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ribonucleoside-diphosphate_reductase_large_chain

Euk-Vir

Tunisvirus_fontaine2

ribonucleoside-diphosphate_reductase_large_chain__YP_009506879__Tunisvirus_fontaine2__1421067

Identity

Accession:
YP_009506879 ↗
Protein ID:
ribonucleoside-diphosphate_reductase_large_chain
Kingdom:
euk

Quality

77.9 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 1-75_89-134
PDB
Domain cluster: representative
CATH (2)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2pqrA01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.54 37.0 4.15e-01 77.7% 90.3%
2g3vA00 1.20.120.1140 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CAG pathogenicity island protein 13, CagS 0.51 39.0 3.61e-01 95.0% 61.5%
ECOD (4)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3519243 1074.1.1.0 alpha arrays › Alpha helical domain of ribonucleotide reductases › Alpha helical domain of ribonucleotide reductases › Alpha helical domain of ribonucleotide reductases 0.92 85.0 6.97e-01 96.7% 74.0%
3607359 103.2.1.1 alpha arrays › RuvA-C › ATP cone › ATP cone › Ribonuc_red_lgN 0.91 87.0 7.09e-01 100.0% 73.2%
3721863 109.4.1.217 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fis1_TPR_N,Fis1_TPR_C 0.54 37.0 3.63e-01 78.5% 65.4%
3845048 170.1.1.25 alpha bundles › Retrovirus capsid protein › Retrovirus capsid protein-C › Retrovirus capsid protein-C › PNMA 0.51 39.0 4.12e-01 82.6% 93.3%
D2 medium residues 76-88_135-177
PDB
Domain cluster: representative
CATH (4)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2fnaA02 1.10.8.60 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.63 49.0 4.55e-01 89.3% 76.3%
3lcvB01 1.10.8.10 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ubiquitin-associated (UBA) domain 0.57 47.0 4.75e-01 89.3% 93.0%
3b89A01 1.10.8.10 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ubiquitin-associated (UBA) domain 0.55 44.0 4.54e-01 89.3% 90.7%
3qwlA02 1.10.8.680 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ypt/Rab-GAP domain of gyp1p, domain 2 0.53 40.0 3.71e-01 85.7% 81.8%
ECOD (7)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3519243 1074.1.1.0 alpha arrays › Alpha helical domain of ribonucleotide reductases › Alpha helical domain of ribonucleotide reductases › Alpha helical domain of ribonucleotide reductases 0.98 93.0 6.06e-01 100.0% 54.0%
3607359 103.2.1.1 alpha arrays › RuvA-C › ATP cone › ATP cone › Ribonuc_red_lgN 0.97 92.0 5.95e-01 100.0% 55.1%
3594035 1074.1.1.0 alpha arrays › Alpha helical domain of ribonucleotide reductases › Alpha helical domain of ribonucleotide reductases › Alpha helical domain of ribonucleotide reductases 0.97 91.0 6.68e-01 100.0% 86.9%
3277072 1074.1.1.1 alpha arrays › Alpha helical domain of ribonucleotide reductases › Alpha helical domain of ribonucleotide reductases › Alpha helical domain of ribonucleotide reductases › Ribonuc_red_lgN 0.97 91.0 6.34e-01 100.0% 69.7%
4102625 132.3.1.1 alpha bundles › ACP-like › Hypothetical protein YjbJ › Hypothetical protein YjbJ › CsbD 0.55 37.0 3.62e-01 75.0% 65.0%
4635810 148.1.3.173 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › AAA_lid_RFC1 0.54 46.0 4.38e-01 92.9% 96.9%
3939049 148.1.3.0 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.50 41.0 4.02e-01 92.9% 91.7%
D3 medium residues 190-303_373-393
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02867.21 best Ribonuc_red_lgC 95.1 5.70e-27 97.8% 22.3%
D4 medium residues 304-372
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02867.21 best Ribonuc_red_lgC 70.5 1.60e-19 100.0% 13.2%
D5 medium residues 503-575
PDB
D6 medium residues 630-735
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02867.21 best Ribonuc_red_lgC 102.2 4.10e-29 100.0% 19.9%
D7 medium residues 736-828
PDB
Domain cluster: representative
CATH (8)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4fqgA02 1.10.10.440 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › FF domain 0.55 30.0 3.56e-01 90.3% 80.3%
7zdtD01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.53 45.0 3.22e-01 100.0% 86.5%
2i2xB01 1.10.1240.10 Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain 0.52 36.0 3.54e-01 98.9% 66.0%
5nl6A02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.52 42.0 4.07e-01 100.0% 78.7%
1t72A02 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.52 41.0 4.05e-01 100.0% 82.7%
3vouB00 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.51 39.0 3.52e-01 83.9% 58.8%
4jgiA01 1.10.1240.10 Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain 0.50 34.0 3.64e-01 100.0% 82.5%
2ms7A00 1.10.533.10 Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas 0.50 35.0 3.45e-01 73.1% 99.0%
ECOD (5)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4927557 601.7.1.0 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain 0.58 47.0 4.44e-01 97.8% 73.0%
3740780 604.12.1.2 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › Vta1 0.53 37.0 4.01e-01 100.0% 89.3%
4941477 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.53 36.0 3.60e-01 83.9% 66.0%
3675610 101.1.2.386 alpha arrays › HTH › HTH › winged helix domain › WH_DRP 0.52 32.0 3.09e-01 98.9% 52.4%
3491110 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.50 43.0 4.09e-01 100.0% 81.8%