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putative_polynucleotide_kinase

Euk-Vir

Pithovirus_sibericum

putative_polynucleotide_kinase__YP_009001177__Pithovirus_sibericum__1450746

Identity

Accession:
YP_009001177 ↗
Protein ID:
putative_polynucleotide_kinase
Kingdom:
euk

Quality

84.2 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 14-85
PDB
Domain cluster: representative
CATH (41)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2m3xC02 2.40.10.360 Mainly Beta › Beta Barrel › Thrombin, subunit H › 0.66 40.0 4.14e-01 88.9% 63.8%
1ksiA01 3.10.450.40 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.64 52.0 4.73e-01 87.5% 84.4%
1ksiA02 3.10.450.40 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.64 53.0 4.86e-01 91.7% 94.8%
5xu6C01 3.30.200.110 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Inositol-pentakisphosphate 2-kinase, N-lobe 0.63 44.0 3.88e-01 73.6% 88.9%
3loyA01 3.10.450.40 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.63 52.0 4.65e-01 91.7% 85.1%
2vb6A01 2.30.30.360 Mainly Beta › Roll › SH3 type barrels. › Myosin S1 fragment, N-terminal 0.61 35.0 3.96e-01 72.2% 75.9%
2e8yA04 2.60.40.1180 Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II 0.61 43.0 3.99e-01 73.6% 100.0%
3ovcA01 3.30.200.150 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › 0.60 47.0 4.74e-01 83.3% 91.5%
4hgzA02 2.20.25.570 Mainly Beta › Single Sheet › N-terminal domain of TfIIb › 0.60 39.0 4.22e-01 70.8% 80.0%
3al9A01 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.60 50.0 3.12e-01 97.2% 55.6%
4m4zA01 2.30.30.40 Mainly Beta › Roll › SH3 type barrels. › SH3 Domains 0.60 36.0 4.22e-01 73.6% 93.6%
4huzA02 3.10.180.10 Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 0.59 38.0 2.99e-01 76.4% 31.1%
3m2oA01 3.30.720.120 Alpha Beta › 2-Layer Sandwich › Signal recognition particle alu RNA binding heterodimer, srp9/1 › 0.59 34.0 3.81e-01 73.6% 75.5%
1zu0A01 3.40.190.10 Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II 0.59 47.0 3.57e-01 88.9% 85.2%
2xu8A00 3.90.70.190 Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › Domain of unknown function (DUF5086) 0.58 40.0 3.42e-01 70.8% 47.4%
3lzhA01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.58 44.0 4.11e-01 81.9% 100.0%
4i8oA02 3.30.160.690 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Bacterial toxin RNase RnlA/LsoA, N repeated domain 0.58 44.0 4.18e-01 88.9% 67.8%
2r55A00 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.58 45.0 3.42e-01 91.7% 54.8%
3havA01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.57 46.0 4.28e-01 87.5% 96.6%
2ymsA00 2.40.128.630 Mainly Beta › Beta Barrel › Lipocalin › 0.57 46.0 3.85e-01 88.9% 57.3%
5upiA01 2.70.98.30 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › Golgi alpha-mannosidase II; domain 4 0.57 46.0 3.45e-01 90.3% 58.5%
2ffsA00 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.57 44.0 3.57e-01 90.3% 42.8%
3tfzB00 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.56 48.0 3.76e-01 98.6% 61.2%
3u97A00 3.10.450.530 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › Ribonuclease toxin, BrnT, of type II toxin-antitoxin system 0.56 44.0 4.38e-01 86.1% 100.0%
3hwcA02 2.40.110.10 Mainly Beta › Beta Barrel › Butyryl-CoA Dehydrogenase, subunit A; domain 2 › Butyryl-CoA Dehydrogenase, subunit A, domain 2 0.56 42.0 3.55e-01 80.6% 80.8%
6ctzA01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.55 42.0 3.94e-01 83.3% 96.8%
3qszA00 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.55 45.0 3.40e-01 90.3% 63.3%
5swiD01 2.70.98.10 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › 0.55 44.0 3.11e-01 90.3% 46.7%
3m07A04 2.60.40.1180 Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II 0.55 38.0 3.93e-01 73.6% 100.0%
2e3nA00 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.54 44.0 3.17e-01 91.7% 54.5%
5iqaA01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.54 42.0 3.99e-01 86.1% 98.9%
2arzA02 3.20.180.10 Alpha Beta › Alpha-Beta Barrel › Split barrel-like › PNP-oxidase-like 0.54 39.0 3.66e-01 76.4% 73.9%
6serA01 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.54 43.0 3.15e-01 93.1% 50.4%
1jssA00 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.53 42.0 3.19e-01 90.3% 57.8%
2mouA00 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.53 42.0 3.15e-01 93.1% 54.1%
1ul7A00 3.30.310.80 Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › Kinase associated domain 1, KA1 0.53 42.0 3.76e-01 87.5% 61.8%
1kyfA01 2.60.40.1230 Mainly Beta › Sandwich › Immunoglobulin-like › Gamma-adaptin ear (GAE) domain 0.52 36.0 3.04e-01 73.6% 61.9%
6l6jA02 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.52 36.0 2.96e-01 73.6% 76.5%
1vr5A01 3.40.190.10 Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II 0.51 40.0 3.19e-01 83.3% 91.8%
3o9zD02 3.30.360.10 Alpha Beta › 2-Layer Sandwich › Dihydrodipicolinate Reductase; domain 2 › Dihydrodipicolinate Reductase; domain 2 0.51 40.0 3.10e-01 88.9% 42.5%
1s2oA02 3.90.1070.10 Alpha Beta › Alpha-Beta Complex › Hypothetical Protein Ta0175; Chain: A, domain 2 › 0.50 36.0 3.71e-01 79.2% 95.8%
ECOD (44)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3463667 5.1.3.144 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › b-prop_At3g26010-like 0.69 52.0 3.42e-01 90.3% 18.2%
3773898 103.4.1.0 alpha arrays › RuvA-C › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein 0.66 42.0 3.80e-01 81.9% 48.4%
3247299 7089.1.1.0 a+b two layers › Methane monooxygenase hydroxylase, MmoD › Methane monooxygenase hydroxylase, MmoD › Methane monooxygenase hydroxylase, MmoD 0.66 47.0 3.98e-01 75.0% 59.2%
5074928 331.1.1.0 a+b two layers › TBP-like › TATA-box binding protein-like › TATA-box binding protein-like 0.65 41.0 4.34e-01 87.5% 72.3%
4953306 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.64 47.0 3.28e-01 80.6% 85.4%
3460209 5.1.3.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed 0.61 50.0 3.20e-01 91.7% 19.4%
3973605 243.3.1.0 a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin 0.61 49.0 5.04e-01 90.3% 100.0%
3717592 5.1.3.116 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › Kelch_KLHDC2_KLHL20_DRC7 0.59 48.0 2.98e-01 88.9% 22.1%
3468705 5.1.3.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed 0.59 48.0 3.04e-01 88.9% 16.7%
3893410 5.1.3.135 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › Kelch_1, Kelch_KLHDC2_KLHL20_DRC7, Beta-prop_ATRN-LZTR1 0.59 46.0 2.97e-01 84.7% 25.8%
3878946 389.1.2.0 few secondary structure elements › EGF-like › EGF-related › Complement control module/SCR domain 0.59 39.0 4.45e-01 86.1% 98.0%
4033832 3425.2.1.2 a+b three layers › Two-component system yycF/yycG regulatory protein yycH-like › YycH C-terminal domain › YycH C-terminal domain › YycI 0.59 50.0 3.59e-01 95.8% 32.0%
4033616 7523.1.1.3 a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II › SBP_bac_5 0.59 44.0 3.31e-01 81.9% 57.4%
3807987 5.1.3.6 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › Kelch_1 0.59 47.0 3.16e-01 91.7% 35.6%
3464481 5.1.3.142 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › Beta-prop_AT5G49610-like 0.59 46.0 2.93e-01 86.1% 21.9%
3829694 5.1.3.67 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › FBA_1 0.58 47.0 3.11e-01 91.7% 35.2%
5075779 331.4.1.0 a+b two layers › TBP-like › Kinase associated domain 1, KA1 › Kinase associated domain 1, KA1 0.57 47.0 4.62e-01 93.1% 87.5%
3711120 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.57 40.0 3.24e-01 73.6% 57.1%
3196889 206.1.1.11 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › APH 0.57 45.0 2.76e-01 86.1% 27.7%
2755883 331.19.1.1 a+b two layers › TBP-like › Toxin RnlA N-terminal domains › Toxin RnlA N-terminal domains › RnlA_toxin 0.57 44.0 4.14e-01 90.3% 67.4%
1229147 206.1.1.11 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › APH 0.57 44.0 2.94e-01 84.7% 30.1%
3164889 7523.1.1.0 a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II 0.56 44.0 3.59e-01 86.1% 86.1%
3687983 216.1.1.0 a+b two layers › UBC-like › UBC-like › UBC-like 0.56 46.0 3.74e-01 91.7% 47.9%
3270571 11.1.1.44 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Alpha_adaptinC2 0.56 39.0 3.29e-01 73.6% 63.2%
3964888 10.12.1.0 beta sandwiches › jelly-roll › Double-stranded beta-helix › Double-stranded beta-helix 0.56 41.0 3.01e-01 91.7% 27.1%
5024609 7523.1.1.3 a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II › SBP_bac_5 0.55 44.0 3.36e-01 88.9% 80.9%
3703190 7.1.1.15 beta barrels › PDZ domain › PDZ domain › PDZ domain › DUF7759 0.55 38.0 3.42e-01 72.2% 90.3%
3601211 331.3.1.0 a+b two layers › TBP-like › Bet v1-like › Bet v1-like 0.55 45.0 3.11e-01 90.3% 46.0%
3653780 10.12.1.3 beta sandwiches › jelly-roll › Double-stranded beta-helix › Double-stranded beta-helix › Cupin_1 0.54 39.0 2.88e-01 77.8% 56.2%
3584246 708.1.1.16 beta complex topology › ETN0001 domain-like › ETN0001 domain-like › NAC/WRKY/GCM/WOPR domain › RYYR-CCHC 0.54 44.0 3.93e-01 90.3% 72.1%
3595065 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.54 37.0 3.10e-01 73.6% 57.9%
1839315 206.1.1.11 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › APH 0.54 43.0 2.89e-01 88.9% 28.8%
3916252 216.1.1.0 a+b two layers › UBC-like › UBC-like › UBC-like 0.54 44.0 3.95e-01 93.1% 93.3%
4931123 330.4.1.1 a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC 0.53 42.0 4.23e-01 91.7% 97.3%
4949872 241.1.1.0 a+b two layers › Type III secretory system chaperone-like › Type III secretory system chaperone › Type III secretory system chaperone 0.53 43.0 3.62e-01 91.7% 94.6%
3498699 2004.1.1.19 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Ras 0.53 44.0 3.34e-01 98.6% 86.2%
3930230 331.4.1.5 a+b two layers › TBP-like › Kinase associated domain 1, KA1 › Kinase associated domain 1, KA1 › KA1_BRSK 0.53 42.0 3.63e-01 88.9% 63.5%
3198655 211.1.1.0 a+b two layers › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase 0.52 34.0 3.62e-01 76.4% 75.4%
4042443 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.52 35.0 3.30e-01 70.8% 55.8%
3735914 331.3.1.2 a+b two layers › TBP-like › Bet v1-like › Bet v1-like › Ring_hydroxyl_A 0.51 39.0 2.91e-01 86.1% 31.8%
3268245 4099.1.1.0 a+b two layers › Kinetochore globular domain-like › Kinetochore globular domain-like › Kinetochore globular domain-like 0.51 41.0 3.74e-01 91.7% 97.0%
3968482 206.1.1.11 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › APH 0.51 39.0 2.70e-01 88.9% 32.8%
5076377 3016.1.1.1 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › Aminotran_1_2 0.50 36.0 3.44e-01 77.8% 81.1%
2075041 3012.1.1.3 a+b two layers › Cof C2 cap domain › Cof C2 cap domain › Cof C2 cap domain › S6PP 0.50 36.0 3.71e-01 79.2% 95.8%
D2 medium residues 86-114_247-302
PDB
Domain cluster: representative
CATH (11)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1a21A01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.59 44.0 4.27e-01 80.0% 93.9%
4r9pA00 2.60.200.10 Mainly Beta › Sandwich › Tumour Suppressor Smad4 › 0.57 42.0 3.26e-01 81.2% 85.2%
2x10A04 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.55 42.0 3.97e-01 81.2% 95.0%
2d42A02 3.10.450.380 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.53 33.0 3.57e-01 88.2% 78.5%
2rovA00 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.53 44.0 3.94e-01 89.4% 83.8%
1nbuA00 3.30.1130.10 Alpha Beta › 2-Layer Sandwich › GTP Cyclohydrolase I, domain 2 › GTP cyclohydrolase I, C-terminal domain/NADPH-dependent 7-cyano-7-deazaguanine reductase, N-terminal domain 0.52 40.0 3.64e-01 83.5% 89.8%
1v89A00 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.51 42.0 3.81e-01 89.4% 74.6%
2cg8C01 3.30.1130.10 Alpha Beta › 2-Layer Sandwich › GTP Cyclohydrolase I, domain 2 › GTP cyclohydrolase I, C-terminal domain/NADPH-dependent 7-cyano-7-deazaguanine reductase, N-terminal domain 0.51 40.0 3.61e-01 84.7% 89.9%
2o90A00 3.30.1130.10 Alpha Beta › 2-Layer Sandwich › GTP Cyclohydrolase I, domain 2 › GTP cyclohydrolase I, C-terminal domain/NADPH-dependent 7-cyano-7-deazaguanine reductase, N-terminal domain 0.51 39.0 3.56e-01 83.5% 89.6%
4ikbA00 3.30.1520.10 Alpha Beta › 2-Layer Sandwich › PX Domain › Phox-like domain 0.50 36.0 3.23e-01 76.5% 93.0%
1dhnA00 3.30.1130.10 Alpha Beta › 2-Layer Sandwich › GTP Cyclohydrolase I, domain 2 › GTP cyclohydrolase I, C-terminal domain/NADPH-dependent 7-cyano-7-deazaguanine reductase, N-terminal domain 0.50 40.0 3.57e-01 87.1% 89.3%
ECOD (18)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3245738 216.1.1.4 a+b two layers › UBC-like › UBC-like › UBC-like › RWD 0.63 35.0 3.21e-01 75.3% 41.8%
3866695 295.1.1.3 a+b two layers › ssDNA-binding transcriptional regulator domain-like › ssDNA-binding transcriptional regulator domain › ssDNA-binding transcriptional regulator domain › PurA 0.57 45.0 3.78e-01 88.2% 83.2%
4237534 330.7.1.1 a+b two layers › dsRBD-like › PI-Pfui intein middle domain › PI-Pfui intein middle domain › DUF905 0.56 32.0 3.60e-01 90.6% 75.0%
3736231 216.1.1.0 a+b two layers › UBC-like › UBC-like › UBC-like 0.55 37.0 3.32e-01 98.8% 48.0%
3782292 4.1.1.170 beta barrels › SH3 › SH3 › SH3 › Rad9_Rad53_bind 0.53 36.0 3.69e-01 81.2% 73.8%
3895887 11.1.1.96 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › C1-set 0.53 41.0 3.53e-01 83.5% 72.6%
3236056 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.52 43.0 3.90e-01 89.4% 80.9%
3719283 10.37.1.1 beta sandwiches › jelly-roll › TerD › TerD › TerD 0.52 36.0 2.80e-01 71.8% 74.7%
3629599 11.1.1.2 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › fn3 0.52 39.0 3.64e-01 80.0% 83.8%
3993341 220.1.1.1 beta barrels › PH domain-like › PH domain-like › PH domain-like › PH 0.52 36.0 3.68e-01 74.1% 77.6%
3718531 11.1.1.360 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › HYDIN_VesB_CFA65-like_Ig 0.52 38.0 2.46e-01 78.8% 24.0%
3742244 216.1.1.4 a+b two layers › UBC-like › UBC-like › UBC-like › RWD 0.52 35.0 3.17e-01 98.8% 49.2%
3195948 230.1.1.4 a+b two layers › T-fold › Tetrahydrobiopterin biosynthesis enzymes-like › Tetrahydrobiopterin biosynthesis enzymes-like › FolB 0.52 40.0 3.63e-01 83.5% 88.7%
3267306 230.1.1.4 a+b two layers › T-fold › Tetrahydrobiopterin biosynthesis enzymes-like › Tetrahydrobiopterin biosynthesis enzymes-like › FolB 0.51 40.0 3.54e-01 85.9% 84.8%
3202870 220.1.1.36 beta barrels › PH domain-like › PH domain-like › PH domain-like › PH_12 0.51 42.0 3.73e-01 89.4% 80.8%
3193761 10.13.1.1 beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A › E1-E2_ATPase 0.51 41.0 3.02e-01 87.1% 40.0%
3634550 220.1.1.0 beta barrels › PH domain-like › PH domain-like › PH domain-like 0.50 41.0 3.55e-01 89.4% 71.9%
3607981 4.1.1.0 beta barrels › SH3 › SH3 › SH3 0.50 34.0 3.60e-01 87.1% 82.4%
D3 medium residues 115-246
PDB
CATH (18)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1auvA03 3.30.470.20 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › ATP-grasp fold, B domain 0.67 37.0 4.11e-01 72.7% 67.6%
3qwuA02 3.30.470.30 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme 0.65 51.0 4.59e-01 100.0% 60.6%
1s68A02 3.30.470.30 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme 0.65 52.0 5.60e-01 96.2% 100.0%
5dmxB02 3.30.470.20 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › ATP-grasp fold, B domain 0.62 37.0 3.56e-01 75.0% 50.0%
3vnnA00 3.30.470.30 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme 0.53 44.0 4.57e-01 100.0% 95.2%
4tm5A01 3.30.470.10 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › Aminotransferase class 4, branched-chain amino acid transferase, N-terminal domain 0.53 37.0 3.72e-01 71.2% 78.0%
4ckbA01 3.30.470.140 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › 0.52 35.0 3.18e-01 100.0% 50.0%
4u7aA00 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.52 31.0 2.32e-01 95.5% 21.1%
6rarI01 3.30.470.30 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme 0.52 46.0 4.05e-01 100.0% 65.1%
2hivA02 3.30.470.30 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme 0.52 46.0 4.00e-01 100.0% 62.6%
4dimA03 3.30.470.20 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › ATP-grasp fold, B domain 0.52 39.0 3.36e-01 79.5% 56.1%
2q7dA02 3.30.470.20 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › ATP-grasp fold, B domain 0.51 36.0 3.12e-01 72.0% 53.5%
3wnzA03 3.30.470.20 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › ATP-grasp fold, B domain 0.51 39.0 3.85e-01 80.3% 88.2%
1xk5A01 3.30.470.30 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme 0.51 41.0 3.55e-01 100.0% 56.3%
2cfmA02 3.30.470.30 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme 0.51 45.0 3.94e-01 100.0% 64.2%
1vs0A02 3.30.470.30 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme 0.51 40.0 4.29e-01 96.2% 100.0%
3l2pA03 3.30.470.30 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › DNA ligase/mRNA capping enzyme 0.50 42.0 4.43e-01 95.5% 100.0%
3votB02 3.30.470.20 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › ATP-grasp fold, B domain 0.50 38.0 2.95e-01 79.5% 41.3%
ECOD (39)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
193072 206.1.3.23 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › RNA_ligase 0.63 57.0 4.73e-01 100.0% 74.0%
3592457 206.1.3.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp 0.58 41.0 2.94e-01 72.7% 26.4%
4995719 206.1.3.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp 0.57 46.0 4.16e-01 100.0% 64.0%
3602296 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.55 51.0 4.23e-01 100.0% 64.9%
4237088 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.54 45.0 3.94e-01 100.0% 59.0%
4098851 4095.1.1.2 alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M+DNA_ligase_A_N 0.54 49.0 3.64e-01 100.0% 43.0%
3968582 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.53 46.0 4.06e-01 100.0% 64.2%
3581071 4095.1.1.2 alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M+DNA_ligase_A_N 0.53 47.0 3.29e-01 100.0% 29.9%
1837660 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.53 44.0 4.57e-01 100.0% 95.2%
3799247 206.1.3.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp 0.53 47.0 3.76e-01 100.0% 48.8%
3288874 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.53 43.0 3.80e-01 100.0% 59.0%
4666907 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.53 47.0 4.02e-01 100.0% 61.5%
3795817 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.53 47.0 3.71e-01 100.0% 47.9%
4947307 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.53 48.0 3.52e-01 100.0% 38.5%
4056196 4095.1.1.2 alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M+DNA_ligase_A_N 0.52 47.0 3.24e-01 100.0% 29.3%
4960010 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.52 46.0 3.92e-01 100.0% 59.1%
4937749 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.52 47.0 3.50e-01 100.0% 39.4%
4951306 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.52 45.0 3.15e-01 100.0% 29.6%
5036153 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.52 46.0 4.01e-01 100.0% 64.6%
4977191 206.1.3.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp 0.52 47.0 3.95e-01 100.0% 60.0%
4683228 4095.1.1.2 alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M+DNA_ligase_A_N 0.52 46.0 3.24e-01 100.0% 32.5%
4947392 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.52 45.0 3.89e-01 100.0% 60.0%
3960632 206.1.3.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp 0.52 45.0 3.89e-01 100.0% 61.0%
4631711 4095.1.1.3 alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M 0.52 45.0 3.22e-01 100.0% 32.5%
3927529 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.51 46.0 3.82e-01 100.0% 59.6%
3643093 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.51 46.0 3.78e-01 100.0% 54.9%
4935888 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.51 46.0 3.41e-01 100.0% 38.5%
5024218 206.1.3.23 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › RNA_ligase 0.51 46.0 3.50e-01 100.0% 55.9%
5031580 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.51 46.0 3.98e-01 100.0% 64.5%
4399570 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.51 46.0 3.88e-01 100.0% 58.7%
3253455 4095.1.1.2 alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M+DNA_ligase_A_N 0.51 46.0 3.20e-01 100.0% 30.7%
5042001 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.51 46.0 3.42e-01 100.0% 40.0%
4213407 4095.1.1.2 alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M+DNA_ligase_A_N 0.51 44.0 3.14e-01 100.0% 31.1%
3922871 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.51 46.0 3.82e-01 100.0% 58.3%
4153293 245.1.1.0 a+b two layers › Ribonuclease PH domain 2-like › Ribonuclease PH domain 2 › Ribonuclease PH domain 2 0.51 34.0 3.59e-01 85.6% 75.8%
4325132 4095.1.1.2 alpha bundles › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › ATP-dependent DNA ligase DNA-binding domain › DNA_ligase_A_M+DNA_ligase_A_N 0.50 46.0 3.44e-01 100.0% 40.9%
4945406 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.50 44.0 3.83e-01 100.0% 61.4%
3476026 206.1.3.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › DNA_ligase_A_M 0.50 45.0 3.60e-01 100.0% 60.7%
4966636 206.1.3.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp 0.50 46.0 3.90e-01 100.0% 62.4%
D4 medium residues 306-450
PDB
Domain cluster: representative
CATH (7)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4wqoD00 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.58 35.0 3.64e-01 82.1% 61.7%
2wzkA03 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.57 33.0 3.67e-01 82.8% 72.7%
1mijA00 1.10.10.500 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeo-prospero domain 0.55 44.0 4.48e-01 86.2% 87.8%
1sumB01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.53 28.0 3.26e-01 82.8% 68.2%
4gc0A01 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.52 42.0 3.52e-01 86.2% 81.9%
1sqgA01 1.10.940.10 Mainly Alpha › Orthogonal Bundle › N-utilizing Substance Protein B Homolog; Chain A › NusB-like 0.51 41.0 4.20e-01 98.6% 88.7%
3kh1A00 1.10.3210.10 Mainly Alpha › Orthogonal Bundle › Hypothetical protein af1432 › Hypothetical protein af1432 0.50 37.0 3.37e-01 96.6% 55.9%
ECOD (5)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3871969 5054.1.1.69 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Serinc 0.59 46.0 4.17e-01 80.7% 63.7%
3702110 593.1.1.0 alpha bundles › GroEL equatorial domain-like › GroEL equatorial domain-like › GroEL equatorial domain-like 0.56 48.0 4.05e-01 95.2% 98.1%
3832127 3615.1.1.0 alpha bundles › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain 0.53 27.0 2.94e-01 92.4% 55.2%
5060287 5051.1.1.3 alpha complex topology › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › SSF 0.53 46.0 3.22e-01 95.9% 86.9%
3666433 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.52 38.0 4.07e-01 89.7% 88.0%