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reverse_transcriptase

Euk-Vir

Rose_yellow_vein_virus

reverse_transcriptase__YP_007761644__Rose_yellow_vein_virus__1213588

Identity

Accession:
YP_007761644 ↗
Protein ID:
reverse_transcriptase
Kingdom:
euk

Quality

69.4 mean pLDDT

Taxonomy

Pararnavirae› Artverviricota› Revtraviricetes› Ortervirales› Caulimoviridae› Rosadnavirus› Rose_yellow_vein_virus

TaxID: 1213588

Cluster

View cluster (17 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 185-305
PDB
Domain cluster: rep: NC_029048.2__YP_009221738.1__PHICD211_20135__00153__D2-127
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02160.20 best Peptidase_A3 36.7 4.60e-09 98.4% 55.3%
CATH (18)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1fmbA00 2.40.70.10 Mainly Beta › Beta Barrel › Cathepsin D, subunit A; domain 1 › Acid Proteases 0.81 61.0 6.52e-01 86.8% 90.4%
1a94A00 2.40.70.10 Mainly Beta › Beta Barrel › Cathepsin D, subunit A; domain 1 › Acid Proteases 0.80 58.0 6.32e-01 86.8% 89.9%
3s8iA00 2.40.70.10 Mainly Beta › Beta Barrel › Cathepsin D, subunit A; domain 1 › Acid Proteases 0.80 73.0 7.29e-01 100.0% 94.4%
3slzA00 2.40.70.10 Mainly Beta › Beta Barrel › Cathepsin D, subunit A; domain 1 › Acid Proteases 0.78 67.0 6.90e-01 99.2% 95.6%
2fivA00 2.40.70.10 Mainly Beta › Beta Barrel › Cathepsin D, subunit A; domain 1 › Acid Proteases 0.77 62.0 6.42e-01 86.8% 90.3%
3liyA00 2.40.70.10 Mainly Beta › Beta Barrel › Cathepsin D, subunit A; domain 1 › Acid Proteases 0.76 62.0 6.33e-01 86.8% 88.8%
1mvpA00 2.40.70.10 Mainly Beta › Beta Barrel › Cathepsin D, subunit A; domain 1 › Acid Proteases 0.72 56.0 5.89e-01 86.8% 88.4%
4ehcA00 2.40.70.10 Mainly Beta › Beta Barrel › Cathepsin D, subunit A; domain 1 › Acid Proteases 0.68 62.0 4.74e-01 100.0% 84.3%
1bxoA02 2.40.70.10 Mainly Beta › Beta Barrel › Cathepsin D, subunit A; domain 1 › Acid Proteases 0.67 59.0 5.42e-01 94.2% 86.8%
2pmaA01 2.40.70.10 Mainly Beta › Beta Barrel › Cathepsin D, subunit A; domain 1 › Acid Proteases 0.67 60.0 6.07e-01 98.3% 95.0%
4pphA02 2.40.70.10 Mainly Beta › Beta Barrel › Cathepsin D, subunit A; domain 1 › Acid Proteases 0.67 59.0 4.98e-01 95.0% 74.9%
1wkrA02 2.40.70.10 Mainly Beta › Beta Barrel › Cathepsin D, subunit A; domain 1 › Acid Proteases 0.66 58.0 5.14e-01 94.2% 84.7%
2vijA01 2.40.70.10 Mainly Beta › Beta Barrel › Cathepsin D, subunit A; domain 1 › Acid Proteases 0.66 57.0 5.59e-01 94.2% 100.0%
3hu1A01 2.40.40.20 Mainly Beta › Beta Barrel › Barwin-like endoglucanases › 0.65 41.0 4.54e-01 89.3% 79.2%
1miqA02 2.40.70.10 Mainly Beta › Beta Barrel › Cathepsin D, subunit A; domain 1 › Acid Proteases 0.64 55.0 5.12e-01 94.2% 87.5%
7tbdB02 2.40.70.10 Mainly Beta › Beta Barrel › Cathepsin D, subunit A; domain 1 › Acid Proteases 0.59 51.0 4.62e-01 94.2% 84.7%
2h1eA02 2.40.50.40 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › 0.52 23.0 3.13e-01 70.2% 83.6%
6cz7C02 2.40.40.20 Mainly Beta › Beta Barrel › Barwin-like endoglucanases › 0.52 43.0 4.16e-01 86.8% 97.0%
ECOD (100)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3343890 1.1.1.3 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease › RVP 0.92 63.0 7.59e-01 76.9% 100.0%
3225435 1.1.1.8 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease › gag-asp_proteas 0.90 70.0 7.29e-01 83.5% 85.8%
3370298 1.1.1.3 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease › RVP 0.89 77.0 8.10e-01 93.4% 99.1%
3334785 1.1.1.3 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease › RVP 0.88 83.0 8.14e-01 100.0% 93.1%
3337491 1.1.2.29 ↗ beta barrels › cradle loop barrel › RIFT-related › double psi › RVP 0.86 69.0 7.47e-01 85.1% 97.1%
3925981 1.1.1.8 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease › gag-asp_proteas 0.86 71.0 7.52e-01 91.7% 94.5%
3724372 1.1.1.0 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease 0.85 71.0 6.40e-01 86.0% 69.7%
3938624 1.1.1.17 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease › RVP_2 0.85 76.0 7.79e-01 100.0% 98.3%
3902845 1.1.1.30 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease › PF30863 0.85 77.0 7.49e-01 95.0% 96.2%
3529283 1.1.1.30 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease › PF30863 0.85 74.0 7.39e-01 92.6% 96.8%
3923810 1.1.1.0 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease 0.84 73.0 7.48e-01 89.3% 93.9%
3559341 1.1.1.30 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease › PF30863 0.84 76.0 7.21e-01 95.0% 87.9%
3994789 1.1.1.6 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease › Asp_protease 0.84 74.0 6.98e-01 94.2% 79.3%
3496964 1.1.1.0 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease 0.84 77.0 7.65e-01 100.0% 93.6%
3608668 1.1.1.6 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease › Asp_protease 0.84 77.0 7.09e-01 100.0% 78.0%
3883471 1.1.1.30 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease › PF30863 0.83 75.0 7.35e-01 95.0% 97.7%
3436417 1.1.1.17 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease › RVP_2 0.83 79.0 7.72e-01 100.0% 94.6%
3878578 1.1.1.30 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease › PF30863 0.83 75.0 7.47e-01 95.0% 96.8%
3421072 1.1.1.30 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease › PF30863 0.83 72.0 7.45e-01 94.2% 96.5%
5049040 1.1.1.0 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease 0.83 64.0 6.73e-01 80.2% 88.9%
3173885 2484.1.1.307 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Peptidase_A2B 0.83 67.0 7.13e-01 90.9% 96.2%
3168921 304.48.1.105 ↗ a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Peptidase_A2B 0.83 66.0 7.18e-01 90.1% 100.0%
3931384 1.1.1.0 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease 0.83 70.0 7.35e-01 99.2% 97.3%
3923745 1.1.1.18 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease › Asp_protease_2 0.82 78.0 7.73e-01 100.0% 96.8%
3934729 1.1.1.3 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease › RVP 0.82 74.0 7.34e-01 100.0% 92.0%
4969397 1.1.1.17 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease › RVP_2 0.82 72.0 7.43e-01 92.6% 97.4%
3929659 1.1.1.0 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease 0.82 77.0 7.41e-01 100.0% 94.1%
3735567 1.1.1.6 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease › Asp_protease 0.82 76.0 6.00e-01 100.0% 52.4%
3513100 1.1.1.8 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease › gag-asp_proteas 0.82 73.0 7.37e-01 96.7% 95.0%
4112343 1.1.1.3 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease › RVP 0.82 76.0 7.52e-01 98.3% 100.0%
4984762 1.1.1.17 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease › RVP_2 0.82 74.0 7.44e-01 95.0% 95.8%
3658254 1.1.1.0 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease 0.81 65.0 7.06e-01 86.8% 100.0%
4933012 1.1.1.8 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease › gag-asp_proteas 0.81 73.0 7.41e-01 95.9% 99.2%
3274948 1.1.1.0 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease 0.81 68.0 6.16e-01 95.0% 68.4%
3934130 1.1.1.0 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease 0.81 76.0 7.41e-01 100.0% 95.4%
3797665 1.1.1.0 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease 0.81 76.0 7.06e-01 100.0% 82.8%
3868675 1.1.1.6 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease › Asp_protease 0.81 76.0 6.64e-01 100.0% 70.6%
5032562 1.1.1.18 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease › Asp_protease_2 0.80 72.0 7.28e-01 95.0% 95.8%
3577579 1.1.1.14 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease › DUF1758 0.80 74.0 6.76e-01 98.3% 98.1%
3922986 1.1.1.8 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease › gag-asp_proteas 0.80 63.0 6.89e-01 81.8% 100.0%
3366156 1.1.1.0 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease 0.80 74.0 7.43e-01 97.5% 100.0%
3447999 1.1.1.17 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease › RVP_2 0.80 74.0 7.48e-01 98.3% 100.0%
3934416 1.1.1.17 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease › RVP_2 0.80 66.0 6.69e-01 100.0% 87.5%
3933581 1.1.1.3 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease › RVP 0.80 69.0 7.26e-01 93.4% 100.0%
3514088 1.1.1.14 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease › DUF1758 0.79 74.0 7.18e-01 100.0% 95.5%
3506070 1.1.1.0 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease 0.79 74.0 6.69e-01 100.0% 98.1%
4933942 1.1.1.8 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease › gag-asp_proteas 0.79 68.0 6.96e-01 94.2% 94.8%
3935794 1.1.1.6 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease › Asp_protease 0.79 73.0 6.88e-01 100.0% 82.8%
3797424 1.1.1.0 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease 0.79 74.0 6.57e-01 100.0% 92.1%
3579423 1.1.1.14 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease › DUF1758 0.79 73.0 6.76e-01 99.2% 98.0%
3924552 1.1.1.8 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease › gag-asp_proteas 0.79 69.0 7.00e-01 94.2% 93.3%
5031732 1.1.1.8 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease › gag-asp_proteas 0.79 68.0 6.98e-01 94.2% 95.7%
3773238 1.1.1.6 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease › Asp_protease 0.79 74.0 7.27e-01 100.0% 93.8%
4955517 1.1.1.0 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease 0.79 67.0 6.97e-01 91.7% 98.2%
3668951 1.1.1.17 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease › RVP_2 0.79 57.0 6.48e-01 77.7% 100.0%
4992338 1.1.1.18 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease › Asp_protease_2 0.79 64.0 6.83e-01 91.7% 99.0%
3793978 1.1.1.14 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease › DUF1758 0.79 73.0 6.53e-01 100.0% 96.4%
4968533 1.1.1.18 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease › Asp_protease_2 0.78 65.0 6.70e-01 86.8% 95.7%
3427964 1.1.1.17 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease › RVP_2 0.78 73.0 7.06e-01 100.0% 91.9%
3821648 1.1.1.17 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease › RVP_2 0.78 72.0 7.12e-01 98.3% 98.4%
3506977 1.1.1.0 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease 0.78 73.0 6.85e-01 100.0% 95.8%
3541617 1.1.1.6 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease › Asp_protease 0.78 71.0 7.17e-01 100.0% 96.7%
5030771 1.1.1.18 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease › Asp_protease_2 0.78 68.0 6.95e-01 95.0% 97.4%
4993656 1.1.1.3 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease › RVP 0.78 68.0 6.82e-01 92.6% 95.8%
3724349 1.1.1.18 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease › Asp_protease_2 0.77 73.0 6.94e-01 100.0% 97.1%
5031909 1.1.1.18 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease › Asp_protease_2 0.77 67.0 6.87e-01 94.2% 94.9%
5028105 1.1.1.1 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease › Asp 0.77 68.0 6.54e-01 93.4% 88.9%
3933744 1.1.1.0 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease 0.77 62.0 6.51e-01 85.1% 92.7%
3507687 1.1.1.14 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease › DUF1758 0.77 72.0 7.03e-01 100.0% 99.2%
3935726 1.1.1.18 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease › Asp_protease_2 0.77 66.0 6.80e-01 91.7% 95.6%
3824511 1.1.1.19 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease › Pol_BBD 0.77 64.0 6.44e-01 87.6% 94.2%
3937611 1.1.1.17 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease › RVP_2 0.77 64.0 6.69e-01 100.0% 96.4%
4969351 1.1.1.18 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease › Asp_protease_2 0.76 67.0 6.92e-01 100.0% 97.4%
3582847 1.1.2.30 ↗ beta barrels › cradle loop barrel › RIFT-related › double psi › DUF1758 0.76 66.0 6.55e-01 90.9% 96.0%
3928252 1.1.1.0 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease 0.76 63.0 6.64e-01 98.3% 96.3%
3517572 1.1.1.0 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease 0.76 67.0 6.88e-01 99.2% 98.3%
4969842 1.1.1.18 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease › Asp_protease_2 0.76 66.0 6.77e-01 94.2% 97.4%
3927612 1.1.1.17 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease › RVP_2 0.76 66.0 6.77e-01 92.6% 96.5%
3912599 1.1.1.8 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease › gag-asp_proteas 0.76 70.0 7.09e-01 100.0% 98.3%
3833862 1.1.1.0 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease 0.76 67.0 6.88e-01 94.2% 97.4%
3175039 1.1.1.19 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease › Pol_BBD 0.76 64.0 6.37e-01 100.0% 86.4%
4969904 1.1.1.18 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease › Asp_protease_2 0.76 67.0 6.45e-01 94.2% 84.4%
3516105 1.1.1.0 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease 0.76 71.0 6.80e-01 100.0% 97.0%
3931849 1.1.1.18 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease › Asp_protease_2 0.76 67.0 6.63e-01 93.4% 91.2%
5034399 1.1.1.18 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease › Asp_protease_2 0.76 67.0 6.46e-01 94.2% 88.7%
4928555 1.1.1.0 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease 0.75 66.0 6.55e-01 92.6% 92.7%
3972732 1.1.1.8 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease › gag-asp_proteas 0.75 63.0 6.23e-01 95.0% 84.5%
5031038 1.1.1.18 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease › Asp_protease_2 0.75 66.0 6.52e-01 93.4% 98.4%
3931343 1.1.1.18 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease › Asp_protease_2 0.75 63.0 6.53e-01 100.0% 93.9%
5073196 1.1.1.8 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease › gag-asp_proteas 0.75 65.0 6.50e-01 93.4% 91.1%
4993389 1.1.1.0 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease 0.75 65.0 6.55e-01 91.7% 93.3%
4968321 1.1.1.8 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease › gag-asp_proteas 0.75 62.0 6.62e-01 92.6% 100.0%
5031219 1.1.1.18 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease › Asp_protease_2 0.73 63.0 6.32e-01 91.7% 100.0%
4656484 1.1.1.5 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease › Zn_protease 0.72 67.0 6.18e-01 98.3% 89.3%
4001904 1.1.1.14 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease › DUF1758 0.72 54.0 6.05e-01 100.0% 100.0%
3969410 1.1.1.0 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease 0.72 60.0 6.14e-01 88.4% 100.0%
4999539 1.1.1.0 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease 0.71 62.0 6.23e-01 94.2% 99.2%
3846274 1.1.1.0 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease 0.71 63.0 6.52e-01 100.0% 98.3%
4993449 1.1.1.0 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease 0.69 57.0 6.06e-01 86.0% 100.0%
3992019 1.1.1.14 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease › DUF1758 0.67 61.0 6.01e-01 99.2% 96.2%
D2 high residues 600-673
PDB
Domain cluster: rep: polyprotein,_partial__YP_010085997__Schefflera_ringspot_virus__2169729__D61-133
CATH (31)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4ol8B03 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.84 71.0 6.60e-01 95.9% 74.4%
1st6A01 1.20.120.810 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Vinculin, Vh2 four-helix bundle 0.80 73.0 4.93e-01 100.0% 48.2%
3kavA00 1.20.1270.360 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.77 59.0 5.26e-01 81.1% 70.6%
3kyiA00 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.77 69.0 5.74e-01 100.0% 65.6%
2g3kA00 1.20.120.1130 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Vps28 C-terminal domain 0.75 67.0 6.21e-01 100.0% 95.7%
2p5tA00 1.10.8.130 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.72 54.0 5.03e-01 81.1% 81.5%
3geeA02 1.20.120.430 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › tRNA modification GTPase MnmE domain 2 0.70 62.0 4.80e-01 100.0% 67.9%
1jqkA03 1.20.1270.30 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.69 52.0 3.98e-01 81.1% 85.7%
2hsbA00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.69 58.0 5.03e-01 100.0% 86.5%
3efzB00 1.20.190.20 Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › 14-3-3 domain 0.65 46.0 3.30e-01 74.3% 30.2%
2i2oA00 1.25.40.180 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.65 45.0 3.30e-01 73.0% 56.9%
1sxjB03 1.20.272.10 Mainly Alpha › Up-down Bundle › Zinc Finger, Delta Prime; domain 3 › 0.64 53.0 5.01e-01 93.2% 96.7%
1f68A00 1.20.920.10 Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like 0.64 45.0 4.04e-01 73.0% 67.0%
7ep1B01 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.63 43.0 3.03e-01 70.3% 43.8%
1h6gA02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.63 52.0 4.58e-01 100.0% 90.3%
1qsdA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.63 43.0 3.90e-01 71.6% 100.0%
4jvsA01 1.20.120.1700 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.62 53.0 4.58e-01 100.0% 88.1%
1ze0A01 1.20.120.700 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › nitrate reductase, subunit delta (NarJ) 0.61 53.0 5.13e-01 100.0% 89.3%
1ic8A01 1.10.260.40 Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains 0.60 48.0 4.52e-01 90.5% 77.7%
3h0dB02 1.10.1200.150 Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › Transcriptional repressor of class III stress genes, C-terminal domain 0.60 52.0 5.07e-01 100.0% 93.8%
1j1jA02 1.20.58.200 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 0.59 42.0 4.05e-01 74.3% 91.8%
1sxjE03 1.20.272.10 Mainly Alpha › Up-down Bundle › Zinc Finger, Delta Prime; domain 3 › 0.57 48.0 4.49e-01 98.6% 94.8%
1wrdA00 1.20.58.160 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.56 38.0 3.58e-01 71.6% 83.7%
1yz5B00 1.20.190.20 Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › 14-3-3 domain 0.56 44.0 3.14e-01 86.5% 71.6%
2aboA00 1.10.437.10 Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like 0.54 47.0 3.98e-01 100.0% 92.4%
3f4mA00 1.20.1440.160 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Tumor necrosis factor alpha-induced protein 8-like 0.54 45.0 3.68e-01 98.6% 62.3%
3e0zA00 1.20.58.1400 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Domain of unknown function DUF3837 0.53 41.0 3.76e-01 91.9% 60.7%
3qpbF00 3.40.50.1580 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nucleoside phosphorylase domain 0.53 42.0 2.93e-01 86.5% 94.8%
2ph7A01 1.10.3400.10 Mainly Alpha › Orthogonal Bundle › af_2093 domain like fold › af_2093 domain like 0.53 33.0 2.87e-01 100.0% 37.9%
3tejA00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.51 40.0 2.69e-01 89.2% 52.8%
2o35A00 1.10.3340.10 Mainly Alpha › Orthogonal Bundle › SMc04008-like fold › SMc04008-like 0.50 37.0 3.72e-01 91.9% 77.2%
ECOD (52)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3925588 4967.1.1.0 ↗ alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.92 84.0 8.43e-01 100.0% 96.0%
3737899 4967.1.1.0 ↗ alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.91 83.0 8.08e-01 100.0% 90.0%
3937630 4967.1.1.0 ↗ alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.90 79.0 7.91e-01 100.0% 92.0%
3927913 4967.1.1.0 ↗ alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.89 81.0 8.06e-01 100.0% 96.0%
3926140 4967.1.1.0 ↗ alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.89 79.0 7.91e-01 100.0% 94.7%
3529289 4967.1.1.0 ↗ alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.89 80.0 8.02e-01 100.0% 96.0%
3926671 4967.1.1.0 ↗ alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.89 81.0 8.06e-01 100.0% 96.0%
4334565 4967.1.1.0 ↗ alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.88 79.0 7.94e-01 100.0% 96.0%
3924758 4967.1.1.0 ↗ alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.88 79.0 7.69e-01 100.0% 90.0%
3927489 4967.1.1.0 ↗ alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.88 79.0 7.92e-01 100.0% 96.0%
3924491 4967.1.1.0 ↗ alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.87 78.0 7.81e-01 100.0% 96.0%
3929753 4967.1.1.0 ↗ alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.87 80.0 7.96e-01 100.0% 97.3%
3845825 4967.1.1.0 ↗ alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.86 78.0 7.62e-01 100.0% 91.3%
3903902 4967.1.1.0 ↗ alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.85 78.0 7.59e-01 100.0% 91.3%
3254770 4967.1.1.0 ↗ alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.84 75.0 6.63e-01 100.0% 68.6%
4618809 4967.1.1.0 ↗ alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.84 77.0 7.18e-01 100.0% 92.2%
3933632 4967.1.1.0 ↗ alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.82 69.0 7.07e-01 98.6% 95.7%
3930367 4967.1.1.0 ↗ alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.82 74.0 7.38e-01 100.0% 97.3%
3937707 4967.1.1.0 ↗ alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.82 73.0 7.12e-01 100.0% 90.0%
3565220 633.23.1.22 ↗ alpha bundles › Bromodomain-like › Claudin › Claudin › MARVEL 0.78 59.0 4.70e-01 81.1% 59.3%
5074606 601.28.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › VPS28 C-terminal domain-like › VPS28 C-terminal domain-like 0.76 68.0 6.15e-01 100.0% 89.0%
3953156 601.3.1.5 ↗ alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Alpha-E 0.75 67.0 5.13e-01 100.0% 97.1%
4396656 601.55.1.4 ↗ alpha bundles › Four-helical up-and-down bundle › anti-complement domain of BBK32 › anti-complement domain of BBK32 › Alpha-E 0.75 67.0 5.11e-01 100.0% 97.1%
5053257 601.28.1.1 ↗ alpha bundles › Four-helical up-and-down bundle › VPS28 C-terminal domain-like › VPS28 C-terminal domain-like › VPS28 0.75 66.0 6.15e-01 100.0% 93.7%
54722 601.28.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › VPS28 C-terminal domain-like › VPS28 C-terminal domain-like 0.75 66.0 6.15e-01 100.0% 95.7%
4972207 601.28.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › VPS28 C-terminal domain-like › VPS28 C-terminal domain-like 0.74 64.0 6.09e-01 98.6% 93.3%
54382 601.1.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.74 65.0 5.52e-01 100.0% 95.2%
4999710 601.28.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › VPS28 C-terminal domain-like › VPS28 C-terminal domain-like 0.72 63.0 5.48e-01 100.0% 80.0%
5083350 601.7.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain 0.69 59.0 5.18e-01 100.0% 92.4%
4954528 601.7.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain 0.69 59.0 5.02e-01 100.0% 100.0%
4967769 601.7.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain 0.69 58.0 5.15e-01 98.6% 99.1%
5050149 601.7.1.2 ↗ alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HEPN 0.68 58.0 4.97e-01 100.0% 84.6%
4027781 138.1.1.2 ↗ alpha arrays › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › Rep_fac_C 0.68 54.0 4.99e-01 86.5% 94.7%
5054201 601.7.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain 0.68 59.0 5.26e-01 100.0% 98.2%
5029782 601.7.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain 0.68 51.0 4.85e-01 82.4% 92.2%
4944606 601.7.1.9 ↗ alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › Cas_Cas02710 0.68 57.0 4.46e-01 100.0% 79.4%
4939050 601.7.1.9 ↗ alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › Cas_Cas02710 0.68 58.0 4.44e-01 100.0% 81.1%
5028356 601.7.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain 0.67 58.0 4.96e-01 100.0% 88.0%
3546062 376.1.2.39 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › Cysteine-rich domain › RHG29_45_N 0.67 58.0 5.16e-01 100.0% 90.0%
3898895 601.1.1.68 ↗ alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › RHG29_45_N 0.66 58.0 5.05e-01 100.0% 84.3%
5081092 601.7.1.2 ↗ alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HEPN 0.66 56.0 4.86e-01 100.0% 88.6%
348731 109.4.1.1 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › 14-3-3 0.65 46.0 3.30e-01 74.3% 30.2%
3412831 7015.1.1.0 ↗ alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain 0.64 47.0 3.83e-01 79.7% 54.0%
5052086 601.7.1.2 ↗ alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HEPN 0.63 52.0 4.49e-01 100.0% 84.6%
3240466 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.60 43.0 3.96e-01 74.3% 92.6%
3498207 102.1.1.0 ↗ alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like 0.56 38.0 3.41e-01 70.3% 62.9%
4512923 181.1.1.1 ↗ alpha bundles › Domain of the SRP/SRP receptor G proteins-like › Domain of the SRP/SRP receptor G-proteins › Domain of the SRP/SRP receptor G-proteins › SRP54_N 0.56 45.0 4.39e-01 91.9% 90.6%
5041952 603.1.1.0 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.55 39.0 3.28e-01 75.7% 71.1%
3699646 610.1.1.1 ↗ alpha arrays › ERP29 C domain-like › ERP29 C domain-like › ERP29 C domain-like › ERp29 0.55 45.0 4.16e-01 91.9% 93.7%
3172910 603.1.1.99 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF27021 0.55 42.0 3.71e-01 81.1% 86.7%
3983395 2484.1.1.136 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › MutL 0.53 43.0 2.86e-01 90.5% 47.6%
3801576 4953.1.1.0 ↗ beta barrels › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like 0.51 37.0 3.49e-01 81.1% 72.0%
D3 high residues 677-818
PDB
Domain cluster: rep: polyprotein__YP_002916057__Sweet_potato_badnavirus_B__647294__D493-623
Pfam (3)
AccessionNameScoreE-valueQ covHMM cov
PF17917.8 best RT_RNaseH 53.3 3.70e-14 79.6% 89.5%
PF13456.13 RVT_3 21.9 2.00e-04 70.4% 72.4%
PF17919.8 RT_RNaseH_2 44.5 1.90e-11 59.2% 73.0%
D4 medium residues 357-456_492-515
PDB
Domain cluster: rep: pol_protein,_partial__YP_002308474__Simian_T-cell_lymphotropic_virus_6__481147__D16-81_108-143
D5 medium residues 457-491_516-594
PDB
Domain cluster: rep: IMGVR_UViG_3300021288_000040-3300021288-Ga0214511_10009611__D472-499_578-609_637-721
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00078.33 best RVT_1 58.7 1.00e-15 67.5% 40.5%