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ribonucleotide_reductase_small_chain

Euk-Vir

Marseillevirus_marseillevirus

ribonucleotide_reductase_small_chain__YP_003407004__Marseillevirus_marseillevirus__694581

Identity

Accession:
YP_003407004 ↗
Protein ID:
ribonucleotide_reductase_small_chain
Kingdom:
euk

Quality

82.4 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 11-124
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00268.28 best Ribonuc_red_sm 83.0 3.40e-23 100.0% 40.9%
CATH (35)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1h0oA00 1.10.620.20 Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A 0.96 92.0 6.54e-01 100.0% 39.2%
1cnt200 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.86 58.0 5.53e-01 98.2% 60.0%
3r2kA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.80 63.0 5.62e-01 100.0% 61.0%
2c41C01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.79 68.0 6.14e-01 100.0% 69.1%
2incA00 1.10.620.20 Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A 0.79 73.0 4.71e-01 100.0% 36.3%
3rm5B02 1.20.910.10 Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like 0.79 73.0 5.73e-01 100.0% 78.6%
1rtwB00 1.20.910.10 Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like 0.78 73.0 5.86e-01 100.0% 80.3%
5ux2B01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.78 61.0 4.88e-01 87.7% 43.9%
4cmyA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.77 62.0 5.45e-01 100.0% 58.9%
3t9jA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.76 65.0 5.93e-01 98.2% 70.8%
8d7hD01 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.76 64.0 5.46e-01 100.0% 57.8%
2yw6B00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.76 67.0 6.07e-01 100.0% 71.3%
2pybA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.76 66.0 5.92e-01 100.0% 69.5%
3unoE00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.75 60.0 5.22e-01 99.1% 56.9%
3e6sA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.75 61.0 5.45e-01 100.0% 62.3%
1s3qG00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.74 59.0 5.22e-01 100.0% 58.9%
1lb3A00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.74 61.0 5.30e-01 100.0% 59.3%
5hyhA00 1.10.620.20 Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A 0.74 68.0 5.01e-01 100.0% 62.7%
3hhcC00 1.20.1250.60 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › Interferon lambda 0.74 51.0 4.63e-01 100.0% 53.6%
3kwoA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.73 64.0 5.79e-01 100.0% 71.1%
1m56C02 1.20.120.80 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle 0.73 50.0 4.13e-01 70.2% 70.9%
2yevA03 1.20.120.80 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle 0.72 50.0 4.19e-01 70.2% 75.5%
1za0A00 1.10.620.20 Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A 0.70 57.0 4.39e-01 85.1% 86.8%
2qf9A01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.70 65.0 5.79e-01 100.0% 73.1%
6yz2A01 1.20.120.350 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C 0.70 48.0 4.76e-01 70.2% 88.3%
4mrsA01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.70 58.0 4.13e-01 90.4% 77.2%
2fupA00 1.20.58.300 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › FlgN-like 0.67 50.0 4.80e-01 76.3% 78.0%
3wmeA01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.67 56.0 4.04e-01 90.4% 80.9%
2cmrA00 1.20.58.1860 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.66 52.0 4.41e-01 84.2% 91.7%
1fewA00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.65 48.0 4.13e-01 76.3% 65.9%
6g94A00 1.20.950.20 Mainly Alpha › Up-down Bundle › Fumarate Reductase Cytochrome B subunit › Transmembrane di-heme cytochromes, Chain C 0.64 46.0 4.00e-01 73.7% 95.9%
6adqG01 1.20.120.80 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle 0.61 43.0 3.70e-01 71.9% 79.8%
4w8pA02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.57 47.0 4.54e-01 89.5% 76.2%
6gy8A01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.56 51.0 3.60e-01 98.2% 77.7%
3hwcA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.55 49.0 4.04e-01 100.0% 76.7%
ECOD (33)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4603349 150.1.2.1 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › Ribonuc_red_sm 0.96 93.0 6.21e-01 100.0% 31.8%
3274715 150.1.2.1 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › Ribonuc_red_sm 0.96 89.0 6.92e-01 100.0% 50.7%
3969049 601.4.1.3 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › 4HB_MCP_1 0.78 55.0 4.78e-01 71.9% 77.0%
4628639 150.1.1.59 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Coat_F 0.77 53.0 5.82e-01 70.2% 86.3%
3453619 601.4.1.12 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › DNA_repr_REX1B 0.76 53.0 4.72e-01 71.1% 86.5%
5079825 604.5.1.1 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU_div 0.73 56.0 4.41e-01 79.8% 68.2%
4963973 1203.1.2.0 alpha bundles › Shroom domain 2 › Shroom domain 2 › Human SD2 0.72 60.0 5.17e-01 86.8% 69.4%
3888265 601.4.1.12 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › DNA_repr_REX1B 0.72 50.0 4.62e-01 70.2% 95.0%
3904130 1203.1.2.1 alpha bundles › Shroom domain 2 › Shroom domain 2 › Human SD2 › ASD2 0.71 58.0 5.77e-01 86.8% 97.5%
3677594 3291.1.1.110 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › DUF641 0.71 49.0 4.59e-01 71.1% 58.6%
3883945 1203.1.2.1 alpha bundles › Shroom domain 2 › Shroom domain 2 › Human SD2 › ASD2 0.70 57.0 4.75e-01 86.0% 61.1%
3458146 5059.1.1.8 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › Mg_trans_NIPA 0.70 56.0 5.41e-01 86.0% 76.2%
3436831 601.4.1.52 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › Auxin_canalis 0.69 52.0 4.99e-01 100.0% 69.2%
4969096 3926.1.1.0 alpha bundles › V-type proton ATPase subunit D › V-type proton ATPase subunit D › V-type proton ATPase subunit D 0.69 57.0 4.41e-01 89.5% 68.0%
4948636 604.5.1.1 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU_div 0.69 52.0 4.21e-01 78.9% 72.9%
3375617 192.5.1.30 alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat › DUF641 0.69 46.0 5.46e-01 100.0% 98.8%
3249720 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.68 47.0 4.57e-01 71.1% 82.3%
3671851 5086.1.1.47 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › Auxin_canalis 0.67 48.0 4.56e-01 100.0% 62.2%
5035080 5069.1.1.0 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes 0.67 54.0 4.93e-01 87.7% 92.9%
3362472 605.1.1.132 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › DUF641 0.67 52.0 5.37e-01 87.7% 85.5%
4057957 603.5.1.1 alpha bundles › STAT-like › FlgN-like › FlgN-like › FlgN 0.67 51.0 4.74e-01 79.8% 74.3%
3704239 604.5.1.0 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) 0.66 47.0 3.78e-01 73.7% 64.9%
3819179 632.7.1.62 alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain › DUF641 0.66 52.0 4.81e-01 88.6% 67.1%
3294587 1134.1.2.2 alpha bundles › C-terminal helical domain of alanine-tRNA ligase › C-terminal helical domain of alanine-tRNA ligase › Archaeal C-Ala helical domain › DUF641 0.65 51.0 4.89e-01 88.6% 72.3%
3697399 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.63 44.0 3.98e-01 72.8% 80.0%
3584854 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.61 50.0 4.88e-01 90.4% 80.0%
3508614 601.1.1.1 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Vinculin 0.59 45.0 4.16e-01 80.7% 89.7%
4356766 5069.1.1.15 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Cytochrom_C_asm 0.58 47.0 4.14e-01 87.7% 90.9%
3452483 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.58 49.0 4.19e-01 93.0% 56.2%
3649632 611.9.1.4 alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain › Rx_N 0.57 51.0 4.76e-01 95.6% 85.7%
5039785 632.22.1.200 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › PF26119 0.57 44.0 4.82e-01 86.0% 100.0%
3990381 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.54 41.0 3.42e-01 79.8% 48.5%
3273611 4177.1.1.1 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH 0.52 47.0 3.49e-01 98.2% 78.9%
D2 medium residues 125-251
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00268.28 best Ribonuc_red_sm 76.8 2.60e-21 92.9% 41.3%
CATH (14)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4a5dB00 1.10.620.20 Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A 0.93 78.0 6.18e-01 89.8% 47.4%
1h0oA00 1.10.620.20 Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A 0.93 82.0 6.03e-01 96.1% 40.3%
2aniA00 1.10.620.20 Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A 0.92 85.0 6.05e-01 95.3% 38.5%
5olkB01 1.10.620.20 Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A 0.90 86.0 6.41e-01 100.0% 47.0%
1biqA00 1.10.620.20 Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A 0.89 84.0 5.96e-01 100.0% 39.1%
4bmoA00 1.10.620.20 Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A 0.82 76.0 5.68e-01 100.0% 43.1%
6eboA00 1.10.620.20 Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A 0.82 76.0 5.61e-01 100.0% 41.2%
4mudC00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.73 58.0 4.80e-01 88.2% 48.6%
1w0bA01 1.20.58.420 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › AHSP 0.65 43.0 4.92e-01 79.5% 92.4%
3behB01 1.20.120.540 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels 0.59 38.0 4.02e-01 98.4% 70.9%
2rd3D00 1.20.910.10 Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like 0.58 45.0 3.83e-01 83.5% 82.6%
3dbyL00 1.20.1260.120 Mainly Alpha › Up-down Bundle › Ferritin › Protein of unknown function DUF2935 0.57 46.0 3.72e-01 88.2% 92.3%
4nwpD00 1.20.1200.10 Mainly Alpha › Up-down Bundle › Hypothetical Protein Ta1238; Chain: A; › Cobalamin adenosyltransferase-like 0.53 36.0 3.44e-01 99.2% 58.4%
2rkkA01 1.25.40.270 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Vacuolar protein sorting-associated protein vta1 0.52 38.0 3.60e-01 76.4% 92.3%
ECOD (14)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3470297 150.1.2.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase 0.94 87.0 6.10e-01 100.0% 36.1%
162837 150.1.2.1 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › Ribonuc_red_sm 0.93 83.0 6.11e-01 96.9% 40.6%
4603349 150.1.2.1 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › Ribonuc_red_sm 0.93 86.0 5.94e-01 100.0% 34.1%
151585 150.1.2.1 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › Ribonuc_red_sm 0.93 80.0 6.01e-01 92.1% 42.2%
4026999 150.1.2.1 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › Ribonuc_red_sm 0.91 83.0 5.96e-01 99.2% 38.4%
3968133 150.1.2.1 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › Ribonuc_red_sm 0.90 86.0 6.02e-01 100.0% 36.9%
4481595 150.1.2.1 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › Ribonuc_red_sm 0.90 86.0 6.10e-01 100.0% 40.3%
3386562 150.1.2.1 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › Ribonuc_red_sm 0.90 86.0 6.13e-01 100.0% 40.0%
2388926 150.1.2.1 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › Ribonuc_red_sm 0.90 86.0 6.26e-01 100.0% 44.7%
4488174 150.1.2.1 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › Ribonuc_red_sm 0.89 85.0 6.05e-01 100.0% 40.6%
3509792 5069.1.1.3 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Cyt_bd_oxida_I 0.62 45.0 3.28e-01 74.8% 96.4%
3584463 5054.1.1.8 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans_2 0.58 42.0 3.49e-01 74.8% 68.4%
5012612 5058.1.1.0 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.52 42.0 3.71e-01 89.0% 91.8%
5033111 1075.5.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE 0.51 42.0 3.55e-01 89.8% 77.8%