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regulatory_protein_ICP22
Euk-VirHuman_alphaherpesvirus_3
regulatory_protein_ICP22__NP_040192__Human_alphaherpesvirus_3__10335
Identity
- Accession:
- NP_040192 ↗
- Protein ID:
- regulatory_protein_ICP22
- Kingdom:
- euk
Quality
58.5
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Varicellovirus›
Human_alphaherpesvirus_3
TaxID: 10335
Cluster
View cluster (4 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 57-131
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF02479.22 best | Herpes_IE68 | 116.9 | 7.40e-34 | 100.0% | 55.2% |
CATH (2)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1ic8A01 | 1.10.260.40 | Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains | 0.57 | 41.0 | 3.86e-01 | 77.3% | 70.2% |
| 4nv0A02 | 1.10.150.340 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Pyrimidine 5'-nucleotidase (UMPH-1), N-terminal domain | 0.56 | 39.0 | 3.84e-01 | 73.3% | 68.3% |
ECOD (6)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3474973 | 397.7.1.0 ↗ | few secondary structure elements › Toxic hairpin › Ribosome-inactivating protein luffin P1 › Ribosome-inactivating protein luffin P1 | 0.69 | 44.0 | 4.96e-01 | 92.0% | 87.3% |
| 5021892 | 3896.1.1.0 ↗ | alpha duplicates or obligate multimers › Intramembrane CDP-DAG synthetase-related › Intramembrane CDP-DAG synthetase-related › Intramembrane CDP-DAG synthetase | 0.67 | 53.0 | 3.89e-01 | 86.7% | 55.0% |
| 3969653 | 142.1.1.3 ↗ | alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › Sigma70_r2 | 0.55 | 39.0 | 3.86e-01 | 74.7% | 72.5% |
| 3917203 | 2003.1.5.14 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_3 | 0.55 | 42.0 | 2.88e-01 | 82.7% | 92.2% |
| 4108644 | 603.1.1.215 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF27853 | 0.52 | 37.0 | 3.25e-01 | 96.0% | 50.9% |
| 3608273 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.50 | 36.0 | 3.30e-01 | 76.0% | 92.0% |