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replicase
Euk-VirTomato_necrotic_streak_virus
replicase__YP_009508872__Tomato_necrotic_streak_virus__1637492
Identity
- Accession:
- YP_009508872 ↗
- Protein ID:
- replicase
- Kingdom:
- euk
Quality
71.5
mean pLDDT
Taxonomy
Orthornavirae›
Kitrinoviricota›
Alsuviricetes›
Martellivirales›
Bromoviridae›
Ilarvirus›
Tomato_necrotic_streak_virus
TaxID: 1637492
Cluster
View cluster (13 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 661-740
Domain cluster:
rep: replication-associated_polyprotein_1a__YP_009165996__Privet_ringspot_virus__2169960__D691-782
CATH (8)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3vkwA01 | 3.30.450.420 | Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › | 0.70 | 62.0 | 5.01e-01 | 100.0% | 52.0% |
| 2yweA02 | 2.40.30.10 | Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Translation factors | 0.60 | 45.0 | 4.28e-01 | 82.5% | 95.0% |
| 7nkdA01 | 2.40.30.20 | Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › | 0.57 | 40.0 | 4.08e-01 | 81.2% | 75.3% |
| 3tiiA03 | 3.30.1490.20 | Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › ATP-grasp fold, A domain | 0.55 | 41.0 | 4.40e-01 | 80.0% | 100.0% |
| 2hh8A00 | 3.30.1810.10 | Alpha Beta › 2-Layer Sandwich › YdfO-like fold › YdfO-like | 0.54 | 41.0 | 3.49e-01 | 80.0% | 76.4% |
| 3kptA02 | 2.60.40.740 | Mainly Beta › Sandwich › Immunoglobulin-like › | 0.54 | 42.0 | 3.55e-01 | 86.3% | 70.2% |
| 2qkdA04 | 2.60.120.1040 | Mainly Beta › Sandwich › Jelly Rolls › ZPR1, A/B domain | 0.50 | 36.0 | 3.23e-01 | 78.8% | 78.7% |
| 7xc8A01 | 2.40.40.10 | Mainly Beta › Beta Barrel › Barwin-like endoglucanases › RlpA-like domain | 0.50 | 36.0 | 3.31e-01 | 77.5% | 99.1% |
ECOD (10)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1323359 | 3590.1.1.0 ↗ | a+b complex topology › Tomato mosaic virus helicase N-terminal domain › Tomato mosaic virus helicase N-terminal domain › Tomato mosaic virus helicase N-terminal domain | 0.71 | 57.0 | 4.69e-01 | 87.5% | 49.3% |
| 4946925 | 1.1.7.0 ↗ | beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C | 0.60 | 45.0 | 4.62e-01 | 80.0% | 100.0% |
| 3103203 | 1.1.7.35 ↗ | beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › E1_FCCH | 0.59 | 43.0 | 4.20e-01 | 78.8% | 90.0% |
| 4518161 | 1.1.7.0 ↗ | beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C | 0.59 | 46.0 | 4.28e-01 | 86.3% | 92.4% |
| 4200175 | 4261.1.1.0 ↗ | a+b two layers › TrkA C-terminal domain-like › TrkA C-terminal domain-like › TrkA C-terminal domain-like | 0.53 | 35.0 | 3.97e-01 | 77.5% | 94.8% |
| 4493756 | 11.1.1.335 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › GlgB_N | 0.52 | 36.0 | 3.50e-01 | 75.0% | 68.4% |
| 4120647 | 275.1.1.0 ↗ | a+b two layers › MoeA-I/Ornithine decarboxylase-C/Reverse ferredoxin-like domain in RNA-polymerase › MoeA-I/Ornithine decarboxylase-C/Reverse ferredoxin-like domain in RNA-polymerase › MoeA-I/Ornithine decarboxylase-C/Reverse ferredoxin-like domain in RNA-polymerase | 0.52 | 36.0 | 3.69e-01 | 72.5% | 78.7% |
| 5009921 | 217.1.1.2 ↗ | a+b complex topology › FAD-binding domain-like › FAD-binding domain › FAD-binding domain › FAD_binding_4 | 0.51 | 41.0 | 3.17e-01 | 93.8% | 74.8% |
| 4936913 | 323.1.1.1 ↗ | a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › 2-oxoacid_dh | 0.51 | 37.0 | 2.79e-01 | 81.2% | 60.4% |
| 3969578 | 3268.1.1.0 ↗ | a+b two layers › N-terminal domain in xanthine dehydrogenase › N-terminal domain in xanthine dehydrogenase › N-terminal domain in xanthine dehydrogenase | 0.51 | 26.0 | 3.10e-01 | 73.8% | 72.7% |
D2
high
residues 743-889
Domain cluster:
rep: KX578043.1__AOT27930.1__X__00015__D87-267
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF01443.25 best | Viral_helicase1 | 85.3 | 7.90e-24 | 85.7% | 47.8% |
D3
high
residues 894-1041
Domain cluster:
rep: methyltransferase-helicase__YP_009551567__Tea_plant_line_pattern_virus__2419940__D883-1037
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF01443.25 best | Viral_helicase1 | 64.2 | 2.30e-17 | 81.8% | 41.7% |
D4
medium
residues 14-48
Domain cluster:
representative
CATH (4)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4errB00 | 1.20.58.1190 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.67 | 46.0 | 3.48e-01 | 91.4% | 30.1% |
| 7p5hB03 | 1.20.1440.230 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain | 0.64 | 45.0 | 3.31e-01 | 80.0% | 29.2% |
| 3i9v104 | 1.20.1440.230 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain | 0.63 | 46.0 | 3.25e-01 | 80.0% | 28.2% |
| 2oh3A01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.62 | 48.0 | 3.19e-01 | 88.6% | 51.4% |
D5
medium
residues 92-213_276-312
Domain cluster:
rep: methyltransferase_helicase__YP_009104367__Lilac_leaf_chlorosis_virus__722755__D97-204_268-298
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF01660.23 best | Vmethyltransf | 100.1 | 1.90e-28 | 79.2% | 39.6% |
D6
medium
residues 214-275_528-545
Domain cluster:
rep: 1a_protein__NP_049331__Peanut_stunt_virus__12313__D212-238_254-285
D7
medium
residues 313-431_479-496