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replicase_protein

Euk-Vir

Cnidium_virus_X

replicase_protein__YP_010087351__Cnidium_virus_X__2510428

Identity

Accession:
YP_010087351 ↗
Protein ID:
replicase_protein
Kingdom:
euk

Quality

76.2 mean pLDDT

Taxonomy

Orthornavirae› Kitrinoviricota› Alsuviricetes› Tymovirales› Alphaflexiviridae› Potexvirus› Cnidium_virus_X

TaxID: 2510428

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 67-268
PDB
Domain cluster: rep: uncovered_polypeptide_polyprotein__YP_001086452_0-758__Chrysanthemum_virus_B__12165__D72-292
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF01660.23 best Vmethyltransf 185.6 1.80e-54 100.0% 71.7%
D2 high residues 717-832
PDB
Domain cluster: rep: TGB1_protein__NP_619560__Garlic_latent_virus__12458__D129-228
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF01443.25 best Viral_helicase1 57.2 3.00e-15 80.2% 38.6%
D3 medium residues 353-411
PDB
D4 medium residues 496-526_587-652_667-712
PDB
Domain cluster: rep: MK064563__AZI75768.1__SBFV2-gp01__00001__D223-383
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF01443.25 best Viral_helicase1 60.7 2.60e-16 78.3% 52.2%
D5 medium residues 527-586_653-666
PDB
Domain cluster: rep: RNA-dependent_RNA_polymerase__YP_010087744__Euonymus_yellow_mottle_associated_virus__2586645__D587-630_739-751
CATH (5)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2debB02 3.30.559.10 Alpha Beta › 2-Layer Sandwich › Chloramphenicol Acetyltransferase › Chloramphenicol acetyltransferase-like domain 0.55 46.0 3.19e-01 98.6% 71.0%
1lq7A00 1.20.1270.70 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Designed single chain three-helix bundle 0.54 38.0 3.94e-01 94.6% 82.1%
2e5vA01 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.52 45.0 3.13e-01 100.0% 93.5%
4jvyB00 3.30.1370.10 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1 0.52 37.0 2.78e-01 75.7% 59.5%
2g2dA00 1.20.1200.10 Mainly Alpha › Up-down Bundle › Hypothetical Protein Ta1238; Chain: A; › Cobalamin adenosyltransferase-like 0.50 44.0 3.47e-01 98.6% 83.7%
ECOD (5)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3846043 219.1.1.15 ↗ a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › OTU 0.60 44.0 2.93e-01 81.1% 52.9%
4990634 181.1.1.1 ↗ alpha bundles › Domain of the SRP/SRP receptor G proteins-like › Domain of the SRP/SRP receptor G-proteins › Domain of the SRP/SRP receptor G-proteins › SRP54_N 0.57 44.0 4.20e-01 100.0% 70.0%
4148017 1.1.2.1 ↗ beta barrels › cradle loop barrel › RIFT-related › double psi › RNA_pol_Rpb2_6 0.52 40.0 2.93e-01 85.1% 40.0%
4957049 633.15.1.0 ↗ alpha bundles › Bromodomain-like › alpha-ketoacid dehydrogenase kinase-N › alpha-ketoacid dehydrogenase kinase-N 0.51 41.0 3.74e-01 91.9% 92.4%
3501178 3755.4.1.31 ↗ alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Fry_C 0.51 43.0 3.24e-01 100.0% 80.5%
D6 medium residues 867-908_935-976_1000-1037
PDB
Domain cluster: rep: RdRp__YP_006908997__Diuris_virus_A__1247115__D19-40_76-171
D7 medium residues 1056-1092_1161-1208
PDB
Domain cluster: rep: hypothetical_protein_2__YP_009337040__Changjiang_tombus-like_virus_21__1922815__D1-47_99-181
D8 medium residues 1209-1300
PDB
Domain cluster: rep: RNA_dependent_RNA_polymerase__YP_009091814__Yam_virus_X__1503864__D1288-1359
CATH (24)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2ra1A03 1.20.58.770 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.68 45.0 5.14e-01 84.8% 100.0%
4malA00 1.20.58.2200 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.66 40.0 4.80e-01 83.7% 94.9%
4dloB02 1.25.40.610 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.66 57.0 5.26e-01 94.6% 82.1%
3u8vA00 1.20.120.660 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain 0.63 42.0 4.40e-01 78.3% 75.9%
2kmfA01 1.20.58.810 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Photosystem II Pbs27 0.63 47.0 4.58e-01 80.4% 74.5%
4u7iA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.62 50.0 5.07e-01 88.0% 91.4%
4u72A01 1.20.58.480 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.61 53.0 4.10e-01 100.0% 77.9%
2b1eA02 1.20.1310.30 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › 0.61 47.0 4.01e-01 82.6% 61.6%
2hqtK00 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.61 47.0 4.43e-01 94.6% 67.5%
3uumA00 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.60 48.0 4.37e-01 87.0% 82.8%
4wqoD00 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.59 40.0 3.56e-01 70.7% 46.1%
1sr2A00 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.59 40.0 3.71e-01 88.0% 55.2%
2jbwA01 1.20.1440.110 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › acylaminoacyl peptidase 0.58 45.0 4.35e-01 82.6% 77.7%
1k8kG00 1.25.40.190 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Actin-related protein 2/3 complex subunit 5 0.58 49.0 4.35e-01 95.7% 77.7%
4g12A02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.58 50.0 4.37e-01 100.0% 75.2%
1sumB01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.55 44.0 4.27e-01 88.0% 88.8%
5jrcA00 1.20.58.2140 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.55 48.0 3.84e-01 96.7% 47.8%
4rngC00 1.20.1280.290 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.55 42.0 4.38e-01 88.0% 92.8%
1quuA01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.55 43.0 3.98e-01 88.0% 78.6%
2lseA00 1.20.120.1360 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.53 39.0 3.84e-01 100.0% 71.3%
7xcnM01 1.10.1240.10 Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain 0.53 39.0 4.16e-01 76.1% 100.0%
3bt5A00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.52 42.0 3.65e-01 90.2% 96.7%
2mabA00 1.10.10.1350 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Spidroin domain, C-terminal domain 0.51 39.0 3.76e-01 83.7% 91.7%
3c18A02 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.50 36.0 3.34e-01 75.0% 72.9%
ECOD (22)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3423217 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.68 52.0 4.22e-01 81.5% 52.4%
3488531 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.67 58.0 4.33e-01 97.8% 62.5%
3667499 109.4.1.1405 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF26524 0.66 55.0 3.37e-01 93.5% 20.2%
3995816 604.12.1.0 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.62 50.0 5.16e-01 94.6% 96.5%
3791250 601.4.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.60 44.0 3.69e-01 76.1% 68.4%
3598865 2006.1.2.0 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › DHH phosphoesterases 0.60 51.0 3.84e-01 94.6% 85.7%
3702907 2006.1.2.1 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › DHH phosphoesterases › DHH 0.59 51.0 3.83e-01 95.7% 84.8%
3212004 601.4.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.59 42.0 3.50e-01 75.0% 61.8%
3785094 604.12.1.0 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.59 48.0 4.68e-01 89.1% 86.0%
4969464 604.5.1.0 ↗ alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) 0.58 46.0 4.69e-01 87.0% 92.2%
3987421 3843.1.1.0 ↗ alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K 0.55 34.0 3.93e-01 95.7% 87.7%
5003426 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.55 47.0 4.40e-01 95.7% 82.6%
3425962 603.1.1.116 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF27980 0.55 43.0 4.42e-01 85.9% 98.8%
4527333 604.13.1.0 ↗ alpha bundles › Spectrin repeat-like › USP8 N-terminal domain-like › USP8 N-terminal domain-like 0.55 42.0 3.78e-01 84.8% 63.0%
3660443 604.6.1.40 ↗ alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › PF27980 0.53 42.0 4.24e-01 85.9% 94.4%
3583793 632.1.1.0 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain 0.53 35.0 3.13e-01 98.9% 46.9%
4304173 1075.1.1.1 ↗ alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane 0.52 45.0 3.27e-01 97.8% 73.1%
4989102 4995.1.1.1 ↗ alpha arrays › Methionine synthase domain-like › Methionine synthase domain-like › Methionine synthase domain-like › B12-binding_2 0.52 43.0 4.39e-01 93.5% 96.7%
5050707 4995.1.1.1 ↗ alpha arrays › Methionine synthase domain-like › Methionine synthase domain-like › Methionine synthase domain-like › B12-binding_2 0.52 38.0 4.09e-01 81.5% 96.0%
4947988 4995.1.1.5 ↗ alpha arrays › Methionine synthase domain-like › Methionine synthase domain-like › Methionine synthase domain-like › B12-binding 0.51 39.0 4.16e-01 85.9% 96.2%
3807769 101.1.1.0 ↗ alpha arrays › HTH › HTH › Three-helical HTH 0.51 35.0 3.60e-01 96.7% 73.3%
3545594 109.4.1.256 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Insc_C 0.51 41.0 3.87e-01 88.0% 72.7%