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rh92

Euk-Vir

Macacine_betaherpesvirus_3

rh92__YP_068185__Macacine_betaherpesvirus_3__47929

Identity

Accession:: YP_068185 ↗
Protein ID:: rh92
Kingdom:: euk

Quality

81.6 mean pLDDT

Taxonomy

Heunggongvirae› Peploviricota› Herviviricetes› Herpesvirales› Orthoherpesviridae› Cytomegalovirus› macacine_betaherpesvirus_3

TaxID: 47929

Cluster

View cluster (33 members)

3D Structure

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Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 1042-1102

PDB

Domain cluster: rep: major_DNA_binding_protein__NP_050222__Human_betaherpesvirus_6B__32604__D1005-1084

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF00747.23 best	Viral_DNA_bp	43.7	8.70e-12	100.0%	5.5%

D2 medium residues 1-257_715-744

PDB

Domain cluster: rep: ORF6__YP_001129352__Human_gammaherpesvirus_8__37296__D13-252_683-721

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF00747.23 best	Viral_DNA_bp	331.3	1.20e-98	90.6%	23.3%

D3 medium residues 258-315_368-409_505-520_628-644

PDB

Domain cluster: rep: BALF2__YP_001129510__Human_herpesvirus_4_type_2__12509__D237-306_328-386

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF00747.23 best	Viral_DNA_bp	50.7	7.00e-14	46.6%	5.1%

D4 medium residues 354-367_410-504

PDB

Domain cluster: rep: major_DNA_binding_protein__NP_050222__Human_betaherpesvirus_6B__32604__D414-501

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF00747.23 best	Viral_DNA_bp	115.7	1.60e-33	100.0%	8.5%

D5 medium residues 556-627

PDB

Domain cluster: representative

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF00747.23 best	Viral_DNA_bp	55.3	2.80e-15	100.0%	6.8%

CATH (21)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
2yqrA01	3.30.1370.10	Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1	0.69	57.0	5.06e-01	90.3%	87.4%
4nsmA00	6.10.250.2770	Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces ›	0.69	51.0	5.15e-01	88.9%	78.9%
2jqqA00	1.20.58.1240	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.68	50.0	3.88e-01	87.5%	36.4%
2q58B00	1.10.600.10	Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase	0.66	55.0	3.56e-01	91.7%	60.8%
1hs7A00	1.20.58.70	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.66	51.0	4.62e-01	84.7%	61.9%
4wz0A00	3.30.40.10	Alpha Beta › 2-Layer Sandwich › Herpes Virus-1 › Zinc/RING finger domain, C3HC4 (zinc finger)	0.62	44.0	3.89e-01	76.4%	81.7%
1w23A02	3.90.1150.10	Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1	0.61	43.0	3.83e-01	73.6%	55.3%
3nvoB02	1.20.58.340	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region	0.61	47.0	4.05e-01	87.5%	51.7%
5zyrA02	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.61	54.0	4.20e-01	98.6%	78.1%
1z23A00	1.20.120.830	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Serine-rich domain	0.60	53.0	4.13e-01	100.0%	86.5%
4h63H01	1.20.58.1710	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.60	49.0	5.00e-01	94.4%	91.7%
6i3mE01	1.20.120.420	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › translation initiation factor eif-2b, domain 1	0.59	49.0	4.03e-01	93.1%	51.8%
4egwA02	1.20.58.340	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region	0.59	52.0	4.39e-01	98.6%	72.3%
2fbhA00	1.10.10.10	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain	0.58	49.0	4.05e-01	98.6%	85.4%
6nd0A01	1.10.287.70	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.56	48.0	4.35e-01	97.2%	89.8%
4k5yA01	1.20.1070.10	Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins	0.55	47.0	3.22e-01	95.8%	27.0%
1e6bA02	1.20.1050.10	Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 ›	0.55	38.0	3.35e-01	75.0%	47.7%
5gotA00	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.54	41.0	3.28e-01	83.3%	96.7%
2lonA01	6.10.140.1320	Special › Helix non-globular › Helix Hairpins ›	0.53	40.0	4.22e-01	83.3%	95.4%
7zdgC02	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.52	36.0	2.59e-01	73.6%	23.3%
2kfdA00	1.10.10.440	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › FF domain	0.50	34.0	3.60e-01	76.4%	78.5%

ECOD (32)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3612403	7015.1.1.0 ↗	alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain	0.77	59.0	4.64e-01	88.9%	40.7%
3226769	386.1.1.0 ↗	few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers	0.68	51.0	5.15e-01	91.7%	81.4%
3243336	5001.1.1.33 ↗	alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srh	0.68	55.0	3.55e-01	87.5%	50.0%
4970576	375.1.1.179 ↗	few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › TFIIE_alpha	0.65	44.0	3.24e-01	70.8%	78.9%
5047150	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.64	53.0	3.81e-01	88.9%	91.0%
5064040	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.64	53.0	3.78e-01	88.9%	33.7%
5064397	5086.1.1.231 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › Rad50_zn_hook	0.64	53.0	3.81e-01	88.9%	35.4%
5050088	11.1.4.0 ↗	beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Prealbumin-like	0.63	45.0	3.20e-01	83.3%	25.9%
3716683	7015.1.1.0 ↗	alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain	0.63	57.0	4.54e-01	97.2%	59.3%
5019253	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.63	48.0	3.03e-01	81.9%	30.7%
3924372	2004.5.1.8 ↗	a/b three-layered sandwiches › P-loop domains-like › Differentially expressed in normal cells and neoplasia (DENN) domain › Differentially expressed in normal cells and neoplasia (DENN) domain › C9orf72-like	0.62	50.0	3.46e-01	86.1%	43.5%
3788027	5076.1.1.1 ↗	alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier › Mito_carr	0.62	50.0	3.36e-01	93.1%	23.9%
4789520	3719.1.1.0 ↗	alpha bundles › Imelysin peptidase-like › Imelysin peptidase-like › Imelysin peptidase-like	0.61	46.0	4.81e-01	87.5%	93.7%
2875713	376.1.1.18 ↗	few secondary structure elements › RING/U-box-like › RING/U-box-like › RING/U-box › zf-ANAPC11	0.61	38.0	3.24e-01	70.8%	39.5%
4874205	1075.4.1.1 ↗	alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane	0.60	54.0	3.75e-01	100.0%	97.9%
4478999	101.1.2.31 ↗	alpha arrays › HTH › HTH › winged helix domain › TFIIE_alpha	0.59	49.0	3.66e-01	88.9%	50.9%
3309008	375.1.1.246 ↗	few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › Rad50_zn_hook	0.59	48.0	4.24e-01	88.9%	62.9%
3266842	277.1.1.1 ↗	a+b two layers › PX domain › PX domain › PX domain › PX	0.59	45.0	3.76e-01	97.2%	47.2%
4505154	5001.1.1.3 ↗	alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_2	0.58	50.0	3.39e-01	98.6%	59.7%
5082704	375.1.1.179 ↗	few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › TFIIE_alpha	0.58	52.0	3.81e-01	100.0%	49.7%
4646072	101.1.2.31 ↗	alpha arrays › HTH › HTH › winged helix domain › TFIIE_alpha	0.57	47.0	3.54e-01	88.9%	88.2%
5037841	3826.1.1.0 ↗	alpha bundles › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR)	0.56	46.0	3.97e-01	97.2%	57.4%
3419529	170.2.1.0 ↗	alpha bundles › Retrovirus capsid protein › Retrovirus capsid protein N-terminal domain › Retrovirus capsid protein N-terminal domain	0.55	51.0	4.72e-01	100.0%	90.0%
3534741	192.8.1.276 ↗	alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › Rad50_zn_hook	0.55	47.0	2.72e-01	93.1%	43.0%
3494678	220.1.1.60 ↗	beta barrels › PH domain-like › PH domain-like › PH domain-like › ECT2_PH	0.55	50.0	3.42e-01	98.6%	52.8%
3229806	6157.1.1.1 ↗	alpha bundles › GKAP homology domain 1 › GKAP homology domain 1 › GKAP homology domain 1 › GKAP	0.54	43.0	3.83e-01	93.1%	59.1%
3583791	196.1.1.1 ↗	alpha bundles › Regulator of G-protein signaling, RGS › Regulator of G-protein signaling, RGS › Regulator of G-protein signaling, RGS › RGS	0.54	44.0	3.64e-01	91.7%	77.0%
4943395	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.53	43.0	3.29e-01	88.9%	43.5%
4344487	375.1.1.179 ↗	few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › TFIIE_alpha	0.53	42.0	3.23e-01	87.5%	87.9%
3469793	375.10.1.1 ↗	few secondary structure elements › Rubredoxin-like › Zinc finger domain of DNA polymerase-alpha › Zinc finger domain of DNA polymerase-alpha › zf-DNA_Pol	0.53	42.0	3.64e-01	97.2%	54.2%
4076504	7527.1.1.2 ↗	a/b three-layered sandwiches › SurE-like/CoA-transferase family III (CaiB/BaiF) › SurE-like/CoA-transferase family III (CaiB/BaiF) › SurE-like/CoA-transferase family III (CaiB/BaiF) › CoA_transf_3	0.52	37.0	2.39e-01	98.6%	14.3%
4164698	306.7.1.1 ↗	a+b two layers › Glucose permease domain IIB-like › Trigger factor ribosome-binding domain › Trigger factor ribosome-binding domain › Trigger_N	0.51	39.0	3.40e-01	81.9%	54.5%

D6 medium residues 767-826

PDB

Domain cluster: representative

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF00747.23 best	Viral_DNA_bp	80.5	6.50e-23	100.0%	5.1%

CATH (2)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
1vq8W02	1.10.15.30	Mainly Alpha › Orthogonal Bundle › 3-methyladenine DNA Glycosylase II; Chain A, domain 3 › Ribosomal protein L30/L7, central domain	0.55	40.0	4.18e-01	78.3%	100.0%
5cb1A02	1.10.150.20	Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 5' to 3' exonuclease, C-terminal subdomain	0.51	34.0	3.44e-01	73.3%	85.7%