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replicase
Euk-VirPorcine_parvovirus_4
replicase__YP_004013956__Porcine_parvovirus_4__707546
Identity
- Accession:
- YP_004013956 ↗
- Protein ID:
- replicase
- Kingdom:
- euk
Quality
76.9
mean pLDDT
Taxonomy
Shotokuvirae›
Cossaviricota›
Quintoviricetes›
Piccovirales›
Parvoviridae›
Copiparvovirus›
Porcine_parvovirus_4
TaxID: 707546
Cluster
View cluster (29 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 13-209
Domain cluster:
rep: NS1__YP_009507375__Chipmunk_parvovirus__56820__D1-203
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF08724.17 best | Rep_N | 40.6 | 3.30e-10 | 79.2% | 74.2% |
D2
high
residues 349-483
Domain cluster:
rep: MN062720.1__QDP45567.1__SEA_FUZZBUSTER_83__00083__D568-722_747-764
Pfam (2)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF01057.24 best | Parvo_NS1 | 198.7 | 1.30e-58 | 100.0% | 49.8% |
| PF00519.24 | PPV_E1_C | 37.0 | 3.00e-09 | 97.0% | 42.2% |
D3
medium
residues 219-288
Domain cluster:
rep: Rep_68_protein__YP_680422__adeno-associated_virus_2__10804__D219-282
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF01057.24 best | Parvo_NS1 | 29.0 | 7.40e-07 | 88.6% | 21.0% |
CATH (29)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1u0jA01 | 1.10.10.950 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › | 0.83 | 62.0 | 6.92e-01 | 78.6% | 100.0% |
| 3dt5A00 | 1.10.3940.10 | Mainly Alpha › Orthogonal Bundle › AF_0924 fold › AF_0924 domain | 0.68 | 46.0 | 3.81e-01 | 70.0% | 71.4% |
| 1werA01 | 1.10.506.10 | Mainly Alpha › Orthogonal Bundle › GTPase Activation - p120GAP; domain 1 › GTPase Activation - p120gap; domain 1 | 0.66 | 58.0 | 4.31e-01 | 98.6% | 91.5% |
| 2iw3A02 | 1.20.1390.20 | Mainly Alpha › Up-down Bundle › PWI domain › | 0.62 | 49.0 | 4.56e-01 | 87.1% | 67.8% |
| 4c9bB00 | 1.25.40.180 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.62 | 54.0 | 3.67e-01 | 100.0% | 44.4% |
| 3dkrA00 | 3.40.50.1820 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain | 0.62 | 52.0 | 3.63e-01 | 95.7% | 75.5% |
| 2nt2A00 | 3.90.190.10 | Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily | 0.61 | 49.0 | 4.00e-01 | 91.4% | 95.8% |
| 2ixdA00 | 3.40.50.10320 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › LmbE-like | 0.61 | 51.0 | 3.57e-01 | 94.3% | 31.0% |
| 4jgwA01 | 1.20.870.10 | Mainly Alpha › Up-down Bundle › Son of sevenless (SoS) protein; Chain S, domain 1 › Son of sevenless (SoS) protein Chain: S domain 1 | 0.59 | 50.0 | 3.94e-01 | 97.1% | 50.0% |
| 2dsjA01 | 1.20.970.10 | Mainly Alpha › Up-down Bundle › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3 › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain C | 0.58 | 48.0 | 4.92e-01 | 97.1% | 98.5% |
| 3vldA02 | 1.25.40.580 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.58 | 42.0 | 3.39e-01 | 90.0% | 36.6% |
| 3hnoA01 | 3.40.50.450 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.58 | 48.0 | 3.40e-01 | 92.9% | 38.9% |
| 2i2oA00 | 1.25.40.180 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.57 | 47.0 | 3.48e-01 | 98.6% | 44.5% |
| 8sorA01 | 1.25.10.10 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant | 0.57 | 48.0 | 3.10e-01 | 95.7% | 20.7% |
| 4eadA01 | 1.20.970.10 | Mainly Alpha › Up-down Bundle › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3 › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain C | 0.56 | 49.0 | 4.31e-01 | 100.0% | 67.3% |
| 3ckyA02 | 1.10.1040.10 | Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 | 0.56 | 44.0 | 3.59e-01 | 87.1% | 86.6% |
| 1qtwA00 | 3.20.20.150 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Divalent-metal-dependent TIM barrel enzymes | 0.56 | 47.0 | 3.16e-01 | 95.7% | 46.7% |
| 3nfqB02 | 1.20.930.10 | Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 | 0.56 | 43.0 | 3.85e-01 | 88.6% | 65.7% |
| 1hu3A00 | 1.25.40.180 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.55 | 47.0 | 3.46e-01 | 100.0% | 39.2% |
| 4ndoA00 | 3.40.1160.10 | Alpha Beta › 3-Layer(aba) Sandwich › Carbamate kinase › Acetylglutamate kinase-like | 0.54 | 45.0 | 3.16e-01 | 95.7% | 77.1% |
| 3iu5A00 | 1.20.920.10 | Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like | 0.53 | 42.0 | 3.55e-01 | 84.3% | 76.3% |
| 5ulcX00 | 1.20.920.10 | Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like | 0.53 | 41.0 | 3.42e-01 | 84.3% | 68.9% |
| 6kmjA00 | 1.20.920.10 | Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like | 0.52 | 43.0 | 3.65e-01 | 97.1% | 56.2% |
| 6cw0A00 | 1.20.920.10 | Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like | 0.52 | 41.0 | 3.58e-01 | 84.3% | 81.7% |
| 5pg1A00 | 1.20.920.10 | Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like | 0.52 | 43.0 | 3.62e-01 | 97.1% | 54.8% |
| 5uiyA00 | 1.20.920.10 | Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like | 0.52 | 42.0 | 3.68e-01 | 97.1% | 58.9% |
| 7zviA01 | 1.10.260.40 | Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains | 0.51 | 42.0 | 3.68e-01 | 98.6% | 87.7% |
| 5n13A00 | 1.20.920.10 | Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like | 0.51 | 38.0 | 3.33e-01 | 80.0% | 80.6% |
| 4dloB02 | 1.25.40.610 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.51 | 45.0 | 3.83e-01 | 100.0% | 66.7% |
ECOD (18)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4880005 | 10.2.1.16 ↗ | beta sandwiches › jelly-roll › Nucleoplasmin-like/VP (viral coat and capsid proteins) › Nucleoplasmin-like/VP (viral coat and capsid proteins) › Parvo_NS1 | 0.90 | 71.0 | 5.29e-01 | 82.9% | 36.7% |
| 3233825 | 109.4.1.70 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › CID | 0.66 | 57.0 | 4.39e-01 | 98.6% | 46.1% |
| 3986875 | 4254.1.1.1 ↗ | alpha arrays › YoaC-like › YoaC-like › YoaC-like › DUF1889 | 0.64 | 51.0 | 5.05e-01 | 87.1% | 95.9% |
| 3814731 | 109.4.1.575 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › DUF577 | 0.63 | 55.0 | 3.61e-01 | 100.0% | 42.6% |
| 3409765 | 109.4.1.32 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › MIF4G | 0.61 | 52.0 | 3.69e-01 | 100.0% | 35.2% |
| 4371241 | 181.1.1.1 ↗ | alpha bundles › Domain of the SRP/SRP receptor G proteins-like › Domain of the SRP/SRP receptor G-proteins › Domain of the SRP/SRP receptor G-proteins › SRP54_N | 0.61 | 43.0 | 3.73e-01 | 94.3% | 48.2% |
| 3199378 | 6088.1.1.1 ↗ | alpha arrays › Helical bundle domain in elongation factor 3A › Helical bundle domain in elongation factor 3A › Helical bundle domain in elongation factor 3A › 4HB | 0.60 | 46.0 | 4.25e-01 | 82.9% | 64.4% |
| 3390147 | 109.27.1.6 ↗ | alpha superhelices › Repetitive alpha hairpins › BACK domain › BACK domain › PF26017 | 0.60 | 52.0 | 4.32e-01 | 100.0% | 89.2% |
| 3632112 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.58 | 50.0 | 4.38e-01 | 95.7% | 83.8% |
| 4295547 | 195.1.1.1 ↗ | alpha complex topology › NusB-like › NusB-like › NusB-like › NusB | 0.58 | 48.0 | 3.91e-01 | 97.1% | 90.3% |
| 3200033 | 109.4.1.2268 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF28359 | 0.57 | 49.0 | 3.49e-01 | 100.0% | 52.3% |
| 3841680 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.57 | 48.0 | 3.89e-01 | 91.4% | 72.3% |
| 5061233 | 109.2.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › alpha/alpha toroid › alpha/alpha toroid | 0.57 | 50.0 | 3.10e-01 | 100.0% | 52.3% |
| 3611198 | 109.4.1.1234 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_DNAAF5 | 0.54 | 48.0 | 3.19e-01 | 100.0% | 26.9% |
| 3192679 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.54 | 46.0 | 3.50e-01 | 100.0% | 65.7% |
| 3227956 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.53 | 47.0 | 2.77e-01 | 100.0% | 15.3% |
| 3835982 | 181.1.1.1 ↗ | alpha bundles › Domain of the SRP/SRP receptor G proteins-like › Domain of the SRP/SRP receptor G-proteins › Domain of the SRP/SRP receptor G-proteins › SRP54_N | 0.52 | 41.0 | 3.69e-01 | 97.1% | 62.1% |
| 5005176 | 604.15.1.0 ↗ | alpha bundles › Spectrin repeat-like › Efb C-domain-like › Efb C-domain-like | 0.52 | 39.0 | 4.06e-01 | 85.7% | 92.3% |