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replication-associated_polyprotein_2a
Euk-VirPrivet_ringspot_virus
replication-associated_polyprotein_2a__YP_009165997__Privet_ringspot_virus__2169960
Identity
- Accession:
- YP_009165997 ↗
- Protein ID:
- replication-associated_polyprotein_2a
- Kingdom:
- euk
Quality
69.0
mean pLDDT
Taxonomy
Orthornavirae›
Kitrinoviricota›
Alsuviricetes›
Martellivirales›
Bromoviridae›
Ilarvirus›
Privet_ringspot_virus
TaxID: 2169960
Cluster
View cluster (23 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 1-96
D2
medium
residues 168-217
D3
medium
residues 236-291
Domain cluster:
representative
D4
medium
residues 383-439_504-529
Domain cluster:
rep: hypothetical_protein_2__YP_009337432__Changjiang_tombus-like_virus_5__1922819__D23-82_137-181
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00978.27 best | RdRP_2 | 63.5 | 2.50e-17 | 68.7% | 12.7% |
CATH (2)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2b78A02 | 3.30.750.80 | Alpha Beta › 2-Layer Sandwich › Transcription Regulator spoIIAA › RNA methyltransferase domain (HRMD) like | 0.52 | 32.0 | 2.99e-01 | 96.4% | 49.0% |
| 3ddjA01 | 3.10.580.10 | Alpha Beta › Roll › CBS-domain › CBS-domain | 0.50 | 28.0 | 2.38e-01 | 98.8% | 32.4% |
ECOD (4)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4987009 | 3837.1.1.1 ↗ | alpha bundles › Uncharacterized conserved protein Dip1984 › Uncharacterized conserved protein Dip1984 › Uncharacterized conserved protein Dip1984 › DUF6847 | 0.55 | 39.0 | 3.23e-01 | 73.5% | 100.0% |
| 3176065 | 327.11.2.32 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) › PF29529 | 0.51 | 30.0 | 3.01e-01 | 94.0% | 54.1% |
| 3218262 | 5001.1.1.41 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srw | 0.50 | 41.0 | 2.73e-01 | 90.4% | 78.6% |
| 3683773 | 304.114.1.0 ↗ | a+b two layers › Alpha-beta plaits › Family B DNA polymerase insertion domain › Family B DNA polymerase insertion domain | 0.50 | 35.0 | 3.08e-01 | 73.5% | 66.9% |
D5
medium
residues 440-503_530-619
Domain cluster:
rep: hypothetical_protein_2__YP_009337040__Changjiang_tombus-like_virus_21__1922815__D1-47_99-181
Pfam (2)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00978.27 best | RdRP_2 | 100.5 | 1.40e-28 | 57.8% | 18.4% |
| PF00978.27 | RdRP_2 | 63.3 | 2.80e-17 | 42.2% | 14.3% |
D6
medium
residues 620-694
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00978.27 best | RdRP_2 | 49.1 | 5.80e-13 | 100.0% | 16.6% |
CATH (9)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5hayA02 | 1.25.40.440 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Nucleoporin, helical domain, central subdomain | 0.64 | 42.0 | 4.19e-01 | 98.7% | 64.6% |
| 8g0lB01 | 1.25.40.1040 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.61 | 45.0 | 2.88e-01 | 96.0% | 15.5% |
| 1mhyG02 | 1.20.1280.30 | Mainly Alpha › Up-down Bundle › Monooxygenase › Methane monooxygenase, gamma chain, domain 2 | 0.60 | 40.0 | 4.10e-01 | 100.0% | 71.2% |
| 3b9qA01 | 1.20.120.140 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › SRP54, nucleotide-binding domain | 0.59 | 38.0 | 3.63e-01 | 100.0% | 55.1% |
| 3mekA04 | 1.25.40.970 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.57 | 39.0 | 3.83e-01 | 100.0% | 66.3% |
| 4g1tA02 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.57 | 35.0 | 3.78e-01 | 98.7% | 75.4% |
| 1b5lA00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.56 | 38.0 | 3.11e-01 | 72.0% | 65.8% |
| 4malA00 | 1.20.58.2200 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.54 | 34.0 | 3.70e-01 | 96.0% | 81.4% |
| 4mhlA00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.50 | 39.0 | 3.18e-01 | 89.3% | 56.5% |
ECOD (6)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3297359 | 604.5.1.7 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › ALMT | 0.59 | 49.0 | 4.37e-01 | 96.0% | 80.0% |
| 4033104 | 604.15.1.0 ↗ | alpha bundles › Spectrin repeat-like › Efb C-domain-like › Efb C-domain-like | 0.57 | 37.0 | 3.89e-01 | 100.0% | 73.8% |
| 3610785 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.56 | 49.0 | 3.04e-01 | 100.0% | 18.2% |
| 3175929 | 109.4.1.1318 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › N1221, DUF3402 | 0.53 | 45.0 | 2.77e-01 | 100.0% | 26.0% |
| 3190662 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.52 | 45.0 | 3.25e-01 | 100.0% | 31.9% |
| 3507343 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.52 | 39.0 | 3.13e-01 | 84.0% | 68.5% |