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replicase

Euk-Vir

Cowpea_mottle_virus

replicase__NP_619521__Cowpea_mottle_virus__12627

Identity

Accession:: NP_619521 ↗
Protein ID:: replicase
Kingdom:: euk

Quality

83.5 mean pLDDT

Cluster

View cluster (58 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 593-735

PDB

Domain cluster: rep: P95_replicase__YP_009259667__Pelargonium_leaf_curl_virus__35280__D527-559_693-852

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF00998.29 best	RdRP_3	120.9	8.90e-35	93.7%	27.8%

D2 medium residues 54-172

PDB

Domain cluster: rep: RNA-dependent_RNA-polymerase__YP_009116634__Elderberry_latent_virus__167018__D80-183

CATH (16)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
2dofA00	1.10.10.440	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › FF domain	0.61	39.0	4.43e-01	78.2%	89.4%
4h9nC00	1.20.58.2170	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.60	39.0	3.29e-01	84.0%	37.6%
1ls1A01	1.20.120.140	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › SRP54, nucleotide-binding domain	0.58	35.0	4.04e-01	73.1%	80.9%
1t98A01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.58	38.0	4.29e-01	82.4%	89.7%
1j3eA00	1.20.1380.10	Mainly Alpha › Up-down Bundle › Replication modulator SeqA, C-terminal DNA-binding domain › Replication modulator SeqA, C-terminal DNA-binding domain	0.57	33.0	3.39e-01	88.2%	57.4%
1tt5B02	1.10.10.520	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Ubiquitin activating enzymes (Uba3). Chain: B, domain 2	0.57	36.0	4.26e-01	74.8%	98.7%
3vfcA01	3.30.390.10	Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain	0.57	39.0	3.65e-01	83.2%	56.4%
7e5aB02	1.20.1000.10	Mainly Alpha › Up-down Bundle › Signaling Protein - Interferon-induced Guanylate-binding Protein 1; Chain A, domain 1 › Guanylate-binding protein, C-terminal domain	0.57	40.0	3.65e-01	73.9%	56.1%
3fbzA01	1.20.58.800	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.55	39.0	4.21e-01	77.3%	86.3%
2go7A02	1.10.150.240	Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2	0.55	28.0	3.51e-01	81.5%	83.6%
2klqA00	1.20.58.870	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.53	39.0	3.97e-01	75.6%	96.5%
1wgwA00	1.20.120.140	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › SRP54, nucleotide-binding domain	0.52	33.0	3.63e-01	70.6%	76.8%
1dlwA00	1.10.490.10	Mainly Alpha › Orthogonal Bundle › Globin-like › Globins	0.51	39.0	4.04e-01	82.4%	97.4%
6bmeA00	1.10.490.10	Mainly Alpha › Orthogonal Bundle › Globin-like › Globins	0.51	36.0	3.58e-01	73.9%	99.2%
1f16A00	1.10.437.10	Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like	0.50	38.0	3.29e-01	79.8%	52.1%
3rmiA00	1.20.59.10	Mainly Alpha › Up-down Bundle › Chorismate Mutase Domain, subunit A › Chorismate mutase	0.50	36.0	3.76e-01	73.9%	83.8%

ECOD (17)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3952621	101.35.1.0 ↗	alpha arrays › HTH › DNA repair regulatory protein RecX › DNA repair regulatory protein RecX	0.77	45.0	5.72e-01	70.6%	100.0%
4124450	101.35.1.4 ↗	alpha arrays › HTH › DNA repair regulatory protein RecX › DNA repair regulatory protein RecX › RecX_HTH3	0.75	44.0	5.52e-01	70.6%	100.0%
3170802	101.1.1.133 ↗	alpha arrays › HTH › HTH › Three-helical HTH › Vhr1	0.68	49.0	5.33e-01	97.5%	93.7%
3171699	101.1.1.133 ↗	alpha arrays › HTH › HTH › Three-helical HTH › Vhr1	0.66	49.0	5.23e-01	99.2%	92.0%
3492885	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.60	39.0	4.55e-01	95.0%	98.8%
4014527	532.2.1.0 ↗	alpha arrays › Type III secretion system domain-like › Type III secretion system domains › Type III secretion system domains	0.58	41.0	4.54e-01	74.8%	94.7%
3988991	181.1.1.1 ↗	alpha bundles › Domain of the SRP/SRP receptor G proteins-like › Domain of the SRP/SRP receptor G-proteins › Domain of the SRP/SRP receptor G-proteins › SRP54_N	0.56	35.0	3.93e-01	74.8%	81.1%
3699724	650.1.1.1 ↗	alpha bundles › Chaperone J-domain › Chaperone J-domain › Chaperone J-domain › DnaJ	0.55	33.0	4.04e-01	84.9%	98.6%
3968363	650.1.1.1 ↗	alpha bundles › Chaperone J-domain › Chaperone J-domain › Chaperone J-domain › DnaJ	0.54	28.0	3.69e-01	77.3%	98.3%
3944250	7516.1.1.2 ↗	a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2	0.53	39.0	3.10e-01	74.8%	76.5%
4934951	164.1.1.1 ↗	alpha bundles › Chorismate mutase II › Chorismate mutase II › Chorismate mutase II › CM_2	0.52	34.0	3.76e-01	71.4%	85.6%
4357455	650.1.1.1 ↗	alpha bundles › Chaperone J-domain › Chaperone J-domain › Chaperone J-domain › DnaJ	0.52	34.0	3.95e-01	89.1%	94.1%
4093848	3584.1.1.1 ↗	alpha arrays › DNA polymerase III finger domain › DNA polymerase III finger domain › DNA polymerase III finger domain › DNA_pol3_finger	0.52	45.0	3.71e-01	95.8%	52.9%
3789554	604.12.1.0 ↗	alpha bundles › Spectrin repeat-like › MIT domain › MIT domain	0.52	36.0	4.11e-01	84.0%	96.7%
None	—		0.52	45.0	3.35e-01	96.6%	50.0%
5055634	633.12.1.1 ↗	alpha bundles › Bromodomain-like › Ta0600-like › Ta0600-like › UPF0147	0.51	31.0	3.63e-01	83.2%	88.7%
3677602	650.1.1.1 ↗	alpha bundles › Chaperone J-domain › Chaperone J-domain › Chaperone J-domain › DnaJ	0.51	30.0	3.39e-01	84.9%	78.8%

D3 medium residues 174-214

PDB

Domain cluster: representative

CATH (2)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
2fupA00	1.20.58.300	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › FlgN-like	0.61	41.0	2.92e-01	70.7%	36.2%
1w99A01	1.20.190.10	Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › Pesticidal crystal protein, N-terminal domain	0.52	39.0	2.80e-01	100.0%	96.0%

ECOD (1)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3899400	633.4.1.14 ↗	alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PCAF_N	0.52	37.0	2.70e-01	87.8%	25.0%

D4 medium residues 302-374_461-518

PDB

Domain cluster: rep: replicase__YP_002333476__Soybean_yellow_mottle_mosaic_virus__578361__D327-366_395-422_476-495

Pfam (2)

Accession	Name	Score	E-value	Q cov	HMM cov
PF00998.29 best	RdRP_3	64.4	1.20e-17	56.5%	14.6%
PF00998.29	RdRP_3	77.3	1.50e-21	45.0%	11.9%

D5 medium residues 422-460_519-592

PDB

Domain cluster: rep: hypothetical_protein_1__YP_009337274__Changjiang_tombus-like_virus_14__1922807__D158-196_253-344

Pfam (2)

Accession	Name	Score	E-value	Q cov	HMM cov
PF00998.29 best	RdRP_3	106.9	1.60e-30	67.3%	16.3%
PF00998.29	RdRP_3	51.6	9.50e-14	35.4%	8.0%