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replicase_protein

Euk-Vir

Phaius_virus_X

replicase_protein__YP_001655010__Phaius_virus_X__457382

Identity

Accession:: YP_001655010 ↗
Protein ID:: replicase_protein
Kingdom:: euk

Quality

76.5 mean pLDDT

Taxonomy

Orthornavirae› Kitrinoviricota› Alsuviricetes› Tymovirales› Alphaflexiviridae› Potexvirus› Phaius_virus_X

TaxID: 457382

Cluster

View cluster (13 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 721-831

PDB

Domain cluster: rep: TGB1_protein__NP_619560__Garlic_latent_virus__12458__D129-228

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF01443.25 best	Viral_helicase1	59.4	6.50e-16	81.1%	38.6%

D2 medium residues 1-67

PDB

D3 medium residues 68-293_401-413

PDB

Domain cluster: rep: uncovered_polypeptide_polyprotein__YP_001086452_0-758__Chrysanthemum_virus_B__12165__D72-292

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF01660.23 best	Vmethyltransf	228.2	1.80e-67	99.6%	81.0%

D4 medium residues 294-350

PDB

Domain cluster: representative

CATH (41)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4h9nC00	1.20.58.2170	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.75	65.0	4.48e-01	100.0%	28.8%
3vkgA09	1.20.920.30	Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A ›	0.72	54.0	4.05e-01	82.5%	60.4%
3t46A00	1.20.1270.10	Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 ›	0.69	41.0	3.76e-01	91.2%	45.3%
4ragA02	1.10.10.430	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Phosphatase 2C, C-terminal domain suprefamily	0.65	52.0	5.03e-01	100.0%	79.4%
1vw4L02	1.10.246.170	Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 ›	0.65	55.0	4.91e-01	100.0%	77.6%
2vqgA00	1.10.10.1280	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Alpha-helical porin B/porin C	0.64	52.0	4.78e-01	91.2%	76.3%
3ztaA00	1.10.490.130	Mainly Alpha › Orthogonal Bundle › Globin-like ›	0.63	54.0	4.18e-01	100.0%	55.4%
3mzkB03	1.20.58.940	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.63	42.0	4.01e-01	96.5%	57.1%
5c9eB01	1.20.1280.80	Mainly Alpha › Up-down Bundle › Monooxygenase ›	0.63	53.0	4.72e-01	100.0%	83.9%
2r31A02	1.10.3580.10	Mainly Alpha › Orthogonal Bundle › ATP12-like fold › ATP12 ATPase	0.62	50.0	3.69e-01	96.5%	82.4%
3g2eB00	3.40.920.10	Alpha Beta › 3-Layer(aba) Sandwich › Pyruvate-ferredoxin Oxidoreductase; domain 3 › Pyruvate-ferredoxin oxidoreductase, PFOR, domain III	0.61	47.0	3.38e-01	87.7%	88.6%
3q1pA01	6.10.250.1120	Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces ›	0.61	36.0	4.24e-01	77.2%	87.2%
3eyyA01	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.61	49.0	4.46e-01	98.2%	65.9%
1zq3P00	1.10.10.60	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like	0.59	44.0	4.21e-01	100.0%	70.6%
2uubT00	1.20.58.110	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Ribosomal protein S20	0.59	51.0	4.30e-01	100.0%	63.6%
4nqwA02	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.59	40.0	3.88e-01	93.0%	62.5%
2k85A00	1.10.10.440	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › FF domain	0.59	46.0	4.53e-01	100.0%	86.2%
2zgyA02	3.30.420.40	Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain	0.58	40.0	3.12e-01	94.7%	30.7%
2i2xB01	1.10.1240.10	Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain	0.58	48.0	4.15e-01	100.0%	68.0%
3bf7A00	3.40.50.1820	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain	0.58	48.0	3.22e-01	100.0%	57.6%
1zhcA00	6.10.280.50	Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.58	35.0	3.25e-01	89.5%	46.1%
3e3vA03	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.57	46.0	4.70e-01	96.5%	96.4%
4ackB00	1.25.40.590	Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Type IV / VI secretion system, DotU	0.57	48.0	3.62e-01	100.0%	43.8%
3teqB00	1.10.287.3550	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.56	37.0	3.19e-01	70.2%	40.6%
3bulA01	1.10.1240.10	Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain	0.56	45.0	4.09e-01	100.0%	74.7%
6fhpD00	1.10.390.10	Mainly Alpha › Orthogonal Bundle › Neutral Protease; domain 2 › Neutral Protease Domain 2	0.56	45.0	4.41e-01	94.7%	91.9%
3b5iA02	1.10.1200.220	Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A ›	0.55	45.0	3.93e-01	94.7%	83.2%
3ddhA02	1.10.150.240	Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2	0.55	47.0	4.24e-01	100.0%	79.0%
2yy5A02	1.10.240.10	Mainly Alpha › Orthogonal Bundle › Tyrosyl-Transfer RNA Synthetase › Tyrosyl-Transfer RNA Synthetase	0.55	44.0	3.62e-01	96.5%	93.3%
1u8bA02	1.10.10.60	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like	0.54	45.0	4.43e-01	100.0%	93.4%
2lm9A00	1.20.58.970	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.54	45.0	3.91e-01	100.0%	86.5%
2pkeA02	1.10.150.240	Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2	0.53	45.0	4.12e-01	100.0%	83.3%
7xcnM01	1.10.1240.10	Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain	0.52	42.0	3.92e-01	98.2%	84.6%
5c8gB00	1.20.920.10	Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like	0.52	41.0	3.26e-01	87.7%	46.2%
3nrxA00	1.20.58.1520	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.52	43.0	3.51e-01	100.0%	73.2%
2e5zA01	1.10.10.790	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Surp module	0.51	40.0	4.06e-01	96.5%	91.5%
4it4A02	1.20.58.80	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit	0.51	45.0	3.88e-01	100.0%	72.5%
3ph0C00	1.25.40.1040	Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat ›	0.51	37.0	3.81e-01	100.0%	90.6%
2bvlA01	1.20.58.1190	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.51	41.0	3.75e-01	100.0%	89.5%
3bjdA01	1.10.1240.20	Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Lytic transglycosylase, superhelical linker domain	0.51	43.0	3.81e-01	100.0%	78.4%
3d3aA01	3.20.20.80	Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases	0.51	40.0	2.69e-01	94.7%	21.1%

ECOD (26)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3611276	4953.1.1.0 ↗	beta barrels › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like	0.70	60.0	5.10e-01	100.0%	82.0%
5014572	2.21.1.3 ↗	beta barrels › OB-fold › Small protein B (SmpB) › Small protein B (SmpB) › HTH_OrfB_IS605	0.69	59.0	4.33e-01	100.0%	35.2%
3999174	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.69	59.0	5.69e-01	100.0%	84.6%
3519277	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.68	54.0	5.35e-01	100.0%	88.3%
3520226	101.1.1.388 ↗	alpha arrays › HTH › HTH › Three-helical HTH › FLYWCH	0.68	53.0	4.25e-01	100.0%	40.8%
4380725	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.68	59.0	5.45e-01	100.0%	77.3%
3992007	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.67	54.0	5.49e-01	100.0%	98.2%
3353067	101.1.2.37 ↗	alpha arrays › HTH › HTH › winged helix domain › E2F_TDP	0.66	55.0	5.08e-01	100.0%	88.7%
3629603	283.1.1.1 ↗	a+b duplicates or obligate multimers › Creatinase/aminopeptidase-like › Creatinase/aminopeptidase › Creatinase/aminopeptidase › Peptidase_M24	0.65	57.0	3.61e-01	100.0%	32.3%
4589278	101.1.2.309 ↗	alpha arrays › HTH › HTH › winged helix domain › GPAT_C	0.64	54.0	4.55e-01	100.0%	66.7%
4963412	101.1.2.938 ↗	alpha arrays › HTH › HTH › winged helix domain › PF25947	0.63	52.0	4.68e-01	98.2%	76.5%
4927152	4049.1.1.0 ↗	alpha superhelices › alpha-helical domain in siroheme synthase middle domains-like › alpha-helical domain in siroheme synthase middle domains-like › alpha-helical domain in siroheme synthase middle domains-like	0.63	42.0	4.23e-01	70.2%	73.3%
4277031	218.1.1.2 ↗	a+b two layers › Enolase-N/ribosomal protein › Enolase N-terminal domain-like › Enolase N-terminal domain-like › Enolase_N	0.63	52.0	5.03e-01	100.0%	84.6%
3995159	197.1.1.1 ↗	alpha bundles › Acyl-CoA binding protein-like › Acyl-CoA binding protein-like › Acyl-CoA binding protein-like › FERM_M	0.63	52.0	4.27e-01	100.0%	54.8%
4130802	181.1.1.1 ↗	alpha bundles › Domain of the SRP/SRP receptor G proteins-like › Domain of the SRP/SRP receptor G-proteins › Domain of the SRP/SRP receptor G-proteins › SRP54_N	0.62	53.0	4.73e-01	100.0%	87.1%
3938196	197.1.1.0 ↗	alpha bundles › Acyl-CoA binding protein-like › Acyl-CoA binding protein-like › Acyl-CoA binding protein-like	0.61	50.0	4.13e-01	100.0%	47.5%
4124450	101.35.1.4 ↗	alpha arrays › HTH › DNA repair regulatory protein RecX › DNA repair regulatory protein RecX › RecX_HTH3	0.60	49.0	4.78e-01	100.0%	88.2%
4995419	592.2.1.0 ↗	alpha arrays › PWI domain-like › YugE-like › YugE-like	0.60	49.0	4.47e-01	100.0%	67.1%
3952621	101.35.1.0 ↗	alpha arrays › HTH › DNA repair regulatory protein RecX › DNA repair regulatory protein RecX	0.59	49.0	4.71e-01	100.0%	84.1%
2509188	563.1.1.1 ↗	alpha bundles › ATPD N-terminal domain-like › N-terminal domain of the delta subunit of the F1F0-ATP synthase › N-terminal domain of the delta subunit of the F1F0-ATP synthase › OSCP	0.59	48.0	3.97e-01	94.7%	52.6%
5057920	101.1.2.54 ↗	alpha arrays › HTH › HTH › winged helix domain › Penicillinase_R	0.59	48.0	4.38e-01	100.0%	83.5%
4206304	3455.1.1.5 ↗	alpha arrays › WY-domain in RXLR effectors › WY-domain in RXLR effectors › WY-domain in RXLR effectors › PexRD54_WY	0.58	46.0	4.14e-01	100.0%	61.2%
4107263	106.1.1.0 ↗	alpha arrays › Globin-like › Globin-like › Globin-like	0.58	49.0	3.74e-01	100.0%	57.3%
5047364	101.1.2.48 ↗	alpha arrays › HTH › HTH › winged helix domain › PadR	0.56	46.0	3.87e-01	98.2%	51.8%
3364093	148.1.3.0 ↗	alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain	0.53	44.0	4.32e-01	100.0%	93.8%
3272393	101.35.1.0 ↗	alpha arrays › HTH › DNA repair regulatory protein RecX › DNA repair regulatory protein RecX	0.52	38.0	3.65e-01	82.5%	100.0%

D5 medium residues 606-709

PDB

Domain cluster: rep: MK064563__AZI75768.1__SBFV2-gp01__00001__D223-383

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF01443.25 best	Viral_helicase1	72.2	7.90e-20	99.0%	44.3%

D6 medium residues 938-961_1084-1212

PDB

Domain cluster: rep: RNA_dependent_RNA_polymerase__YP_009091814__Yam_virus_X__1503864__D1156-1287

D7 medium residues 962-1011_1026-1083

PDB

Domain cluster: rep: RdRp__YP_006908997__Diuris_virus_A__1247115__D19-40_76-171

CATH (3)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3cexA00	1.20.120.450	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › dinb family like domain	0.57	42.0	3.61e-01	75.9%	82.9%
1bucA01	1.10.540.10	Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain	0.55	39.0	3.73e-01	72.2%	90.2%
2a7rD00	3.20.20.70	Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I	0.53	40.0	2.92e-01	80.6%	91.8%

ECOD (9)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3598902	304.48.1.0 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like	0.73	66.0	4.52e-01	100.0%	73.4%
4071235	304.48.1.0 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like	0.69	62.0	3.98e-01	100.0%	56.4%
4516798	304.48.1.0 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like	0.68	61.0	4.04e-01	100.0%	51.6%
3792091	304.48.1.25 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RRM_4	0.65	59.0	4.10e-01	100.0%	73.6%
3654976	304.48.1.1 ↗	a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1	0.61	54.0	3.84e-01	98.1%	87.0%
3602060	386.1.1.0 ↗	few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers	0.59	43.0	3.48e-01	75.9%	49.2%
4030041	4207.1.1.0 ↗	alpha duplicates or obligate multimers › Mediator hinge subcomplex-like › Mediator hinge subcomplex-like › RNA polymerase II holoenzyme component SRB7 (MED21)	0.53	33.0	3.09e-01	76.9%	52.3%
3954346	2006.1.6.15 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › DUF58	0.52	45.0	3.31e-01	96.3%	65.1%
4417105	2004.1.1.77 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DUF87,HerA_C	0.50	38.0	2.62e-01	80.6%	84.6%