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rep_protein

Euk-Vir

Adeno-associated_virus

rep_protein__YP_009552823__Adeno-associated_virus__272636

Identity

Accession:
YP_009552823 ↗
Protein ID:
rep_protein
Kingdom:
euk

Quality

71.3 mean pLDDT

Taxonomy

Shotokuvirae› Cossaviricota› Quintoviricetes› Piccovirales› Parvoviridae› Dependoparvovirus› Adeno-associated_virus

TaxID: 272636

Cluster

View cluster (29 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 5-197
PDB
Domain cluster: rep: NS1__YP_009507375__Chipmunk_parvovirus__56820__D1-203
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF08724.17 best Rep_N 230.8 1.60e-68 97.4% 99.5%
CATH (39)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1m55A00 3.40.1310.20 Alpha Beta › 3-Layer(aba) Sandwich › Replication Protein E1; Chain: A, › 0.93 89.0 8.98e-01 100.0% 99.0%
6usmB01 3.40.1310.20 Alpha Beta › 3-Layer(aba) Sandwich › Replication Protein E1; Chain: A, › 0.75 56.0 6.32e-01 84.5% 100.0%
2lqjA00 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.75 35.0 4.98e-01 78.8% 91.5%
2k3iA01 3.30.70.860 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.75 34.0 5.04e-01 72.5% 96.5%
5t0oA02 3.30.70.1430 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Multidrug efflux transporter AcrB pore domain 0.75 40.0 5.38e-01 87.0% 98.1%
4mt1A02 3.30.70.1430 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Multidrug efflux transporter AcrB pore domain 0.74 40.0 5.36e-01 87.0% 98.1%
2x3gA00 3.30.70.1910 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.73 39.0 4.96e-01 93.8% 86.2%
4kw3A00 3.40.1310.20 Alpha Beta › 3-Layer(aba) Sandwich › Replication Protein E1; Chain: A, › 0.72 67.0 5.99e-01 100.0% 97.0%
3b82A06 3.30.70.240 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.70 30.0 3.75e-01 76.2% 62.8%
2od4B01 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.70 34.0 4.76e-01 74.6% 97.8%
1r89A03 3.30.70.590 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Poly(A) polymerase predicted RNA binding domain 0.70 43.0 5.10e-01 97.4% 88.1%
2kjwA00 3.30.70.60 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S6/Translation elongation factor EF1B 0.70 33.0 4.58e-01 74.6% 89.6%
2rrnA01 3.30.70.2040 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.69 31.0 4.64e-01 75.1% 97.6%
2r7rA04 3.30.70.2480 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.68 38.0 4.16e-01 81.3% 66.2%
2jgbA01 3.30.760.10 Alpha Beta › 2-Layer Sandwich › RNA Cap, Translation Initiation Factor Eif4e › RNA Cap, Translation Initiation Factor Eif4e 0.68 35.0 3.71e-01 79.3% 53.8%
4djbA00 3.30.70.2870 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Mastadenovirus E4 ORF3 0.68 41.0 5.11e-01 76.7% 97.5%
1j27A00 3.30.70.1120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › TT1725-like 0.68 35.0 4.70e-01 75.1% 95.9%
2pd1A01 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.67 34.0 4.61e-01 75.6% 95.8%
3kg0A00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.67 35.0 4.70e-01 99.5% 96.9%
3n79A01 3.30.70.1710 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › BMC (bacterial microcompartment) domain 0.67 30.0 4.41e-01 76.2% 100.0%
4er8A00 3.30.70.1290 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Transposase IS200-like 0.66 48.0 5.14e-01 96.9% 86.1%
2dbbA02 3.30.70.920 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Lrp/AsnC effector binding domain/regulation of amino acid metabolism (RAM) domain 0.66 33.0 4.53e-01 96.4% 96.8%
1f08B00 3.40.1310.10 Alpha Beta › 3-Layer(aba) Sandwich › Replication Protein E1; Chain: A, › 0.65 40.0 4.51e-01 100.0% 78.6%
2fb0A00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.65 33.0 4.45e-01 75.6% 95.7%
1r9wA00 3.40.1310.10 Alpha Beta › 3-Layer(aba) Sandwich › Replication Protein E1; Chain: A, › 0.65 39.0 4.54e-01 99.5% 82.6%
1iujA00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.65 35.0 4.66e-01 88.6% 99.0%
2gffA00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.64 33.0 4.50e-01 76.7% 97.9%
2bbeA00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.64 34.0 4.39e-01 100.0% 92.2%
3e8oB00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.64 35.0 4.59e-01 99.5% 100.0%
1lq9A00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.63 36.0 4.51e-01 99.0% 94.6%
5ixuA00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.62 34.0 4.46e-01 87.6% 99.0%
1pbuA00 3.30.70.1010 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Translation elongation factor EF1B, gamma chain, conserved domain 0.61 38.0 4.15e-01 87.0% 73.5%
3mcnA01 3.30.70.560 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK 0.57 42.0 4.73e-01 91.7% 98.6%
4dmzA02 3.30.70.2880 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.56 37.0 4.33e-01 100.0% 93.4%
4ndhB00 3.30.428.10 Alpha Beta › 2-Layer Sandwich › HIT family, subunit A › HIT-like 0.54 34.0 3.56e-01 100.0% 68.0%
2joeA01 3.30.1830.10 Alpha Beta › 2-Layer Sandwich › YehR-like fold › YehR-like 0.53 29.0 3.51e-01 71.0% 79.7%
3go9A02 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.51 37.0 3.60e-01 73.6% 88.5%
6ofsA02 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.51 37.0 3.56e-01 73.6% 90.4%
3w3sA01 3.30.70.1920 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.51 37.0 3.92e-01 74.6% 88.7%
ECOD (34)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4880004 304.55.1.7 ↗ a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Origin of replication-binding domains › Rep_N 0.94 91.0 8.86e-01 100.0% 93.3%
1491756 304.55.1.9 ↗ a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Origin of replication-binding domains › PV_NSP1 0.81 76.0 6.86e-01 98.4% 92.7%
2834623 304.55.1.7 ↗ a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Origin of replication-binding domains › Rep_N 0.78 67.0 7.00e-01 96.9% 100.0%
4959045 304.8.1.81 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › REP_ORF2-G2P 0.74 47.0 5.32e-01 89.6% 82.0%
3973625 304.28.1.0 ↗ a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain 0.73 37.0 5.15e-01 74.6% 98.9%
4098707 304.159.1.1 ↗ a+b two layers › Alpha-beta plaits › Alpha-beta plait domain in NisB › Alpha-beta plait domain in NisB › Lant_dehydr_C 0.73 36.0 4.89e-01 78.8% 91.0%
4997522 304.12.1.0 ↗ a+b two layers › Alpha-beta plaits › Ribosomal protein S6 › Ribosomal protein S6 0.73 32.0 4.84e-01 74.1% 98.8%
4031210 304.159.1.1 ↗ a+b two layers › Alpha-beta plaits › Alpha-beta plait domain in NisB › Alpha-beta plait domain in NisB › Lant_dehydr_C 0.72 37.0 4.89e-01 98.4% 89.5%
2843481 304.12.1.0 ↗ a+b two layers › Alpha-beta plaits › Ribosomal protein S6 › Ribosomal protein S6 0.71 34.0 4.81e-01 75.6% 98.8%
3952812 304.4.1.0 ↗ a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.70 35.0 4.83e-01 86.5% 98.9%
4944179 304.43.1.0 ↗ a+b two layers › Alpha-beta plaits › Hypothetical protein TT1725 › Hypothetical protein TT1725 0.69 37.0 4.93e-01 74.6% 99.0%
5059197 304.55.2.1 ↗ a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Transposase IS200-like › Y1_Tnp 0.68 45.0 5.16e-01 87.0% 90.7%
1146572 304.152.1.1 ↗ a+b two layers › Alpha-beta plaits › E4-ORF3 › E4-ORF3 › Adeno_E4_ORF3 0.68 41.0 5.15e-01 76.7% 99.1%
5052583 304.8.1.0 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.67 34.0 4.48e-01 75.6% 88.6%
151843 304.55.2.0 ↗ a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Transposase IS200-like 0.66 48.0 5.14e-01 96.9% 86.1%
4032691 304.150.1.1 ↗ a+b two layers › Alpha-beta plaits › Adapter protein mecA 2 C-terminal domain › Adapter protein mecA 2 C-terminal domain › MecA 0.66 32.0 4.28e-01 87.0% 89.5%
4059360 304.9.1.71 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › SNU71_RBD 0.66 34.0 4.49e-01 73.6% 93.0%
2791434 304.55.1.10 ↗ a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Origin of replication-binding domains › PPV_E1_DBD 0.66 39.0 4.41e-01 99.5% 75.0%
5039525 304.4.1.4 ↗ a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › ABM 0.65 32.0 4.51e-01 73.6% 98.9%
4167612 304.150.1.1 ↗ a+b two layers › Alpha-beta plaits › Adapter protein mecA 2 C-terminal domain › Adapter protein mecA 2 C-terminal domain › MecA 0.65 32.0 4.35e-01 91.2% 90.0%
5112 304.55.1.10 ↗ a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Origin of replication-binding domains › PPV_E1_DBD 0.65 39.0 4.54e-01 99.5% 82.6%
4133039 304.8.1.81 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › REP_ORF2-G2P 0.64 47.0 5.05e-01 87.0% 87.3%
3588331 304.150.1.1 ↗ a+b two layers › Alpha-beta plaits › Adapter protein mecA 2 C-terminal domain › Adapter protein mecA 2 C-terminal domain › MecA 0.62 31.0 4.26e-01 91.2% 94.7%
4350848 304.150.1.1 ↗ a+b two layers › Alpha-beta plaits › Adapter protein mecA 2 C-terminal domain › Adapter protein mecA 2 C-terminal domain › MecA 0.62 31.0 4.22e-01 90.7% 94.7%
4412768 304.4.1.0 ↗ a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.59 33.0 3.94e-01 89.1% 80.8%
4511949 304.48.1.74 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Phage_GPA 0.57 48.0 4.49e-01 88.6% 76.2%
5078562 304.55.2.1 ↗ a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Transposase IS200-like › Y1_Tnp 0.57 47.0 4.78e-01 98.4% 89.2%
None — 0.57 49.0 4.47e-01 90.2% 85.3%
3971826 309.1.1.4 ↗ a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase › Peptidase_M16_C 0.54 40.0 3.93e-01 75.6% 79.5%
4173640 304.55.1.27 ↗ a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Origin of replication-binding domains › Phage_GPA 0.54 49.0 4.36e-01 97.9% 80.4%
4170426 304.8.1.70 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › Phage_GPA 0.53 49.0 4.28e-01 100.0% 79.6%
3340749 309.1.1.11 ↗ a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase › PqqF-like_C_4 0.53 38.0 3.59e-01 74.1% 83.4%
3430240 323.1.1.7 ↗ a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › Transferase 0.52 37.0 3.05e-01 73.1% 51.4%
1182828 309.1.1.0 ↗ a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase 0.51 37.0 3.61e-01 73.6% 88.9%
D2 medium residues 215-278
PDB
Domain cluster: rep: Rep_68_protein__YP_680422__adeno-associated_virus_2__10804__D219-282
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF01057.24 best Parvo_NS1 58.6 6.80e-16 93.8% 21.0%
D3 medium residues 327-453
PDB
Domain cluster: rep: MN062720.1__QDP45567.1__SEA_FUZZBUSTER_83__00083__D568-722_747-764
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF01057.24 best Parvo_NS1 239.4 5.30e-71 100.0% 46.1%
PF00519.24 PPV_E1_C 26.6 4.60e-06 89.8% 35.6%