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ribonucleotide_reductase_large_subunit

Euk-Vir

Murine_roseolovirus

ribonucleotide_reductase_large_subunit__YP_009344851__Murine_roseolovirus__1940555

Identity

Accession:
YP_009344851 ↗
Protein ID:
ribonucleotide_reductase_large_subunit
Kingdom:
euk

Quality

71.3 mean pLDDT

Taxonomy

Heunggongvirae› Peploviricota› Herviviricetes› Herpesvirales› Orthoherpesviridae› Roseolovirus› Murine_roseolovirus

TaxID: 1940555

Cluster

View cluster (26 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 98-275
PDB
Domain cluster: rep: protein_UL27__YP_004940053__Aotine_betaherpesvirus_1__50290__D178-261_284-374
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF05999.17 best Herpes_U5 47.6 1.70e-12 82.6% 32.8%
D2 medium residues 11-97_278-313
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF05999.17 best Herpes_U5 30.0 3.70e-07 65.8% 13.5%
CATH (33)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2vzbB00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.72 53.0 4.78e-01 77.2% 91.6%
4d8mA01 1.20.190.10 Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › Pesticidal crystal protein, N-terminal domain 0.71 65.0 5.33e-01 98.4% 79.6%
1aepA00 1.20.120.20 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein 0.68 48.0 4.44e-01 72.4% 58.8%
2yjkC00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.68 47.0 4.34e-01 71.5% 91.1%
1z6oA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.68 51.0 4.22e-01 78.9% 75.5%
1hu3A00 1.25.40.180 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.67 45.0 3.82e-01 89.4% 41.2%
1t72A02 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.65 45.0 5.01e-01 70.7% 100.0%
2clbA01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.65 45.0 4.13e-01 70.7% 92.5%
4dloB02 1.25.40.610 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.65 50.0 5.11e-01 86.2% 84.6%
4it4A02 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.64 46.0 5.22e-01 79.7% 98.9%
3edvB01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.64 48.0 4.70e-01 78.0% 83.8%
8h72B01 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.64 44.0 3.30e-01 70.7% 43.4%
1quuA01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.64 47.0 4.75e-01 78.0% 89.7%
2xheA04 1.25.40.60 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.63 40.0 4.14e-01 82.1% 66.1%
3myvA01 1.25.40.390 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.63 48.0 3.84e-01 79.7% 100.0%
6wv5A01 1.20.1440.130 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › VKOR domain 0.62 44.0 4.27e-01 73.2% 69.1%
5dckA00 1.10.1200.30 Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › Retrovirus capsid C-terminal domain 0.61 34.0 4.28e-01 75.6% 93.0%
8h6qD01 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.61 42.0 3.16e-01 70.7% 42.0%
1u5pA01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.60 44.0 4.63e-01 75.6% 100.0%
1t72A01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.60 45.0 4.61e-01 77.2% 94.0%
2b0hA01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.59 41.0 4.14e-01 72.4% 72.7%
5mdtA00 1.25.40.90 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.57 49.0 4.60e-01 92.7% 94.1%
1r0dA00 1.20.1410.10 Mainly Alpha › Up-down Bundle › I/LWEQ domain › I/LWEQ domain 0.56 42.0 3.63e-01 78.0% 51.8%
1jadA00 1.20.1230.10 Mainly Alpha › Up-down Bundle › Phospholipase C Beta; Chain: A › Phospholipase C beta, distal C-terminal domain 0.56 39.0 3.18e-01 72.4% 88.4%
1iyhB02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.55 42.0 4.49e-01 87.0% 93.5%
1yz5B00 1.20.190.20 Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › 14-3-3 domain 0.55 50.0 4.03e-01 99.2% 67.2%
1aabA00 1.10.30.10 Mainly Alpha › Orthogonal Bundle › DNA Binding (I), subunit A › High mobility group box domain 0.54 27.0 3.29e-01 99.2% 73.5%
4dk4B00 1.10.4010.10 Mainly Alpha › Orthogonal Bundle › all-alpha NTP pyrophosphatase fold › Type II deoxyuridine triphosphatase 0.53 38.0 3.20e-01 74.8% 53.5%
1sgmA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.52 41.0 3.67e-01 85.4% 94.0%
3lomA00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.51 42.0 3.31e-01 91.9% 76.4%
5zw7A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.51 43.0 4.02e-01 91.1% 90.8%
3v1vA00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.50 45.0 3.38e-01 100.0% 68.8%
3juiA00 1.25.40.180 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.50 38.0 3.42e-01 87.8% 55.7%
ECOD (47)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3612519 5086.1.1.0 ↗ alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.71 52.0 4.99e-01 76.4% 87.1%
3632024 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.69 46.0 4.54e-01 87.8% 62.2%
3585432 604.1.1.98 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin_Anc-1 0.69 50.0 5.15e-01 74.0% 88.7%
3208948 4121.1.1.0 ↗ a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like 0.68 61.0 5.05e-01 96.7% 76.3%
3221759 604.3.1.0 ↗ alpha bundles › Spectrin repeat-like › BAG domain › BAG domain 0.68 52.0 4.49e-01 80.5% 73.2%
3404048 604.6.1.0 ↗ alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain 0.68 50.0 4.89e-01 75.6% 85.4%
3512309 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.67 46.0 3.42e-01 84.6% 28.7%
3724935 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.66 49.0 4.68e-01 77.2% 94.5%
3579784 604.1.1.1 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.66 49.0 4.93e-01 78.0% 93.6%
4017168 150.1.1.114 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › PF30036 0.65 49.0 4.56e-01 78.9% 75.3%
4342803 604.12.1.0 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.65 50.0 5.23e-01 79.7% 95.5%
3574755 604.1.1.1 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.65 45.0 4.71e-01 70.7% 92.7%
3918068 604.1.1.1 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.65 48.0 4.93e-01 76.4% 94.8%
3513988 604.1.1.1 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.64 48.0 4.93e-01 78.0% 93.3%
3848559 109.4.1.1216 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › ARM_KNTC1_1st 0.64 43.0 3.81e-01 90.2% 45.4%
5076586 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.64 44.0 4.91e-01 70.7% 100.0%
3615596 3758.1.1.0 ↗ alpha bundles › Bacterial hemolysins-like › Bacterial hemolysins › Bacterial hemolysins 0.64 56.0 4.26e-01 92.7% 71.5%
4034192 603.1.1.11 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins › DUF3169 0.64 49.0 4.17e-01 81.3% 70.0%
4022168 4121.1.1.0 ↗ a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like 0.63 58.0 4.38e-01 100.0% 84.5%
3749998 604.1.1.1 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.63 47.0 4.80e-01 77.2% 93.3%
3569017 604.1.1.1 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.63 47.0 4.30e-01 78.0% 70.6%
3231554 3937.1.1.2 ↗ alpha bundles › Connexin 26 › Connexin 26 › Connexin 26 › Innexin 0.63 48.0 3.46e-01 80.5% 59.1%
3729699 4121.1.1.0 ↗ a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like 0.62 56.0 4.26e-01 97.6% 90.7%
3605744 603.1.1.0 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.62 46.0 4.03e-01 78.0% 57.9%
3491130 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.62 45.0 4.37e-01 74.8% 100.0%
3868371 604.1.1.1 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.62 46.0 4.04e-01 77.2% 87.8%
4012748 4121.1.1.0 ↗ a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like 0.61 53.0 3.94e-01 93.5% 78.1%
3180672 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.61 51.0 4.29e-01 91.9% 67.0%
3257076 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.61 54.0 5.13e-01 96.7% 94.5%
3578921 3937.1.1.2 ↗ alpha bundles › Connexin 26 › Connexin 26 › Connexin 26 › Innexin 0.61 45.0 3.22e-01 77.2% 62.1%
3484930 604.1.1.1 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.61 45.0 4.77e-01 76.4% 100.0%
3230188 633.23.1.0 ↗ alpha bundles › Bromodomain-like › Claudin › Claudin 0.61 47.0 4.44e-01 82.1% 72.5%
3998554 109.54.1.1 ↗ alpha superhelices › Repetitive alpha hairpins › C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13 › C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13 › Utp12 0.60 48.0 4.71e-01 94.3% 78.5%
3911777 633.10.1.15 ↗ alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like › Transmemb_17 0.60 44.0 4.31e-01 76.4% 69.6%
3188384 601.14.1.1 ↗ alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin › Hemerythrin 0.60 43.0 3.85e-01 74.8% 69.7%
3661058 109.4.1.1316 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Suf, HAT_PRP39_N, HAT_PRP39_C 0.59 48.0 3.47e-01 86.2% 52.7%
3956796 101.1.2.49 ↗ alpha arrays › HTH › HTH › winged helix domain › PadR,Vir_act_alpha_C 0.59 49.0 4.29e-01 90.2% 87.6%
3526587 109.4.1.839 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Maestro_HEAT 0.59 46.0 3.30e-01 82.1% 44.3%
3832604 219.1.1.0 ↗ a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases 0.57 49.0 3.13e-01 97.6% 18.3%
3452617 5059.1.1.24 ↗ alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › PUNUT 0.57 50.0 3.67e-01 96.7% 98.2%
4945181 3651.1.1.1 ↗ alpha bundles › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › IF-2B 0.56 42.0 4.12e-01 77.2% 76.9%
3934654 604.12.1.0 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.53 39.0 3.51e-01 78.0% 70.0%
4105334 1075.3.1.1 ↗ alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC importer transmembrane domain fold › Type I ABC importer transmembrane domain fold › BPD_transp_1 0.51 43.0 3.59e-01 94.3% 86.4%
3731804 5058.1.1.37 ↗ alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › PF25886 0.51 44.0 4.17e-01 95.9% 100.0%
3884861 109.1.1.1 ↗ alpha superhelices › Repetitive alpha hairpins › Glutathione S-transferase (GST)-C › Glutathione S-transferase (GST)-C › GST_C 0.51 40.0 3.58e-01 86.2% 75.6%
3185802 7015.1.1.0 ↗ alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain 0.50 43.0 4.18e-01 95.1% 83.7%
3802509 7015.1.1.0 ↗ alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain 0.50 42.0 3.97e-01 91.1% 79.3%