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ribonucleotide_reductase_alpha_subunit
Euk-VirLymphocystis_disease_virus_Sa
ribonucleotide_reductase_alpha_subunit__YP_009342238__Lymphocystis_disease_virus_Sa__1898060
Identity
- Accession:
- YP_009342238 ↗
- Protein ID:
- ribonucleotide_reductase_alpha_subunit
- Kingdom:
- euk
Quality
91.7
mean pLDDT
Taxonomy
Bamfordvirae›
Nucleocytoviricota›
Megaviricetes›
Pimascovirales›
Iridoviridae›
Lymphocystivirus›
Lymphocystis_disease_virus_Sa
TaxID: 1898060
Cluster
View cluster (22 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 71-177_193-243
Domain cluster:
rep: IMGVR_UViG_3300042092_000730-3300042092-Ga0453238_010587_859_2079__D220-402
Pfam (2)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF02867.21 best | Ribonuc_red_lgC | 66.8 | 2.10e-18 | 69.6% | 22.3% |
| PF02867.21 | Ribonuc_red_lgC | 24.7 | 1.30e-05 | 30.4% | 6.5% |
D2
high
residues 414-470
Domain cluster:
rep: IMGVR_UViG_3300006567_000026-3300006567-Ga0099958_11086953__D213-268
CATH (5)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2jugA01 | 1.10.10.1830 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Non-ribosomal peptide synthase, adenylation domain | 0.53 | 37.0 | 3.74e-01 | 71.9% | 74.5% |
| 6cc0A01 | 3.30.450.80 | Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › Transcription factor LuxR-like, autoinducer-binding domain | 0.53 | 43.0 | 3.25e-01 | 100.0% | 56.7% |
| 7febA03 | 3.40.50.12790 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › FHIPEP family, domain 4 | 0.53 | 41.0 | 3.47e-01 | 84.2% | 88.0% |
| 2h84A02 | 3.40.47.10 | Alpha Beta › 3-Layer(aba) Sandwich › Peroxisomal Thiolase; Chain A, domain 1 › Thiolase/Chalcone synthase | 0.52 | 38.0 | 2.93e-01 | 82.5% | 84.5% |
| 5zjgA02 | 1.10.246.130 | Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › Gamma-glutamyltranspeptidase, large (L) subunit, C-terminal domain | 0.51 | 35.0 | 3.03e-01 | 77.2% | 74.1% |
ECOD (13)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2472944 | 2500.1.1.2 ↗ | a/b barrels › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ribonuc_red_lgC | 0.99 | 79.0 | 4.50e-01 | 100.0% | 10.6% |
| 4015532 | 2500.1.1.0 ↗ | a/b barrels › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel | 0.89 | 81.0 | 4.55e-01 | 100.0% | 9.9% |
| 4985374 | 2500.1.1.2 ↗ | a/b barrels › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ribonuc_red_lgC | 0.86 | 78.0 | 4.42e-01 | 100.0% | 9.9% |
| 996122 | 2500.1.1.2 ↗ | a/b barrels › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ribonuc_red_lgC | 0.86 | 78.0 | 4.40e-01 | 100.0% | 9.8% |
| 3823652 | 2500.1.1.2 ↗ | a/b barrels › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ribonuc_red_lgC | 0.86 | 77.0 | 4.38e-01 | 100.0% | 10.1% |
| 4993733 | 2500.1.1.0 ↗ | a/b barrels › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel | 0.83 | 73.0 | 4.15e-01 | 100.0% | 10.2% |
| 4994375 | 2500.1.1.0 ↗ | a/b barrels › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel | 0.80 | 72.0 | 4.17e-01 | 100.0% | 11.4% |
| 4934525 | 2500.1.1.2 ↗ | a/b barrels › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ribonuc_red_lgC | 0.77 | 70.0 | 3.99e-01 | 100.0% | 10.5% |
| 4990406 | 2500.1.1.2 ↗ | a/b barrels › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ribonuc_red_lgC | 0.77 | 66.0 | 3.74e-01 | 100.0% | 9.3% |
| 5074671 | 103.2.1.0 ↗ | alpha arrays › RuvA-C › ATP cone › ATP cone | 0.56 | 46.0 | 4.18e-01 | 98.2% | 84.7% |
| 5001059 | 103.2.1.2 ↗ | alpha arrays › RuvA-C › ATP cone › ATP cone › ATP-cone | 0.55 | 45.0 | 4.16e-01 | 98.2% | 90.0% |
| 3778614 | 233.1.1.5 ↗ | a+b two layers › MHC antigen-recognition domain › MHC antigen-recognition domain › MHC antigen-recognition domain › MHC_I_2 | 0.52 | 40.0 | 2.95e-01 | 93.0% | 83.1% |
| 3227340 | 214.1.1.1 ↗ | a+b two layers › SH2 › SH2 › SH2 › SH2 | 0.51 | 41.0 | 3.18e-01 | 98.2% | 76.0% |
D3
medium
residues 22-70_287-314
Domain cluster:
representative
CATH (3)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3h4cA02 | 1.10.472.110 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › | 0.56 | 44.0 | 4.00e-01 | 87.0% | 71.8% |
| 4m70I00 | 1.20.5.4130 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.54 | 44.0 | 3.95e-01 | 88.3% | 90.7% |
| 1mswD04 | 1.10.287.280 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.50 | 34.0 | 3.40e-01 | 85.7% | 67.9% |
ECOD (4)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3277072 | 1074.1.1.1 ↗ | alpha arrays › Alpha helical domain of ribonucleotide reductases › Alpha helical domain of ribonucleotide reductases › Alpha helical domain of ribonucleotide reductases › Ribonuc_red_lgN | 0.86 | 51.0 | 3.88e-01 | 88.3% | 29.7% |
| 4876272 | 142.1.1.3 ↗ | alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › Sigma70_r2 | 0.58 | 37.0 | 3.45e-01 | 80.5% | 50.5% |
| 3356517 | 102.1.1.20 ↗ | alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like › IGR | 0.55 | 41.0 | 4.25e-01 | 80.5% | 88.6% |
| 3251479 | 206.1.1.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase | 0.52 | 37.0 | 2.43e-01 | 76.6% | 48.8% |
D4
medium
residues 178-192_472-488_506-535
Domain cluster:
representative
CATH (1)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2lseA00 | 1.20.120.1360 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.53 | 36.0 | 3.12e-01 | 72.6% | 69.3% |
ECOD (7)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4426402 | 2006.1.4.1 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › XPG_N,XPG_I | 0.62 | 42.0 | 2.89e-01 | 71.0% | 66.8% |
| 3885497 | 904.1.1.23 ↗ | few secondary structure elements › B-box zinc-binding domain-like › B-box zinc-binding domain › B-box zinc-binding domain › TRIM_CC | 0.55 | 32.0 | 2.41e-01 | 80.6% | 23.3% |
| 3895580 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.54 | 31.0 | 2.46e-01 | 79.0% | 26.2% |
| 3209988 | 611.3.1.1 ↗ | alpha bundles › N-cbl like › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 › Med26 | 0.53 | 35.0 | 2.66e-01 | 79.0% | 29.7% |
| 3540735 | 904.1.1.22 ↗ | few secondary structure elements › B-box zinc-binding domain-like › B-box zinc-binding domain › B-box zinc-binding domain › zf-B_box, TRIM_CC | 0.53 | 32.0 | 2.23e-01 | 79.0% | 18.5% |
| 4976312 | 2006.1.4.13 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › PIN_9 | 0.52 | 35.0 | 2.89e-01 | 72.6% | 55.4% |
| 4374417 | 109.4.1.11 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PI3Ka | 0.51 | 36.0 | 2.36e-01 | 75.8% | 61.1% |
D5
medium
residues 267-286_315-410_489-505
Domain cluster:
rep: hypothetical_protein_FR483_N766L__YP_001426398__Paramecium_bursaria_Chlorella_virus_FR483__399781__D433-559_739-758
Pfam (2)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF02867.21 best | Ribonuc_red_lgC | 48.9 | 5.80e-13 | 54.9% | 12.2% |
| PF02867.21 | Ribonuc_red_lgC | 30.3 | 2.60e-07 | 30.8% | 7.1% |