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replicase_polyprotein

Euk-Vir

Citrus_vein_enation_virus

replicase_polyprotein__YP_008130302__Citrus_vein_enation_virus__1301220

Identity

Accession:
YP_008130302 ↗
Protein ID:
replicase_polyprotein
Kingdom:
euk

Quality

65.1 mean pLDDT

Cluster

View cluster (38 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 210-271
PDB
D2 medium residues 380-475
PDB
Domain cluster: rep: hypothetical_protein__YP_009825042__Birds-foot_trefoil_enamovirus_1__2283314__D329-413
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02122.22 best Peptidase_S39 51.8 1.10e-13 99.0% 46.3%
CATH (32)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
6fezA02 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.85 69.0 7.03e-01 85.4% 100.0%
1zyoA02 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.84 68.0 7.31e-01 85.4% 100.0%
3f1sB02 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.72 61.0 6.18e-01 89.6% 98.9%
5hmaA01 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.71 60.0 6.32e-01 91.7% 100.0%
4yo1A01 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.70 58.0 6.07e-01 91.7% 96.6%
3nziA01 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.70 60.0 5.77e-01 91.7% 87.7%
3k6yA01 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.69 59.0 6.02e-01 91.7% 94.6%
3stjA01 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.69 52.0 5.52e-01 79.2% 95.3%
1arbA02 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.69 59.0 5.19e-01 91.7% 96.4%
4ic6C01 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.69 59.0 5.62e-01 91.7% 90.9%
1l1jA01 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.69 59.0 5.47e-01 91.7% 94.9%
4rqyA01 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.69 62.0 5.68e-01 97.9% 81.3%
2z9iC01 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.68 58.0 5.93e-01 90.6% 96.7%
3otpA01 2.40.10.120 Mainly Beta › Beta Barrel › Thrombin, subunit H › 0.67 61.0 4.74e-01 99.0% 91.1%
2sfaA01 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.62 49.0 5.08e-01 92.7% 92.3%
3su0A01 2.40.10.120 Mainly Beta › Beta Barrel › Thrombin, subunit H › 0.60 52.0 4.94e-01 91.7% 81.2%
4p0dA03 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.59 46.0 4.39e-01 83.3% 84.3%
4rt0A00 2.40.10.220 Mainly Beta › Beta Barrel › Thrombin, subunit H › predicted glycosyltransferase like domains 0.59 48.0 4.65e-01 88.5% 89.9%
1xe1A00 2.40.30.10 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Translation factors 0.58 43.0 4.45e-01 78.1% 89.0%
5i2cB01 3.30.2130.10 Alpha Beta › 2-Layer Sandwich › VC0802-like › VC0802-like 0.58 41.0 3.59e-01 74.0% 97.3%
1vw3C01 2.40.30.10 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Translation factors 0.58 40.0 3.61e-01 70.8% 58.8%
1rfeA01 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.57 44.0 4.00e-01 84.4% 81.6%
3zduA01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.57 40.0 4.43e-01 78.1% 92.1%
2i02A00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.56 43.0 3.90e-01 84.4% 78.6%
2vs7A02 3.10.28.10 Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases 0.55 39.0 4.18e-01 84.4% 89.7%
3uimA01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.55 38.0 4.02e-01 76.0% 78.7%
3irzA03 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.54 41.0 4.08e-01 81.2% 80.8%
3dtdD00 2.60.40.1880 Mainly Beta › Sandwich › Immunoglobulin-like › Invasion associated locus B (IalB) protein 0.52 43.0 3.81e-01 91.7% 95.9%
5os9A00 2.40.330.10 Mainly Beta › Beta Barrel › At1g16640 B3 domain › DNA-binding pseudobarrel domain 0.52 38.0 3.64e-01 78.1% 74.8%
4tshB01 2.60.40.740 Mainly Beta › Sandwich › Immunoglobulin-like › 0.51 42.0 3.51e-01 90.6% 76.9%
3pf2A01 2.60.40.740 Mainly Beta › Sandwich › Immunoglobulin-like › 0.50 41.0 3.43e-01 91.7% 95.4%
4fw1A02 2.30.30.10 Mainly Beta › Roll › SH3 type barrels. › Integrase, C-terminal domain superfamily, retroviral 0.50 26.0 3.26e-01 82.3% 85.2%
ECOD (27)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
2472950 1.1.5.0 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 0.86 79.0 6.22e-01 97.9% 95.1%
2710030 1.1.5.12 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Peptidase_S39 0.82 75.0 5.88e-01 99.0% 93.2%
3525486 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.74 68.0 5.06e-01 100.0% 46.1%
5063379 1.1.17.3 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin_2 0.73 64.0 5.12e-01 100.0% 50.6%
3405914 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.71 65.0 4.60e-01 100.0% 41.1%
4324118 1.1.17.3 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin_2 0.66 60.0 4.46e-01 100.0% 53.3%
3731870 1.1.17.0 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 0.66 59.0 4.08e-01 100.0% 47.9%
3727317 1.1.17.0 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 0.66 59.0 4.13e-01 99.0% 91.0%
3429385 1.1.5.0 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 0.64 57.0 4.87e-01 99.0% 98.1%
5031810 3613.1.1.0 ↗ beta barrels › Protein CLP1 C-terminal domain › Protein CLP1 C-terminal domain › Protein CLP1 C-terminal domain 0.63 35.0 3.90e-01 89.6% 69.3%
3280223 1.1.17.0 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 0.63 53.0 4.29e-01 95.8% 52.8%
4978571 1.1.5.17 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › DUF447_N 0.62 48.0 4.28e-01 84.4% 89.0%
3950458 1.1.17.0 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 0.61 52.0 4.23e-01 92.7% 95.6%
3278337 1.1.17.0 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 0.61 52.0 4.16e-01 94.8% 94.9%
4544762 11.1.4.25 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Prealbumin-like › PapC_C 0.61 43.0 4.47e-01 81.2% 79.8%
3277840 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.61 52.0 4.12e-01 95.8% 72.1%
3588234 11.1.4.36 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Prealbumin-like › SpaA 0.60 44.0 4.42e-01 81.2% 74.0%
22055 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.60 52.0 4.18e-01 95.8% 50.8%
3956786 11.1.4.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Prealbumin-like 0.57 41.0 3.90e-01 81.2% 63.5%
4959074 1.1.7.0 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C 0.56 42.0 3.93e-01 80.2% 91.7%
4951309 11.1.4.34 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Prealbumin-like › SdrD_B 0.55 42.0 3.88e-01 81.2% 76.8%
3469342 11.1.4.8 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Prealbumin-like › Pollen_Ole_e_1 0.53 41.0 4.08e-01 84.4% 85.4%
3574784 1.1.7.0 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C 0.53 39.0 3.80e-01 79.2% 83.6%
3983510 219.1.1.152 ↗ a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › PF26124 0.53 44.0 3.73e-01 92.7% 64.2%
185181 11.1.1.90 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › IalB 0.52 43.0 3.81e-01 92.7% 96.5%
3986771 101.1.2.16 ↗ alpha arrays › HTH › HTH › winged helix domain › Rep3_N 0.52 41.0 3.79e-01 88.5% 93.1%
4218945 101.1.2.16 ↗ alpha arrays › HTH › HTH › winged helix domain › Rep3_N 0.50 41.0 3.78e-01 89.6% 97.6%
D3 medium residues 476-561
PDB
Domain cluster: rep: ORF1a__YP_009047079__Human_astrovirus_BF34__1518575__D522-618
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02122.22 best Peptidase_S39 52.2 8.50e-14 97.7% 36.4%
D4 medium residues 562-629
PDB
D5 medium residues 943-1221
PDB
Domain cluster: rep: RNA-dependent_RNA-polymerase_-RdRp-__YP_004429254__Grapevine_Bulgarian_latent_virus__748667__D66-229_264-320
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02123.22 best RdRP_4 169.9 1.40e-49 97.1% 51.4%
D6 medium residues 1222-1323
PDB
Domain cluster: rep: RNA-dependent_RNA_polymerase__YP_009315896__White_clover_mottle_virus__1913024__D1098-1178
CATH (10)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1khvA05 1.20.960.20 Mainly Alpha › Up-down Bundle › Mitochondrial Import Receptor Subunit Tom20; Chain A › 0.65 45.0 4.62e-01 70.6% 82.5%
1b5lA00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.64 37.0 3.19e-01 82.4% 37.5%
1xqrA00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.58 41.0 3.04e-01 75.5% 28.1%
2lpeA01 6.10.140.1120 Special › Helix non-globular › Helix Hairpins › 0.58 33.0 3.76e-01 80.4% 74.4%
4ielA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.57 42.0 4.02e-01 76.5% 76.7%
4w4kA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.56 35.0 3.83e-01 75.5% 76.8%
5j1hA01 1.20.58.1060 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.55 47.0 3.96e-01 95.1% 90.7%
1gaxA05 1.10.287.380 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Valyl-tRNA synthetase, C-terminal domain 0.54 33.0 3.72e-01 79.4% 83.6%
2lfrA00 1.10.287.130 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain 0.54 34.0 3.36e-01 76.5% 58.6%
7zxkC01 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.51 36.0 3.16e-01 85.3% 48.7%
ECOD (4)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3293917 616.1.1.28 ↗ alpha arrays › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › RNA_pol_Rpb1_1 0.67 37.0 3.53e-01 76.5% 45.8%
3238086 109.3.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.56 41.0 3.15e-01 78.4% 60.0%
3633123 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.51 37.0 3.60e-01 76.5% 93.0%
4349635 141.1.1.0 ↗ alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases 0.50 39.0 2.91e-01 86.3% 51.7%