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replication-associated_protein

Euk-Vir

Avon-Heathcote_Estuary_associated_circular_virus_20

replication-associated_protein__YP_009126927__Avon-Heathcote_Estuary_associated_circular_virus_20__1618244

Identity

Accession:
YP_009126927 ↗
Protein ID:
replication-associated_protein
Kingdom:
euk

Quality

73.5 mean pLDDT

Taxonomy

Shotokuvirae› Cressdnaviricota› Arfiviricetes› Cirlivirales› Circoviridae› Avon-Heathcote_Estuary_associated_circular_virus_20

TaxID: 1618244

Cluster

View cluster (114 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 165-249
PDB
D2 medium residues 3-104
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02407.23 best Viral_Rep 40.9 2.80e-10 86.3% 74.4%
CATH (82)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
6h8oA00 3.40.1310.20 Alpha Beta › 3-Layer(aba) Sandwich › Replication Protein E1; Chain: A, › 0.92 79.0 8.17e-01 100.0% 95.8%
2hw0A00 3.40.1310.20 Alpha Beta › 3-Layer(aba) Sandwich › Replication Protein E1; Chain: A, › 0.78 68.0 6.56e-01 100.0% 83.5%
2lqjA00 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.74 55.0 5.68e-01 76.5% 92.6%
3tupA02 3.30.70.380 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ferrodoxin-fold anticodon-binding domain 0.74 51.0 5.31e-01 71.6% 93.8%
1l2mA00 3.40.1310.20 Alpha Beta › 3-Layer(aba) Sandwich › Replication Protein E1; Chain: A, › 0.74 69.0 6.52e-01 100.0% 89.0%
1j2vA00 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.72 54.0 5.45e-01 78.4% 86.1%
1gh8A00 3.30.70.60 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S6/Translation elongation factor EF1B 0.71 52.0 5.55e-01 77.5% 96.6%
1pbuA00 3.30.70.1010 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Translation elongation factor EF1B, gamma chain, conserved domain 0.71 63.0 5.44e-01 99.0% 73.5%
2raqA01 3.30.70.1340 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › MTH889-like domain 0.71 52.0 5.61e-01 76.5% 92.9%
1b64A00 3.30.70.60 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S6/Translation elongation factor EF1B 0.71 53.0 5.56e-01 78.4% 95.6%
1r9wA00 3.40.1310.10 Alpha Beta › 3-Layer(aba) Sandwich › Replication Protein E1; Chain: A, › 0.71 65.0 5.85e-01 100.0% 74.6%
2x3gA00 3.30.70.1910 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.70 59.0 5.67e-01 91.2% 83.6%
2qmwA03 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.70 48.0 5.42e-01 71.6% 100.0%
4dzdA01 3.30.70.1200 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Crispr-associated protein; domain 1 0.70 44.0 5.21e-01 74.5% 94.3%
3nrbB01 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.70 50.0 5.44e-01 74.5% 97.6%
2nyiA01 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.69 51.0 5.65e-01 77.5% 98.8%
1y7pB01 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.69 49.0 5.47e-01 74.5% 97.5%
2dgxA01 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.69 48.0 5.32e-01 71.6% 100.0%
1p1lA00 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.69 51.0 5.17e-01 78.4% 87.3%
4oi3A00 3.30.70.3090 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ORF SCO4226, nickel-binding ferredoxin-like monomer 0.69 52.0 5.73e-01 79.4% 100.0%
2rrnA01 3.30.70.2040 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.68 49.0 5.37e-01 75.5% 97.6%
3n0vA01 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.68 49.0 5.35e-01 75.5% 98.8%
2v50D07 3.30.70.1440 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Multidrug efflux transporter AcrB pore domain 0.68 49.0 5.05e-01 74.5% 92.6%
3luyA03 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.68 51.0 5.45e-01 79.4% 96.6%
3o1lB01 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.68 48.0 5.17e-01 74.5% 94.3%
3ibwA00 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.68 49.0 5.45e-01 75.5% 98.7%
3c19A01 3.30.70.1380 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Transcriptional regulatory protein pf0864 domain like 0.68 50.0 5.14e-01 78.4% 85.9%
1nxiA00 3.30.70.970 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RraB-like 0.67 50.0 4.57e-01 78.4% 75.8%
2ausC02 3.30.2350.10 Alpha Beta › 2-Layer Sandwich › Pseudouridine synthase › Pseudouridine synthase 0.67 50.0 4.07e-01 79.4% 62.5%
1rtzA00 3.30.70.560 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK 0.67 55.0 4.88e-01 91.2% 100.0%
2j8aA01 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.66 47.0 5.02e-01 73.5% 100.0%
4cyuA00 3.30.70.560 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK 0.66 55.0 4.84e-01 91.2% 98.7%
3cedA00 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.66 48.0 4.90e-01 75.5% 82.7%
3s1tA02 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.66 46.0 5.09e-01 72.5% 100.0%
2bvfA03 3.40.462.20 Alpha Beta › 3-Layer(aba) Sandwich › Vanillyl-alcohol Oxidase; Chain A, domain 3 › 0.66 59.0 4.68e-01 100.0% 70.0%
3gz7B00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.66 50.0 5.09e-01 80.4% 98.0%
2dt9A02 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.65 46.0 5.04e-01 72.5% 100.0%
3mcnA01 3.30.70.560 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK 0.65 55.0 4.87e-01 93.1% 99.3%
3bdeB00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.64 47.0 4.82e-01 77.5% 98.0%
3aawA02 3.30.2130.10 Alpha Beta › 2-Layer Sandwich › VC0802-like › VC0802-like 0.63 51.0 4.37e-01 87.3% 72.1%
1a7gE00 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.63 46.0 4.97e-01 76.5% 97.6%
2pd1A01 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.63 46.0 4.79e-01 77.5% 95.8%
4hl9A00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.63 46.0 4.76e-01 76.5% 98.9%
5yppA00 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.63 50.0 5.21e-01 87.3% 97.8%
3e8oB00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.62 46.0 4.68e-01 78.4% 96.0%
3amiA02 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.62 45.0 3.70e-01 77.5% 89.9%
2qswA00 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.62 43.0 4.61e-01 72.5% 85.6%
2gffA00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.61 46.0 4.70e-01 78.4% 99.0%
2ogkD00 3.30.1440.10 Alpha Beta › 2-Layer Sandwich › 50s Ribosomal Protein L5; Chain: A, › Ribosomal protein L5 0.61 44.0 3.99e-01 75.5% 84.5%
1sqeA00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.61 47.0 4.75e-01 82.4% 99.0%
1iujA00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.61 46.0 4.62e-01 80.4% 99.0%
3v2uC02 3.30.70.3170 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.61 43.0 4.46e-01 73.5% 93.7%
2nrqA00 3.30.1440.10 Alpha Beta › 2-Layer Sandwich › 50s Ribosomal Protein L5; Chain: A, › Ribosomal protein L5 0.61 43.0 3.96e-01 74.5% 87.6%
4za1C00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.60 45.0 4.70e-01 79.4% 96.7%
2c42A03 3.40.920.10 Alpha Beta › 3-Layer(aba) Sandwich › Pyruvate-ferredoxin Oxidoreductase; domain 3 › Pyruvate-ferredoxin oxidoreductase, PFOR, domain III 0.60 38.0 3.02e-01 84.3% 30.7%
6vh5C03 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.60 48.0 5.05e-01 97.1% 97.8%
6gdxA00 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.59 53.0 5.29e-01 99.0% 93.5%
3hx9B00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.59 46.0 4.69e-01 83.3% 100.0%
5t0oA02 3.30.70.1430 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Multidrug efflux transporter AcrB pore domain 0.59 52.0 5.23e-01 97.1% 98.1%
5eokA04 3.50.4.10 Alpha Beta › 3-Layer(bba) Sandwich › Hepatocyte Growth Factor › Hepatocyte Growth Factor 0.59 39.0 4.21e-01 98.0% 81.9%
3mwbB03 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.59 50.0 5.16e-01 100.0% 98.9%
1ywhC03 2.10.60.10 Mainly Beta › Ribbon › CD59 › CD59 0.58 33.0 3.56e-01 85.3% 63.6%
2govA01 3.20.80.10 Alpha Beta › Alpha-Beta Barrel › Multidrug-efflux Transporter 1 Regulator Bmrr; Chain A › Regulatory factor, effector binding domain 0.58 50.0 4.26e-01 97.1% 78.0%
2c2nA02 3.30.70.250 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Malonyl-CoA ACP transacylase, ACP-binding 0.57 40.0 4.43e-01 73.5% 98.7%
6wl5A01 3.20.80.10 Alpha Beta › Alpha-Beta Barrel › Multidrug-efflux Transporter 1 Regulator Bmrr; Chain A › Regulatory factor, effector binding domain 0.57 48.0 4.28e-01 94.1% 83.2%
3mgjA00 3.30.70.2690 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › LOR/SDH bifunctional enzyme, conserved domain 0.56 48.0 4.94e-01 98.0% 100.0%
1d5yB03 3.20.80.10 Alpha Beta › Alpha-Beta Barrel › Multidrug-efflux Transporter 1 Regulator Bmrr; Chain A › Regulatory factor, effector binding domain 0.56 48.0 4.15e-01 97.1% 76.8%
7o4xA01 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.56 50.0 5.10e-01 98.0% 100.0%
3vteA03 3.40.462.20 Alpha Beta › 3-Layer(aba) Sandwich › Vanillyl-alcohol Oxidase; Chain A, domain 3 › 0.56 48.0 4.05e-01 99.0% 69.2%
5d79A03 3.40.462.20 Alpha Beta › 3-Layer(aba) Sandwich › Vanillyl-alcohol Oxidase; Chain A, domain 3 › 0.55 48.0 4.00e-01 99.0% 67.9%
4ud8A03 3.40.462.20 Alpha Beta › 3-Layer(aba) Sandwich › Vanillyl-alcohol Oxidase; Chain A, domain 3 › 0.55 48.0 4.02e-01 100.0% 68.5%
4exkA03 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.55 38.0 3.85e-01 72.5% 80.8%
4dn9B00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.55 46.0 4.78e-01 99.0% 99.0%
3d2uA02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.54 38.0 3.93e-01 72.5% 90.2%
2oikA00 3.30.428.10 Alpha Beta › 2-Layer Sandwich › HIT family, subunit A › HIT-like 0.54 41.0 3.72e-01 84.3% 59.0%
2n99A00 2.10.60.10 Mainly Beta › Ribbon › CD59 › CD59 0.53 34.0 3.88e-01 98.0% 88.2%
1jyhA00 3.20.80.10 Alpha Beta › Alpha-Beta Barrel › Multidrug-efflux Transporter 1 Regulator Bmrr; Chain A › Regulatory factor, effector binding domain 0.53 45.0 4.01e-01 96.1% 81.9%
1uouA03 3.90.1170.30 Alpha Beta › Alpha-Beta Complex › Aldehyde Oxidoreductase; domain 3 › Pyrimidine nucleoside phosphorylase-like, C-terminal domain 0.53 41.0 4.41e-01 93.1% 95.5%
4rx6D00 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.53 47.0 4.68e-01 100.0% 100.0%
2xdoD00 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.52 46.0 3.19e-01 99.0% 52.2%
7zhdA01 3.20.80.10 Alpha Beta › Alpha-Beta Barrel › Multidrug-efflux Transporter 1 Regulator Bmrr; Chain A › Regulatory factor, effector binding domain 0.52 43.0 3.97e-01 96.1% 81.0%
2l03A00 2.10.60.10 Mainly Beta › Ribbon › CD59 › CD59 0.51 32.0 3.59e-01 94.1% 86.5%
ECOD (96)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
2391478 304.55.1.5 ↗ a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Origin of replication-binding domains › Viral_Rep 0.92 79.0 8.17e-01 100.0% 95.8%
3621982 304.55.1.5 ↗ a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Origin of replication-binding domains › Viral_Rep 0.86 76.0 7.39e-01 100.0% 85.5%
3624100 304.55.1.0 ↗ a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Origin of replication-binding domains 0.82 56.0 6.18e-01 74.5% 84.7%
2796430 304.55.1.5 ↗ a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Origin of replication-binding domains › Viral_Rep 0.82 72.0 7.22e-01 100.0% 92.2%
4304749 304.8.1.81 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › REP_ORF2-G2P 0.80 74.0 5.37e-01 99.0% 52.3%
3270398 304.16.1.1 ↗ a+b two layers › Alpha-beta plaits › eEF-1beta-like › eEF-1beta-like › EF1_GNE 0.80 59.0 6.34e-01 77.5% 96.6%
3570963 304.16.1.1 ↗ a+b two layers › Alpha-beta plaits › eEF-1beta-like › eEF-1beta-like › EF1_GNE 0.79 58.0 5.67e-01 76.5% 79.1%
4458779 304.16.1.1 ↗ a+b two layers › Alpha-beta plaits › eEF-1beta-like › eEF-1beta-like › EF1_GNE 0.79 59.0 6.19e-01 78.4% 93.6%
2966256 304.55.1.1 ↗ a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Origin of replication-binding domains › Gemini_AL1 0.78 73.0 7.14e-01 100.0% 93.5%
4047960 304.16.1.1 ↗ a+b two layers › Alpha-beta plaits › eEF-1beta-like › eEF-1beta-like › EF1_GNE 0.78 56.0 6.12e-01 74.5% 97.6%
5073608 304.16.1.0 ↗ a+b two layers › Alpha-beta plaits › eEF-1beta-like › eEF-1beta-like 0.78 58.0 6.27e-01 78.4% 97.7%
3486397 304.16.1.0 ↗ a+b two layers › Alpha-beta plaits › eEF-1beta-like › eEF-1beta-like 0.78 58.0 6.23e-01 78.4% 98.9%
3945401 304.12.1.2 ↗ a+b two layers › Alpha-beta plaits › Ribosomal protein S6 › Ribosomal protein S6 › MgtC_SapB_C 0.77 56.0 6.10e-01 75.5% 100.0%
4218099 304.55.1.1 ↗ a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Origin of replication-binding domains › Gemini_AL1 0.77 72.0 6.47e-01 100.0% 93.3%
5038047 304.16.1.1 ↗ a+b two layers › Alpha-beta plaits › eEF-1beta-like › eEF-1beta-like › EF1_GNE 0.77 56.0 6.12e-01 75.5% 100.0%
3971355 304.12.1.2 ↗ a+b two layers › Alpha-beta plaits › Ribosomal protein S6 › Ribosomal protein S6 › MgtC_SapB_C 0.77 54.0 5.91e-01 73.5% 97.6%
3284477 304.12.1.2 ↗ a+b two layers › Alpha-beta plaits › Ribosomal protein S6 › Ribosomal protein S6 › MgtC_SapB_C 0.77 56.0 6.03e-01 75.5% 100.0%
4634052 304.16.1.1 ↗ a+b two layers › Alpha-beta plaits › eEF-1beta-like › eEF-1beta-like › EF1_GNE 0.76 57.0 6.12e-01 78.4% 98.9%
4948334 304.16.1.1 ↗ a+b two layers › Alpha-beta plaits › eEF-1beta-like › eEF-1beta-like › EF1_GNE 0.76 57.0 6.09e-01 78.4% 97.7%
330634 304.16.1.1 ↗ a+b two layers › Alpha-beta plaits › eEF-1beta-like › eEF-1beta-like › EF1_GNE 0.76 56.0 5.92e-01 77.5% 95.6%
5062146 304.16.1.1 ↗ a+b two layers › Alpha-beta plaits › eEF-1beta-like › eEF-1beta-like › EF1_GNE 0.75 54.0 5.91e-01 74.5% 98.8%
4226508 304.12.1.2 ↗ a+b two layers › Alpha-beta plaits › Ribosomal protein S6 › Ribosomal protein S6 › MgtC_SapB_C 0.75 54.0 5.91e-01 75.5% 98.8%
4403284 304.18.1.1 ↗ a+b two layers › Alpha-beta plaits › Anticodon-binding domain of PheRS › Anticodon-binding domain of PheRS › FDX-ACB 0.75 52.0 5.25e-01 70.6% 88.0%
4968326 304.16.1.1 ↗ a+b two layers › Alpha-beta plaits › eEF-1beta-like › eEF-1beta-like › EF1_GNE 0.75 54.0 5.83e-01 74.5% 97.6%
5028585 304.16.1.1 ↗ a+b two layers › Alpha-beta plaits › eEF-1beta-like › eEF-1beta-like › EF1_GNE 0.74 54.0 5.85e-01 75.5% 96.5%
148700 304.12.1.2 ↗ a+b two layers › Alpha-beta plaits › Ribosomal protein S6 › Ribosomal protein S6 › MgtC_SapB_C 0.74 55.0 5.68e-01 76.5% 92.6%
4085092 304.12.1.2 ↗ a+b two layers › Alpha-beta plaits › Ribosomal protein S6 › Ribosomal protein S6 › MgtC_SapB_C 0.74 55.0 5.70e-01 77.5% 94.7%
3937809 304.55.1.15 ↗ a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Origin of replication-binding domains › Helitron_like_N 0.74 66.0 5.39e-01 98.0% 87.8%
5026971 304.16.1.1 ↗ a+b two layers › Alpha-beta plaits › eEF-1beta-like › eEF-1beta-like › EF1_GNE 0.73 54.0 5.89e-01 77.5% 100.0%
5081005 304.16.1.1 ↗ a+b two layers › Alpha-beta plaits › eEF-1beta-like › eEF-1beta-like › EF1_GNE 0.73 53.0 5.81e-01 75.5% 100.0%
3504328 304.8.1.0 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.73 52.0 5.82e-01 74.5% 100.0%
4206173 304.8.1.2 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › ACT 0.73 53.0 5.65e-01 75.5% 90.0%
4944337 304.59.1.0 ↗ a+b two layers › Alpha-beta plaits › MTH889-like › MTH889-like 0.72 53.0 5.77e-01 77.5% 100.0%
4946218 304.4.1.0 ↗ a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.72 55.0 5.49e-01 80.4% 82.9%
3970813 304.12.1.0 ↗ a+b two layers › Alpha-beta plaits › Ribosomal protein S6 › Ribosomal protein S6 0.72 55.0 5.69e-01 80.4% 97.9%
3596967 304.46.1.0 ↗ a+b two layers › Alpha-beta plaits › eEF1-gamma domain › eEF1-gamma domain 0.72 64.0 5.54e-01 99.0% 72.2%
4947614 304.130.1.1 ↗ a+b two layers › Alpha-beta plaits › Uncharacterized protein MK0293 N-terminal domain › Uncharacterized protein MK0293 N-terminal domain › Ni_insertion 0.71 53.0 5.60e-01 78.4% 87.8%
4030594 304.46.1.1 ↗ a+b two layers › Alpha-beta plaits › eEF1-gamma domain › eEF1-gamma domain › EF1G 0.71 63.0 5.43e-01 98.0% 72.5%
3477298 304.9.1.78 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › PF28978 0.71 51.0 5.16e-01 74.5% 88.0%
5053097 304.4.1.0 ↗ a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.70 51.0 5.30e-01 76.5% 94.7%
5024788 304.59.1.1 ↗ a+b two layers › Alpha-beta plaits › MTH889-like › MTH889-like › DUF211 0.70 53.0 5.71e-01 79.4% 100.0%
3786175 304.46.1.1 ↗ a+b two layers › Alpha-beta plaits › eEF1-gamma domain › eEF1-gamma domain › EF1G 0.70 62.0 5.35e-01 99.0% 73.0%
4039920 304.130.1.1 ↗ a+b two layers › Alpha-beta plaits › Uncharacterized protein MK0293 N-terminal domain › Uncharacterized protein MK0293 N-terminal domain › Ni_insertion 0.70 52.0 5.47e-01 78.4% 88.9%
5050897 304.130.1.1 ↗ a+b two layers › Alpha-beta plaits › Uncharacterized protein MK0293 N-terminal domain › Uncharacterized protein MK0293 N-terminal domain › Ni_insertion 0.70 51.0 5.55e-01 78.4% 92.9%
4951741 304.130.1.1 ↗ a+b two layers › Alpha-beta plaits › Uncharacterized protein MK0293 N-terminal domain › Uncharacterized protein MK0293 N-terminal domain › Ni_insertion 0.69 52.0 5.47e-01 79.4% 88.9%
4988926 304.8.1.0 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.69 48.0 5.15e-01 72.5% 88.8%
3396694 304.8.1.2 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › ACT 0.69 49.0 5.21e-01 74.5% 90.0%
4956967 304.59.1.1 ↗ a+b two layers › Alpha-beta plaits › MTH889-like › MTH889-like › DUF211 0.69 51.0 5.37e-01 77.5% 87.8%
3938988 304.9.1.78 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › PF28978 0.69 51.0 5.33e-01 77.5% 94.4%
4964918 304.59.1.1 ↗ a+b two layers › Alpha-beta plaits › MTH889-like › MTH889-like › DUF211 0.69 53.0 5.57e-01 81.4% 97.8%
4030911 304.8.1.2 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › ACT 0.68 51.0 5.58e-01 79.4% 100.0%
4985889 304.8.1.2 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › ACT 0.68 47.0 5.09e-01 70.6% 90.6%
5025196 304.8.1.2 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › ACT 0.68 51.0 5.63e-01 79.4% 100.0%
5022932 304.130.1.1 ↗ a+b two layers › Alpha-beta plaits › Uncharacterized protein MK0293 N-terminal domain › Uncharacterized protein MK0293 N-terminal domain › Ni_insertion 0.68 51.0 5.53e-01 79.4% 97.6%
5000078 304.59.1.1 ↗ a+b two layers › Alpha-beta plaits › MTH889-like › MTH889-like › DUF211 0.68 52.0 5.40e-01 81.4% 91.6%
5046778 304.130.1.1 ↗ a+b two layers › Alpha-beta plaits › Uncharacterized protein MK0293 N-terminal domain › Uncharacterized protein MK0293 N-terminal domain › Ni_insertion 0.68 50.0 5.13e-01 78.4% 80.0%
None — 0.68 50.0 5.10e-01 77.5% 85.7%
3962952 304.8.1.1 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › Thr_dehydrat_C 0.68 52.0 5.31e-01 81.4% 83.0%
5004030 304.8.1.0 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.67 53.0 5.51e-01 84.3% 90.5%
4987588 304.8.1.82 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › PF27325 0.66 48.0 4.99e-01 76.5% 81.1%
5023983 304.130.1.1 ↗ a+b two layers › Alpha-beta plaits › Uncharacterized protein MK0293 N-terminal domain › Uncharacterized protein MK0293 N-terminal domain › Ni_insertion 0.66 49.0 4.98e-01 78.4% 88.0%
4407903 304.6.1.3 ↗ a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain › BBE 0.66 60.0 4.45e-01 99.0% 56.9%
3604508 304.8.1.4 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › NikR_C 0.66 49.0 5.21e-01 77.5% 96.7%
4051078 304.4.1.71 ↗ a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › DUF4937 0.66 59.0 5.67e-01 98.0% 100.0%
3285005 304.45.1.1 ↗ a+b two layers › Alpha-beta plaits › 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK › 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK › HPPK 0.66 57.0 4.87e-01 96.1% 100.0%
4112444 304.8.1.0 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.66 48.0 5.11e-01 76.5% 90.9%
3696589 304.9.1.0 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD 0.65 53.0 5.21e-01 88.2% 90.9%
3943490 304.8.1.0 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.65 46.0 5.03e-01 74.5% 96.5%
4011130 304.6.1.0 ↗ a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain 0.65 57.0 4.30e-01 99.0% 58.0%
4682347 304.6.1.3 ↗ a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain › BBE 0.64 56.0 4.19e-01 98.0% 57.0%
4015784 304.6.1.0 ↗ a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain 0.64 57.0 4.27e-01 99.0% 56.2%
3675857 304.9.1.0 ↗ a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD 0.64 49.0 4.10e-01 83.3% 48.6%
4047925 304.4.1.4 ↗ a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › ABM 0.64 48.0 4.69e-01 80.4% 99.1%
4961842 304.114.1.0 ↗ a+b two layers › Alpha-beta plaits › Family B DNA polymerase insertion domain › Family B DNA polymerase insertion domain 0.64 44.0 4.71e-01 71.6% 98.8%
4309132 304.6.1.0 ↗ a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain 0.64 55.0 4.26e-01 98.0% 60.4%
4035986 304.6.1.0 ↗ a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain 0.63 55.0 4.28e-01 99.0% 60.4%
3279556 304.6.1.5 ↗ a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain › Cytokin-bind 0.63 55.0 4.19e-01 98.0% 58.4%
4622719 304.6.1.0 ↗ a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain 0.63 56.0 4.31e-01 99.0% 62.2%
4263302 304.6.1.3 ↗ a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain › BBE 0.63 55.0 4.16e-01 99.0% 55.7%
4018691 304.6.1.3 ↗ a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain › BBE 0.62 54.0 4.12e-01 99.0% 58.1%
4403911 304.8.1.5 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › NIL 0.62 46.0 4.68e-01 78.4% 84.0%
5080366 2004.1.3.1 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › Pyruvate-ferredoxin oxidoreductase, PFOR, domain III › POR 0.62 39.0 3.28e-01 84.3% 37.1%
4994637 304.8.1.0 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.62 46.0 4.69e-01 78.4% 89.0%
5042110 882.1.1.4 ↗ a+b two layers › Ribosomal protein L5 › Ribosomal protein L5 › Ribosomal protein L5 › RNA_binding 0.62 44.0 4.03e-01 75.5% 87.9%
3291378 304.6.1.0 ↗ a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain 0.61 54.0 4.19e-01 99.0% 56.6%
3231163 390.1.1.4 ↗ few secondary structure elements › Hairpin loop containing domain-like › Hairpin loop containing domain-like › Hairpin loop containing domain-like › MANEC 0.61 41.0 4.46e-01 97.1% 83.5%
4319369 304.8.1.1 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › Thr_dehydrat_C 0.60 48.0 5.11e-01 86.3% 97.8%
3741900 210.1.3.5 ↗ a+b four layers › Ntn/PP2C › Ntn › Class II glutamine amidotransferases › GATase_7 0.60 41.0 3.07e-01 70.6% 87.3%
5048995 2484.1.1.34 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.59 48.0 3.36e-01 91.2% 96.0%
4013989 304.6.1.0 ↗ a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain 0.58 52.0 3.95e-01 100.0% 57.0%
3398289 390.1.1.8 ↗ few secondary structure elements › Hairpin loop containing domain-like › Hairpin loop containing domain-like › Hairpin loop containing domain-like › PAN_4 0.58 39.0 4.08e-01 98.0% 74.7%
4944520 304.8.1.0 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.56 46.0 3.60e-01 90.2% 85.7%
5052845 886.1.1.0 ↗ a+b duplicates or obligate multimers › Probable bacterial effector-binding domain › Probable bacterial effector-binding domain › Probable bacterial effector-binding domain 0.56 49.0 4.38e-01 98.0% 79.3%
5026422 304.8.1.0 ↗ a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.55 48.0 4.67e-01 98.0% 85.2%
4024326 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.52 36.0 3.24e-01 71.6% 84.7%
3979683 886.1.1.2 ↗ a+b duplicates or obligate multimers › Probable bacterial effector-binding domain › Probable bacterial effector-binding domain › Probable bacterial effector-binding domain › GyrI-like 0.51 44.0 3.89e-01 98.0% 78.1%
D3 medium residues 113-154
PDB
Domain cluster: representative
CATH (15)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3h20A04 1.10.1240.50 Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › 0.71 59.0 4.76e-01 100.0% 64.0%
1y0uA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.70 60.0 4.78e-01 100.0% 58.4%
2p6rA03 1.10.3380.30 Mainly Alpha › Orthogonal Bundle › Sec63 N-terminal domain-like fold › 0.69 60.0 3.80e-01 100.0% 30.3%
4fe7A03 1.10.10.60 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like 0.68 56.0 4.26e-01 100.0% 45.0%
3ulqB00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.67 58.0 5.28e-01 100.0% 81.0%
1f44A01 1.10.443.10 Mainly Alpha › Orthogonal Bundle › hpI Integrase; Chain A › Intergrase catalytic core 0.66 59.0 3.79e-01 100.0% 22.2%
1a04A02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.66 56.0 4.63e-01 100.0% 58.7%
7s03A01 1.10.10.1450 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › 0.66 54.0 5.18e-01 100.0% 92.0%
1lp1A00 1.20.5.420 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C 0.65 45.0 4.17e-01 73.8% 56.4%
1p4wA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.63 53.0 4.25e-01 97.6% 57.5%
2qgmA02 3.30.1870.10 Alpha Beta › 2-Layer Sandwich › EreA/ChaN-like, small alpha-beta sandwich › EreA-like; domain 2 0.60 49.0 4.23e-01 100.0% 59.7%
3czpB01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.59 47.0 3.00e-01 90.5% 25.8%
2q1zD01 1.10.10.1320 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Anti-sigma factor, zinc-finger domain 0.57 45.0 3.74e-01 97.6% 50.0%
3a98B01 6.10.10.90 Special › Helix non-globular › Helicase, Ruva Protein; domain 3 › 0.52 35.0 2.87e-01 71.4% 51.9%
3hjlA03 1.20.5.2020 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.51 37.0 3.76e-01 85.7% 85.4%
ECOD (9)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4332912 101.1.8.0 ↗ alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes 0.77 62.0 5.84e-01 100.0% 74.0%
3589502 101.1.1.60 ↗ alpha arrays › HTH › HTH › Three-helical HTH › HTH_23 0.72 62.0 5.86e-01 100.0% 82.0%
4173465 101.1.8.0 ↗ alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes 0.69 58.0 5.39e-01 100.0% 74.5%
4936653 4156.1.1.6 ↗ alpha arrays › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › Helicase_dom4_arc 0.68 59.0 4.09e-01 100.0% 47.6%
4942882 4156.1.1.6 ↗ alpha arrays › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › Helicase_dom4_arc 0.68 59.0 3.95e-01 100.0% 41.2%
3286659 101.1.3.1 ↗ alpha arrays › HTH › HTH › tetra-helical, LuxR-like › GerE 0.65 55.0 4.77e-01 100.0% 75.7%
3170065 210.2.1.1 ↗ a+b four layers › Ntn/PP2C › Protein serine/threonine phosphatase 2C, catalytic domain › Protein serine/threonine phosphatase 2C, catalytic domain › PP2C 0.64 54.0 3.17e-01 100.0% 15.7%
4856249 151.1.1.1 ↗ alpha bundles › Hemocyanin-N › Hemocyanin-N › Hemocyanin-N › Hemocyanin_N 0.63 49.0 4.41e-01 100.0% 65.7%
4407096 564.1.1.2 ↗ alpha arrays › N-terminal, cytoplasmic domain of anti-sigma factors › N-terminal, cytoplasmic domain of anti-sigma factors › N-terminal, cytoplasmic domain of anti-sigma factors › zf-HC2 0.55 46.0 4.14e-01 97.6% 70.0%