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regulatory_protein_IE1

Euk-Vir

Cercopithecine_betaherpesvirus_5

regulatory_protein_IE1__YP_004936081__Cercopithecine_betaherpesvirus_5__50292

Identity

Accession:
YP_004936081 ↗
Protein ID:
regulatory_protein_IE1
Kingdom:
euk

Quality

62.1 mean pLDDT

Taxonomy

Heunggongvirae› Peploviricota› Herviviricetes› Herpesvirales› Orthoherpesviridae› Cytomegalovirus› Cercopithecine_betaherpesvirus_5

TaxID: 50292

Cluster

Singleton — not in a non-trivial cluster

3D Structure

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Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 84-159
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF07340.17 best Herpes_IE1 114.0 1.40e-32 100.0% 19.6%
CATH (1)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2clyB00 6.10.280.70 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.65 47.0 3.99e-01 75.0% 97.5%
ECOD (1)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3712975 2004.1.1.208 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_33 0.62 58.0 3.88e-01 100.0% 29.8%
D2 medium residues 160-342
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF07340.17 best Herpes_IE1 309.4 6.00e-92 100.0% 47.9%
CATH (56)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1dd5A01 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.85 38.0 4.98e-01 77.6% 73.4%
3s84A02 1.20.120.20 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein 0.80 47.0 5.12e-01 71.6% 68.2%
4ke2A00 6.10.140.1860 Special › Helix non-globular › Helix Hairpins › 0.74 61.0 5.97e-01 85.8% 98.5%
3lbxB01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.74 27.0 3.60e-01 79.8% 58.9%
2ieqA00 1.20.5.300 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.69 33.0 4.64e-01 79.8% 93.2%
7zo9A01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.69 44.0 3.68e-01 88.5% 37.1%
3tbiB02 6.10.140.1670 Special › Helix non-globular › Helix Hairpins › 0.68 38.0 5.10e-01 86.9% 100.0%
4gnkE00 1.20.1230.10 Mainly Alpha › Up-down Bundle › Phospholipase C Beta; Chain: A › Phospholipase C beta, distal C-terminal domain 0.68 53.0 4.88e-01 82.0% 63.0%
1jadA00 1.20.1230.10 Mainly Alpha › Up-down Bundle › Phospholipase C Beta; Chain: A › Phospholipase C beta, distal C-terminal domain 0.65 61.0 5.48e-01 98.9% 79.8%
2oduA02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.65 28.0 3.70e-01 70.5% 70.5%
3fb2A01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.65 27.0 3.50e-01 76.0% 64.8%
4l0rB00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.64 27.0 4.18e-01 76.5% 97.3%
4dylA02 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.62 29.0 3.91e-01 77.6% 83.0%
4dylA01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.62 57.0 5.15e-01 99.5% 78.0%
4akvA02 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.62 50.0 5.02e-01 95.1% 82.1%
1fewA00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.61 37.0 3.80e-01 92.9% 61.3%
2odvA01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.61 27.0 3.42e-01 82.5% 67.0%
1cunA01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.61 27.0 3.61e-01 90.2% 74.5%
3snhA02 1.20.120.1240 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Dynamin, middle domain 0.60 41.0 3.92e-01 100.0% 58.3%
4nooB00 1.10.8.1160 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.60 27.0 3.67e-01 100.0% 80.0%
1qu7A00 1.10.287.950 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein 0.60 43.0 4.03e-01 73.2% 59.9%
4nswB01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.60 53.0 4.69e-01 98.9% 66.8%
5gj7A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.60 32.0 3.49e-01 95.6% 60.9%
2oexA01 1.20.120.560 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › alix/aip1 in complex with the ypdl late domain 0.59 39.0 4.31e-01 100.0% 83.2%
4fzsA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.59 41.0 3.91e-01 72.7% 60.3%
1s35A02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.59 28.0 3.52e-01 92.9% 72.7%
3m9vA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.59 31.0 3.34e-01 94.0% 57.3%
3g67A00 1.10.287.950 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein 0.59 42.0 4.08e-01 73.2% 67.1%
4wpeA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.59 55.0 4.76e-01 100.0% 76.7%
6xj1A01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.59 54.0 4.92e-01 99.5% 81.6%
3qweA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.59 54.0 4.79e-01 100.0% 78.5%
7aalA01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.58 54.0 4.76e-01 100.0% 78.9%
4mh6A00 1.10.287.1700 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.58 43.0 4.60e-01 76.0% 100.0%
4jioA01 1.20.120.560 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › alix/aip1 in complex with the ypdl late domain 0.58 40.0 4.24e-01 100.0% 79.5%
4ijjB00 1.20.120.910 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › DksA, coiled-coil domain 0.57 30.0 3.57e-01 71.6% 71.5%
2v0oB00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.57 53.0 4.62e-01 100.0% 73.4%
2ch7A00 1.10.287.950 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein 0.57 41.0 3.49e-01 73.8% 48.5%
4cgkA01 6.10.250.3150 Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.56 39.0 3.73e-01 71.0% 64.5%
3ok8A00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.56 50.0 4.70e-01 100.0% 80.8%
7p3rA01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.55 49.0 4.02e-01 95.1% 76.0%
2ficB00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.55 45.0 4.36e-01 95.1% 78.1%
6iknD01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.55 50.0 4.42e-01 100.0% 73.8%
2dq0A01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.54 32.0 3.99e-01 97.3% 97.2%
3cazB00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.54 47.0 4.50e-01 100.0% 82.4%
3vkgA12 1.10.287.2610 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.53 45.0 4.28e-01 89.1% 79.5%
3u0cA00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.53 37.0 4.02e-01 71.0% 85.4%
2efkA01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.53 49.0 4.33e-01 100.0% 82.1%
1g8xA06 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.53 40.0 3.36e-01 79.2% 56.4%
3i9wA00 1.20.58.920 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.53 48.0 4.20e-01 98.9% 91.5%
1uruA01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.52 45.0 4.31e-01 100.0% 79.4%
2rd0B00 1.10.287.1490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.52 36.0 4.07e-01 86.9% 92.8%
2oexA02 1.20.140.50 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › alix/aip1 like domains 0.52 39.0 3.81e-01 92.9% 71.6%
6bl6B01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.51 46.0 3.79e-01 95.1% 75.6%
1avoB00 1.20.120.180 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Proteasome activator pa28, C-terminal domain 0.51 33.0 3.68e-01 98.9% 82.1%
2d1lA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.51 46.0 4.18e-01 99.5% 76.3%
4y9jA01 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.50 29.0 3.16e-01 97.8% 67.1%
ECOD (66)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
2711996 6168.1.1.1 ↗ alpha duplicates or obligate multimers › Immediate-early 1 protein › Immediate-early 1 protein › Immediate-early 1 protein › Herpes_IE1 0.84 80.0 6.31e-01 100.0% 52.6%
1406537 6168.1.1.1 ↗ alpha duplicates or obligate multimers › Immediate-early 1 protein › Immediate-early 1 protein › Immediate-early 1 protein › Herpes_IE1 0.84 79.0 6.22e-01 100.0% 51.8%
3733682 4177.1.1.0 ↗ alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.77 65.0 5.76e-01 88.0% 65.5%
3940963 4177.1.1.0 ↗ alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.76 62.0 5.32e-01 85.8% 57.2%
3517583 4177.1.1.26 ↗ alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › PKK 0.75 56.0 5.48e-01 77.0% 73.5%
3577242 604.1.1.1 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.74 28.0 3.64e-01 81.4% 58.2%
3391705 4177.1.1.1 ↗ alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH 0.74 55.0 4.63e-01 75.4% 75.5%
3484907 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.72 29.0 3.56e-01 78.1% 55.8%
3389635 601.19.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein 0.71 59.0 4.71e-01 88.0% 79.3%
5062884 4177.1.1.0 ↗ alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.70 60.0 5.68e-01 100.0% 77.6%
3908132 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.69 50.0 4.44e-01 73.2% 67.3%
5031890 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.69 58.0 5.26e-01 88.5% 82.0%
3923798 4177.1.1.0 ↗ alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.69 48.0 4.45e-01 71.6% 75.3%
3170937 4177.1.1.1 ↗ alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH 0.66 61.0 5.30e-01 99.5% 81.5%
3755118 604.1.1.1 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.65 30.0 3.68e-01 74.9% 67.0%
3400767 4177.1.1.0 ↗ alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.64 60.0 4.92e-01 100.0% 61.3%
3928718 5086.1.1.0 ↗ alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.63 47.0 5.23e-01 79.2% 100.0%
3587916 1075.4.1.1 ↗ alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane 0.63 39.0 3.26e-01 87.4% 35.6%
4020850 3758.1.1.0 ↗ alpha bundles › Bacterial hemolysins-like › Bacterial hemolysins › Bacterial hemolysins 0.62 43.0 3.72e-01 71.0% 52.0%
3921802 5086.1.1.0 ↗ alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.61 43.0 4.56e-01 71.6% 89.7%
3494796 4177.1.1.0 ↗ alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.61 57.0 4.94e-01 99.5% 76.7%
3604446 2004.1.1.480 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_21, AAA_29 0.61 46.0 3.16e-01 77.0% 41.0%
3607135 5086.1.1.0 ↗ alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.59 38.0 4.33e-01 73.2% 85.9%
4345467 2004.1.1.87 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N 0.59 50.0 3.70e-01 90.2% 37.0%
3989648 1203.1.2.17 ↗ alpha bundles › Shroom domain 2 › Shroom domain 2 › Human SD2 › ABC_membrane 0.59 41.0 3.99e-01 99.5% 63.5%
3170491 4177.1.1.0 ↗ alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.59 54.0 5.06e-01 99.5% 81.8%
3894262 4177.1.1.1 ↗ alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH 0.58 54.0 4.53e-01 100.0% 68.5%
3630257 4177.1.1.0 ↗ alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.58 47.0 4.81e-01 98.9% 87.2%
3414779 4177.1.1.1 ↗ alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH 0.58 53.0 4.70e-01 100.0% 74.3%
3760483 603.1.1.0 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.58 38.0 3.79e-01 93.4% 62.6%
3239667 2004.1.1.87 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N 0.57 44.0 2.95e-01 79.2% 58.5%
4930606 192.2.1.0 ↗ alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.57 48.0 3.85e-01 89.6% 53.4%
3779599 5086.1.1.0 ↗ alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.57 47.0 3.53e-01 89.1% 75.7%
3795763 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.56 46.0 3.47e-01 89.6% 75.5%
3337008 192.2.1.60 ↗ alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › KIF21A_4th 0.56 41.0 4.70e-01 87.4% 100.0%
5040840 2004.1.1.87 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N 0.55 44.0 2.98e-01 84.7% 58.2%
3271160 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.55 48.0 4.57e-01 95.1% 94.1%
4927671 5086.1.1.0 ↗ alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.55 47.0 4.35e-01 89.1% 89.8%
3602122 3922.1.1.0 ↗ alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.55 46.0 3.73e-01 88.5% 91.8%
3408532 5086.1.1.0 ↗ alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.55 46.0 4.79e-01 89.1% 95.9%
3970019 3755.4.1.0 ↗ alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.55 41.0 3.77e-01 76.0% 92.6%
3193556 2004.1.1.481 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_29 0.54 44.0 2.93e-01 85.8% 59.2%
3592681 4177.1.1.0 ↗ alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.54 50.0 4.15e-01 100.0% 62.5%
4989878 2004.1.1.87 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N 0.54 45.0 3.10e-01 86.3% 47.9%
3402026 2004.1.1.199 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23,SbcC_Walker_B 0.54 47.0 3.40e-01 94.0% 53.0%
4260979 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.54 45.0 3.97e-01 89.1% 67.5%
4001188 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.54 45.0 3.49e-01 92.3% 73.6%
4418753 3755.3.1.363 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › T1-F 0.54 45.0 3.88e-01 89.6% 62.5%
4153184 5086.1.1.0 ↗ alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.53 41.0 4.22e-01 80.9% 81.7%
3410024 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.53 44.0 3.89e-01 87.4% 66.0%
3503775 4177.1.1.2 ↗ alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR 0.53 45.0 4.18e-01 100.0% 72.0%
4136919 192.2.1.0 ↗ alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.53 43.0 4.35e-01 85.8% 97.8%
4324117 3755.4.1.0 ↗ alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.53 45.0 3.63e-01 90.2% 82.3%
3379082 2004.1.1.433 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_23 0.53 43.0 3.00e-01 85.8% 46.9%
4471073 5086.1.1.0 ↗ alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.53 44.0 3.52e-01 89.1% 53.8%
3167884 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.53 44.0 4.10e-01 89.1% 78.7%
3847361 4177.1.1.2 ↗ alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR 0.52 45.0 4.07e-01 99.5% 69.0%
3898401 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.52 38.0 3.43e-01 86.3% 55.5%
3386700 304.58.1.0 ↗ a+b two layers › Alpha-beta plaits › FepE-like › FepE-like 0.52 47.0 4.05e-01 100.0% 90.8%
5036915 5086.1.1.0 ↗ alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.51 43.0 3.80e-01 90.2% 69.3%
4537898 3922.1.1.0 ↗ alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.51 41.0 3.60e-01 85.8% 99.6%
3611166 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.51 43.0 4.21e-01 89.1% 85.5%
3628737 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.51 39.0 3.58e-01 85.8% 61.3%
3538954 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.50 42.0 3.65e-01 88.5% 79.3%
5020818 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.50 44.0 3.23e-01 93.4% 45.8%
4939828 3922.1.1.0 ↗ alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.50 42.0 3.45e-01 89.1% 50.1%
D3 medium residues 343-401
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF07340.17 best Herpes_IE1 83.0 3.70e-23 100.0% 15.2%
CATH (16)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3acxA00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.69 50.0 3.19e-01 76.3% 27.1%
1a3qA01 2.60.40.340 Mainly Beta › Sandwich › Immunoglobulin-like › Rel homology domain (RHD), DNA-binding domain 0.68 48.0 3.42e-01 76.3% 24.6%
6b1pA03 1.10.1160.10 Mainly Alpha › Orthogonal Bundle › Glutamyl-tRNA Synthetase; domain 2 › Glutamyl-trna Synthetase; Domain 2 0.63 46.0 4.16e-01 79.7% 77.1%
3iylB02 1.10.2050.10 Mainly Alpha › Orthogonal Bundle › Protein mu-1, chain B, domain 3 › Protein mu-1, chain B, domain 3 0.63 49.0 3.80e-01 86.4% 64.9%
3ooqA02 3.20.20.140 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Metal-dependent hydrolases 0.62 46.0 2.98e-01 81.4% 43.3%
4xgqA00 3.40.50.1010 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 5'-nuclease 0.61 41.0 3.20e-01 74.6% 31.1%
2yveB00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.60 46.0 3.32e-01 83.1% 44.2%
1mswD01 1.10.1320.10 Mainly Alpha › Orthogonal Bundle › T7 RNA polymerase; domain 1 › DNA-directed RNA polymerase, N-terminal domain 0.60 52.0 3.29e-01 100.0% 19.4%
1ql3A00 1.10.760.10 Mainly Alpha › Orthogonal Bundle › Cytochrome Bc1 Complex; Chain D, domain 2 › Cytochrome c-like domain 0.58 39.0 3.34e-01 71.2% 44.4%
3whjA00 6.10.140.1710 Special › Helix non-globular › Helix Hairpins › 0.57 46.0 3.78e-01 89.8% 57.7%
1x9fD00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.57 44.0 3.41e-01 86.4% 77.9%
3natA01 3.40.50.11250 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Protein of unknown function DUF3013 0.56 48.0 3.63e-01 100.0% 39.5%
5afdA00 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.55 45.0 2.87e-01 89.8% 25.7%
3b8xA02 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.55 41.0 3.28e-01 81.4% 92.7%
4opmA00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.52 45.0 2.92e-01 100.0% 93.6%
5jtfB00 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.51 36.0 2.67e-01 74.6% 26.3%
ECOD (14)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4978734 5054.1.1.0 ↗ alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels 0.65 52.0 3.81e-01 89.8% 41.2%
3532102 4336.2.1.4 ↗ alpha duplicates or obligate multimers › YheA/YmcA-like › Protein SUS1 › Protein SUS1 › CEP76_N 0.65 54.0 5.32e-01 96.6% 86.2%
3039954 3226.1.1.1 ↗ alpha complex topology › Uracil Transporter UraA › Uracil Transporter UraA › Uracil Transporter UraA › Xan_ur_permease 0.60 47.0 4.19e-01 91.5% 71.3%
3720763 5086.1.1.169 ↗ alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › NCA2 0.59 48.0 3.50e-01 91.5% 52.4%
3705211 261.1.1.1 ↗ a+b complex topology › Hect, E3 ligase catalytic domain › Hect, E3 ligase catalytic domain › Hect, E3 ligase catalytic domain › HECT 0.58 42.0 2.56e-01 79.7% 25.4%
3516926 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.57 45.0 3.07e-01 88.1% 24.3%
1148128 622.5.1.1 ↗ alpha bundles › YvfG-like › Probable 26S proteasome regulatory subunit p27 › Probable 26S proteasome regulatory subunit p27 › Nas2_N 0.57 46.0 3.78e-01 89.8% 57.7%
3595721 5.1.4.169 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › Beta-prop_RSE1_2nd 0.57 49.0 2.97e-01 100.0% 51.8%
4092726 2003.1.2.8 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain › FAD_binding_2,Pyr_redox_2 0.56 46.0 3.22e-01 96.6% 29.5%
3511643 148.1.3.19 ↗ alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › AAA_lid_3 0.56 49.0 4.35e-01 100.0% 97.6%
4196235 159.1.1.1 ↗ alpha bundles › all-alpha NTP pyrophosphatases › all-alpha NTP pyrophosphatases › Hypothetical protein AF_0060 › MazG 0.56 43.0 3.74e-01 88.1% 62.0%
396482 3147.1.1.1 ↗ a+b two layers › Uncharacterized protein EF_1977 › Uncharacterized protein EF_1977 › Uncharacterized protein EF_1977 › DUF3013 0.54 46.0 3.59e-01 100.0% 42.1%
4283815 1.1.9.5 ↗ beta barrels › cradle loop barrel › RIFT-related › PUA domain › LON_substr_bdg 0.54 43.0 2.94e-01 96.6% 30.0%
3712226 101.1.1.67 ↗ alpha arrays › HTH › HTH › Three-helical HTH › Myb_DNA-bind_6 0.52 43.0 3.81e-01 98.3% 92.6%