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ribonucleotide_reductase_large_subunit
Euk-VirAkhmeta_virus
ribonucleotide_reductase_large_subunit__YP_010085528__Akhmeta_virus__2200830
Identity
- Accession:
- YP_010085528 ↗
- Protein ID:
- ribonucleotide_reductase_large_subunit
- Kingdom:
- euk
Quality
92.1
mean pLDDT
Taxonomy
Bamfordvirae›
Nucleocytoviricota›
Pokkesviricetes›
Chitovirales›
Poxviridae›
Orthopoxvirus›
Orthopoxvirus_akhmetapox
TaxID: 2200830
Cluster
View cluster (122 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 2-88
Domain cluster:
rep: IMGVR_UViG_3300007266_000133-3300007266-Ga0101450_1063124__D4-90
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF03477.22 best | ATP-cone | 62.1 | 8.40e-17 | 100.0% | 96.6% |
D2
medium
residues 92-168_182-195
Domain cluster:
rep: NC_007021.1__YP_238596.1__TwortORF045__00062__D44-158
D3
medium
residues 169-181_196-218_441-536_594-609_662-702
Domain cluster:
rep: rr1__YP_009552690__Operophtera_brumata_nucleopolyhedrovirus__1046267__D445-618_684-706
Pfam (2)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF02867.21 best | Ribonuc_red_lgC | 123.1 | 1.90e-35 | 57.7% | 19.7% |
| PF02867.21 | Ribonuc_red_lgC | 28.5 | 8.60e-07 | 21.7% | 6.9% |
D4
medium
residues 219-334_395-440_703-746
Domain cluster:
rep: ribonucleotide_reductase_large_subunit__YP_009702292__African_swine_fever_virus__10497__D187-309_381-436_716-757
Pfam (3)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF02867.21 best | Ribonuc_red_lgC | 155.0 | 3.90e-45 | 57.3% | 21.9% |
| PF02867.21 | Ribonuc_red_lgC | 60.0 | 2.50e-16 | 23.8% | 9.3% |
| PF02867.21 | Ribonuc_red_lgC | 31.8 | 8.80e-08 | 18.0% | 6.9% |
D5
medium
residues 335-394
Domain cluster:
rep: orf61__YP_009044444__Alcelaphine_gammaherpesvirus_2__138184__D298-350
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF02867.21 best | Ribonuc_red_lgC | 55.6 | 5.40e-15 | 100.0% | 11.5% |
D6
medium
residues 537-593
Domain cluster:
rep: putative_ribonucleoside-diphosphate_reductase_protein__YP_294186__Emiliania_huxleyi_virus_86__181082__D538-588
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF02867.21 best | Ribonuc_red_lgC | 49.3 | 4.50e-13 | 100.0% | 10.9% |
D7
medium
residues 610-661
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF02867.21 best | Ribonuc_red_lgC | 45.3 | 7.20e-12 | 100.0% | 9.3% |
CATH (16)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2xfvA00 | 3.10.260.30 | Alpha Beta › Roll › Mlu1-box Binding Protein; DNA-binding Domain › | 0.57 | 41.0 | 3.37e-01 | 80.8% | 89.8% |
| 1go4A00 | 3.30.900.10 | Alpha Beta › 2-Layer Sandwich › Cell Cycle, Spindle Assembly Checkpoint Protein; Chain A › HORMA domain | 0.56 | 38.0 | 2.57e-01 | 71.2% | 72.4% |
| 4nrjB01 | 3.90.20.10 | Alpha Beta › Alpha-Beta Complex › Hemagglutinin Ectodomain; Chain B › | 0.55 | 38.0 | 2.83e-01 | 75.0% | 59.6% |
| 7l9pK01 | 3.30.900.10 | Alpha Beta › 2-Layer Sandwich › Cell Cycle, Spindle Assembly Checkpoint Protein; Chain A › HORMA domain | 0.55 | 38.0 | 3.00e-01 | 75.0% | 85.7% |
| 6ui4A02 | 1.20.58.530 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.54 | 34.0 | 2.52e-01 | 84.6% | 21.9% |
| 3wxyA02 | 3.40.47.10 | Alpha Beta › 3-Layer(aba) Sandwich › Peroxisomal Thiolase; Chain A, domain 1 › Thiolase/Chalcone synthase | 0.53 | 40.0 | 2.97e-01 | 82.7% | 85.7% |
| 2wr7C01 | 3.90.20.10 | Alpha Beta › Alpha-Beta Complex › Hemagglutinin Ectodomain; Chain B › | 0.53 | 38.0 | 2.49e-01 | 78.8% | 93.9% |
| 3v7iA02 | 3.40.47.10 | Alpha Beta › 3-Layer(aba) Sandwich › Peroxisomal Thiolase; Chain A, domain 1 › Thiolase/Chalcone synthase | 0.53 | 40.0 | 2.94e-01 | 84.6% | 85.0% |
| 2bolB02 | 2.60.40.790 | Mainly Beta › Sandwich › Immunoglobulin-like › | 0.53 | 41.0 | 3.18e-01 | 90.4% | 46.9% |
| 1hh5A00 | 3.90.10.10 | Alpha Beta › Alpha-Beta Complex › Cytochrome C3 › Cytochrome C3 | 0.52 | 34.0 | 3.22e-01 | 86.5% | 51.5% |
| 2innB00 | 1.10.620.20 | Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A | 0.51 | 37.0 | 2.19e-01 | 80.8% | 63.3% |
| 2zxiA03 | 1.10.10.1800 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG/GidA | 0.51 | 41.0 | 3.46e-01 | 96.2% | 52.6% |
| 5wzoA00 | 1.20.90.10 | Mainly Alpha › Up-down Bundle › Phospholipase A2 › Phospholipase A2 domain | 0.50 | 35.0 | 2.73e-01 | 75.0% | 51.2% |
| 2h84A02 | 3.40.47.10 | Alpha Beta › 3-Layer(aba) Sandwich › Peroxisomal Thiolase; Chain A, domain 1 › Thiolase/Chalcone synthase | 0.50 | 37.0 | 2.79e-01 | 80.8% | 85.1% |
| 4jaqA02 | 3.40.47.10 | Alpha Beta › 3-Layer(aba) Sandwich › Peroxisomal Thiolase; Chain A, domain 1 › Thiolase/Chalcone synthase | 0.50 | 38.0 | 2.89e-01 | 84.6% | 84.1% |
| 2fn0B00 | 3.60.120.10 | Alpha Beta › 4-Layer Sandwich › Anthranilate synthase › Anthranilate synthase | 0.50 | 40.0 | 2.47e-01 | 100.0% | 75.0% |
ECOD (25)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3823652 | 2500.1.1.2 ↗ | a/b barrels › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ribonuc_red_lgC | 0.89 | 84.0 | 4.64e-01 | 100.0% | 9.2% |
| 4015532 | 2500.1.1.0 ↗ | a/b barrels › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel | 0.88 | 82.0 | 4.56e-01 | 100.0% | 9.0% |
| 996122 | 2500.1.1.2 ↗ | a/b barrels › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ribonuc_red_lgC | 0.83 | 76.0 | 4.25e-01 | 100.0% | 8.9% |
| 4990406 | 2500.1.1.2 ↗ | a/b barrels › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ribonuc_red_lgC | 0.82 | 73.0 | 4.07e-01 | 100.0% | 9.0% |
| 4985374 | 2500.1.1.2 ↗ | a/b barrels › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ribonuc_red_lgC | 0.80 | 72.0 | 4.02e-01 | 100.0% | 9.2% |
| 4993733 | 2500.1.1.0 ↗ | a/b barrels › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel | 0.77 | 70.0 | 3.95e-01 | 100.0% | 9.5% |
| 4994375 | 2500.1.1.0 ↗ | a/b barrels › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel | 0.77 | 70.0 | 3.96e-01 | 100.0% | 10.4% |
| 4934525 | 2500.1.1.2 ↗ | a/b barrels › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ribonuc_red_lgC | 0.75 | 69.0 | 3.87e-01 | 100.0% | 9.5% |
| 4298539 | 2500.1.1.2 ↗ | a/b barrels › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ribonuc_red_lgC | 0.71 | 65.0 | 3.63e-01 | 98.1% | 22.1% |
| 1515981 | 7581.1.1.6 ↗ | a/b three-layered sandwiches › Thiolase-like › Thiolase-like › Thiolase-like › Chal_sti_synt_C | 0.55 | 40.0 | 2.98e-01 | 80.8% | 84.9% |
| 4778883 | 10.5.1.1 ↗ | beta sandwiches › jelly-roll › Viral protein domain › Viral protein domain › Hemagglutinin | 0.55 | 38.0 | 2.79e-01 | 76.9% | 58.8% |
| 3675966 | 70.3.1.22 ↗ | beta barrels › beta-clip › SET domain-like › SET domain-like › Inhibitor_I29 | 0.55 | 35.0 | 2.69e-01 | 73.1% | 28.3% |
| 3779 | 4967.1.1.2 ↗ | alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › RdRP_1 | 0.54 | 34.0 | 2.81e-01 | 86.5% | 30.8% |
| 3440733 | 7581.1.1.6 ↗ | a/b three-layered sandwiches › Thiolase-like › Thiolase-like › Thiolase-like › Chal_sti_synt_C | 0.54 | 39.0 | 2.85e-01 | 80.8% | 84.6% |
| 3488042 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.54 | 38.0 | 2.25e-01 | 75.0% | 21.0% |
| 3963911 | 101.1.2.55 ↗ | alpha arrays › HTH › HTH › winged helix domain › SMC_ScpB | 0.53 | 33.0 | 2.89e-01 | 78.8% | 37.5% |
| 217102 | 7581.1.1.0 ↗ | a/b three-layered sandwiches › Thiolase-like › Thiolase-like › Thiolase-like | 0.53 | 40.0 | 2.94e-01 | 84.6% | 85.0% |
| 5027863 | 101.1.2.55 ↗ | alpha arrays › HTH › HTH › winged helix domain › SMC_ScpB | 0.52 | 33.0 | 2.96e-01 | 73.1% | 40.0% |
| 4551803 | 101.1.2.55 ↗ | alpha arrays › HTH › HTH › winged helix domain › SMC_ScpB | 0.52 | 32.0 | 2.81e-01 | 71.2% | 35.3% |
| 158313 | 4967.1.1.2 ↗ | alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › RdRP_1 | 0.52 | 39.0 | 3.05e-01 | 84.6% | 94.5% |
| 3959072 | 7581.1.1.0 ↗ | a/b three-layered sandwiches › Thiolase-like › Thiolase-like › Thiolase-like | 0.52 | 38.0 | 2.93e-01 | 82.7% | 88.6% |
| 3593732 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.51 | 36.0 | 2.11e-01 | 76.9% | 61.6% |
| 3419966 | 7581.1.1.26 ↗ | a/b three-layered sandwiches › Thiolase-like › Thiolase-like › Thiolase-like › Chal_sti_synt_N, Chal_sti_synt_C, ACP_syn_III | 0.51 | 42.0 | 2.55e-01 | 98.1% | 46.2% |
| 3944944 | 101.1.2.261 ↗ | alpha arrays › HTH › HTH › winged helix domain › MC2 | 0.51 | 30.0 | 2.88e-01 | 100.0% | 46.2% |
| 1516005 | 7581.1.1.6 ↗ | a/b three-layered sandwiches › Thiolase-like › Thiolase-like › Thiolase-like › Chal_sti_synt_C | 0.50 | 37.0 | 2.79e-01 | 80.8% | 85.1% |