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putative_papain-like_cysteine_peptidase

Euk-Vir

Acanthamoeba_polyphaga_moumouvirus

putative_papain-like_cysteine_peptidase__YP_007354383__Acanthamoeba_polyphaga_moumouvirus__1269028

Identity

Accession:
YP_007354383 ↗
Protein ID:
putative_papain-like_cysteine_peptidase
Kingdom:
euk

Quality

74.7 mean pLDDT

Taxonomy

Bamfordvirae› Nucleocytoviricota› Megaviricetes› Imitervirales› Mimiviridae› Moumouvirus› Acanthamoeba_polyphaga_moumouvirus

TaxID: 1269028

Cluster

View cluster (7 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 3-46_125-217
PDB
Domain cluster: rep: SRR1747018_scaffold_15_prodigal-single.1__X__X__00305__D17-144
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF08795.17 best DUF1796 44.6 1.90e-11 39.4% 25.3%
CATH (74)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2vptA00 3.40.50.1110 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › SGNH hydrolase 0.76 70.0 6.10e-01 100.0% 94.5%
6hfzA01 3.40.50.1110 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › SGNH hydrolase 0.74 68.0 5.80e-01 100.0% 83.2%
7zs9401 3.40.50.410 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › von Willebrand factor, type A domain 0.69 62.0 5.26e-01 98.5% 100.0%
2qvgA00 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.68 57.0 5.88e-01 100.0% 95.3%
5tqjA00 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.68 53.0 5.59e-01 100.0% 91.9%
3cfyA00 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.68 53.0 5.47e-01 100.0% 87.7%
2z4tA02 3.40.50.11120 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Sialyltransferase, N-terminal GT-B Rossman nucleotide-binding domain 0.67 58.0 4.94e-01 94.9% 93.3%
4lj3A00 3.20.20.450 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › EAL domain 0.67 59.0 4.79e-01 96.4% 84.4%
4fhzA00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.66 60.0 5.11e-01 100.0% 89.1%
4j1qA00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.65 52.0 3.65e-01 100.0% 27.6%
5ul3A01 3.40.50.280 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Cobalamin-binding domain 0.65 58.0 5.56e-01 100.0% 84.6%
4jc8A01 3.40.50.2060 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Sec1/Munc18 (SM) protein, domain 1 0.65 50.0 5.07e-01 89.1% 81.6%
4rz2B00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.65 59.0 4.79e-01 100.0% 94.5%
3hpxA01 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.65 52.0 4.03e-01 85.4% 68.8%
2bfdB02 3.40.50.920 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.64 52.0 5.39e-01 100.0% 93.6%
1jmkC01 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.64 59.0 5.45e-01 100.0% 89.5%
3kp1A04 3.40.50.280 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Cobalamin-binding domain 0.64 55.0 5.36e-01 100.0% 84.7%
1obbA00 3.90.1820.10 Alpha Beta › Alpha-Beta Complex › LDH C-terminal domain-like › AglA-like glucosidase 0.64 58.0 3.98e-01 100.0% 74.9%
6tm3A01 3.40.50.10280 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Methylene-tetrahydromethanopterin dehydrogenase, N-terminal domain 0.63 49.0 4.92e-01 100.0% 81.2%
1d5cA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.63 57.0 5.42e-01 100.0% 98.1%
1zd9A00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.63 57.0 5.36e-01 100.0% 95.2%
2b99C00 3.40.50.960 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Lumazine/riboflavin synthase 0.63 51.0 5.00e-01 100.0% 78.9%
3c3jA01 3.40.50.10490 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 0.63 57.0 5.05e-01 98.5% 69.6%
1xrsB02 3.40.50.280 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Cobalamin-binding domain 0.63 56.0 5.32e-01 100.0% 82.5%
4xymC03 3.40.50.261 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Succinyl-CoA synthetase domains 0.63 56.0 5.29e-01 100.0% 86.4%
2c42A02 3.40.50.920 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.62 49.0 4.68e-01 100.0% 72.6%
6dqoA00 3.40.50.360 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Flavodoxin domain 0.62 56.0 5.22e-01 100.0% 98.3%
4d02A02 3.40.50.360 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Flavodoxin domain 0.62 55.0 5.52e-01 100.0% 100.0%
1sulB00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.62 56.0 5.00e-01 100.0% 85.6%
1kjnA00 3.40.50.10160 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › MTH777-like 0.62 56.0 5.47e-01 100.0% 98.7%
3rf9B02 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.62 52.0 4.10e-01 91.2% 84.6%
1sqsA00 3.40.50.360 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Flavodoxin domain 0.62 55.0 4.67e-01 100.0% 75.3%
2ohhA02 3.40.50.360 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Flavodoxin domain 0.62 55.0 5.48e-01 100.0% 100.0%
3hlkB02 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.61 55.0 4.44e-01 100.0% 87.6%
6d92A01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.61 53.0 4.38e-01 93.4% 89.8%
1e5dA01 3.40.50.360 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Flavodoxin domain 0.61 55.0 5.47e-01 100.0% 99.3%
4a8jA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.61 55.0 4.34e-01 97.8% 71.5%
3lm3A01 3.20.20.510 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Uncharacterised protein PF12979, DUF3863 0.61 55.0 4.26e-01 100.0% 96.1%
5jipA01 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.61 51.0 4.42e-01 93.4% 93.4%
2im5A00 3.20.140.10 Alpha Beta › Alpha-Beta Barrel › nicotinate phosphoribosyltransferase › nicotinate phosphoribosyltransferase 0.61 48.0 3.49e-01 83.9% 85.6%
4fleA00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.61 55.0 4.89e-01 100.0% 94.9%
2q9uA02 3.40.50.360 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Flavodoxin domain 0.60 54.0 5.35e-01 100.0% 100.0%
1vlpA00 3.20.140.10 Alpha Beta › Alpha-Beta Barrel › nicotinate phosphoribosyltransferase › nicotinate phosphoribosyltransferase 0.60 48.0 3.40e-01 83.9% 83.0%
3bc9A02 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.60 51.0 4.06e-01 93.4% 95.9%
4cqbA02 3.20.20.140 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Metal-dependent hydrolases 0.60 55.0 4.26e-01 100.0% 98.0%
1b1cA00 3.40.50.360 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Flavodoxin domain 0.60 54.0 5.10e-01 100.0% 91.6%
5i7wA02 3.40.50.1100 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.60 42.0 4.56e-01 75.9% 86.8%
3x2fB01 3.40.50.1480 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Adenosylhomocysteinase-like 0.59 53.0 4.54e-01 100.0% 70.0%
7bvaA02 3.40.1190.10 Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Mur-like, catalytic domain 0.59 53.0 4.54e-01 100.0% 87.6%
1nni100 3.40.50.360 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Flavodoxin domain 0.59 53.0 4.95e-01 100.0% 93.5%
1ykgA00 3.40.50.360 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Flavodoxin domain 0.59 53.0 5.23e-01 99.3% 99.3%
3lloA00 3.30.750.24 Alpha Beta › 2-Layer Sandwich › Transcription Regulator spoIIAA › STAS domain 0.59 50.0 5.08e-01 97.1% 96.2%
3co5A00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.58 39.0 4.00e-01 74.5% 69.4%
8sp0A01 3.40.50.10140 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Toll/interleukin-1 receptor homology (TIR) domain 0.58 51.0 4.90e-01 100.0% 84.4%
3qfwB02 3.20.20.110 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Ribulose bisphosphate carboxylase, large subunit, C-terminal domain 0.58 53.0 4.35e-01 100.0% 82.0%
6aieA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.58 53.0 4.83e-01 99.3% 75.3%
3wqcA02 3.20.20.10 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Alanine racemase 0.58 49.0 4.19e-01 92.0% 79.4%
3e02A00 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.58 51.0 3.92e-01 95.6% 68.9%
2ww5A02 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.57 51.0 4.55e-01 100.0% 98.0%
7y11A01 3.40.525.10 Alpha Beta › 3-Layer(aba) Sandwich › Phosphatidylinositol Transfer Protein Sec14p › CRAL-TRIO lipid binding domain 0.57 49.0 4.40e-01 95.6% 74.5%
4c6rA00 3.40.50.10140 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Toll/interleukin-1 receptor homology (TIR) domain 0.57 51.0 4.90e-01 100.0% 96.9%
2hc9A01 3.40.50.10590 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Zn-dependent exopeptidases 0.56 45.0 4.32e-01 85.4% 89.6%
3umoA00 3.40.1190.20 Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase 0.55 49.0 3.86e-01 100.0% 88.0%
3nzeA00 3.40.50.1360 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.55 45.0 3.68e-01 87.6% 75.4%
3ugsB00 3.40.1180.10 Alpha Beta › 3-Layer(aba) Sandwich › Undecaprenyl pyrophosphate synthetase › Decaprenyl diphosphate synthase-like 0.55 43.0 3.82e-01 85.4% 70.7%
5dxfA02 3.40.50.2000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; 0.55 49.0 4.32e-01 100.0% 75.4%
2ftyA02 3.20.20.140 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Metal-dependent hydrolases 0.55 48.0 3.53e-01 99.3% 88.2%
2o7sA01 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.54 48.0 4.09e-01 99.3% 83.3%
3v75A01 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.53 47.0 3.83e-01 100.0% 83.6%
3s3tA00 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.53 38.0 3.78e-01 100.0% 69.7%
1amiA02 3.40.1060.10 Alpha Beta › 3-Layer(aba) Sandwich › Aconitase; Domain 2 › Aconitase, Domain 2 0.52 38.0 4.10e-01 95.6% 92.9%
6nffA02 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.51 46.0 3.53e-01 100.0% 66.9%
3fkfD00 3.40.30.10 Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin 0.51 36.0 3.70e-01 89.1% 73.7%
1ekeA01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.50 44.0 4.14e-01 96.4% 87.1%
ECOD (61)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3260634 129.1.1.0 ↗ alpha arrays › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like 0.69 63.0 5.44e-01 100.0% 84.3%
3260826 2003.1.1.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains 0.68 63.0 5.61e-01 100.0% 76.8%
3879317 2003.1.1.79 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › ISPD_C 0.68 63.0 5.99e-01 100.0% 88.7%
5049201 2006.1.6.0 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like 0.68 62.0 5.39e-01 100.0% 87.1%
3271658 2003.1.1.331 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › Methyltransf_12 0.67 61.0 4.18e-01 100.0% 30.4%
5035900 2004.1.1.73 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MMR_HSR1 0.67 61.0 5.71e-01 100.0% 91.8%
4547691 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.67 61.0 5.62e-01 100.0% 94.3%
3263363 2003.1.1.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains 0.66 61.0 5.43e-01 100.0% 78.4%
4386896 2002.1.1.120 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Radical_SAM 0.66 55.0 4.32e-01 89.8% 77.5%
3181115 2007.1.3.1 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg 0.65 57.0 5.40e-01 100.0% 80.6%
4054365 2002.5.1.1 ↗ a/b barrels › TIM beta/alpha-barrel › EAL domain › EAL domain › EAL 0.65 57.0 4.72e-01 95.6% 86.5%
3720917 7575.1.1.11 ↗ a/b three-layered sandwiches › Caspase-like › Caspase-like › Caspase-like › PF31181 0.65 59.0 5.13e-01 100.0% 93.3%
3271634 129.1.1.0 ↗ alpha arrays › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like 0.65 59.0 5.04e-01 100.0% 66.4%
5024826 2007.3.1.6 ↗ a/b three-layered sandwiches › Flavodoxin-like › Succinyl-CoA synthetase domains › Succinyl-CoA synthetase domains › Ligase_CoA_2 0.64 58.0 5.45e-01 100.0% 86.5%
4326866 2002.1.1.120 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Radical_SAM 0.64 54.0 4.28e-01 90.5% 80.4%
3171546 2002.1.1.0 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels 0.64 57.0 3.96e-01 97.1% 56.7%
3897249 2004.1.1.16 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Arf 0.64 58.0 5.33e-01 100.0% 90.3%
5059170 2004.1.1.29 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD 0.64 54.0 4.84e-01 91.2% 73.2%
10020 2007.3.1.6 ↗ a/b three-layered sandwiches › Flavodoxin-like › Succinyl-CoA synthetase domains › Succinyl-CoA synthetase domains › Ligase_CoA_2 0.64 57.0 5.45e-01 100.0% 91.4%
3568797 2004.1.1.16 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Arf 0.63 57.0 5.26e-01 100.0% 87.7%
3254911 2003.1.5.67 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_12 0.63 50.0 3.69e-01 85.4% 69.7%
3947905 2010.1.1.3 ↗ a/b three-layered sandwiches › EDD domain › EDD domain › EDD domain › EIIA-man 0.63 45.0 4.66e-01 100.0% 79.2%
3787836 2002.1.1.0 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels 0.63 56.0 3.92e-01 97.1% 57.3%
5036843 2002.1.1.120 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Radical_SAM 0.63 53.0 4.40e-01 91.2% 95.9%
4126816 7577.1.1.1 ↗ a/b three-layered sandwiches › PLP-dependent transferases › PLP-dependent transferases › PLP-dependent transferases › Aminotran_1_2 0.63 57.0 3.56e-01 100.0% 21.5%
4933451 2007.3.1.6 ↗ a/b three-layered sandwiches › Flavodoxin-like › Succinyl-CoA synthetase domains › Succinyl-CoA synthetase domains › Ligase_CoA_2 0.62 56.0 5.26e-01 100.0% 86.5%
4164634 2007.2.1.1 ↗ a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › Flavoproteins › Flavodoxin_1 0.62 56.0 5.27e-01 100.0% 86.7%
4967686 2008.1.1.108 ↗ a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › DUF234 0.62 50.0 5.08e-01 92.0% 87.4%
3385512 2005.1.1.11 ↗ a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › ATP_bind_3 0.62 44.0 3.63e-01 73.0% 49.0%
3965602 2002.1.1.120 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Radical_SAM 0.62 57.0 4.36e-01 100.0% 82.0%
4051683 2007.2.1.1 ↗ a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › Flavoproteins › Flavodoxin_1 0.61 55.0 5.30e-01 100.0% 89.4%
4126648 2003.1.1.120 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › NAD-bd_HRPKS_sdrA 0.61 55.0 5.00e-01 100.0% 73.0%
4490101 2002.1.1.0 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels 0.61 56.0 4.35e-01 100.0% 83.4%
10000 2007.2.1.1 ↗ a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › Flavoproteins › Flavodoxin_1 0.61 55.0 5.36e-01 100.0% 93.4%
5075252 2007.2.1.14 ↗ a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › Flavoproteins › Flavodoxin_3 0.61 55.0 5.37e-01 100.0% 98.7%
3516224 7512.1.1.53 ↗ a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › ALG11_N 0.61 56.0 4.44e-01 100.0% 88.3%
4214280 2007.2.1.1 ↗ a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › Flavoproteins › Flavodoxin_1 0.61 55.0 5.41e-01 100.0% 94.0%
1870502 2002.1.1.55 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Glyco_hydro_25 0.61 51.0 4.43e-01 93.4% 93.8%
5001244 2007.2.1.1 ↗ a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › Flavoproteins › Flavodoxin_1 0.61 55.0 5.41e-01 100.0% 97.2%
4967153 2007.2.1.1 ↗ a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › Flavoproteins › Flavodoxin_1 0.60 54.0 5.32e-01 100.0% 94.7%
3190760 2002.1.1.0 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels 0.60 55.0 3.89e-01 100.0% 92.0%
5063558 2002.1.1.120 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Radical_SAM 0.60 55.0 4.17e-01 100.0% 76.9%
5055151 2007.2.1.1 ↗ a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › Flavoproteins › Flavodoxin_1 0.60 54.0 5.34e-01 100.0% 98.6%
5052299 2002.1.1.120 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Radical_SAM 0.60 55.0 4.00e-01 100.0% 66.8%
3599996 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.60 50.0 4.53e-01 91.2% 84.0%
5060442 2007.2.1.1 ↗ a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › Flavoproteins › Flavodoxin_1 0.59 53.0 5.25e-01 100.0% 97.9%
4027992 2004.1.1.159 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Mur_ligase_M 0.59 54.0 4.36e-01 100.0% 77.7%
4975792 2007.2.1.1 ↗ a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › Flavoproteins › Flavodoxin_1 0.59 53.0 5.22e-01 100.0% 95.3%
3952556 2002.1.1.16 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Bac_luciferase 0.59 51.0 4.13e-01 94.2% 85.2%
3587896 2002.1.1.120 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Radical_SAM 0.59 53.0 4.14e-01 100.0% 82.3%
3957976 2002.1.1.120 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Radical_SAM 0.59 52.0 4.68e-01 95.6% 86.5%
4973382 2007.2.1.1 ↗ a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › Flavoproteins › Flavodoxin_1 0.58 53.0 5.29e-01 100.0% 99.3%
3272325 2003.1.5.67 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_12 0.58 52.0 4.27e-01 98.5% 73.6%
3429317 2004.1.1.56 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › NB-ARC 0.58 48.0 3.98e-01 91.2% 78.4%
3683378 2004.1.1.56 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › NB-ARC 0.57 44.0 4.34e-01 82.5% 82.0%
3661457 2004.1.1.29 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD 0.57 49.0 3.29e-01 94.2% 68.2%
4584853 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.57 47.0 4.73e-01 100.0% 90.4%
3825901 2006.1.4.3 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › NYN 0.57 49.0 4.73e-01 94.2% 98.1%
3837967 2004.1.1.138 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DNA_pol3_delta 0.56 46.0 4.51e-01 87.6% 91.3%
3230043 207.1.1.0 ↗ beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats 0.55 49.0 3.83e-01 97.8% 85.9%
5049858 7512.1.1.3 ↗ a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glycos_transf_1 0.53 47.0 3.64e-01 100.0% 45.8%
D2 high residues 54-121
PDB
Domain cluster: representative
CATH (27)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4dq2A03 2.30.30.100 Mainly Beta › Roll › SH3 type barrels. › 0.64 38.0 4.45e-01 76.5% 87.2%
1eqtA00 2.40.50.40 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › 0.63 38.0 3.89e-01 75.0% 61.2%
1rl2A01 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.63 40.0 4.34e-01 83.8% 78.6%
4bpnW02 2.40.50.740 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Ribosomal protein S4, central domain 0.62 40.0 4.49e-01 92.6% 88.2%
1f9qD00 2.40.50.40 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › 0.61 39.0 3.99e-01 75.0% 66.7%
1icwB00 2.40.50.40 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › 0.60 40.0 4.05e-01 76.5% 71.2%
4ntqA00 3.10.380.20 Alpha Beta › Roll › Ribonuclease domain of colicin e3 (Residues 456-551) › Novel toxin 21 (CdiA), C-terminal domain 0.60 35.0 3.46e-01 92.6% 51.3%
1nr4C00 2.40.50.40 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › 0.59 38.0 3.90e-01 76.5% 68.2%
2eyqA05 2.40.10.170 Mainly Beta › Beta Barrel › Thrombin, subunit H › 0.58 40.0 4.24e-01 76.5% 83.1%
1z47A03 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.58 40.0 4.53e-01 89.7% 100.0%
2fhdA01 2.30.30.140 Mainly Beta › Roll › SH3 type barrels. › 0.58 41.0 4.32e-01 76.5% 82.3%
2v1rA00 2.30.30.40 Mainly Beta › Roll › SH3 type barrels. › SH3 Domains 0.58 34.0 3.50e-01 75.0% 58.2%
3kbgA02 2.40.50.740 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Ribosomal protein S4, central domain 0.57 39.0 4.31e-01 97.1% 92.5%
1eotA00 2.40.50.40 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › 0.57 37.0 3.62e-01 75.0% 60.8%
4q66D01 6.20.120.50 Special › Other non-globular › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › 0.57 37.0 3.66e-01 91.2% 61.6%
2ky8A00 3.30.890.10 Alpha Beta › 2-Layer Sandwich › Methyl-cpg-binding Protein 2; Chain A › Methyl-cpg-binding Protein 2; Chain A 0.56 41.0 4.11e-01 79.4% 85.7%
3sszA01 3.30.390.10 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain 0.55 47.0 3.83e-01 98.5% 89.5%
6eugA00 2.115.10.20 Mainly Beta › 5 Propeller › Tachylectin-2; Chain A › Glycosyl hydrolase domain; family 43 0.54 43.0 2.76e-01 98.5% 17.3%
2wweA01 3.30.1520.10 Alpha Beta › 2-Layer Sandwich › PX Domain › Phox-like domain 0.54 44.0 3.89e-01 92.6% 99.0%
6cmzA02 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.54 38.0 3.17e-01 75.0% 54.6%
1x6oA02 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.53 43.0 4.11e-01 89.7% 84.8%
2a9sB00 3.90.950.20 Alpha Beta › Alpha-Beta Complex › Maf protein › CinA-like 0.52 44.0 3.44e-01 100.0% 75.8%
1sulB00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.52 42.0 3.09e-01 91.2% 38.5%
1z6nA00 3.40.30.10 Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin 0.52 43.0 3.40e-01 100.0% 52.4%
4bzyA02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.52 35.0 3.00e-01 70.6% 61.1%
2k18A02 3.40.30.10 Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin 0.51 42.0 3.52e-01 95.6% 83.7%
3agkA01 3.30.960.10 Alpha Beta › 2-Layer Sandwich › Translation, Eukaryotic Peptide Chain Release Factor Subunit 1; Chain A › eRF1 domain 1 0.50 37.0 3.14e-01 82.4% 85.2%
ECOD (42)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3933293 4.8.1.0 ↗ beta barrels › SH3 › Chromo domain-like › Chromo domain-like 0.68 41.0 4.40e-01 79.4% 70.7%
5017964 220.1.1.322 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like › DUF6141 0.64 46.0 4.23e-01 76.5% 68.5%
5068388 2.4.1.0 ↗ beta barrels › OB-fold › MOP-like › MOP-like 0.64 45.0 4.84e-01 92.6% 90.9%
3912274 1170.1.1.1 ↗ beta barrels › IL8-related › IL8-related › IL8 › IL8 0.63 38.0 3.79e-01 75.0% 58.6%
3911547 1170.1.1.1 ↗ beta barrels › IL8-related › IL8-related › IL8 › IL8 0.62 40.0 3.69e-01 75.0% 52.9%
4018760 4.8.1.0 ↗ beta barrels › SH3 › Chromo domain-like › Chromo domain-like 0.60 43.0 4.16e-01 75.0% 74.7%
4424678 1170.1.1.1 ↗ beta barrels › IL8-related › IL8-related › IL8 › IL8 0.60 39.0 4.04e-01 75.0% 70.8%
4623301 220.1.1.0 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like 0.59 42.0 3.81e-01 75.0% 81.1%
3706670 292.2.1.6 ↗ a+b two layers › RIP/Polo-box domain › Polo-box domain › Polo-box domain › DUF4520 0.58 36.0 3.14e-01 88.2% 39.1%
3927411 4.8.1.0 ↗ beta barrels › SH3 › Chromo domain-like › Chromo domain-like 0.58 35.0 4.04e-01 82.4% 91.1%
3738846 633.23.1.12 ↗ alpha bundles › Bromodomain-like › Claudin › Claudin › Fig1 0.57 34.0 2.46e-01 83.8% 20.0%
4353121 218.1.1.8 ↗ a+b two layers › Enolase-N/ribosomal protein › Enolase N-terminal domain-like › Enolase N-terminal domain-like › HrcA 0.57 47.0 4.22e-01 94.1% 99.0%
4025365 220.1.1.74 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like › PIG-H 0.57 40.0 3.46e-01 75.0% 50.9%
3313313 2.1.1.0 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.57 40.0 3.43e-01 73.5% 50.0%
3690017 4.1.1.72 ↗ beta barrels › SH3 › SH3 › SH3 › Hva1_TUDOR 0.56 38.0 3.42e-01 73.5% 51.1%
3960054 2003.1.2.58 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain › Pyr_redox, Pyr_redox_2 0.56 39.0 2.71e-01 73.5% 52.7%
4286279 206.1.3.55 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › TTL, ATPgrasp_YheCD 0.55 40.0 2.58e-01 79.4% 38.7%
4373795 220.1.1.126 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like › Ycf4 0.55 39.0 3.35e-01 76.5% 71.2%
4278807 218.1.1.8 ↗ a+b two layers › Enolase-N/ribosomal protein › Enolase N-terminal domain-like › Enolase N-terminal domain-like › HrcA 0.55 49.0 4.18e-01 100.0% 95.5%
4011051 2003.1.2.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain 0.55 41.0 3.07e-01 79.4% 44.4%
3660358 4.1.1.0 ↗ beta barrels › SH3 › SH3 › SH3 0.54 36.0 3.80e-01 75.0% 78.3%
1877618 330.15.1.1 ↗ a+b two layers › dsRBD-like › VtrA protein periplasmic domain › VtrA protein periplasmic domain › VtrA_C 0.54 39.0 3.56e-01 91.2% 57.8%
3307236 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.54 41.0 3.45e-01 83.8% 50.8%
None — 0.54 39.0 2.72e-01 79.4% 57.3%
3717380 2.1.1.13 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › eIF-5a 0.54 43.0 4.14e-01 89.7% 85.0%
3646092 719.2.1.1 ↗ beta barrels › XRCC4, N-terminal domain-like › NE0471 N-terminal domain-like › NE0471 N-terminal domain-like › GBBH-like_N 0.53 44.0 3.64e-01 97.1% 84.4%
3594065 2.1.1.0 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.53 44.0 3.55e-01 94.1% 50.7%
3931076 214.1.1.0 ↗ a+b two layers › SH2 › SH2 › SH2 0.53 42.0 3.55e-01 89.7% 63.3%
5059830 4.7.1.0 ↗ beta barrels › SH3 › RNase P subunit p29 › RNase P subunit p29 0.52 38.0 3.46e-01 76.5% 68.9%
3548072 2.1.1.70 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › Prot_ATP_ID_OB_C 0.52 44.0 3.43e-01 94.1% 46.7%
4280539 109.21.1.8 ↗ alpha superhelices › Repetitive alpha hairpins › Nucleoporin NUP85/Nucleoporin NUP145 C-terminal domain › Nucleoporin NUP85/Nucleoporin NUP145 C-terminal domain › WD40 0.52 39.0 2.24e-01 82.4% 45.1%
4014598 2003.1.2.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain 0.52 38.0 2.65e-01 77.9% 91.4%
3484771 375.5.1.1 ↗ few secondary structure elements › Rubredoxin-like › NOB1 zinc finger-like › NOB1 zinc finger-like › NOB1_Zn_bind 0.52 36.0 3.81e-01 82.4% 85.0%
3599920 2.1.1.0 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.51 39.0 3.66e-01 83.8% 81.2%
5017867 2484.1.1.66 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_3 0.51 43.0 3.28e-01 95.6% 45.0%
3962625 1.1.5.33 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Trypsin_2 0.51 35.0 3.21e-01 70.6% 92.2%
4988423 4210.1.1.0 ↗ a+b two layers › WGR domain › WGR domain › WGR domain 0.51 38.0 3.68e-01 83.8% 68.8%
4484723 220.1.1.126 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like › Ycf4 0.51 36.0 3.21e-01 76.5% 53.8%
3514049 5.1.4.1 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › WD40 0.51 42.0 2.82e-01 98.5% 61.8%
3174848 220.1.1.36 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like › PH_12 0.51 40.0 2.93e-01 89.7% 32.6%
3901539 209.1.1.1 ↗ a+b complex topology › C-type lectin-like › C-type lectin-like › C-type lectin-like › Lectin_C 0.51 36.0 2.84e-01 75.0% 43.4%
4254867 375.1.4.1 ↗ few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Aspartate carbamoyltransferase, Regulatory-chain, C-terminal domain › PyrI_C 0.50 32.0 3.52e-01 83.8% 81.8%