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ribonucleoside-diphosphate_reductase_small_chain
Euk-VirPithovirus_sibericum
ribonucleoside-diphosphate_reductase_small_chain__YP_009001342__Pithovirus_sibericum__1450746
Identity
- Accession:
- YP_009001342 ↗
- Protein ID:
- ribonucleoside-diphosphate_reductase_small_chain
- Kingdom:
- euk
Quality
85.7
mean pLDDT
Cluster
View cluster (111 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 39-162
Domain cluster:
rep: JM118__YP_238421__Macaca_fuscata_rhadinovirus__272551__D34-136
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00268.28 best | Ribonuc_red_sm | 102.1 | 5.00e-29 | 100.0% | 43.1% |
CATH (48)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1h0oA00 | 1.10.620.20 | Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A | 0.97 | 94.0 | 6.81e-01 | 100.0% | 43.1% |
| 2aniA00 | 1.10.620.20 | Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A | 0.92 | 87.0 | 6.22e-01 | 100.0% | 38.8% |
| 1biqA00 | 1.10.620.20 | Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A | 0.91 | 84.0 | 5.93e-01 | 100.0% | 35.6% |
| 4bmoA00 | 1.10.620.20 | Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A | 0.89 | 84.0 | 6.19e-01 | 100.0% | 42.4% |
| 3ee4A00 | 1.10.620.20 | Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A | 0.86 | 81.0 | 5.98e-01 | 100.0% | 42.6% |
| 6eboA00 | 1.10.620.20 | Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A | 0.86 | 80.0 | 5.82e-01 | 100.0% | 39.5% |
| 5olkB01 | 1.10.620.20 | Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A | 0.84 | 76.0 | 5.73e-01 | 100.0% | 42.7% |
| 2rccA01 | 1.10.620.20 | Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A | 0.84 | 78.0 | 5.98e-01 | 100.0% | 47.1% |
| 2incA00 | 1.10.620.20 | Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A | 0.82 | 76.0 | 4.97e-01 | 100.0% | 34.0% |
| 3bt5A00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.79 | 52.0 | 4.85e-01 | 79.0% | 55.0% |
| 3u52D00 | 1.10.620.20 | Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A | 0.79 | 73.0 | 5.26e-01 | 100.0% | 40.5% |
| 1mhyD00 | 1.10.620.20 | Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A | 0.78 | 73.0 | 4.73e-01 | 100.0% | 26.7% |
| 4mudC00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.78 | 58.0 | 4.68e-01 | 81.5% | 43.2% |
| 1jgcA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.78 | 49.0 | 4.46e-01 | 79.8% | 49.4% |
| 4a5dB00 | 1.10.620.20 | Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A | 0.77 | 68.0 | 5.33e-01 | 96.0% | 48.7% |
| 2vxxA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.76 | 54.0 | 4.83e-01 | 81.5% | 52.9% |
| 4rngC00 | 1.20.1280.290 | Mainly Alpha › Up-down Bundle › Monooxygenase › | 0.74 | 49.0 | 5.89e-01 | 79.8% | 100.0% |
| 5hyhA00 | 1.10.620.20 | Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A | 0.73 | 68.0 | 5.08e-01 | 100.0% | 53.7% |
| 8ex5A02 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.70 | 50.0 | 4.10e-01 | 74.2% | 71.6% |
| 5ux2B01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.68 | 55.0 | 4.45e-01 | 83.1% | 72.0% |
| 2oc5A01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.68 | 54.0 | 4.41e-01 | 83.1% | 63.7% |
| 2ntxA01 | 1.20.58.2010 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › PRONE domain, subdomain 1 | 0.68 | 52.0 | 4.33e-01 | 80.6% | 89.5% |
| 4egwA02 | 1.20.58.340 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region | 0.68 | 52.0 | 5.38e-01 | 80.6% | 94.1% |
| 1jkvA01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.67 | 56.0 | 4.76e-01 | 88.7% | 63.5% |
| 4qndA00 | 1.20.1280.290 | Mainly Alpha › Up-down Bundle › Monooxygenase › | 0.66 | 45.0 | 4.97e-01 | 87.9% | 87.6% |
| 1ek9A00 | 1.20.1600.10 | Mainly Alpha › Up-down Bundle › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) | 0.66 | 51.0 | 3.44e-01 | 80.6% | 60.7% |
| 2lm9A00 | 1.20.58.970 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.65 | 48.0 | 5.41e-01 | 76.6% | 100.0% |
| 5cy5B00 | 1.20.1200.10 | Mainly Alpha › Up-down Bundle › Hypothetical Protein Ta1238; Chain: A; › Cobalamin adenosyltransferase-like | 0.65 | 51.0 | 4.74e-01 | 83.9% | 67.8% |
| 2rdcA00 | 1.10.287.800 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › protein ne1242 | 0.64 | 44.0 | 4.32e-01 | 70.2% | 86.5% |
| 6h2dS01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.63 | 48.0 | 3.89e-01 | 79.0% | 84.8% |
| 1f6fA00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.62 | 51.0 | 4.37e-01 | 84.7% | 67.2% |
| 3zevB00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.62 | 48.0 | 3.64e-01 | 81.5% | 69.7% |
| 8sbeA01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.61 | 44.0 | 3.79e-01 | 74.2% | 74.5% |
| 5ux1D00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.61 | 56.0 | 4.74e-01 | 98.4% | 88.3% |
| 1oahA02 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.61 | 45.0 | 4.32e-01 | 76.6% | 81.7% |
| 2l7nA00 | 1.20.1420.10 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain | 0.60 | 47.0 | 4.30e-01 | 83.1% | 95.8% |
| 1za0A00 | 1.10.620.20 | Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A | 0.60 | 55.0 | 4.34e-01 | 97.6% | 78.5% |
| 2kbbA00 | 1.20.1420.10 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain | 0.58 | 48.0 | 4.28e-01 | 87.9% | 94.3% |
| 2o36A01 | 1.20.1050.40 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › Endopeptidase. Chain P; domain 1 | 0.57 | 45.0 | 4.55e-01 | 87.1% | 92.2% |
| 2z0qA01 | 1.20.900.10 | Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain | 0.56 | 42.0 | 3.69e-01 | 79.0% | 54.4% |
| 2l10A00 | 1.20.1420.10 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain | 0.56 | 46.0 | 4.34e-01 | 90.3% | 98.7% |
| 5lweA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.56 | 43.0 | 3.40e-01 | 82.3% | 65.1% |
| 2qr4A01 | 1.20.140.70 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Oligopeptidase f, N-terminal domain | 0.55 | 45.0 | 4.16e-01 | 86.3% | 76.3% |
| 3kp9A01 | 1.20.1440.130 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › VKOR domain | 0.55 | 49.0 | 4.53e-01 | 99.2% | 80.2% |
| 3dyjA02 | 1.20.1420.10 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain | 0.54 | 45.0 | 4.19e-01 | 87.1% | 95.4% |
| 1a22A00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.54 | 43.0 | 3.79e-01 | 84.7% | 81.7% |
| 3gi7A00 | 1.20.1270.180 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.52 | 40.0 | 4.34e-01 | 79.0% | 97.1% |
| 5x9vA01 | 1.10.560.10 | Mainly Alpha › Orthogonal Bundle › GROEL; domain 1 › GroEL-like equatorial domain | 0.52 | 41.0 | 3.29e-01 | 83.9% | 77.6% |
ECOD (87)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3470297 | 150.1.2.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase | 0.97 | 94.0 | 6.54e-01 | 100.0% | 37.0% |
| 4603349 | 150.1.2.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › Ribonuc_red_sm | 0.96 | 94.0 | 6.41e-01 | 100.0% | 35.2% |
| 3274715 | 150.1.2.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › Ribonuc_red_sm | 0.96 | 93.0 | 7.41e-01 | 100.0% | 57.7% |
| 3807411 | 150.1.1.174 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Ribonuc_red_sm | 0.95 | 90.0 | 8.52e-01 | 97.6% | 86.4% |
| 4481595 | 150.1.2.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › Ribonuc_red_sm | 0.92 | 87.0 | 6.13e-01 | 100.0% | 37.0% |
| 1726039 | 150.1.2.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › Ribonuc_red_sm | 0.92 | 86.0 | 6.01e-01 | 100.0% | 35.7% |
| 3968133 | 150.1.2.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › Ribonuc_red_sm | 0.92 | 88.0 | 6.11e-01 | 100.0% | 35.4% |
| 436631 | 150.1.2.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › Ribonuc_red_sm | 0.91 | 85.0 | 5.89e-01 | 100.0% | 34.4% |
| 56518 | 150.1.2.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase | 0.91 | 84.0 | 5.92e-01 | 100.0% | 35.7% |
| 4340194 | 150.1.2.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › Ribonuc_red_sm | 0.90 | 86.0 | 6.20e-01 | 100.0% | 40.7% |
| 56563 | 150.1.2.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase | 0.90 | 84.0 | 6.25e-01 | 100.0% | 43.3% |
| 4026999 | 150.1.2.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › Ribonuc_red_sm | 0.89 | 85.0 | 6.12e-01 | 100.0% | 41.0% |
| 151585 | 150.1.2.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › Ribonuc_red_sm | 0.88 | 83.0 | 6.28e-01 | 100.0% | 46.3% |
| 4267558 | 150.1.2.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › Ribonuc_red_sm | 0.87 | 82.0 | 5.86e-01 | 100.0% | 38.6% |
| 5009513 | 150.1.2.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › Ribonuc_red_sm | 0.87 | 83.0 | 5.89e-01 | 100.0% | 38.7% |
| 5009507 | 150.1.2.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › Ribonuc_red_sm | 0.86 | 82.0 | 5.85e-01 | 100.0% | 38.8% |
| 2391405 | 150.1.2.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › Ribonuc_red_sm | 0.86 | 81.0 | 5.83e-01 | 100.0% | 39.2% |
| 2846952 | 150.1.2.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › Ribonuc_red_sm | 0.86 | 80.0 | 5.83e-01 | 100.0% | 39.3% |
| 5009559 | 150.1.2.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › Ribonuc_red_sm | 0.86 | 82.0 | 5.91e-01 | 100.0% | 40.7% |
| 2388926 | 150.1.2.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › Ribonuc_red_sm | 0.85 | 77.0 | 5.66e-01 | 100.0% | 39.7% |
| 1684591 | 150.1.2.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › Ribonuc_red_sm | 0.84 | 79.0 | 5.85e-01 | 100.0% | 42.9% |
| 3165999 | 3291.1.1.213 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › MscS_porin | 0.78 | 59.0 | 4.89e-01 | 79.0% | 73.3% |
| 3284093 | 150.1.1.132 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › AurF | 0.76 | 71.0 | 5.14e-01 | 100.0% | 44.7% |
| 3948661 | 3860.1.1.167 ↗ | alpha bundles › Myosin VI lever arm › Myosin VI lever arm › Myosin VI lever arm › MscS_porin | 0.74 | 69.0 | 4.75e-01 | 100.0% | 60.3% |
| 3984201 | 192.2.1.73 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › MscS_porin | 0.74 | 69.0 | 4.58e-01 | 100.0% | 52.2% |
| 3394434 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.74 | 55.0 | 4.39e-01 | 76.6% | 65.2% |
| 3287253 | 150.1.2.6 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › FA_desaturase_2 | 0.74 | 66.0 | 4.75e-01 | 95.2% | 72.3% |
| 3974233 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.73 | 52.0 | 4.52e-01 | 74.2% | 78.8% |
| 4997306 | 5059.1.1.1 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA | 0.72 | 52.0 | 3.90e-01 | 74.2% | 50.9% |
| 3901936 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.72 | 51.0 | 4.25e-01 | 73.4% | 68.4% |
| 3732054 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.72 | 53.0 | 4.57e-01 | 76.6% | 79.5% |
| 3720301 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.72 | 51.0 | 4.38e-01 | 74.2% | 75.4% |
| 3988033 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.72 | 51.0 | 4.39e-01 | 72.6% | 78.9% |
| 3179246 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.70 | 55.0 | 4.06e-01 | 82.3% | 52.6% |
| 4410536 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.70 | 50.0 | 4.31e-01 | 74.2% | 77.9% |
| 3786025 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.70 | 50.0 | 4.12e-01 | 73.4% | 71.6% |
| 3787103 | 1203.1.2.0 ↗ | alpha bundles › Shroom domain 2 › Shroom domain 2 › Human SD2 | 0.70 | 52.0 | 5.03e-01 | 77.4% | 81.4% |
| 3288375 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.69 | 48.0 | 4.10e-01 | 71.0% | 72.8% |
| 3444788 | 150.1.2.6 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › FA_desaturase_2 | 0.69 | 63.0 | 5.18e-01 | 100.0% | 68.0% |
| 5026259 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.69 | 49.0 | 4.16e-01 | 73.4% | 76.0% |
| 3671851 | 5086.1.1.47 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › Auxin_canalis | 0.68 | 47.0 | 4.57e-01 | 74.2% | 63.7% |
| 4408929 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.68 | 51.0 | 4.07e-01 | 79.0% | 64.9% |
| 4618341 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.68 | 50.0 | 4.19e-01 | 76.6% | 73.7% |
| 3953260 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.67 | 50.0 | 4.19e-01 | 78.2% | 72.9% |
| 3564754 | 604.1.1.96 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Bap31 | 0.67 | 50.0 | 4.94e-01 | 79.0% | 96.3% |
| 4946929 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.67 | 51.0 | 4.18e-01 | 80.6% | 70.2% |
| 3788506 | 6155.1.1.2 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › PQ-loop | 0.66 | 60.0 | 5.60e-01 | 98.4% | 100.0% |
| 4459896 | 622.4.1.1 ↗ | alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related › Blo-t-5 | 0.66 | 52.0 | 5.39e-01 | 80.6% | 100.0% |
| 4113314 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.66 | 47.0 | 3.89e-01 | 74.2% | 69.3% |
| 4259041 | 150.3.1.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › 4-helical cytokines › 4-helical cytokine › Hormone_1 | 0.66 | 53.0 | 4.46e-01 | 83.9% | 74.4% |
| 3284087 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.65 | 50.0 | 3.94e-01 | 81.5% | 59.2% |
| 3743762 | 6155.1.1.0 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter | 0.64 | 58.0 | 5.22e-01 | 99.2% | 97.6% |
| 3619687 | 604.1.1.127 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › EMC4 | 0.64 | 49.0 | 5.21e-01 | 83.1% | 90.9% |
| 3819179 | 632.7.1.62 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain › DUF641 | 0.63 | 45.0 | 4.33e-01 | 75.0% | 65.0% |
| 3774605 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.63 | 51.0 | 4.46e-01 | 84.7% | 91.7% |
| 3225376 | 601.1.3.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › A middle domain of Talin 1 | 0.62 | 47.0 | 4.44e-01 | 78.2% | 92.7% |
| 3541314 | 5069.1.1.4 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Ferric_reduct | 0.61 | 55.0 | 4.21e-01 | 99.2% | 93.8% |
| 3549568 | 5069.1.1.4 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Ferric_reduct | 0.61 | 54.0 | 4.60e-01 | 100.0% | 91.9% |
| 3637900 | 6155.1.1.2 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › PQ-loop | 0.60 | 53.0 | 4.91e-01 | 96.8% | 100.0% |
| 5056066 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.60 | 49.0 | 4.14e-01 | 87.9% | 75.2% |
| 2642997 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.60 | 47.0 | 4.08e-01 | 83.9% | 73.2% |
| 3642887 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.60 | 46.0 | 3.81e-01 | 81.5% | 65.5% |
| 3722421 | 604.8.1.0 ↗ | alpha bundles › Spectrin repeat-like › Smac/diablo › Smac/diablo | 0.59 | 44.0 | 4.22e-01 | 76.6% | 87.1% |
| 3225373 | 601.1.1.6 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › TLN1-like_RS | 0.59 | 48.0 | 4.40e-01 | 86.3% | 97.6% |
| 3861221 | 601.1.2.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) | 0.59 | 47.0 | 4.19e-01 | 84.7% | 94.4% |
| 3533017 | 150.3.1.6 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › 4-helical cytokines › 4-helical cytokine › IL10 | 0.59 | 50.0 | 4.63e-01 | 96.0% | 71.6% |
| 3924530 | 603.2.1.0 ↗ | alpha bundles › STAT-like › STAT › STAT | 0.59 | 48.0 | 3.50e-01 | 88.7% | 53.2% |
| 3977166 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.59 | 45.0 | 3.73e-01 | 81.5% | 70.2% |
| 3741125 | 601.1.2.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) | 0.58 | 43.0 | 3.64e-01 | 76.6% | 54.9% |
| 3712828 | 6155.1.1.2 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › PQ-loop | 0.58 | 50.0 | 5.00e-01 | 100.0% | 93.6% |
| 4950367 | 622.1.1.0 ↗ | alpha bundles › YvfG-like › HSC20 (HSCB), C-terminal oligomerisation domain › HSC20 (HSCB), C-terminal oligomerisation domain | 0.58 | 41.0 | 4.05e-01 | 72.6% | 69.2% |
| 3745002 | 601.1.1.98 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › PF27524 | 0.57 | 46.0 | 4.31e-01 | 87.9% | 94.8% |
| 4019453 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.56 | 46.0 | 3.65e-01 | 87.1% | 61.6% |
| 3861669 | 601.1.2.63 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › HIP1R | 0.56 | 46.0 | 4.35e-01 | 89.5% | 96.8% |
| 5032686 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.56 | 45.0 | 3.87e-01 | 85.5% | 72.3% |
| 3606999 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.56 | 44.0 | 3.55e-01 | 83.9% | 61.3% |
| 3631469 | 601.14.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin | 0.56 | 51.0 | 4.47e-01 | 99.2% | 89.4% |
| 3225375 | 601.1.3.6 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › A middle domain of Talin 1 › Talin_IBS2B | 0.55 | 45.0 | 4.13e-01 | 86.3% | 96.2% |
| 3923617 | 603.1.1.109 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › DUF267 | 0.55 | 51.0 | 3.58e-01 | 100.0% | 61.8% |
| 3638405 | 633.21.1.0 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 | 0.55 | 49.0 | 4.47e-01 | 96.8% | 89.7% |
| 3198311 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.55 | 46.0 | 3.85e-01 | 88.7% | 72.2% |
| 5024514 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.54 | 44.0 | 4.16e-01 | 85.5% | 92.4% |
| 3707035 | 5050.1.1.22 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1_like | 0.53 | 42.0 | 3.56e-01 | 83.1% | 65.9% |
| 3584767 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.53 | 43.0 | 3.47e-01 | 86.3% | 65.5% |
| 4352176 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.52 | 43.0 | 3.31e-01 | 86.3% | 55.2% |
| 5009845 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.52 | 43.0 | 3.63e-01 | 86.3% | 69.5% |
| 3694404 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.52 | 42.0 | 3.42e-01 | 86.3% | 59.1% |
D2
medium
residues 163-306
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00268.28 best | Ribonuc_red_sm | 106.2 | 2.80e-30 | 93.1% | 45.6% |
CATH (50)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4a5dB00 | 1.10.620.20 | Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A | 0.92 | 78.0 | 6.44e-01 | 86.8% | 54.3% |
| 1h0oA00 | 1.10.620.20 | Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A | 0.92 | 87.0 | 6.61e-01 | 99.3% | 48.6% |
| 5olkB01 | 1.10.620.20 | Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A | 0.91 | 88.0 | 6.82e-01 | 100.0% | 57.7% |
| 1biqA00 | 1.10.620.20 | Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A | 0.91 | 87.0 | 6.37e-01 | 100.0% | 54.7% |
| 2aniA00 | 1.10.620.20 | Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A | 0.91 | 87.0 | 6.46e-01 | 99.3% | 50.2% |
| 6eboA00 | 1.10.620.20 | Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A | 0.87 | 83.0 | 6.26e-01 | 100.0% | 47.9% |
| 4bmoA00 | 1.10.620.20 | Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A | 0.87 | 83.0 | 6.39e-01 | 100.0% | 53.1% |
| 4mudC00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.75 | 62.0 | 5.34e-01 | 90.3% | 57.3% |
| 3wmeA01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.68 | 56.0 | 4.28e-01 | 86.1% | 90.0% |
| 7wivA01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.68 | 55.0 | 4.29e-01 | 86.1% | 91.2% |
| 6bl6B01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.67 | 54.0 | 4.19e-01 | 86.1% | 91.1% |
| 3pmcA00 | 1.10.490.70 | Mainly Alpha › Orthogonal Bundle › Globin-like › Histidine kinase N-terminal domain | 0.67 | 49.0 | 5.15e-01 | 88.2% | 83.3% |
| 5hyhA00 | 1.10.620.20 | Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A | 0.67 | 57.0 | 4.49e-01 | 91.0% | 76.7% |
| 3l8rA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.66 | 44.0 | 5.15e-01 | 96.5% | 96.1% |
| 3h36A00 | 1.10.10.400 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Polyribonucleotide nucleotidyltransferase, RNA-binding domain | 0.65 | 35.0 | 4.58e-01 | 70.8% | 94.9% |
| 4o6kA00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.64 | 38.0 | 3.98e-01 | 75.7% | 62.5% |
| 4mrsA01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.63 | 50.0 | 3.87e-01 | 86.1% | 86.5% |
| 3r2qA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.61 | 44.0 | 4.92e-01 | 87.5% | 94.7% |
| 2y39A00 | 1.20.120.1490 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.61 | 38.0 | 4.32e-01 | 81.2% | 80.9% |
| 4q4hB01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.60 | 49.0 | 3.74e-01 | 86.8% | 87.4% |
| 1q0gA00 | 1.20.120.400 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nickel-containing superoxide dismutase | 0.59 | 42.0 | 4.68e-01 | 84.0% | 89.7% |
| 3n98A02 | 1.20.1430.10 | Mainly Alpha › Up-down Bundle › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase, middle domain | 0.59 | 39.0 | 4.10e-01 | 82.6% | 72.4% |
| 1yo7A00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.59 | 37.0 | 4.04e-01 | 95.8% | 75.8% |
| 3dbyL00 | 1.20.1260.120 | Mainly Alpha › Up-down Bundle › Ferritin › Protein of unknown function DUF2935 | 0.57 | 42.0 | 3.49e-01 | 76.4% | 93.5% |
| 1fewA00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.57 | 50.0 | 4.71e-01 | 96.5% | 77.5% |
| 1t98A02 | 1.20.58.590 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Chromosome partition protein MukF, middle domain | 0.57 | 44.0 | 4.29e-01 | 82.6% | 94.5% |
| 3qavA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.57 | 48.0 | 4.88e-01 | 97.2% | 94.3% |
| 3wvoC02 | 1.10.132.100 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › | 0.56 | 46.0 | 4.88e-01 | 86.1% | 97.7% |
| 2cmrA00 | 1.20.58.1860 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.56 | 50.0 | 4.52e-01 | 94.4% | 96.4% |
| 1ka2A00 | 1.10.1370.30 | Mainly Alpha › Orthogonal Bundle › Neurolysin; domain 3 › | 0.55 | 49.0 | 3.37e-01 | 96.5% | 81.9% |
| 1j30A00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.55 | 44.0 | 4.47e-01 | 89.6% | 85.1% |
| 1orjD00 | 1.20.120.340 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS | 0.55 | 37.0 | 4.01e-01 | 80.6% | 80.0% |
| 1y4cA03 | 1.20.120.660 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain | 0.54 | 41.0 | 4.59e-01 | 83.3% | 99.1% |
| 1fioA00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.54 | 49.0 | 4.46e-01 | 96.5% | 81.6% |
| 1xg2B00 | 1.20.140.40 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein | 0.54 | 35.0 | 3.53e-01 | 100.0% | 61.6% |
| 1qdbA02 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.54 | 41.0 | 4.18e-01 | 93.1% | 80.4% |
| 1sziA02 | 1.20.120.340 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS | 0.53 | 43.0 | 4.39e-01 | 84.7% | 87.6% |
| 5fhiA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.53 | 44.0 | 4.55e-01 | 95.8% | 93.5% |
| 6w08A01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.53 | 44.0 | 3.34e-01 | 88.9% | 97.4% |
| 1bf5A01 | 1.20.1050.20 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › STAT transcription factor, all-alpha domain | 0.53 | 47.0 | 4.44e-01 | 97.2% | 81.0% |
| 3ajmB02 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.53 | 41.0 | 4.25e-01 | 85.4% | 86.5% |
| 2yfaA02 | 1.20.1440.210 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.53 | 37.0 | 4.02e-01 | 75.0% | 88.8% |
| 7p3rA01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.52 | 38.0 | 2.95e-01 | 74.3% | 88.6% |
| 2o36A01 | 1.20.1050.40 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › Endopeptidase. Chain P; domain 1 | 0.52 | 41.0 | 4.30e-01 | 95.8% | 93.8% |
| 5ojcA00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.52 | 41.0 | 4.00e-01 | 87.5% | 77.3% |
| 6adqG01 | 1.20.120.80 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle | 0.51 | 41.0 | 3.84e-01 | 84.0% | 76.4% |
| 3qxlA00 | 1.10.840.10 | Mainly Alpha › Orthogonal Bundle › Son of Sevenless (SoS) protein; Chain S, domain 2 › Ras guanine-nucleotide exchange factors catalytic domain | 0.51 | 46.0 | 3.87e-01 | 98.6% | 70.2% |
| 3kflA03 | 1.10.730.10 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 | 0.51 | 38.0 | 3.59e-01 | 77.1% | 68.6% |
| 6a3kA00 | 1.20.120.10 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 | 0.50 | 41.0 | 4.35e-01 | 85.4% | 98.4% |
| 3zsuA00 | 1.20.120.290 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle | 0.50 | 38.0 | 4.14e-01 | 83.3% | 95.8% |
ECOD (39)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4488174 | 150.1.2.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › Ribonuc_red_sm | 0.92 | 88.0 | 6.50e-01 | 100.0% | 49.4% |
| 4481595 | 150.1.2.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › Ribonuc_red_sm | 0.92 | 88.0 | 6.48e-01 | 100.0% | 49.1% |
| 3470297 | 150.1.2.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase | 0.92 | 89.0 | 6.46e-01 | 100.0% | 43.3% |
| 162837 | 150.1.2.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › Ribonuc_red_sm | 0.92 | 87.0 | 6.63e-01 | 99.3% | 49.0% |
| 4026999 | 150.1.2.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › Ribonuc_red_sm | 0.91 | 86.0 | 6.46e-01 | 99.3% | 45.5% |
| 4603349 | 150.1.2.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › Ribonuc_red_sm | 0.91 | 88.0 | 6.33e-01 | 100.0% | 40.6% |
| 3968133 | 150.1.2.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › Ribonuc_red_sm | 0.91 | 88.0 | 6.35e-01 | 100.0% | 47.4% |
| 3386562 | 150.1.2.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › Ribonuc_red_sm | 0.91 | 88.0 | 6.47e-01 | 100.0% | 48.9% |
| 2388926 | 150.1.2.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › Ribonuc_red_sm | 0.89 | 85.0 | 6.46e-01 | 100.0% | 53.7% |
| 4340194 | 150.1.2.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › Ribonuc_red_sm | 0.89 | 85.0 | 6.40e-01 | 100.0% | 50.5% |
| 2846952 | 150.1.2.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › Ribonuc_red_sm | 0.88 | 84.0 | 6.31e-01 | 100.0% | 47.6% |
| 3723852 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.62 | 44.0 | 4.55e-01 | 95.1% | 77.0% |
| 4198585 | 5059.1.1.2 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › Multi_Drug_Res | 0.62 | 43.0 | 4.75e-01 | 83.3% | 85.8% |
| 3605285 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.61 | 46.0 | 4.66e-01 | 77.8% | 98.6% |
| 3432793 | 604.5.1.38 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › Gaa1 | 0.60 | 48.0 | 4.27e-01 | 84.7% | 98.5% |
| 3921890 | 603.2.1.1 ↗ | alpha bundles › STAT-like › STAT › STAT › STAT_alpha | 0.57 | 46.0 | 4.63e-01 | 97.2% | 83.4% |
| 4953715 | 5054.1.1.6 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › TrkH | 0.57 | 47.0 | 4.64e-01 | 86.8% | 96.0% |
| 3643042 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.57 | 49.0 | 4.37e-01 | 91.7% | 92.0% |
| 5009682 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.56 | 43.0 | 4.74e-01 | 81.9% | 95.8% |
| 3244169 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.56 | 43.0 | 3.71e-01 | 80.6% | 60.9% |
| 3735874 | 109.4.1.356 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fungal_trans | 0.55 | 50.0 | 3.50e-01 | 97.9% | 49.7% |
| 3738219 | 603.1.1.97 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin, SNARE | 0.55 | 47.0 | 4.15e-01 | 93.8% | 96.7% |
| 4426627 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.55 | 41.0 | 3.65e-01 | 78.5% | 63.8% |
| 3737954 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.54 | 45.0 | 4.51e-01 | 87.5% | 90.7% |
| 4986424 | 150.1.1.3 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Rubrerythrin | 0.54 | 40.0 | 4.06e-01 | 88.9% | 76.4% |
| 4965841 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.54 | 40.0 | 3.51e-01 | 77.1% | 85.0% |
| 3269514 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.54 | 41.0 | 3.57e-01 | 80.6% | 60.0% |
| 3165244 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.53 | 43.0 | 3.78e-01 | 87.5% | 58.1% |
| 3897111 | 109.4.1.562 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › CANIN | 0.53 | 48.0 | 3.34e-01 | 100.0% | 41.2% |
| 3566747 | 109.4.1.562 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › CANIN | 0.53 | 47.0 | 3.42e-01 | 99.3% | 41.0% |
| 3996121 | 109.4.1.1302 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF30363 | 0.53 | 39.0 | 3.16e-01 | 88.2% | 38.0% |
| 3206572 | 192.29.1.165 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › PF29336 | 0.53 | 43.0 | 4.42e-01 | 86.1% | 97.9% |
| 3218104 | 601.1.2.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) | 0.53 | 38.0 | 4.08e-01 | 77.1% | 87.2% |
| 3806998 | 601.1.1.97 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › DNA_repr_REX1B | 0.52 | 42.0 | 4.20e-01 | 84.7% | 93.3% |
| 3969605 | 174.1.1.7 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › DUF4345 | 0.52 | 40.0 | 4.20e-01 | 79.9% | 92.0% |
| 4026607 | 5050.1.1.28 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › BT1 | 0.52 | 40.0 | 3.45e-01 | 81.2% | 61.3% |
| 3744639 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.51 | 38.0 | 3.32e-01 | 77.8% | 60.3% |
| 3255335 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.50 | 38.0 | 3.37e-01 | 78.5% | 79.0% |
| 4014488 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.50 | 44.0 | 3.76e-01 | 97.2% | 93.8% |