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replication_enhancer_protein

Euk-Vir

Tomato_leaf_curl_Barka_virus

replication_enhancer_protein__YP_009030008__Tomato_leaf_curl_Barka_virus__1498504

Identity

Accession:
YP_009030008 ↗
Protein ID:
replication_enhancer_protein
Kingdom:
euk

Quality

85.4 mean pLDDT

Taxonomy

Shotokuvirae› Cressdnaviricota› Repensiviricetes› Geplafuvirales› Geminiviridae› Begomovirus› Tomato_leaf_curl_Barka_virus

TaxID: 1498504

Cluster

View cluster (386 members)

3D Structure

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Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 1-74
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF01407.22 best Gemini_AL3 96.2 1.80e-27 98.7% 59.7%
CATH (35)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1uebA01 2.30.30.30 Mainly Beta › Roll › SH3 type barrels. › 0.70 39.0 4.21e-01 74.3% 63.5%
4ec6A00 3.10.450.540 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.70 41.0 3.57e-01 81.1% 39.4%
4kz1A00 3.10.450.230 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › VirB8 protein 0.69 44.0 3.55e-01 78.4% 34.8%
4o3vA00 3.10.450.230 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › VirB8 protein 0.68 44.0 3.58e-01 78.4% 35.5%
2gtlN02 2.40.128.620 Mainly Beta › Beta Barrel › Lipocalin › 0.67 47.0 3.59e-01 82.4% 32.4%
2gtlM02 2.40.128.620 Mainly Beta › Beta Barrel › Lipocalin › 0.66 45.0 3.52e-01 82.4% 31.9%
2gtlO02 2.40.128.620 Mainly Beta › Beta Barrel › Lipocalin › 0.66 45.0 3.53e-01 81.1% 32.5%
4wrnA02 2.60.40.3210 Mainly Beta › Sandwich › Immunoglobulin-like › Zona pellucida, ZP-N domain 0.66 50.0 4.49e-01 82.4% 97.1%
2hhiA01 3.30.565.40 Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Fervidobacterium nodosum Rt17-B1 like 0.65 46.0 3.95e-01 74.3% 75.4%
3e99A00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.65 44.0 3.52e-01 75.7% 35.1%
3bf2A00 3.30.160.150 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Lipoprotein like domain 0.65 48.0 4.10e-01 81.1% 72.0%
3ef8A00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.63 42.0 3.38e-01 75.7% 35.1%
2lyxA00 3.10.450.390 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › Protein of unknown function DUF3889 0.63 41.0 3.89e-01 86.5% 56.3%
4nzrM02 2.160.20.180 Mainly Beta › 3 Solenoid › Pectate Lyase C-like › 0.61 47.0 3.62e-01 86.5% 46.2%
8eisA01 2.70.170.10 Mainly Beta › Distorted Sandwich › Acetylcholine Binding Protein; Chain: A, › Neurotransmitter-gated ion-channel ligand-binding domain 0.61 52.0 3.83e-01 95.9% 61.5%
2cc3A00 3.10.450.230 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › VirB8 protein 0.60 39.0 3.22e-01 74.3% 34.0%
5bkaE01 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.60 43.0 3.61e-01 78.4% 43.2%
1lyvA00 3.90.190.10 Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily 0.58 47.0 3.13e-01 86.5% 28.6%
2xswB00 3.60.10.10 Alpha Beta › 4-Layer Sandwich › Deoxyribonuclease I; Chain A › Endonuclease/exonuclease/phosphatase 0.58 45.0 2.91e-01 82.4% 39.3%
6secA03 2.70.98.10 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › 0.58 45.0 3.07e-01 85.1% 83.1%
3kkgA00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.57 39.0 3.12e-01 74.3% 36.8%
1w7cA03 3.10.450.40 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.57 41.0 3.59e-01 83.8% 49.6%
5bw0F00 3.30.1300.30 Alpha Beta › 2-Layer Sandwich › Pantoate--beta-alanine Ligase; Chain: A,domain 2 › GSPII I/J protein-like 0.57 46.0 4.32e-01 89.2% 97.8%
3nqkA02 2.40.128.440 Mainly Beta › Beta Barrel › Lipocalin › Uncharacterised protein PF14274, DUF4361 0.56 48.0 3.86e-01 100.0% 88.7%
3ub1A01 3.10.450.540 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.56 41.0 3.39e-01 82.4% 43.4%
3gzrB00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.55 49.0 3.92e-01 98.6% 58.2%
2w4yA00 2.40.160.220 Mainly Beta › Beta Barrel › Porin › 0.54 41.0 3.60e-01 85.1% 68.0%
4hj1B03 2.60.40.3770 Mainly Beta › Sandwich › Immunoglobulin-like › 0.53 40.0 3.74e-01 81.1% 72.2%
4ibnA01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.53 36.0 2.78e-01 74.3% 28.7%
3d9rB00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.52 43.0 3.54e-01 89.2% 53.4%
1jkgA00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.52 44.0 3.67e-01 100.0% 51.8%
3hi7B02 3.10.450.40 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.52 39.0 3.31e-01 83.8% 47.7%
3a76A01 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.52 41.0 3.41e-01 89.2% 52.5%
3fgyA00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.51 45.0 3.70e-01 100.0% 56.3%
3hk4A00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.50 44.0 3.79e-01 100.0% 63.6%
ECOD (64)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
2390919 7579.1.1.49 ↗ a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › GCE_fung 0.72 49.0 3.03e-01 82.4% 13.3%
3696356 10.12.1.3 ↗ beta sandwiches › jelly-roll › Double-stranded beta-helix › Double-stranded beta-helix › Cupin_1 0.71 51.0 4.03e-01 75.7% 81.3%
5040130 319.1.1.0 ↗ beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones 0.70 46.0 4.36e-01 79.7% 55.6%
4098296 11.1.5.85 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Common fold of diphtheria toxin/transcription factors/cytochrome f › PFF1_C 0.70 50.0 3.83e-01 74.3% 72.5%
4020832 10.12.1.0 ↗ beta sandwiches › jelly-roll › Double-stranded beta-helix › Double-stranded beta-helix 0.70 50.0 4.22e-01 75.7% 84.0%
4987319 1036.1.1.2 ↗ a+b two layers › 60S ribosomal export protein NMD3 a+b domain › 60S ribosomal export protein NMD3 a+b domain › 60S ribosomal export protein NMD3 a+b domain › PF29994 0.69 46.0 4.05e-01 82.4% 46.4%
3817394 11.1.1.669 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › TRAPPC13_C 0.69 47.0 4.02e-01 70.3% 69.6%
861 9.3.1.3 ↗ beta barrels › Lipocalins/Streptavidin › Quinohemoprotein amine dehydrogenase A chain, domain 3-like › Quinohemoprotein amine dehydrogenase A chain, domain 3-like › Eryth_link_C 0.67 47.0 3.92e-01 82.4% 43.0%
860 9.3.1.3 ↗ beta barrels › Lipocalins/Streptavidin › Quinohemoprotein amine dehydrogenase A chain, domain 3-like › Quinohemoprotein amine dehydrogenase A chain, domain 3-like › Eryth_link_C 0.66 45.0 3.86e-01 81.1% 43.4%
4930408 243.1.1.0 ↗ a+b two layers › Cystatin-like › NTF2-like › NTF2-like 0.65 44.0 4.05e-01 91.9% 53.0%
4625357 11.1.5.85 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Common fold of diphtheria toxin/transcription factors/cytochrome f › PFF1_C 0.64 45.0 3.54e-01 73.0% 67.7%
3591628 243.3.1.0 ↗ a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin 0.64 50.0 4.31e-01 100.0% 53.9%
5056410 2484.1.1.59 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › NurA 0.64 41.0 2.69e-01 70.3% 15.2%
3405242 5084.5.1.37 ↗ beta barrels › Outer membrane meander beta-barrels › Porins › Porin › Attacin_N, Attacin_C 0.64 46.0 3.45e-01 75.7% 43.2%
3441483 5.1.3.68 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › DUF1618 0.64 45.0 2.83e-01 74.3% 15.0%
3958465 243.1.1.0 ↗ a+b two layers › Cystatin-like › NTF2-like › NTF2-like 0.63 44.0 3.49e-01 75.7% 36.0%
3732444 243.1.1.0 ↗ a+b two layers › Cystatin-like › NTF2-like › NTF2-like 0.63 42.0 3.38e-01 82.4% 35.2%
3458604 243.3.1.19 ↗ a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin › DUF3615 0.63 42.0 4.27e-01 85.1% 69.3%
4027797 922.1.1.1 ↗ few secondary structure elements › TSP-1 type 1 repeat › TSP-1 type 1 repeat › TSP-1 type 1 repeat › TSP_1 0.62 40.0 4.59e-01 74.3% 98.0%
3834272 5.1.5.96 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed › FBA_3 0.62 41.0 2.75e-01 78.4% 16.9%
5010581 310.3.1.0 ↗ a+b two layers › RRF/tRNA synthetase additional domain-like › General secretion pathway protein M (EpsM) periplasmic domain-related › General secretion pathway protein M (EpsM) periplasmic domain-related 0.62 44.0 3.75e-01 74.3% 66.1%
3724449 243.1.1.0 ↗ a+b two layers › Cystatin-like › NTF2-like › NTF2-like 0.61 45.0 4.23e-01 77.0% 63.3%
3743024 277.1.1.0 ↗ a+b two layers › PX domain › PX domain › PX domain 0.61 43.0 3.69e-01 81.1% 44.8%
3284948 2.1.1.0 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.61 43.0 4.15e-01 86.5% 64.7%
3603359 4.1.1.459 ↗ beta barrels › SH3 › SH3 › SH3 › PF29994 0.61 43.0 3.81e-01 78.4% 50.0%
3217804 922.1.1.0 ↗ few secondary structure elements › TSP-1 type 1 repeat › TSP-1 type 1 repeat › TSP-1 type 1 repeat 0.60 36.0 4.34e-01 78.4% 100.0%
3959285 243.1.1.0 ↗ a+b two layers › Cystatin-like › NTF2-like › NTF2-like 0.60 42.0 4.03e-01 77.0% 64.3%
3373981 206.1.1.0 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase 0.60 44.0 3.21e-01 89.2% 26.8%
3992476 1116.1.1.2 ↗ a+b two layers › Polycystin-mucolipin domain › Polycystin-mucolipin domain › Polycystin-mucolipin domain › MCLN_ECD 0.60 43.0 3.49e-01 77.0% 80.0%
3925468 243.3.1.0 ↗ a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin 0.59 39.0 3.60e-01 82.4% 51.0%
3608271 2003.1.5.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases 0.59 48.0 3.12e-01 90.5% 22.9%
3721678 222.1.1.15 ↗ a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › 4HBT_3C 0.59 48.0 3.49e-01 87.8% 57.9%
3972904 310.3.1.0 ↗ a+b two layers › RRF/tRNA synthetase additional domain-like › General secretion pathway protein M (EpsM) periplasmic domain-related › General secretion pathway protein M (EpsM) periplasmic domain-related 0.59 42.0 3.78e-01 74.3% 75.0%
3290399 243.1.1.0 ↗ a+b two layers › Cystatin-like › NTF2-like › NTF2-like 0.58 42.0 3.44e-01 87.8% 40.3%
3508830 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.57 50.0 4.24e-01 100.0% 97.7%
3907123 5087.2.1.2 ↗ beta meanders › Lipovitellin-phosvitin complex › Lipovitellin LV-1N › Lipovitellin LV-1N › PF29934 0.57 42.0 3.13e-01 77.0% 31.9%
3404065 295.1.1.4 ↗ a+b two layers › ssDNA-binding transcriptional regulator domain-like › ssDNA-binding transcriptional regulator domain › ssDNA-binding transcriptional regulator domain › COMM_domain 0.57 39.0 3.87e-01 77.0% 67.5%
6436 243.5.1.3 ↗ a+b two layers › Cystatin-like › Amine oxidase N-terminal region › Amine oxidase N-terminal region › DUF1965 0.57 41.0 3.33e-01 83.8% 39.0%
3961802 243.5.1.9 ↗ a+b two layers › Cystatin-like › Amine oxidase N-terminal region › Amine oxidase N-terminal region › UPF0182 0.57 40.0 2.98e-01 78.4% 27.5%
3703427 708.1.1.0 ↗ beta complex topology › ETN0001 domain-like › ETN0001 domain-like › NAC/WRKY/GCM/WOPR domain 0.57 47.0 3.99e-01 90.5% 70.0%
3941713 243.1.1.6 ↗ a+b two layers › Cystatin-like › NTF2-like › NTF2-like › VirB8 0.56 43.0 3.56e-01 87.8% 44.3%
3551920 11.1.1.640 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › ZP-N 0.56 44.0 3.97e-01 86.5% 73.3%
3253922 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.55 45.0 3.16e-01 91.9% 84.0%
3931232 2.1.1.0 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.54 38.0 3.24e-01 89.2% 44.0%
3251381 295.1.1.4 ↗ a+b two layers › ssDNA-binding transcriptional regulator domain-like › ssDNA-binding transcriptional regulator domain › ssDNA-binding transcriptional regulator domain › COMM_domain 0.54 37.0 3.89e-01 82.4% 81.5%
3962739 243.1.1.77 ↗ a+b two layers › Cystatin-like › NTF2-like › NTF2-like › PF29518 0.53 38.0 3.07e-01 81.1% 37.3%
5029179 5090.1.1.0 ↗ beta complex topology › Viral glycoprotein, central and dimerisation domains-like › Viral glycoprotein, central and dimerisation domains › Viral glycoprotein, central and dimerisation domains 0.53 37.0 3.32e-01 73.0% 53.6%
3265052 5.1.3.0 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed 0.53 33.0 2.36e-01 77.0% 19.1%
3510498 243.3.1.0 ↗ a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin 0.53 41.0 3.68e-01 82.4% 63.0%
3288890 243.1.1.0 ↗ a+b two layers › Cystatin-like › NTF2-like › NTF2-like 0.53 37.0 3.20e-01 82.4% 43.1%
3255739 295.1.1.4 ↗ a+b two layers › ssDNA-binding transcriptional regulator domain-like › ssDNA-binding transcriptional regulator domain › ssDNA-binding transcriptional regulator domain › COMM_domain 0.53 35.0 3.62e-01 75.7% 72.9%
3929299 1116.1.1.2 ↗ a+b two layers › Polycystin-mucolipin domain › Polycystin-mucolipin domain › Polycystin-mucolipin domain › MCLN_ECD 0.53 45.0 3.23e-01 97.3% 83.5%
3619356 1116.1.1.2 ↗ a+b two layers › Polycystin-mucolipin domain › Polycystin-mucolipin domain › Polycystin-mucolipin domain › MCLN_ECD 0.53 45.0 3.31e-01 97.3% 80.0%
4581478 283.2.1.16 ↗ a+b duplicates or obligate multimers › Creatinase/aminopeptidase-like › gpW/gp25-like › gpW/gp25-like › MpPF1 0.53 40.0 3.58e-01 82.4% 95.2%
3485184 5.1.4.219 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › DPPIV_N 0.52 39.0 2.36e-01 82.4% 21.0%
3223708 243.1.1.0 ↗ a+b two layers › Cystatin-like › NTF2-like › NTF2-like 0.52 45.0 3.94e-01 100.0% 62.5%
3544627 389.1.3.35 ↗ few secondary structure elements › EGF-like › EGF-related › TNF receptor-like › TSP1_spondin 0.52 37.0 4.00e-01 77.0% 93.3%
4568161 283.2.1.18 ↗ a+b duplicates or obligate multimers › Creatinase/aminopeptidase-like › gpW/gp25-like › gpW/gp25-like › Lipoprotein_17 0.52 43.0 4.22e-01 89.2% 97.5%
4118362 314.1.1.11 ↗ a+b three layers › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › tRNA_synthFbeta 0.52 41.0 3.18e-01 93.2% 89.4%
3480731 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.51 45.0 3.89e-01 100.0% 87.5%
3852438 883.1.1.24 ↗ a+b complex topology › Aha1/BPI domain-like › Aha1/BPI domain-like › Aha1/BPI domain-like › PF29321 0.51 40.0 3.15e-01 90.5% 57.8%
3201205 2003.1.5.81 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_25 0.51 45.0 2.98e-01 98.6% 88.2%
3515579 1116.1.1.2 ↗ a+b two layers › Polycystin-mucolipin domain › Polycystin-mucolipin domain › Polycystin-mucolipin domain › MCLN_ECD 0.51 43.0 3.09e-01 97.3% 85.0%
3587514 243.1.1.17 ↗ a+b two layers › Cystatin-like › NTF2-like › NTF2-like › TpcC 0.51 38.0 3.17e-01 91.9% 45.4%
D2 medium residues 75-131
PDB
Domain cluster: rep: REn__YP_009506392__Chilli_leaf_curl_Vellanad_virus_India_Vellanad_2008__1000664__D73-122
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF01407.22 best Gemini_AL3 46.9 3.30e-12 80.7% 31.1%