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replicase

Euk-Vir

Changjiang_sobemo-like_virus_2

replicase__YP_009337124__Changjiang_sobemo-like_virus_2__1922801

Identity

Accession:
YP_009337124 ↗
Protein ID:
replicase
Kingdom:
euk

Quality

57.2 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 1122-1189
PDB
Domain cluster: representative
CATH (35)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1ciyA01 1.20.190.10 Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › Pesticidal crystal protein, N-terminal domain 0.73 58.0 4.05e-01 86.8% 55.2%
4jgwA01 1.20.870.10 Mainly Alpha › Up-down Bundle › Son of sevenless (SoS) protein; Chain S, domain 1 › Son of sevenless (SoS) protein Chain: S domain 1 0.71 60.0 4.69e-01 97.1% 84.0%
2a9uA01 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.71 54.0 4.35e-01 80.9% 62.7%
4jxtA00 1.25.40.90 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.70 58.0 4.71e-01 92.6% 88.5%
3bjdA01 1.10.1240.20 Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Lytic transglycosylase, superhelical linker domain 0.68 54.0 5.04e-01 89.7% 88.6%
2i2oA00 1.25.40.180 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.67 58.0 4.16e-01 100.0% 43.6%
1yz5B00 1.20.190.20 Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › 14-3-3 domain 0.67 59.0 4.09e-01 100.0% 36.7%
1dd5A01 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.66 51.0 4.38e-01 83.8% 89.0%
3efzB00 1.20.190.20 Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › 14-3-3 domain 0.66 56.0 4.01e-01 100.0% 39.1%
2zcxA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.65 57.0 4.09e-01 100.0% 59.0%
2wzkA03 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.65 51.0 4.37e-01 86.8% 91.8%
3wdoA01 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.64 48.0 3.01e-01 80.9% 37.0%
1x9fC00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.64 48.0 3.77e-01 80.9% 49.0%
1sxjB03 1.20.272.10 Mainly Alpha › Up-down Bundle › Zinc Finger, Delta Prime; domain 3 › 0.64 44.0 4.02e-01 72.1% 76.1%
7wf8B01 1.10.167.10 Mainly Alpha › Orthogonal Bundle › Regulator of G-protein Signalling 4; domain 2 › Regulator of G-protein Signalling 4, domain 2 0.64 50.0 4.10e-01 83.8% 65.3%
1d9cA00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.64 49.0 4.13e-01 85.3% 67.8%
4dlqA02 1.25.40.610 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.63 54.0 4.91e-01 100.0% 88.4%
3oxfA05 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.63 53.0 5.20e-01 95.6% 94.7%
3qkyA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.62 53.0 3.72e-01 100.0% 46.2%
4nqwB00 1.10.10.1320 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Anti-sigma factor, zinc-finger domain 0.61 44.0 4.40e-01 82.4% 74.0%
4adnA01 1.20.1280.250 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.60 44.0 4.12e-01 77.9% 67.1%
5mdtA00 1.25.40.90 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.60 51.0 4.07e-01 100.0% 68.4%
2d6yA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.60 51.0 3.86e-01 100.0% 65.1%
3zq5A03 3.30.450.270 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PHY domain 0.60 46.0 3.67e-01 86.8% 95.4%
6wv5A01 1.20.1440.130 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › VKOR domain 0.60 47.0 3.77e-01 85.3% 55.1%
2fx0A02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.60 45.0 3.75e-01 85.3% 62.1%
4iluA02 1.20.58.1290 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › CarD-like, C-terminal domain 0.59 47.0 4.06e-01 89.7% 65.8%
2yguC00 1.10.238.190 Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › 0.59 40.0 3.40e-01 72.1% 76.3%
2b8iA00 1.20.1280.100 Mainly Alpha › Up-down Bundle › Monooxygenase › Pas factor, saposin domain 0.59 44.0 4.24e-01 82.4% 71.4%
3dewA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.57 43.0 3.55e-01 86.8% 63.6%
2dg8D00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.56 42.0 3.24e-01 82.4% 43.4%
1kblA05 1.20.80.30 Mainly Alpha › Up-down Bundle › Acyl-CoA Binding Protein › 0.55 40.0 3.74e-01 97.1% 60.7%
3h0dB02 1.10.1200.150 Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › Transcriptional repressor of class III stress genes, C-terminal domain 0.53 37.0 3.54e-01 73.5% 69.1%
2o7tA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.52 40.0 3.04e-01 88.2% 55.7%
1o6cB01 3.40.50.2000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; 0.50 43.0 3.10e-01 98.5% 46.1%
ECOD (31)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3807750 186.2.1.1 alpha arrays › lambda integrase-N-like › VEFS domain › VEFS domain › VEFS-Box 0.74 62.0 5.15e-01 95.6% 74.4%
3785501 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.73 65.0 3.85e-01 100.0% 14.3%
4397328 604.10.1.1 alpha bundles › Spectrin repeat-like › Enzyme IIa from lactose specific PTS, IIa-lac › Enzyme IIa from lactose specific PTS, IIa-lac › PTS_IIA 0.71 55.0 4.75e-01 86.8% 81.8%
4623297 109.4.1.70 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › CID 0.70 60.0 4.91e-01 100.0% 83.7%
4027756 109.4.1.22 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Adaptin_N 0.70 60.0 3.95e-01 100.0% 44.3%
3219077 109.6.1.1 alpha superhelices › Repetitive alpha hairpins › Ras GEF › Ras GEF › RasGEF 0.69 60.0 3.65e-01 94.1% 36.3%
3620516 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.68 58.0 4.99e-01 97.1% 65.5%
4936366 3997.1.1.1 alpha arrays › Helical insertion domain in magnesium chelatase catalytic subunit › Helical insertion domain in magnesium chelatase catalytic subunit › Helical insertion domain in magnesium chelatase catalytic subunit › CobN-Mg_chel 0.68 53.0 3.80e-01 83.8% 61.5%
3294636 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.67 52.0 4.36e-01 82.4% 93.0%
3475614 186.2.1.1 alpha arrays › lambda integrase-N-like › VEFS domain › VEFS domain › VEFS-Box 0.66 56.0 4.64e-01 98.5% 55.4%
4401167 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.65 54.0 4.47e-01 92.6% 51.2%
3301417 109.4.1.70 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › CID 0.65 54.0 4.64e-01 95.6% 74.8%
3618145 109.4.1.32 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › MIF4G 0.64 54.0 3.67e-01 98.5% 48.0%
4218930 181.1.1.1 alpha bundles › Domain of the SRP/SRP receptor G proteins-like › Domain of the SRP/SRP receptor G-proteins › Domain of the SRP/SRP receptor G-proteins › SRP54_N 0.63 44.0 4.27e-01 72.1% 72.0%
3576407 622.4.1.0 alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related 0.63 49.0 4.16e-01 85.3% 92.2%
4099504 604.17.1.0 alpha bundles › Spectrin repeat-like › MTH_863 C-terminal domain-like › MTH_863 C-terminal domain-like 0.63 47.0 4.88e-01 82.4% 95.0%
3486453 310.2.1.0 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF 0.63 48.0 4.29e-01 86.8% 88.6%
4160833 109.4.1.19 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Vitellogenin_N 0.62 53.0 3.40e-01 100.0% 45.9%
3990660 610.2.1.0 alpha arrays › ERP29 C domain-like › Helical domain of Sec23/24 › Helical domain of Sec23/24 0.62 52.0 4.65e-01 100.0% 81.0%
3218670 109.4.1.202 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_16 0.61 53.0 3.79e-01 100.0% 44.2%
3518320 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.61 47.0 4.14e-01 88.2% 83.6%
3189192 109.4.1.510 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HbrB 0.60 45.0 3.08e-01 80.9% 36.3%
3480193 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.60 45.0 2.93e-01 85.3% 40.8%
5046243 106.1.1.2 alpha arrays › Globin-like › Globin-like › Globin-like › Phycobilisome 0.58 45.0 3.84e-01 86.8% 61.7%
4590160 3455.1.1.0 alpha arrays › WY-domain in RXLR effectors › WY-domain in RXLR effectors › WY-domain in RXLR effectors 0.58 45.0 4.19e-01 86.8% 82.2%
3736050 109.4.1.510 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HbrB 0.58 49.0 3.47e-01 98.5% 63.5%
3714518 226.1.1.0 a+b two layers › POZ domain › POZ domain › POZ domain 0.57 46.0 3.52e-01 94.1% 57.7%
4928534 191.1.1.63 alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › TetR_N 0.57 50.0 3.67e-01 100.0% 77.8%
4200532 132.1.1.0 alpha bundles › ACP-like › Acyl-carrier protein (ACP) › Acyl-carrier protein (ACP) 0.53 36.0 3.41e-01 98.5% 57.6%
3958387 1075.5.1.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter 0.52 39.0 3.06e-01 85.3% 86.5%
3937363 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.52 43.0 3.51e-01 97.1% 90.0%
D2 medium residues 296-382
PDB
D3 medium residues 420-520_600-612
PDB
D4 medium residues 521-599
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02122.22 best Peptidase_S39 25.1 1.70e-05 96.2% 21.7%
CATH (58)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2as9B01 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.89 76.0 6.86e-01 100.0% 69.3%
1wczA01 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.85 79.0 6.77e-01 100.0% 67.0%
1zyoA01 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.85 75.0 6.80e-01 100.0% 73.3%
4ri0A01 2.40.10.120 Mainly Beta › Beta Barrel › Thrombin, subunit H › 0.84 74.0 5.35e-01 100.0% 37.4%
3k6yA02 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.84 78.0 6.96e-01 100.0% 84.1%
2w5eA02 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.84 65.0 6.75e-01 96.2% 87.8%
2rceA02 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.83 78.0 6.99e-01 100.0% 80.2%
3otpA01 2.40.10.120 Mainly Beta › Beta Barrel › Thrombin, subunit H › 0.83 78.0 5.60e-01 100.0% 43.8%
1dleB02 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.83 76.0 6.18e-01 100.0% 97.9%
1p3cA01 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.82 77.0 6.90e-01 100.0% 77.1%
5hmaA02 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.82 76.0 6.83e-01 100.0% 82.7%
4ic5A02 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.80 75.0 6.77e-01 100.0% 79.8%
1agjA01 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.80 74.0 6.10e-01 100.0% 61.2%
3l6pA02 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.78 67.0 6.09e-01 100.0% 70.5%
1boqA02 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.78 72.0 6.46e-01 100.0% 85.0%
1havB02 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.77 70.0 6.41e-01 100.0% 94.2%
1lvbA01 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.76 69.0 6.18e-01 100.0% 73.1%
2bhgA02 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.75 69.0 6.31e-01 100.0% 80.4%
1hpgA02 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.75 69.0 6.40e-01 100.0% 82.8%
2ol5A00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.71 64.0 4.87e-01 100.0% 74.3%
3cp3A00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.71 64.0 5.44e-01 100.0% 83.5%
2xzlA02 2.40.30.230 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › 0.71 49.0 4.94e-01 72.2% 73.4%
1ylnA01 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.70 63.0 5.57e-01 100.0% 83.3%
3ec6A00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.70 62.0 5.34e-01 100.0% 85.2%
1a1rA02 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.70 61.0 5.93e-01 100.0% 87.1%
4ybnB00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.69 62.0 4.57e-01 100.0% 63.9%
3u5wA00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.68 61.0 5.22e-01 100.0% 84.1%
5jv4A00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.68 61.0 5.02e-01 100.0% 89.4%
2hq9B00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.68 60.0 5.05e-01 100.0% 85.4%
3cp7A01 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.68 59.0 5.23e-01 94.9% 83.8%
1yoaA00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.67 57.0 4.56e-01 94.9% 76.7%
1i0rA00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.67 56.0 4.53e-01 94.9% 76.4%
4l82A00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.67 56.0 4.57e-01 94.9% 76.3%
2ptfA01 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.67 58.0 4.81e-01 100.0% 83.0%
3b5mA01 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.67 56.0 4.94e-01 94.9% 91.6%
3bnkA00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.66 56.0 4.29e-01 94.9% 65.6%
1mrzB02 2.40.30.30 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Riboflavin kinase-like 0.66 43.0 3.85e-01 74.7% 47.3%
2o8lA02 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.65 57.0 5.27e-01 96.2% 82.2%
6j0qA02 2.40.30.120 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Positive stranded ssRNA viruses 0.64 45.0 4.09e-01 74.7% 56.9%
4lduA03 2.30.30.1040 Mainly Beta › Roll › SH3 type barrels. › 0.61 45.0 4.82e-01 98.7% 91.2%
3lkmA01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.61 48.0 3.85e-01 86.1% 100.0%
3p06A00 3.30.230.110 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S5; domain 2 › 0.60 42.0 3.23e-01 74.7% 61.9%
4ecnA01 2.60.40.3540 Mainly Beta › Sandwich › Immunoglobulin-like › Domain of unknown function DUF4458 0.59 52.0 4.78e-01 100.0% 85.4%
1zq1A01 2.30.30.520 Mainly Beta › Roll › SH3 type barrels. › 0.57 40.0 4.09e-01 74.7% 81.8%
2p5zX01 2.30.110.50 Mainly Beta › Roll › Pnp Oxidase; Chain A › 0.57 47.0 3.72e-01 92.4% 51.2%
2fwvA00 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.56 40.0 3.05e-01 74.7% 75.8%
6euaA01 3.90.215.10 Alpha Beta › Alpha-Beta Complex › Gamma Fibrinogen; Chain A, domain 1 › Gamma Fibrinogen, chain A, domain 1 0.56 38.0 3.23e-01 74.7% 40.3%
2xk0A00 2.30.30.140 Mainly Beta › Roll › SH3 type barrels. › 0.56 38.0 4.07e-01 79.7% 81.2%
4iupA02 2.30.30.140 Mainly Beta › Roll › SH3 type barrels. › 0.56 40.0 4.17e-01 74.7% 93.1%
2dpyA00 3.40.50.12240 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.56 48.0 2.98e-01 93.7% 55.7%
2h6oA01 2.60.40.2800 Mainly Beta › Sandwich › Immunoglobulin-like › 0.55 44.0 3.60e-01 87.3% 81.2%
4kujA01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.55 42.0 3.53e-01 86.1% 100.0%
5iu1B00 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.54 34.0 3.10e-01 73.4% 44.6%
2vrsA03 2.60.90.40 Mainly Beta › Sandwich › Adenovirus Type 5 Fiber Protein (Receptor Binding Domain) › 0.54 47.0 4.03e-01 98.7% 97.7%
3ai4A00 2.40.155.10 Mainly Beta › Beta Barrel › Green Fluorescent Protein › Green fluorescent protein 0.53 46.0 3.29e-01 100.0% 85.5%
2f5tX02 2.30.30.690 Mainly Beta › Roll › SH3 type barrels. › 0.52 37.0 3.57e-01 74.7% 84.4%
2vgmA01 2.30.30.870 Mainly Beta › Roll › SH3 type barrels. › Pelota, domain A 0.51 36.0 3.19e-01 74.7% 63.1%
3bk5A00 2.50.20.10 Mainly Beta › Clam › outer membrane lipoprotein receptor (LolB), chain A › Lipoprotein localisation LolA/LolB/LppX 0.51 43.0 3.10e-01 93.7% 92.8%
ECOD (77)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3672433 1.1.5.33 beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Trypsin_2 0.87 80.0 5.25e-01 100.0% 26.6%
4683578 1.1.5.33 beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Trypsin_2 0.86 81.0 5.65e-01 100.0% 40.0%
None 0.86 79.0 5.56e-01 100.0% 35.5%
3425181 1.1.17.3 beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin_2 0.86 77.0 5.31e-01 100.0% 32.6%
None 0.86 79.0 5.57e-01 100.0% 36.2%
4166426 1.1.5.33 beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Trypsin_2 0.85 80.0 5.38e-01 100.0% 33.2%
3443107 1.1.17.3 beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin_2 0.85 78.0 5.47e-01 100.0% 34.2%
1096110 1.1.17.3 beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin_2 0.85 79.0 5.53e-01 100.0% 35.6%
4453816 1.1.5.33 beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Trypsin_2 0.85 80.0 5.27e-01 100.0% 40.0%
3433009 1.1.17.3 beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin_2 0.85 79.0 5.34e-01 100.0% 30.6%
None 0.85 79.0 5.52e-01 100.0% 35.8%
3448643 1.1.5.0 beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 0.85 79.0 5.68e-01 100.0% 42.0%
140973 1.1.17.3 beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin_2 0.84 78.0 5.47e-01 100.0% 39.6%
3436414 1.1.17.3 beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin_2 0.84 76.0 5.42e-01 100.0% 36.7%
3449628 1.1.5.33 beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Trypsin_2 0.84 75.0 6.56e-01 100.0% 67.0%
4329871 1.1.5.33 beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Trypsin_2 0.84 78.0 5.73e-01 100.0% 42.1%
3447254 1.1.5.33 beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Trypsin_2 0.83 75.0 5.33e-01 100.0% 35.0%
3367044 1.1.17.3 beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin_2 0.83 78.0 5.25e-01 100.0% 34.6%
3415399 1.1.5.33 beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Trypsin_2 0.83 78.0 5.52e-01 100.0% 40.5%
3962616 1.1.5.33 beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Trypsin_2 0.83 78.0 5.90e-01 100.0% 52.9%
5072499 1.1.17.3 beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin_2 0.83 77.0 5.61e-01 100.0% 42.5%
5063188 1.1.5.33 beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Trypsin_2 0.83 76.0 5.38e-01 100.0% 35.8%
3663381 1.1.5.33 beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Trypsin_2 0.83 78.0 5.12e-01 100.0% 31.1%
3956586 1.1.17.3 beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin_2 0.83 78.0 5.35e-01 100.0% 40.0%
3462061 1.1.5.0 beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 0.83 75.0 5.33e-01 100.0% 35.8%
2512790 1.1.5.33 beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Trypsin_2 0.83 73.0 5.04e-01 100.0% 31.1%
4031177 1.1.5.33 beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Trypsin_2 0.83 78.0 5.50e-01 100.0% 37.9%
4338510 1.1.5.33 beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Trypsin_2 0.82 76.0 5.43e-01 100.0% 40.5%
None 0.82 78.0 5.52e-01 100.0% 38.6%
4387060 1.1.17.1 beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.82 78.0 5.48e-01 100.0% 37.7%
3428120 1.1.5.33 beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Trypsin_2 0.82 76.0 5.04e-01 100.0% 31.0%
4822902 1.1.17.3 beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin_2 0.82 76.0 5.93e-01 100.0% 50.0%
4625374 1.1.5.33 beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Trypsin_2 0.82 76.0 5.33e-01 100.0% 38.7%
5063379 1.1.17.3 beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin_2 0.82 77.0 5.72e-01 100.0% 43.9%
4647114 1.1.5.33 beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Trypsin_2 0.82 76.0 5.27e-01 100.0% 37.1%
3428386 1.1.17.3 beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin_2 0.82 75.0 5.13e-01 100.0% 31.2%
4247805 1.1.5.1 beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Trypsin 0.82 77.0 5.47e-01 100.0% 38.4%
3417330 1.1.17.0 beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 0.81 72.0 5.17e-01 100.0% 35.3%
3448847 1.1.17.3 beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin_2 0.81 76.0 5.05e-01 100.0% 31.6%
3989070 1.1.17.1 beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.81 74.0 5.24e-01 100.0% 35.8%
5039871 1.1.5.0 beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 0.78 72.0 4.92e-01 100.0% 34.2%
3907927 1.1.5.1 beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Trypsin 0.78 63.0 6.20e-01 86.1% 87.1%
3654499 1.1.5.33 beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Trypsin_2 0.78 72.0 6.07e-01 100.0% 72.0%
3883172 1.1.5.33 beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Trypsin_2 0.77 63.0 5.86e-01 86.1% 77.9%
4930890 1.1.7.0 beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C 0.77 52.0 5.38e-01 74.7% 73.3%
5035938 1.1.17.0 beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 0.77 72.0 5.04e-01 100.0% 39.1%
2137682 1.1.5.32 beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › PilZNR 0.75 69.0 6.32e-01 100.0% 86.3%
4059005 1.1.17.23 beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Peptidase_S7 0.75 68.0 4.67e-01 100.0% 45.0%
257 1.1.5.3 beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Peptidase_C4 0.74 68.0 4.87e-01 100.0% 36.5%
4319764 1.1.7.17 beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › ATP-synt_ab_N 0.74 51.0 4.58e-01 77.2% 51.8%
4019128 1.1.5.8 beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Putative_PNPOx 0.73 64.0 4.89e-01 100.0% 82.6%
1790393 1.1.7.0 beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C 0.71 49.0 4.85e-01 75.9% 68.3%
5065295 1.1.5.17 beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › DUF447_N 0.71 61.0 4.96e-01 100.0% 85.0%
3674829 1.1.13.61 beta barrels › cradle loop barrel › RIFT-related › Phage tail proteins › Gar1 0.69 57.0 6.03e-01 98.7% 100.0%
5067070 1.1.5.17 beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › DUF447_N 0.69 61.0 5.08e-01 100.0% 91.4%
4013582 1.1.5.0 beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 0.68 58.0 4.74e-01 93.7% 67.6%
3598250 206.1.1.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase 0.61 51.0 3.56e-01 91.1% 58.8%
1680295 206.1.1.13 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Alpha_kinase 0.61 48.0 3.35e-01 86.1% 60.9%
3847699 206.1.1.13 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Alpha_kinase 0.60 48.0 3.26e-01 87.3% 43.8%
3710913 4.1.1.0 beta barrels › SH3 › SH3 › SH3 0.60 43.0 3.75e-01 74.7% 71.7%
3834563 4.1.1.42 beta barrels › SH3 › SH3 › SH3 › Agenet 0.59 42.0 4.25e-01 74.7% 83.7%
5013673 219.1.1.0 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases 0.58 43.0 3.40e-01 81.0% 50.0%
3559960 2006.1.6.66 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › DUF4537 0.57 41.0 4.28e-01 74.7% 88.6%
4071824 4.17.1.1 beta barrels › SH3 › GatD N-terminal domain-like › GatD N-terminal domain-like › GatD_N 0.57 40.0 4.12e-01 74.7% 84.0%
5009312 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.57 44.0 3.94e-01 83.5% 91.8%
3855974 4.1.1.253 beta barrels › SH3 › SH3 › SH3 › DUF4537 0.57 40.0 4.13e-01 74.7% 82.7%
3254671 206.1.1.13 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Alpha_kinase 0.55 43.0 3.11e-01 87.3% 55.2%
3973504 206.1.3.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp 0.54 46.0 3.33e-01 98.7% 72.8%
3481413 206.1.1.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase 0.53 41.0 3.03e-01 88.6% 53.3%
3719860 4.1.1.0 beta barrels › SH3 › SH3 › SH3 0.53 45.0 3.99e-01 93.7% 75.7%
3836393 9.2.1.2 beta barrels › Lipocalins/Streptavidin › Avidin/Streptavidin › Avidin/Streptavidin › Vac_ImportDeg 0.52 46.0 3.48e-01 100.0% 86.3%
3258964 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.52 41.0 4.03e-01 88.6% 97.8%
3263743 9.2.1.0 beta barrels › Lipocalins/Streptavidin › Avidin/Streptavidin › Avidin/Streptavidin 0.52 40.0 3.49e-01 84.8% 82.4%
166902 71.1.1.8 beta meanders › Lipoprotein localization factors LolAB › Lipoprotein localization factors LolAB › Lipoprotein localization factors LolAB › LolA_like 0.51 43.0 3.10e-01 93.7% 92.8%
3506248 206.1.3.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp 0.51 42.0 2.88e-01 94.9% 61.3%
5058364 206.1.3.19 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › Dala_Dala_lig_C 0.51 42.0 3.19e-01 97.5% 71.2%
4944012 11.1.5.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Common fold of diphtheria toxin/transcription factors/cytochrome f 0.51 43.0 3.87e-01 94.9% 92.7%
D5 medium residues 708-776_867-892_1005-1030
PDB
Domain cluster: representative
D6 medium residues 803-866
PDB
Domain cluster: representative
CATH (1)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2i10A01 1.10.10.60 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like 0.58 38.0 3.96e-01 84.4% 71.7%
ECOD (2)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
2754394 4019.1.1.3 alpha complex topology › alpha-helical domain in beta-lactamase/transpeptidase-like proteins › alpha-helical domain in beta-lactamase/transpeptidase-like proteins › alpha-helical domain in beta-lactamase/transpeptidase-like proteins › Transpeptidase 0.54 41.0 3.56e-01 84.4% 75.7%
3424607 633.4.1.0 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor 0.50 41.0 3.19e-01 100.0% 76.0%
D7 medium residues 1064-1121
PDB
Domain cluster: representative
CATH (11)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1jkmA00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.61 48.0 3.00e-01 89.7% 45.0%
6ketA01 3.20.20.30 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Luciferase-like domain 0.58 51.0 3.17e-01 100.0% 78.8%
5x1yA02 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.57 38.0 3.06e-01 70.7% 74.6%
2hlyA00 3.10.550.10 Alpha Beta › Roll › Atu2299-like › Hypothetical protein Atu2299 0.53 40.0 2.81e-01 81.0% 48.3%
3uk7A01 3.40.50.880 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Class I glutamine amidotransferase (GATase) domain 0.53 41.0 2.91e-01 86.2% 64.2%
3iplB01 3.40.50.12780 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › ANL, N-terminal domain 0.52 40.0 2.51e-01 87.9% 17.3%
1cl8A00 3.40.580.10 Alpha Beta › 3-Layer(aba) Sandwich › ECO RI Endonuclease; Chain A › Eco RI Endonuclease, subunit A 0.52 37.0 2.45e-01 77.6% 45.2%
5xc5A00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.51 43.0 3.14e-01 96.6% 97.0%
5m1pB00 3.30.420.240 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › 0.51 41.0 3.00e-01 96.6% 79.9%
3pnnA00 3.90.550.10 Alpha Beta › Alpha-Beta Complex › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A 0.50 37.0 2.54e-01 91.4% 38.5%
1f1uA02 3.10.180.10 Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 0.50 40.0 3.09e-01 96.6% 73.6%
ECOD (17)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4468810 391.1.2.0 few secondary structure elements › Fibronectin type I module-like › Fibronectin type I module-like › VWC domain-related 0.59 35.0 2.69e-01 94.8% 26.4%
4456383 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.58 46.0 2.96e-01 91.4% 21.4%
5071704 247.1.1.1 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B 0.56 38.0 2.65e-01 72.4% 50.5%
3226732 391.1.2.0 few secondary structure elements › Fibronectin type I module-like › Fibronectin type I module-like › VWC domain-related 0.56 32.0 3.82e-01 94.8% 91.4%
4383749 2005.1.1.7 a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › tRNA-synt_1d 0.55 46.0 2.98e-01 98.3% 80.6%
4889520 2002.1.1.320 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Fas1-AflB-like_hel, DNA_pol_B_N 0.54 46.0 2.86e-01 100.0% 66.9%
3594996 2484.1.1.2 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Actin 0.53 44.0 2.94e-01 96.6% 97.3%
3708219 331.23.1.4 a+b two layers › TBP-like › Integrator IntS9/IntS11 C-terminal domain › Integrator IntS9/IntS11 C-terminal domain › CPSF100_C 0.53 32.0 3.05e-01 98.3% 47.1%
3993240 4015.1.1.1 alpha complex topology › alpha-helical domain in sec1/munc18-like (SM) proteins › alpha-helical domain in sec1/munc18-like (SM) proteins › alpha-helical domain in sec1/munc18-like (SM) proteins › Sec1 0.53 39.0 2.61e-01 86.2% 18.8%
3295308 321.1.1.7 a+b two layers › Glutamine synthetase-like › Glutamine synthetase/guanido kinase › Glutamine synthetase/guanido kinase › GCS2 0.53 40.0 2.69e-01 87.9% 68.9%
3854436 4138.1.1.1 few secondary structure elements › Granulin repeat › Granulin repeat › Granulin repeat › Granulin 0.52 27.0 3.46e-01 94.8% 96.7%
None 0.52 44.0 2.48e-01 100.0% 20.5%
4959771 2002.1.1.450 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › LAM_C 0.51 45.0 2.69e-01 100.0% 32.7%
2701382 2003.1.2.0 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain 0.51 42.0 3.38e-01 96.6% 75.2%
1680799 211.1.1.1 a+b two layers › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase 0.51 43.0 3.26e-01 100.0% 79.5%
3779769 2003.1.6.6 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › Tubulin nucleotide-binding domain-like › Misat_Tub_SegII+Tubulin_3 0.51 40.0 2.66e-01 93.1% 95.1%
None 0.50 39.0 2.51e-01 93.1% 41.1%