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ribonucleotide_reductase_large_subunit

Euk-Vir

Acanthamoeba_polyphaga_moumouvirus

ribonucleotide_reductase_large_subunit__YP_007354486__Acanthamoeba_polyphaga_moumouvirus__1269028

Identity

Accession:
YP_007354486 ↗
Protein ID:
ribonucleotide_reductase_large_subunit
Kingdom:
euk

Quality

86.4 mean pLDDT

Taxonomy

Bamfordvirae› Nucleocytoviricota› Megaviricetes› Imitervirales› Mimiviridae› Moumouvirus› Acanthamoeba_polyphaga_moumouvirus

TaxID: 1269028

Cluster

View cluster (122 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 44-131
PDB
Domain cluster: rep: IMGVR_UViG_3300007266_000133-3300007266-Ga0101450_1063124__D4-90
CATH (39)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1c9bA01 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.68 53.0 5.14e-01 83.0% 77.3%
2fi1A02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.68 40.0 4.52e-01 83.0% 79.7%
1aisB01 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.67 52.0 5.05e-01 84.1% 75.8%
1zp2A02 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.67 54.0 5.00e-01 88.6% 75.0%
4rocA01 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.67 54.0 5.22e-01 96.6% 77.7%
2w96A02 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.66 58.0 5.35e-01 97.7% 77.0%
2nr4A02 1.20.58.290 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Hypothetical membrane protein ta0354_69_121. 0.66 33.0 3.98e-01 97.7% 72.4%
2hoqA02 1.10.150.520 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 0.66 48.0 4.99e-01 85.2% 84.8%
1dcnA03 1.10.40.30 Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase Protein R1; domain 1 › Fumarase/aspartase (C-terminal domain) 0.66 44.0 4.73e-01 84.1% 83.3%
2mtqA00 1.20.58.130 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.65 34.0 3.68e-01 95.5% 58.9%
2ivxB01 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.65 57.0 4.92e-01 100.0% 68.6%
1sxjE02 1.10.8.60 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.64 40.0 4.48e-01 70.5% 85.9%
5xs2B02 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.64 56.0 4.97e-01 100.0% 79.5%
1u84A00 1.10.340.20 Mainly Alpha › Orthogonal Bundle › Endonuclease III; domain 1 › Apc36109-like domain 0.64 45.0 4.70e-01 81.8% 81.5%
6z4xA01 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.63 53.0 4.42e-01 93.2% 69.0%
3zbhA00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.63 33.0 3.37e-01 96.6% 50.0%
3fblA00 1.20.58.800 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.63 46.0 4.75e-01 77.3% 91.5%
1s0pA01 1.25.40.330 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Adenylate cyclase-associated CAP, N-terminal domain 0.61 43.0 3.51e-01 73.9% 82.5%
2fnaA02 1.10.8.60 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.61 40.0 4.27e-01 75.0% 76.3%
2gfhA02 1.20.120.710 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Haloacid dehalogenase hydrolase-like domain 0.60 46.0 4.66e-01 81.8% 89.5%
3nz4B03 1.10.274.20 Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › Phenylalanine ammonia-lyase 1; domain 3 0.60 51.0 4.85e-01 95.5% 86.5%
1td6A03 1.10.472.40 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Hypothetical protein mg237 homolog; domain 3 0.60 43.0 4.32e-01 87.5% 73.9%
4ioeA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.59 32.0 3.27e-01 95.5% 51.7%
2q00B00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.59 44.0 4.00e-01 80.7% 74.6%
1biqA00 1.10.620.20 Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A 0.58 46.0 3.14e-01 86.4% 77.4%
2kjgA00 1.20.120.970 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.57 37.0 3.60e-01 81.8% 57.6%
1toaA01 3.40.50.1980 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nitrogenase molybdenum iron protein domain 0.57 44.0 3.84e-01 85.2% 94.4%
1zv1A00 1.10.8.10 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ubiquitin-associated (UBA) domain 0.56 34.0 3.90e-01 80.7% 88.1%
3fppA03 6.10.140.1990 Special › Helix non-globular › Helix Hairpins › 0.55 32.0 3.25e-01 94.3% 55.7%
3icxA01 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.55 31.0 3.35e-01 95.5% 65.3%
3h0dB02 1.10.1200.150 Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › Transcriptional repressor of class III stress genes, C-terminal domain 0.54 37.0 3.86e-01 88.6% 77.8%
2yogA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.54 39.0 3.06e-01 75.0% 80.2%
2fu2A00 1.20.1440.50 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Ta0600-like 0.54 39.0 4.07e-01 75.0% 93.6%
4g1tA02 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.54 32.0 3.71e-01 85.2% 85.2%
1ac1A00 3.40.30.10 Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin 0.54 40.0 3.17e-01 79.5% 53.2%
4o6kA00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.53 39.0 3.48e-01 79.5% 64.7%
4c97A02 3.30.70.1900 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.53 44.0 3.93e-01 96.6% 85.1%
1j7nA01 3.40.390.10 Alpha Beta › 3-Layer(aba) Sandwich › Collagenase (Catalytic Domain) › Collagenase (Catalytic Domain) 0.53 39.0 2.98e-01 100.0% 31.5%
1ujnA02 1.20.1090.10 Mainly Alpha › Up-down Bundle › Dehydroquinate synthase-like, alpha domain › Dehydroquinate synthase-like - alpha domain 0.52 42.0 3.46e-01 89.8% 71.4%
ECOD (62)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3394718 103.2.1.2 ↗ alpha arrays › RuvA-C › ATP cone › ATP cone › ATP-cone 0.88 60.0 7.09e-01 70.5% 100.0%
3486229 103.2.1.0 ↗ alpha arrays › RuvA-C › ATP cone › ATP cone 0.88 83.0 8.25e-01 100.0% 98.9%
3594048 103.2.1.0 ↗ alpha arrays › RuvA-C › ATP cone › ATP cone 0.87 81.0 8.12e-01 100.0% 100.0%
4312875 103.2.1.0 ↗ alpha arrays › RuvA-C › ATP cone › ATP cone 0.86 81.0 7.87e-01 100.0% 93.7%
4257906 103.2.1.2 ↗ alpha arrays › RuvA-C › ATP cone › ATP cone › ATP-cone 0.86 80.0 7.97e-01 98.9% 97.8%
3784313 103.2.1.2 ↗ alpha arrays › RuvA-C › ATP cone › ATP cone › ATP-cone 0.86 81.0 8.03e-01 100.0% 97.8%
2320584 103.2.1.2 ↗ alpha arrays › RuvA-C › ATP cone › ATP cone › ATP-cone 0.85 79.0 7.61e-01 100.0% 92.8%
3607359 103.2.1.1 ↗ alpha arrays › RuvA-C › ATP cone › ATP cone › Ribonuc_red_lgN 0.84 68.0 5.01e-01 84.1% 36.6%
4994194 103.2.1.2 ↗ alpha arrays › RuvA-C › ATP cone › ATP cone › ATP-cone 0.81 65.0 6.94e-01 94.3% 98.7%
2791177 103.2.1.2 ↗ alpha arrays › RuvA-C › ATP cone › ATP cone › ATP-cone 0.81 74.0 6.94e-01 100.0% 83.0%
4987957 103.2.1.0 ↗ alpha arrays › RuvA-C › ATP cone › ATP cone 0.80 65.0 6.94e-01 95.5% 100.0%
4485359 103.2.1.0 ↗ alpha arrays › RuvA-C › ATP cone › ATP cone 0.80 70.0 6.85e-01 95.5% 87.4%
1878968 103.2.1.2 ↗ alpha arrays › RuvA-C › ATP cone › ATP cone › ATP-cone 0.79 73.0 6.97e-01 100.0% 91.0%
4942297 103.2.1.2 ↗ alpha arrays › RuvA-C › ATP cone › ATP cone › ATP-cone 0.79 60.0 6.57e-01 89.8% 100.0%
4143596 103.2.1.0 ↗ alpha arrays › RuvA-C › ATP cone › ATP cone 0.79 63.0 6.31e-01 85.2% 95.6%
4948813 103.2.1.2 ↗ alpha arrays › RuvA-C › ATP cone › ATP cone › ATP-cone 0.78 65.0 6.80e-01 100.0% 98.8%
4987113 103.2.1.0 ↗ alpha arrays › RuvA-C › ATP cone › ATP cone 0.78 62.0 6.69e-01 95.5% 100.0%
4954173 103.2.1.2 ↗ alpha arrays › RuvA-C › ATP cone › ATP cone › ATP-cone 0.77 61.0 6.55e-01 95.5% 100.0%
4996564 103.2.1.0 ↗ alpha arrays › RuvA-C › ATP cone › ATP cone 0.76 67.0 6.84e-01 100.0% 98.8%
4952141 103.2.1.2 ↗ alpha arrays › RuvA-C › ATP cone › ATP cone › ATP-cone 0.76 61.0 6.41e-01 98.9% 96.2%
4466734 103.2.1.2 ↗ alpha arrays › RuvA-C › ATP cone › ATP cone › ATP-cone 0.75 69.0 6.30e-01 100.0% 76.5%
4507907 103.2.1.2 ↗ alpha arrays › RuvA-C › ATP cone › ATP cone › ATP-cone 0.73 64.0 6.53e-01 98.9% 97.6%
4946727 103.2.1.0 ↗ alpha arrays › RuvA-C › ATP cone › ATP cone 0.73 61.0 6.37e-01 98.9% 98.8%
4307412 181.1.1.27 ↗ alpha bundles › Domain of the SRP/SRP receptor G proteins-like › Domain of the SRP/SRP receptor G-proteins › Domain of the SRP/SRP receptor G-proteins › ATP-cone 0.73 64.0 6.56e-01 98.9% 98.8%
3597638 103.2.1.0 ↗ alpha arrays › RuvA-C › ATP cone › ATP cone 0.72 59.0 6.20e-01 93.2% 97.5%
5042563 103.2.1.2 ↗ alpha arrays › RuvA-C › ATP cone › ATP cone › ATP-cone 0.71 62.0 6.29e-01 98.9% 98.8%
4955004 4009.1.1.0 ↗ alpha bundles › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins 0.70 46.0 5.41e-01 77.3% 100.0%
3427839 103.2.1.0 ↗ alpha arrays › RuvA-C › ATP cone › ATP cone 0.70 61.0 6.19e-01 98.9% 98.8%
4975484 103.2.1.2 ↗ alpha arrays › RuvA-C › ATP cone › ATP cone › ATP-cone 0.70 63.0 4.31e-01 100.0% 99.3%
4341260 148.1.3.257 ↗ alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › DUF494 0.67 53.0 5.15e-01 94.3% 75.0%
3455739 181.1.1.0 ↗ alpha bundles › Domain of the SRP/SRP receptor G proteins-like › Domain of the SRP/SRP receptor G-proteins › Domain of the SRP/SRP receptor G-proteins 0.67 58.0 5.83e-01 98.9% 94.4%
4930122 2007.1.3.61 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › TfuA 0.67 55.0 4.17e-01 95.5% 37.6%
4929245 4953.1.1.0 ↗ beta barrels › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like 0.67 49.0 5.35e-01 96.6% 100.0%
4170883 103.7.1.2 ↗ alpha arrays › RuvA-C › Hypothetical protein MTH1615 › Hypothetical protein MTH1615 › DUF494 0.67 52.0 5.07e-01 94.3% 75.0%
5078120 4009.1.1.1 ↗ alpha bundles › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › ARMT1-like_dom 0.67 50.0 5.43e-01 90.9% 100.0%
4296803 4957.1.1.4 ↗ a+b complex topology › helical domain in yeast RNA-polymerases › third helical domain in yeast RNA-polymerase II beta-prime subunit › third helical domain in yeast RNA-polymerase II beta-prime subunit › DUF494 0.66 52.0 5.01e-01 94.3% 75.0%
3787521 101.1.10.1 ↗ alpha arrays › HTH › HTH › Cyclin-like › Cyclin_N 0.65 58.0 4.73e-01 100.0% 64.8%
3923604 101.1.10.14 ↗ alpha arrays › HTH › HTH › Cyclin-like › Cyclin_C_2 0.64 56.0 3.90e-01 97.7% 38.0%
4946843 4009.1.1.1 ↗ alpha bundles › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › ARMT1-like_dom 0.63 45.0 4.96e-01 83.0% 100.0%
3369538 3694.1.1.0 ↗ alpha bundles › Tail specific protease helical domain › Tail specific protease helical domain › Tail specific protease helical domain 0.62 48.0 4.98e-01 98.9% 92.5%
3281127 150.5.1.0 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like 0.61 34.0 3.39e-01 96.6% 51.1%
3342510 2004.1.1.56 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › NB-ARC 0.60 44.0 3.27e-01 78.4% 76.7%
3788827 103.4.1.0 ↗ alpha arrays › RuvA-C › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein 0.59 41.0 4.50e-01 93.2% 96.9%
2908177 633.11.1.1 ↗ alpha bundles › Bromodomain-like › Nqo1C-terminal domain-like › Nqo1C-terminal domain-like › NADH_4Fe-4S 0.58 43.0 4.45e-01 77.3% 86.4%
3588019 633.31.1.0 ↗ alpha bundles › Bromodomain-like › Four-helical bundle insertion domain in pyruvate-ferredoxin oxidoreductase › Four-helical bundle insertion domain in pyruvate-ferredoxin oxidoreductase 0.57 40.0 4.40e-01 72.7% 95.7%
3938318 4992.1.1.0 ↗ extended segments › RelB-like › RelB-like › RelB-like 0.56 32.0 2.88e-01 94.3% 40.0%
3282043 150.5.1.0 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like 0.56 31.0 3.23e-01 95.5% 54.1%
3987696 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.56 34.0 2.75e-01 95.5% 31.5%
3790837 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.56 31.0 2.73e-01 96.6% 34.1%
3389671 633.23.1.0 ↗ alpha bundles › Bromodomain-like › Claudin › Claudin 0.55 41.0 3.23e-01 78.4% 87.4%
3838401 192.10.1.0 ↗ alpha bundles › Long alpha-hairpin › DnaK suppressor protein DksA, alpha-hairpin domain › DnaK suppressor protein DksA, alpha-hairpin domain 0.55 39.0 3.81e-01 75.0% 71.0%
5001078 633.2.1.0 ↗ alpha bundles › Bromodomain-like › Carnobacteriocin B2 immunity protein › Carnobacteriocin B2 immunity protein 0.55 41.0 4.00e-01 78.4% 86.3%
None — 0.54 39.0 3.22e-01 75.0% 61.3%
3602825 633.12.1.0 ↗ alpha bundles › Bromodomain-like › Ta0600-like › Ta0600-like 0.54 46.0 4.08e-01 94.3% 69.2%
4433717 3788.1.1.22 ↗ alpha bundles › Viral accessory protein x (Vpx) / viral protein r (Vpr) › Viral accessory protein x (Vpx) / viral protein r (Vpr) › Viral accessory protein x (Vpx) / viral protein r (Vpr) › CowN 0.54 38.0 3.94e-01 73.9% 93.8%
4652008 181.2.1.1 ↗ alpha bundles › Domain of the SRP/SRP receptor G proteins-like › CtsR dimerization domain › CtsR dimerization domain › CtsR_C 0.53 37.0 3.94e-01 89.8% 83.3%
4445194 633.31.1.0 ↗ alpha bundles › Bromodomain-like › Four-helical bundle insertion domain in pyruvate-ferredoxin oxidoreductase › Four-helical bundle insertion domain in pyruvate-ferredoxin oxidoreductase 0.52 37.0 4.03e-01 73.9% 95.7%
3416261 371.1.1.0 ↗ few secondary structure elements › Phospholipase A2, PLA2 › Phospholipase A2, PLA2 › Phospholipase A2, PLA2 0.52 41.0 3.96e-01 95.5% 73.8%
3570651 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.52 40.0 3.98e-01 81.8% 88.4%
3776363 873.1.1.5 ↗ a+b complex topology › H-NOX domain › H-NOX domain › H-NOX domain › HNOB 0.51 43.0 3.34e-01 96.6% 80.9%
3758339 5086.1.1.65 ↗ alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › USHBP1_PDZ-bd 0.51 34.0 3.38e-01 96.6% 65.6%
3265237 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.50 42.0 2.32e-01 95.5% 6.2%
D2 medium residues 135-258
PDB
Domain cluster: rep: NC_007021.1__YP_238596.1__TwortORF045__00062__D44-158
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00317.27 best Ribonuc_red_lgN 75.7 3.30e-21 60.5% 96.1%
D3 medium residues 259-373_432-481_750-785
PDB
Domain cluster: rep: ribonucleotide_reductase_large_subunit__YP_009702292__African_swine_fever_virus__10497__D187-309_381-436_716-757
Pfam (3)
AccessionNameScoreE-valueQ covHMM cov
PF02867.21 best Ribonuc_red_lgC 134.4 7.20e-39 57.7% 22.1%
PF02867.21 Ribonuc_red_lgC 53.3 2.60e-14 26.4% 9.7%
PF02867.21 Ribonuc_red_lgC 30.5 2.20e-07 17.9% 6.9%
D4 medium residues 374-431
PDB
Domain cluster: rep: orf61__YP_009044444__Alcelaphine_gammaherpesvirus_2__138184__D298-350
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02867.21 best Ribonuc_red_lgC 50.4 2.00e-13 100.0% 11.1%
D5 medium residues 482-505_544-564_643-671_730-749
PDB
Domain cluster: rep: hypothetical_protein_APZ24_gp137__YP_009172628__Ostreococcus_lucimarinus_virus_2__1663208__D430-450_487-533_672-688
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02867.21 best Ribonuc_red_lgC 29.1 5.90e-07 35.1% 5.7%
D6 medium residues 506-543_565-586
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02867.21 best Ribonuc_red_lgC 27.1 2.30e-06 65.0% 7.1%
CATH (51)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3rq9A00 1.10.287.2500 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.69 52.0 4.78e-01 98.3% 62.8%
4fvmA06 1.10.287.690 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › B family DNA polymerase, finger domain 0.69 50.0 5.48e-01 98.3% 95.8%
1wa8A00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.66 51.0 4.31e-01 98.3% 50.5%
2fupA00 1.20.58.300 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › FlgN-like 0.65 44.0 3.48e-01 100.0% 33.9%
3na7A00 1.10.287.1490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.65 50.0 3.32e-01 98.3% 21.1%
2gv9A05 1.10.287.690 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › B family DNA polymerase, finger domain 0.65 48.0 4.92e-01 96.7% 81.4%
2cazD00 6.10.140.820 Special › Helix non-globular › Helix Hairpins › 0.65 48.0 4.88e-01 98.3% 80.0%
4l0rB00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.64 49.0 4.62e-01 98.3% 68.5%
2vixA02 1.10.150.630 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 0.64 37.0 3.30e-01 100.0% 39.3%
2e9xA01 1.20.58.1030 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.63 46.0 3.54e-01 98.3% 35.9%
3lssA01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.62 47.0 3.83e-01 100.0% 43.8%
4ioeA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.62 48.0 4.27e-01 93.3% 57.5%
3cqcA00 1.20.190.50 Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › 0.62 48.0 3.15e-01 100.0% 20.2%
2gd5A00 6.10.140.1230 Special › Helix non-globular › Helix Hairpins › 0.62 49.0 3.72e-01 86.7% 90.8%
1vcsA00 1.20.58.400 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins 0.62 47.0 3.96e-01 100.0% 49.0%
4lwsA00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.61 48.0 3.97e-01 91.7% 50.0%
1tjlA00 1.20.120.910 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › DksA, coiled-coil domain 0.60 48.0 3.68e-01 90.0% 66.9%
4e4eA01 1.10.287.990 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Fe,Mn superoxide dismutase (SOD) domain 0.60 46.0 4.32e-01 98.3% 69.0%
2h21A02 3.90.1420.10 Alpha Beta › Alpha-Beta Complex › set domain protein methyltransferase, domain 2 › Rubisco LSMT, substrate-binding domain 0.60 52.0 3.84e-01 100.0% 87.9%
2wzkA03 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.60 52.0 4.32e-01 100.0% 61.8%
3dfzA02 1.10.8.610 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › SirC, precorrin-2 dehydrogenase, C-terminal helical domain-like 0.59 40.0 3.78e-01 88.3% 58.1%
6ynwH01 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.58 45.0 4.23e-01 86.7% 68.9%
4m0mA03 1.20.1270.430 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.58 45.0 4.18e-01 93.3% 65.8%
6r1nA01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.57 44.0 3.65e-01 98.3% 47.6%
3d85C00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.57 51.0 3.92e-01 100.0% 60.9%
5jxxA02 1.20.1180.10 Mainly Alpha › Up-down Bundle › Udp N-acetylglucosamine O-acyltransferase; Domain 2 › Udp N-acetylglucosamine O-acyltransferase, C-terminal domain 0.57 37.0 3.62e-01 93.3% 60.6%
3edvB01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.57 42.0 3.28e-01 96.7% 36.0%
4wqoD00 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.56 49.0 3.80e-01 100.0% 55.3%
1s35A01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.56 44.0 3.69e-01 96.7% 48.5%
4cybD00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.56 46.0 3.43e-01 95.0% 74.3%
2e62A01 6.10.140.420 Special › Helix non-globular › Helix Hairpins › 0.56 44.0 4.65e-01 95.0% 100.0%
3r84B00 6.10.280.160 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Mediator of RNA polymerase II transcription subunit 22 0.56 49.0 4.49e-01 98.3% 83.7%
2kg7B00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.56 43.0 3.74e-01 86.7% 61.9%
2vs0A00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.55 48.0 4.35e-01 98.3% 86.6%
3ehfD01 1.20.5.1930 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.55 42.0 4.14e-01 96.7% 77.8%
4v1gA00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.55 45.0 4.00e-01 90.0% 98.8%
4ijjB00 1.20.120.910 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › DksA, coiled-coil domain 0.55 48.0 3.73e-01 98.3% 56.9%
3fd9A03 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.55 48.0 4.51e-01 98.3% 80.8%
5nl6A02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.54 48.0 3.96e-01 100.0% 76.9%
4errB00 1.20.58.1190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.54 40.0 3.62e-01 91.7% 56.6%
2ewfA02 1.20.1270.310 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.53 45.0 4.06e-01 93.3% 74.1%
2ic6A00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.53 46.0 4.41e-01 100.0% 85.9%
5svlA01 1.10.287.940 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › atp-gated p2x4 ion channel 0.53 41.0 3.98e-01 85.0% 91.2%
5dn6J00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.53 41.0 3.89e-01 86.7% 70.3%
3lphC00 6.10.140.630 Special › Helix non-globular › Helix Hairpins › 0.52 44.0 4.51e-01 91.7% 100.0%
1wcrA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.52 47.0 3.92e-01 100.0% 76.7%
1fs0G02 1.10.287.80 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain 0.51 41.0 3.75e-01 100.0% 64.0%
2b3tB01 6.10.140.1980 Special › Helix non-globular › Helix Hairpins › 0.51 43.0 4.21e-01 93.3% 92.3%
1gpjA03 1.10.1200.70 Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › Glutamyl tRNA-reductase dimerization domain 0.51 39.0 3.48e-01 81.7% 60.0%
3s64A00 1.10.225.10 Mainly Alpha › Orthogonal Bundle › NK-Lysin › Saposin-like 0.51 44.0 4.00e-01 100.0% 71.6%
6xm1A02 3.90.830.10 Alpha Beta › Alpha-Beta Complex › Syntaxin Binding Protein 1; Chain A, domain 2 › Sec1/Munc18 (SM) protein, domain 3a 0.51 38.0 3.19e-01 98.3% 44.2%
ECOD (56)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4984327 192.7.1.2 ↗ alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.65 49.0 4.09e-01 98.3% 46.7%
4034092 150.5.1.0 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like 0.65 48.0 4.47e-01 96.7% 64.0%
3559718 604.1.1.1 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.64 48.0 3.91e-01 98.3% 43.6%
3403227 192.8.1.465 ↗ alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › CHD5 0.64 48.0 3.92e-01 98.3% 43.6%
4977678 192.1.1.50 ↗ alpha bundles › Long alpha-hairpin › GreA transcript cleavage protein, N-terminal domain › GreA transcript cleavage protein, N-terminal domain › EMC3_TMCO1 0.64 49.0 3.59e-01 100.0% 31.2%
4473674 148.1.3.0 ↗ alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.63 50.0 4.14e-01 88.3% 80.0%
3193532 622.4.1.35 ↗ alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related › PF26729 0.63 51.0 4.44e-01 98.3% 58.9%
3282761 150.5.1.1 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › WXG100 0.62 48.0 4.11e-01 98.3% 53.7%
1495253 150.5.1.1 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › WXG100 0.61 48.0 3.97e-01 91.7% 50.0%
4156333 109.4.1.206 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › YfiO 0.61 46.0 3.48e-01 96.7% 33.3%
3507551 192.5.1.0 ↗ alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat 0.61 50.0 4.27e-01 100.0% 56.8%
222846 150.5.1.1 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › WXG100 0.61 47.0 4.05e-01 93.3% 53.8%
4939077 1079.1.1.0 ↗ alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA 0.60 50.0 3.53e-01 100.0% 79.1%
3953227 150.5.1.0 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like 0.60 47.0 4.01e-01 96.7% 52.0%
3827397 5069.1.3.0 ↗ alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits 0.60 45.0 3.62e-01 100.0% 41.7%
3422458 138.1.1.0 ↗ alpha arrays › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain 0.60 37.0 3.56e-01 95.0% 54.3%
3952558 3291.1.1.0 ↗ alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.59 50.0 3.98e-01 91.7% 72.2%
3362460 304.60.1.6 ↗ a+b two layers › Alpha-beta plaits › Ribosomal protein L10-like › Ribosomal protein L10-like › KIP1 0.59 46.0 4.34e-01 98.3% 69.3%
5060017 632.11.1.0 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like 0.58 47.0 4.62e-01 93.3% 81.5%
3939668 604.7.1.0 ↗ alpha bundles › Spectrin repeat-like › Tubulin chaperone cofactor A › Tubulin chaperone cofactor A 0.58 48.0 3.25e-01 90.0% 40.5%
4956683 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.58 50.0 4.27e-01 100.0% 76.0%
4630202 5041.1.1.1 ↗ extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › ATP-synt_C 0.57 45.0 3.99e-01 86.7% 91.0%
4977468 5058.1.1.16 ↗ alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1 0.57 44.0 3.89e-01 85.0% 64.4%
3952510 150.5.1.0 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like 0.57 49.0 4.60e-01 96.7% 88.0%
3919843 604.1.1.124 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin_6 0.56 49.0 3.79e-01 96.7% 62.3%
3764851 192.8.1.0 ↗ alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.56 42.0 3.71e-01 100.0% 55.6%
3853566 604.5.1.0 ↗ alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) 0.55 45.0 3.62e-01 88.3% 62.6%
4109908 5041.1.1.1 ↗ extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › ATP-synt_C 0.55 44.0 3.90e-01 86.7% 62.4%
4223385 150.5.1.1 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › WXG100 0.55 48.0 4.09e-01 98.3% 85.0%
5070731 632.18.1.0 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › hypothetical protein PA2901 › hypothetical protein PA2901 0.55 45.0 4.07e-01 95.0% 66.3%
3848917 3939.1.1.0 ↗ alpha duplicates or obligate multimers › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain 0.55 47.0 4.25e-01 98.3% 74.1%
3187995 603.1.1.3 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins › V-SNARE 0.55 49.0 3.98e-01 100.0% 70.9%
5062160 632.23.1.0 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Helical linker domain in nicking endonuclease N.BspD6I › Helical linker domain in nicking endonuclease N.BspD6I 0.54 43.0 4.08e-01 88.3% 72.9%
3333417 5041.1.1.1 ↗ extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › ATP-synt_C 0.54 44.0 3.85e-01 93.3% 60.0%
3787792 5041.1.1.1 ↗ extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › ATP-synt_C 0.54 44.0 3.83e-01 93.3% 60.0%
4973840 4323.1.1.0 ↗ alpha bundles › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C 0.53 40.0 3.02e-01 90.0% 33.8%
2799599 5041.1.1.1 ↗ extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › ATP-synt_C 0.53 43.0 3.88e-01 91.7% 67.4%
3958870 150.5.1.0 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like 0.53 43.0 3.73e-01 91.7% 84.2%
5060845 632.22.1.0 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.53 43.0 4.19e-01 91.7% 81.5%
4402843 604.1.1.20 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › AKNA 0.52 46.0 3.74e-01 100.0% 79.1%
5069815 632.11.1.0 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like 0.52 42.0 3.81e-01 95.0% 63.5%
5059274 632.11.1.0 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like 0.52 38.0 3.73e-01 85.0% 70.8%
3249830 5086.1.1.0 ↗ alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.52 44.0 3.54e-01 98.3% 96.8%
3594525 603.1.1.0 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.52 45.0 3.88e-01 100.0% 82.0%
5016654 632.11.1.0 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like 0.52 39.0 3.78e-01 86.7% 72.3%
5035480 159.1.2.4 ↗ alpha bundles › all-alpha NTP pyrophosphatases › all-alpha NTP pyrophosphatases › MazG-related › MazG-like 0.52 44.0 3.54e-01 96.7% 50.0%
3170639 103.1.1.0 ↗ alpha arrays › RuvA-C › RuvA-C, UBA, CRAL/TRIO-N, HBS1 › UBA-like domain 0.52 46.0 4.11e-01 100.0% 90.6%
4511746 150.5.1.51 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › WXG100_2 0.51 44.0 3.19e-01 96.7% 42.3%
4983596 632.22.1.0 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.51 41.0 4.03e-01 93.3% 80.0%
5064089 632.11.1.0 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like 0.51 42.0 3.98e-01 93.3% 74.7%
4029043 101.11.1.0 ↗ alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 0.51 44.0 3.94e-01 100.0% 85.6%
5061323 632.11.1.0 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like 0.51 41.0 3.99e-01 91.7% 80.0%
5060020 632.11.1.0 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like 0.51 41.0 4.03e-01 95.0% 81.5%
3491128 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.51 44.0 3.48e-01 100.0% 75.4%
3500970 603.1.1.152 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins › AATF-Che1 0.51 44.0 3.44e-01 100.0% 65.2%
5062727 632.18.1.0 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › hypothetical protein PA2901 › hypothetical protein PA2901 0.50 36.0 3.41e-01 83.3% 64.3%
D7 medium residues 587-642
PDB
Domain cluster: rep: putative_ribonucleoside-diphosphate_reductase_protein__YP_294186__Emiliania_huxleyi_virus_86__181082__D538-588
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02867.21 best Ribonuc_red_lgC 45.6 5.80e-12 100.0% 10.1%
D8 medium residues 672-729_786-817
PDB
Domain cluster: rep: ORF61__YP_009173941__Felis_catus_gammaherpesvirus_1__1452540__D602-680
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02867.21 best Ribonuc_red_lgC 32.3 6.00e-08 97.8% 11.1%