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replication-associated_polyprotein_2a

Euk-Vir

Privet_ringspot_virus

replication-associated_polyprotein_2a__YP_009165997__Privet_ringspot_virus__2169960

Identity

Accession:
YP_009165997 ↗
Protein ID:
replication-associated_polyprotein_2a
Kingdom:
euk

Quality

69.0 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 1-96
PDB
D2 medium residues 168-217
PDB
D3 medium residues 236-291
PDB
Domain cluster: representative
D4 medium residues 383-439_504-529
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00978.27 best RdRP_2 63.5 2.50e-17 68.7% 12.7%
CATH (2)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2b78A02 3.30.750.80 Alpha Beta › 2-Layer Sandwich › Transcription Regulator spoIIAA › RNA methyltransferase domain (HRMD) like 0.52 32.0 2.99e-01 96.4% 49.0%
3ddjA01 3.10.580.10 Alpha Beta › Roll › CBS-domain › CBS-domain 0.50 28.0 2.38e-01 98.8% 32.4%
ECOD (4)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4987009 3837.1.1.1 alpha bundles › Uncharacterized conserved protein Dip1984 › Uncharacterized conserved protein Dip1984 › Uncharacterized conserved protein Dip1984 › DUF6847 0.55 39.0 3.23e-01 73.5% 100.0%
3176065 327.11.2.32 a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) › PF29529 0.51 30.0 3.01e-01 94.0% 54.1%
3218262 5001.1.1.41 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srw 0.50 41.0 2.73e-01 90.4% 78.6%
3683773 304.114.1.0 a+b two layers › Alpha-beta plaits › Family B DNA polymerase insertion domain › Family B DNA polymerase insertion domain 0.50 35.0 3.08e-01 73.5% 66.9%
D5 medium residues 440-503_530-619
PDB
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF00978.27 best RdRP_2 100.5 1.40e-28 57.8% 18.4%
PF00978.27 RdRP_2 63.3 2.80e-17 42.2% 14.3%
D6 medium residues 620-694
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00978.27 best RdRP_2 49.1 5.80e-13 100.0% 16.6%
CATH (9)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
5hayA02 1.25.40.440 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Nucleoporin, helical domain, central subdomain 0.64 42.0 4.19e-01 98.7% 64.6%
8g0lB01 1.25.40.1040 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.61 45.0 2.88e-01 96.0% 15.5%
1mhyG02 1.20.1280.30 Mainly Alpha › Up-down Bundle › Monooxygenase › Methane monooxygenase, gamma chain, domain 2 0.60 40.0 4.10e-01 100.0% 71.2%
3b9qA01 1.20.120.140 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › SRP54, nucleotide-binding domain 0.59 38.0 3.63e-01 100.0% 55.1%
3mekA04 1.25.40.970 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.57 39.0 3.83e-01 100.0% 66.3%
4g1tA02 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.57 35.0 3.78e-01 98.7% 75.4%
1b5lA00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.56 38.0 3.11e-01 72.0% 65.8%
4malA00 1.20.58.2200 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.54 34.0 3.70e-01 96.0% 81.4%
4mhlA00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.50 39.0 3.18e-01 89.3% 56.5%
ECOD (6)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3297359 604.5.1.7 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › ALMT 0.59 49.0 4.37e-01 96.0% 80.0%
4033104 604.15.1.0 alpha bundles › Spectrin repeat-like › Efb C-domain-like › Efb C-domain-like 0.57 37.0 3.89e-01 100.0% 73.8%
3610785 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.56 49.0 3.04e-01 100.0% 18.2%
3175929 109.4.1.1318 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › N1221, DUF3402 0.53 45.0 2.77e-01 100.0% 26.0%
3190662 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.52 45.0 3.25e-01 100.0% 31.9%
3507343 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.52 39.0 3.13e-01 84.0% 68.5%