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putative_tyrosine_protein_kinase

Euk-Vir

Anopheles_minimus_iridovirus

putative_tyrosine_protein_kinase__YP_009021118__Anopheles_minimus_iridovirus__1465751

Identity

Accession:
YP_009021118 ↗
Protein ID:
putative_tyrosine_protein_kinase
Kingdom:
euk

Quality

74.0 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 49-60_75-133_197-302
PDB
D2 high residues 316-479
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF05686.19 best Glyco_transf_90 72.8 3.70e-20 100.0% 34.3%
D3 medium residues 507-634_647-658
PDB
CATH (22)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3d7tA01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.80 47.0 6.07e-01 91.4% 100.0%
3jr1A01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.78 48.0 5.59e-01 70.7% 85.9%
2w4oA01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.78 43.0 5.77e-01 95.7% 100.0%
4c0tA01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.77 49.0 5.97e-01 85.7% 96.7%
4fr4D01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.77 49.0 5.10e-01 86.4% 69.8%
5cenA01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.76 42.0 5.50e-01 92.1% 97.4%
4ks7A01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.76 50.0 5.92e-01 96.4% 95.9%
4fg9A01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.75 43.0 5.60e-01 91.4% 100.0%
3fxzA01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.75 51.0 6.01e-01 98.6% 99.0%
7zvsB01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.74 52.0 6.08e-01 97.9% 100.0%
4f0fA01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.72 47.0 5.70e-01 92.1% 98.9%
4uy9A01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.72 45.0 5.61e-01 92.9% 98.9%
2x7fC01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.72 48.0 5.73e-01 93.6% 100.0%
3mdyA01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.69 52.0 5.82e-01 83.6% 99.1%
2nryD01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.69 45.0 5.47e-01 72.9% 100.0%
4btfA03 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.65 44.0 4.91e-01 81.4% 87.5%
2pmlX01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.63 53.0 5.59e-01 99.3% 100.0%
6j5tB01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.62 47.0 5.10e-01 95.0% 93.3%
2wb8A01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.60 56.0 5.33e-01 98.6% 94.4%
3fo5B00 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.57 44.0 3.70e-01 80.7% 80.3%
2kd2A01 2.40.128.180 Mainly Beta › Beta Barrel › Lipocalin › 0.54 30.0 3.71e-01 91.4% 88.1%
1k8kD01 3.30.1460.20 Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, › 0.53 39.0 3.86e-01 80.7% 71.5%
ECOD (62)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3275851 206.1.1.20 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr 0.81 50.0 3.88e-01 91.4% 31.3%
3580183 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.79 50.0 5.07e-01 88.6% 64.3%
3599245 206.1.1.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase 0.78 52.0 3.94e-01 95.7% 30.2%
3276159 206.1.1.20 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr 0.77 49.0 3.73e-01 96.4% 29.8%
1918907 206.1.1.74 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase, PK_Tyr_Ser-Thr 0.77 52.0 4.95e-01 92.9% 60.1%
3436193 206.1.1.20 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr 0.77 51.0 3.84e-01 94.3% 30.4%
3292304 206.1.1.20 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr 0.76 50.0 3.66e-01 92.1% 27.4%
None 0.76 49.0 3.54e-01 87.1% 25.3%
3536870 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.76 49.0 3.65e-01 95.7% 27.9%
None 0.76 51.0 3.84e-01 93.6% 31.0%
None 0.76 50.0 3.39e-01 95.0% 20.4%
3276454 206.1.1.72 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase, Pkinase_fungal 0.75 48.0 3.69e-01 92.1% 30.5%
3455635 206.1.1.70 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase, ABC1 0.75 49.0 3.80e-01 96.4% 32.4%
None 0.74 50.0 3.34e-01 96.4% 19.8%
3893883 206.1.1.20 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr 0.74 52.0 3.92e-01 97.9% 31.6%
3257993 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.74 49.0 3.48e-01 87.1% 24.8%
3529333 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.74 51.0 3.77e-01 90.0% 30.0%
4013556 206.1.1.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase 0.72 47.0 3.25e-01 71.4% 20.7%
3499286 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.72 56.0 4.11e-01 80.0% 36.7%
3222951 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.72 55.0 3.93e-01 83.6% 29.3%
3840200 206.1.1.20 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr 0.71 55.0 4.07e-01 99.3% 33.6%
3202122 206.1.1.11 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › APH 0.71 47.0 3.13e-01 70.0% 17.7%
3647050 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.71 47.0 3.64e-01 91.4% 32.6%
4317590 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.71 49.0 3.68e-01 73.6% 30.5%
3253861 206.1.1.20 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr 0.71 49.0 3.73e-01 99.3% 31.4%
3275778 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.70 47.0 3.46e-01 86.4% 27.5%
3593954 206.1.1.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase 0.70 51.0 3.91e-01 96.4% 33.9%
3647739 206.1.1.20 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr 0.70 55.0 4.13e-01 97.1% 35.6%
3531320 206.1.1.4 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase,TGF_beta_GS 0.70 55.0 3.95e-01 87.1% 30.7%
4025992 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.69 47.0 3.81e-01 98.6% 38.4%
3907133 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.69 48.0 3.74e-01 95.7% 34.6%
3275633 206.1.1.20 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr 0.68 51.0 3.80e-01 90.7% 33.7%
3558331 611.7.1.0 alpha bundles › N-cbl like › Mixed lineage kinase domain-like (MLKL) N-terminal domain › Mixed lineage kinase domain-like (MLKL) N-terminal domain 0.66 49.0 3.32e-01 80.0% 22.6%
3457086 206.1.1.20 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr 0.66 45.0 3.55e-01 77.1% 34.0%
3751444 206.1.1.20 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr 0.66 47.0 3.66e-01 81.4% 34.7%
3925788 206.1.1.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase 0.65 47.0 3.57e-01 75.7% 33.4%
3222568 206.1.1.28 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Haspin_kinase 0.65 53.0 4.20e-01 100.0% 44.4%
None 0.65 46.0 3.17e-01 81.4% 21.7%
3237472 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.64 46.0 3.35e-01 99.3% 29.6%
3768647 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.64 47.0 3.55e-01 77.9% 31.9%
3966655 206.1.1.17 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Kdo 0.64 51.0 4.07e-01 93.6% 44.2%
3501996 206.1.1.51 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PIP49_C 0.63 60.0 4.46e-01 100.0% 45.9%
3417528 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.63 49.0 3.62e-01 89.3% 35.0%
166770 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.63 51.0 3.80e-01 96.4% 35.8%
5079337 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.63 47.0 3.54e-01 89.3% 33.2%
3981109 206.1.1.97 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › ABC1, WaaY 0.62 52.0 4.38e-01 92.1% 53.9%
3989328 243.1.1.0 a+b two layers › Cystatin-like › NTF2-like › NTF2-like 0.62 33.0 3.97e-01 97.1% 77.7%
3605323 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.61 50.0 3.42e-01 92.1% 26.7%
3616471 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.61 47.0 3.49e-01 97.1% 34.7%
4011470 206.1.1.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase 0.60 54.0 3.93e-01 97.1% 38.5%
3412664 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.59 48.0 3.39e-01 85.0% 34.0%
3216358 206.1.1.10 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Choline_kinase 0.59 43.0 3.22e-01 92.9% 31.6%
4435338 206.1.1.20 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr 0.58 52.0 3.82e-01 96.4% 48.1%
3367922 304.8.1.45 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › bHLH-TF_ACT-like_plant 0.57 33.0 3.83e-01 80.7% 81.1%
3507452 206.1.2.4 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › SAICAR synthase › Ins_P5_2-kin 0.57 45.0 3.18e-01 92.1% 28.4%
3367441 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.56 32.0 3.65e-01 80.7% 76.8%
3420734 331.3.1.3 a+b two layers › TBP-like › Bet v1-like › Bet v1-like › START 0.54 45.0 3.80e-01 88.6% 90.2%
3668463 331.3.1.0 a+b two layers › TBP-like › Bet v1-like › Bet v1-like 0.54 45.0 3.72e-01 88.6% 85.8%
4228206 708.1.1.0 beta complex topology › ETN0001 domain-like › ETN0001 domain-like › NAC/WRKY/GCM/WOPR domain 0.53 30.0 4.03e-01 73.6% 100.0%
3854043 331.3.1.3 a+b two layers › TBP-like › Bet v1-like › Bet v1-like › START 0.53 44.0 3.83e-01 88.6% 80.9%
3928940 241.6.1.1 a+b two layers › Type III secretory system chaperone-like › Arp2/3 complex subunits › Arp2/3 complex subunits › P34-Arc 0.53 40.0 3.81e-01 80.7% 67.3%
3727965 4955.1.1.8 a+b two layers › permuted ferredoxin-like domain in yeast RNA-polymerase beta-prime subunit › permuted ferredoxin-like domain in yeast RNA-polymerase beta-prime subunit › permuted ferredoxin-like domain in yeast RNA-polymerase beta-prime subunit › AtuA_ferredoxin 0.52 36.0 2.91e-01 70.0% 54.5%
D4 medium residues 659-755
PDB
CATH (34)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4qtcA02 1.10.510.10 Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 0.89 85.0 6.56e-01 100.0% 66.0%
1yhvA02 1.10.510.10 Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 0.80 60.0 4.62e-01 100.0% 38.5%
1phkA02 1.10.510.10 Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 0.79 59.0 4.66e-01 100.0% 40.3%
6fdyU02 1.10.510.10 Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 0.78 59.0 4.68e-01 100.0% 42.0%
4y85A02 1.10.510.10 Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 0.78 56.0 4.51e-01 99.0% 40.8%
4fr4A02 1.10.510.10 Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 0.78 57.0 4.29e-01 99.0% 34.3%
1yhsA02 1.10.510.10 Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 0.78 58.0 4.64e-01 100.0% 42.0%
5l2qB02 1.10.510.10 Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 0.77 60.0 4.69e-01 100.0% 40.9%
1gngA02 1.10.510.10 Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 0.75 58.0 4.20e-01 97.9% 31.6%
2vd5B02 1.10.510.10 Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 0.74 55.0 4.27e-01 96.9% 38.3%
3c0iA02 1.10.510.10 Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 0.73 58.0 4.45e-01 100.0% 39.0%
3gniB02 1.10.510.10 Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 0.69 54.0 4.25e-01 97.9% 40.6%
6ziwI02 1.10.510.10 Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 0.69 59.0 4.63e-01 97.9% 47.3%
3f61A02 1.10.510.10 Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 0.69 54.0 4.35e-01 100.0% 46.2%
2rioA02 1.10.510.10 Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 0.68 64.0 5.03e-01 100.0% 53.8%
3p1aA02 1.10.510.10 Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 0.68 58.0 4.73e-01 100.0% 52.1%
4c0tA02 1.10.510.10 Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 0.67 61.0 4.74e-01 96.9% 51.0%
3oz6B02 1.10.510.10 Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 0.66 60.0 4.41e-01 95.9% 98.3%
6d3kC02 1.10.510.10 Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 0.66 60.0 4.84e-01 100.0% 54.7%
4bf2A02 1.10.510.10 Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 0.66 59.0 4.76e-01 100.0% 52.8%
4uyaA02 1.10.510.10 Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 0.66 56.0 4.29e-01 99.0% 43.7%
1yvjA02 1.10.510.10 Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 0.64 61.0 4.68e-01 100.0% 50.0%
6qavC02 1.10.510.10 Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 0.64 58.0 4.61e-01 96.9% 54.9%
4krdA02 1.10.510.10 Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 0.64 57.0 4.33e-01 97.9% 44.0%
2z2wA02 1.10.510.10 Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 0.63 57.0 4.58e-01 100.0% 52.5%
1csnA02 1.10.510.10 Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 0.62 57.0 4.36e-01 100.0% 51.2%
3is5F02 1.10.510.10 Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 0.61 54.0 4.38e-01 99.0% 52.3%
1tkiA02 1.10.510.10 Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 0.61 56.0 4.16e-01 99.0% 97.9%
2bujA02 1.10.510.10 Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 0.61 57.0 4.42e-01 100.0% 56.6%
1z47A03 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.59 22.0 3.00e-01 84.5% 63.3%
2rqaA00 2.170.150.30 Mainly Beta › Beta Complex › Metal Binding Protein, Guanine Nucleotide Exchange Factor; Chain A › RIG-I-like receptor, C-terminal regulatory domain 0.55 29.0 2.63e-01 97.9% 33.6%
6m36O01 3.30.565.10 Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain 0.54 38.0 3.86e-01 86.6% 74.0%
3iuzA00 3.10.180.50 Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 0.51 40.0 2.88e-01 86.6% 73.1%
6qdws00 3.90.470.10 Alpha Beta › Alpha-Beta Complex › Ribosomal Protein L22; Chain A › Ribosomal protein L22/L17 0.50 40.0 3.91e-01 85.6% 87.2%
ECOD (49)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3247035 206.1.1.28 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Haspin_kinase 0.92 82.0 5.53e-01 93.8% 29.5%
3222568 206.1.1.28 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Haspin_kinase 0.90 78.0 5.45e-01 94.8% 32.8%
3481008 206.1.1.28 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Haspin_kinase 0.89 85.0 5.57e-01 100.0% 35.8%
3512772 206.1.1.28 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Haspin_kinase 0.89 84.0 6.04e-01 100.0% 50.6%
3926228 206.1.1.28 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Haspin_kinase 0.88 84.0 5.50e-01 100.0% 37.1%
3227376 206.1.1.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase 0.88 77.0 5.29e-01 93.8% 30.8%
3231695 206.1.1.28 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Haspin_kinase 0.88 78.0 5.33e-01 100.0% 31.0%
3791557 206.1.1.28 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Haspin_kinase 0.87 82.0 5.36e-01 100.0% 34.6%
3227288 206.1.1.28 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Haspin_kinase 0.86 77.0 6.11e-01 100.0% 50.6%
3502381 206.1.1.28 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Haspin_kinase 0.85 80.0 5.34e-01 100.0% 37.5%
3241635 206.1.1.28 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Haspin_kinase 0.84 75.0 6.15e-01 100.0% 55.8%
3242068 206.1.1.28 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Haspin_kinase 0.84 76.0 5.29e-01 100.0% 34.1%
3216195 206.1.1.28 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Haspin_kinase 0.84 76.0 5.33e-01 100.0% 34.4%
3230153 206.1.1.28 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Haspin_kinase 0.83 75.0 5.35e-01 100.0% 36.5%
3220442 206.1.1.28 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Haspin_kinase 0.82 74.0 5.77e-01 100.0% 48.9%
3959715 206.1.1.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase 0.81 56.0 3.84e-01 92.8% 22.7%
3254538 206.1.1.70 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase, ABC1 0.80 63.0 4.49e-01 100.0% 30.2%
2704750 206.1.1.70 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase, ABC1 0.79 60.0 4.08e-01 100.0% 25.0%
3931577 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.79 59.0 4.13e-01 99.0% 27.1%
3740166 206.1.1.28 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Haspin_kinase 0.79 75.0 4.89e-01 100.0% 39.7%
4100588 206.1.1.87 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase, RIO1 0.78 60.0 3.94e-01 100.0% 21.7%
3789548 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.78 59.0 4.04e-01 100.0% 24.8%
3686862 206.1.1.28 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Haspin_kinase 0.77 73.0 4.66e-01 100.0% 39.0%
3873066 206.1.1.71 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase, Kdo 0.76 59.0 3.76e-01 100.0% 18.8%
3724139 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.76 62.0 4.07e-01 100.0% 22.4%
4013490 206.1.1.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase 0.76 72.0 4.55e-01 100.0% 41.7%
3523177 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.75 64.0 4.02e-01 100.0% 20.0%
3390287 206.1.1.70 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase, ABC1 0.73 61.0 4.07e-01 100.0% 25.8%
3170528 206.1.1.28 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Haspin_kinase 0.73 70.0 4.69e-01 100.0% 35.4%
3409868 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.69 64.0 4.39e-01 100.0% 36.0%
3247540 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.69 64.0 4.39e-01 100.0% 35.3%
3930967 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.69 59.0 4.04e-01 100.0% 28.9%
3677044 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.68 62.0 4.43e-01 96.9% 51.6%
3626452 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.67 61.0 3.93e-01 96.9% 61.2%
3292935 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.67 63.0 4.39e-01 100.0% 36.8%
3629785 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.67 63.0 3.93e-01 100.0% 28.8%
3600828 206.1.1.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase 0.67 62.0 4.03e-01 97.9% 63.6%
3788607 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.66 60.0 3.89e-01 96.9% 58.2%
3223495 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.66 62.0 3.94e-01 100.0% 24.8%
4023951 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.66 62.0 4.13e-01 100.0% 28.5%
3939543 206.1.1.20 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr 0.66 60.0 4.14e-01 100.0% 32.6%
3938332 206.1.1.20 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr 0.66 61.0 4.28e-01 100.0% 35.2%
3599006 206.1.1.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase 0.65 61.0 4.16e-01 100.0% 35.9%
3593870 206.1.1.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase 0.65 61.0 3.96e-01 100.0% 27.9%
3385105 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.63 59.0 4.09e-01 100.0% 35.4%
4000743 206.1.1.78 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase, Kinase-like 0.63 59.0 4.07e-01 100.0% 33.7%
3605592 206.1.1.14 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › ABC1 0.63 58.0 3.57e-01 100.0% 34.8%
3700170 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.63 58.0 3.96e-01 100.0% 31.1%
4978550 213.1.1.1 a+b three layers › Nat/Ivy › Acyl-CoA N-acyltransferases (Nat) › Acyl-CoA N-acyltransferases (Nat) › Acetyltransf_1 0.51 45.0 3.76e-01 96.9% 95.2%
D5 medium residues 756-858
PDB
Domain cluster: representative
CATH (7)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2c5uA02 1.10.3550.20 Mainly Alpha › Orthogonal Bundle › eoxyguanosinetriphosphate triphosphohydrolase fold › 0.56 38.0 3.59e-01 71.8% 79.4%
3hl6A02 1.20.58.700 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.55 38.0 3.73e-01 87.4% 65.2%
8g4uA02 3.30.70.3290 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.54 39.0 4.19e-01 77.7% 92.9%
4hfvA01 1.20.1440.330 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.52 43.0 4.19e-01 90.3% 96.6%
3vadA01 1.20.140.20 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain 0.52 46.0 4.02e-01 98.1% 84.6%
3kp9A01 1.20.1440.130 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › VKOR domain 0.51 41.0 3.58e-01 89.3% 65.4%
7c4sB01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.51 41.0 3.06e-01 89.3% 35.5%
ECOD (9)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3959245 103.12.1.1 alpha arrays › RuvA-C › ANTAR domain › ANTAR domain › ANTAR 0.57 27.0 2.98e-01 90.3% 54.1%
3945765 2004.1.1.847 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ORC-CDC6-like 0.55 47.0 3.55e-01 100.0% 63.9%
3812751 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.53 45.0 4.11e-01 91.3% 95.6%
1578784 138.1.1.3 alpha arrays › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › DNApol3-delta_C 0.53 41.0 3.84e-01 82.5% 68.5%
3437842 148.1.3.0 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.52 30.0 3.29e-01 86.4% 69.4%
3872677 5089.1.1.12 beta complex topology › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains › Membrane attack complex/perforin (MACPF) and cholesterol-dependent cytolysin (CDC) domains › BRINP 0.51 30.0 2.95e-01 77.7% 52.2%
3575287 219.1.1.3 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › UCH 0.51 44.0 3.73e-01 98.1% 94.9%
4944142 633.11.1.4 alpha bundles › Bromodomain-like › Nqo1C-terminal domain-like › Nqo1C-terminal domain-like › Fer4_21 0.51 36.0 3.70e-01 83.5% 78.9%
3471028 101.1.4.0 alpha arrays › HTH › HTH › tetra-helical, lambda repressor-like 0.50 37.0 3.80e-01 87.4% 82.0%
D6 medium residues 859-962
PDB
D7 medium residues 963-1062
PDB