mismatch repair protein; Chain A, domain 3 › | 0.51 | 30.0 | 2.89e-01 | 75.0% | 48.4% |
| 3ldgA01 | 3.30.2130.30 | Alpha Beta › 2-Layer Sandwich › VC0802-like › | 0.51 | 40.0 | 3.37e-01 | 87.0% | 80.4% |
ECOD (66)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4875416 | 304.48.1.13 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Flavi_NS5 | 0.87 | 84.0 | 5.46e-01 | 100.0% | 47.2% |
| 1279063 | 304.48.1.13 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Flavi_NS5 | 0.84 | 76.0 | 4.81e-01 | 93.5% | 42.6% |
| 5366 | 304.48.1.15 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RdRP_3 | 0.81 | 73.0 | 4.77e-01 | 94.4% | 40.7% |
| 1875037 | 304.48.1.8 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RdRP_1 | 0.72 | 63.0 | 4.17e-01 | 91.7% | 41.0% |
| 3378851 | 304.7.1.2 ↗ | a+b two layers › Alpha-beta plaits › Protease propeptides/inhibitors › Protease propeptides/inhibitors › Inhibitor_I9 | 0.71 | 51.0 | 5.80e-01 | 84.3% | 100.0% |
| 4398030 | 304.117.1.1 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in YebC › Ferredoxin-like domain in YebC › Transcrip_reg | 0.70 | 44.0 | 5.01e-01 | 84.3% | 85.0% |
| 3441452 | 304.7.1.2 ↗ | a+b two layers › Alpha-beta plaits › Protease propeptides/inhibitors › Protease propeptides/inhibitors › Inhibitor_I9 | 0.70 | 50.0 | 5.50e-01 | 85.2% | 94.1% |
| 3442371 | 304.7.1.0 ↗ | a+b two layers › Alpha-beta plaits › Protease propeptides/inhibitors › Protease propeptides/inhibitors | 0.69 | 47.0 | 5.25e-01 | 84.3% | 88.2% |
| 3932926 | 304.9.1.0 ↗ | a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD | 0.69 | 52.0 | 5.78e-01 | 88.9% | 100.0% |
| 3531239 | 304.151.1.1 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin-like domain of receptor-type protein tyrosine phosphatase › Ferredoxin-like domain of receptor-type protein tyrosine phosphatase › Receptor_IA-2 | 0.68 | 56.0 | 5.93e-01 | 92.6% | 100.0% |
| 3818981 | 304.7.1.2 ↗ | a+b two layers › Alpha-beta plaits › Protease propeptides/inhibitors › Protease propeptides/inhibitors › Inhibitor_I9 | 0.68 | 48.0 | 5.42e-01 | 83.3% | 98.8% |
| 4968681 | 304.57.1.0 ↗ | a+b two layers › Alpha-beta plaits › Rpp14/Pop5-like › Rpp14/Pop5-like | 0.68 | 51.0 | 5.35e-01 | 84.3% | 87.0% |
| 3742864 | 304.8.1.0 ↗ | a+b two layers › Alpha-beta plaits › ACT-like › ACT-like | 0.67 | 47.0 | 4.67e-01 | 89.8% | 70.0% |
| 3936671 | 304.9.1.0 ↗ | a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD | 0.67 | 52.0 | 5.50e-01 | 88.0% | 92.6% |
| 4024206 | 304.9.1.0 ↗ | a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD | 0.67 | 53.0 | 5.32e-01 | 99.1% | 83.6% |
| 3927592 | 304.9.1.0 ↗ | a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD | 0.66 | 52.0 | 4.94e-01 | 84.3% | 70.8% |
| 4600602 | 304.120.1.6 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in ThiI › Ferredoxin-like domain in ThiI › ThiI_fer | 0.66 | 47.0 | 5.27e-01 | 80.6% | 100.0% |
| 1873954 | 304.8.1.2 ↗ | a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › ACT | 0.65 | 50.0 | 5.35e-01 | 91.7% | 93.7% |
| 3744422 | 304.9.1.33 ↗ | a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › xRRM | 0.65 | 54.0 | 5.19e-01 | 91.7% | 92.8% |
| 4215083 | 304.48.1.10 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › IMS | 0.64 | 56.0 | 5.27e-01 | 100.0% | 79.2% |
| 4403875 | 304.28.1.1 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › ACR_tran | 0.64 | 51.0 | 5.46e-01 | 85.2% | 100.0% |
| 3947945 | 304.48.1.14 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › GGDEF | 0.64 | 58.0 | 4.67e-01 | 100.0% | 61.5% |
| 3973625 | 304.28.1.0 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain | 0.64 | 50.0 | 5.27e-01 | 83.3% | 100.0% |
| 3511024 | 304.28.1.1 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › ACR_tran | 0.64 | 53.0 | 5.51e-01 | 89.8% | 100.0% |
| 4029341 | 304.9.1.0 ↗ | a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD | 0.64 | 47.0 | 5.18e-01 | 81.5% | 100.0% |
| 3191211 | 304.8.1.21 ↗ | a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › ACT_9 | 0.63 | 48.0 | 5.27e-01 | 90.7% | 100.0% |
| 3626410 | 304.9.1.0 ↗ | a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD | 0.63 | 52.0 | 5.24e-01 | 88.9% | 100.0% |
| 3838673 | 304.28.1.1 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › ACR_tran | 0.63 | 49.0 | 5.32e-01 | 83.3% | 100.0% |
| 4363128 | 304.20.1.5 ↗ | a+b two layers › Alpha-beta plaits › PAP/Archaeal CCA-adding enzyme, C-terminal domain › PAP/Archaeal CCA-adding enzyme, C-terminal domain › tRNA_synt_2f | 0.63 | 50.0 | 3.90e-01 | 87.0% | 83.3% |
| 4148845 | 304.28.1.1 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › ACR_tran | 0.62 | 52.0 | 5.40e-01 | 89.8% | 97.0% |
| 3974782 | 304.28.1.1 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › ACR_tran | 0.62 | 51.0 | 5.41e-01 | 91.7% | 100.0% |
| 4031689 | 304.28.1.1 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › ACR_tran | 0.62 | 51.0 | 5.37e-01 | 88.0% | 100.0% |
| 3959043 | 862.1.1.0 ↗ | a+b complex topology › Prim-pol domain › Prim-pol domain › Prim-pol domain | 0.62 | 54.0 | 3.95e-01 | 100.0% | 59.1% |
| 3530700 | 4.1.1.331 ↗ | beta barrels › SH3 › SH3 › SH3 › DUF4708 | 0.62 | 46.0 | 5.11e-01 | 93.5% | 100.0% |
| 3838674 | 304.28.1.1 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › ACR_tran | 0.62 | 51.0 | 5.07e-01 | 88.0% | 98.2% |
| 3699926 | 304.51.1.0 ↗ | a+b two layers › Alpha-beta plaits › CRISPR transcript (pre-crRNA) processing endoribonuclease-related › CRISPR transcript (pre-crRNA) processing endoribonuclease-related | 0.62 | 48.0 | 4.58e-01 | 84.3% | 96.2% |
| 3838269 | 304.28.1.1 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › ACR_tran | 0.62 | 50.0 | 5.33e-01 | 88.0% | 100.0% |
| 4210141 | 304.48.1.10 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › IMS | 0.62 | 50.0 | 4.86e-01 | 87.0% | 79.2% |
| 3219038 | 304.28.1.0 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain | 0.61 | 48.0 | 3.95e-01 | 84.3% | 75.0% |
| 4954812 | 304.24.1.0 ↗ | a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like | 0.61 | 42.0 | 4.62e-01 | 88.9% | 90.6% |
| 4659364 | 304.55.2.7 ↗ | a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Transposase IS200-like › tRNA_synt_2f | 0.61 | 48.0 | 3.87e-01 | 87.0% | 92.0% |
| 3448748 | 304.27.1.2 ↗ | a+b two layers › Alpha-beta plaits › Formiminotransferase domain of formiminotransferase-cyclodeaminase. › Formiminotransferase domain of formiminotransferase-cyclodeaminase. › FTCD_N | 0.61 | 49.0 | 4.38e-01 | 86.1% | 72.0% |
| 3739302 | 304.48.1.10 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › IMS | 0.61 | 54.0 | 4.42e-01 | 97.2% | 81.0% |
| 3891889 | 11.1.1.633 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › KIAA0319 | 0.60 | 53.0 | 4.79e-01 | 96.3% | 80.0% |
| 3973622 | 304.28.1.0 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain | 0.60 | 49.0 | 4.93e-01 | 88.0% | 97.3% |
| 3322835 | 304.20.1.5 ↗ | a+b two layers › Alpha-beta plaits › PAP/Archaeal CCA-adding enzyme, C-terminal domain › PAP/Archaeal CCA-adding enzyme, C-terminal domain › tRNA_synt_2f | 0.60 | 48.0 | 3.85e-01 | 88.0% | 90.0% |
| 4424298 | 304.28.1.0 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain | 0.60 | 47.0 | 4.98e-01 | 83.3% | 100.0% |
| 3495499 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.59 | 53.0 | 3.86e-01 | 100.0% | 51.1% |
| 4970769 | 304.4.1.0 ↗ | a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel | 0.59 | 43.0 | 4.46e-01 | 83.3% | 82.0% |
| 5022225 | 304.20.1.4 ↗ | a+b two layers › Alpha-beta plaits › PAP/Archaeal CCA-adding enzyme, C-terminal domain › PAP/Archaeal CCA-adding enzyme, C-terminal domain › CAA_C | 0.59 | 52.0 | 4.39e-01 | 100.0% | 88.9% |
| 4987159 | 862.1.1.5 ↗ | a+b complex topology › Prim-pol domain › Prim-pol domain › Prim-pol domain › LigD_Prim-Pol | 0.59 | 51.0 | 3.97e-01 | 100.0% | 68.8% |
| 4373134 | 304.160.1.1 ↗ | a+b two layers › Alpha-beta plaits › Gas vesicle protein GvpF › Gas vesicle protein GvpF › GvpL_GvpF | 0.59 | 46.0 | 4.87e-01 | 86.1% | 95.8% |
| 4316367 | 304.55.2.7 ↗ | a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Transposase IS200-like › tRNA_synt_2f | 0.58 | 49.0 | 4.00e-01 | 94.4% | 92.6% |
| 3472646 | 304.9.1.0 ↗ | a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD | 0.58 | 45.0 | 4.59e-01 | 83.3% | 96.2% |
| 4970140 | 304.28.1.0 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain | 0.57 | 47.0 | 4.65e-01 | 89.8% | 100.0% |
| 3495137 | 304.9.1.1 ↗ | a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 | 0.57 | 50.0 | 4.88e-01 | 96.3% | 93.3% |
| 4031692 | 304.28.1.0 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain | 0.57 | 46.0 | 4.62e-01 | 88.9% | 97.3% |
| 4949617 | 210.1.3.0 ↗ | a+b four layers › Ntn/PP2C › Ntn › Class II glutamine amidotransferases | 0.55 | 40.0 | 3.41e-01 | 76.9% | 89.7% |
| 5044372 | 1036.1.1.1 ↗ | a+b two layers › 60S ribosomal export protein NMD3 a+b domain › 60S ribosomal export protein NMD3 a+b domain › 60S ribosomal export protein NMD3 a+b domain › NMD3 | 0.55 | 47.0 | 4.74e-01 | 97.2% | 92.7% |
| 4943248 | 4956.1.1.0 ↗ | a+b two layers › ferredoxin-like domain in yeast RNA-polymerase beta-prime subunit › ferredoxin-like domain in yeast RNA-polymerase beta-prime subunit › ferredoxin-like domain in yeast RNA-polymerase beta-prime subunit | 0.54 | 47.0 | 3.79e-01 | 98.1% | 54.1% |
| 3184299 | 304.4.1.0 ↗ | a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel | 0.53 | 46.0 | 4.35e-01 | 97.2% | 96.2% |
| 5037479 | 304.111.1.1 ↗ | a+b two layers › Alpha-beta plaits › PurM C-terminal domain-like › PurM C-terminal domain-like › AIRS_C | 0.53 | 47.0 | 3.99e-01 | 100.0% | 93.0% |
| 3797325 | 304.7.1.1 ↗ | a+b two layers › Alpha-beta plaits › Protease propeptides/inhibitors › Protease propeptides/inhibitors › Propep_M14 | 0.52 | 42.0 | 4.25e-01 | 92.6% | 86.4% |
| 5039548 | 264.1.1.1 ↗ | beta barrels › LigT-like › LigT-related › LigT-related › LigT_PEase | 0.51 | 45.0 | 3.88e-01 | 99.1% | 89.4% |
| 4998883 | 301.2.1.5 ↗ | a+b three layers › Bacillus chorismate mutase-like › PurM N-terminal domain-like › PurM N-terminal domain-like › AIRS_C | 0.51 | 46.0 | 3.30e-01 | 100.0% | 90.2% |
| 3499344 | 3914.1.1.2 ↗ | alpha bundles › TMEM16 lipid scramblase transmembrane domain › TMEM16 lipid scramblase transmembrane domain › TMEM16 lipid scramblase transmembrane domain › Anoctamin,Anoct_dimer | 0.51 | 45.0 | 2.70e-01 | 100.0% | 71.5% |
D6
medium
residues 697-803
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF20483.4 best | Flavi_NS5_thumb | 35.7 | 1.10e-08 | 100.0% | 66.5% |
CATH (1)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2vixA03 | 1.20.1280.240 | Mainly Alpha › Up-down Bundle › Monooxygenase › | 0.51 | 33.0 | 3.26e-01 | 71.0% | 61.1% |
ECOD (2)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| None | — | 0.84 | 80.0 | 6.27e-01 | 100.0% | 56.3% | |
| 3010831 | 4967.1.1.14 ↗ | alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › Flavi_NS5_thumb | 0.82 | 78.0 | 6.06e-01 | 100.0% | 55.2% |