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ribonucleotide_reductase_subunit_1

Euk-Vir

Aotine_betaherpesvirus_1

ribonucleotide_reductase_subunit_1__YP_004940071__Aotine_betaherpesvirus_1__50290

Identity

Accession:
YP_004940071 ↗
Protein ID:
ribonucleotide_reductase_subunit_1
Kingdom:
euk

Quality

81.2 mean pLDDT

Taxonomy

Heunggongvirae› Peploviricota› Herviviricetes› Herpesvirales› Orthoherpesviridae› Cytomegalovirus› Aotine_betaherpesvirus_1

TaxID: 50290

Cluster

View cluster (25 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 331-526
PDB
Domain cluster: rep: IMGVR_UViG_3300042092_000730-3300042092-Ga0453238_010587_859_2079__D220-402
CATH (35)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1r1rA02 3.20.70.20 Alpha Beta › Alpha-Beta Barrel › Anaerobic Ribonucleotide-triphosphate Reductase Large Chain › 0.88 85.0 6.06e-01 100.0% 43.2%
4mzyA02 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.71 43.0 4.68e-01 87.8% 70.2%
2l5oA00 3.40.30.10 Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin 0.59 30.0 3.45e-01 88.8% 62.7%
1gz1A00 3.20.20.40 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › 1, 4-beta cellobiohydrolase 0.57 51.0 4.11e-01 95.9% 82.9%
2eixA02 3.40.50.80 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module 0.56 36.0 4.23e-01 95.4% 91.9%
4n5hX00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.56 50.0 4.28e-01 96.4% 88.3%
1fkwA00 3.20.20.140 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Metal-dependent hydrolases 0.56 52.0 4.25e-01 100.0% 80.8%
2gjlA00 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.55 43.0 3.69e-01 81.6% 65.7%
7bipB01 3.20.20.30 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Luciferase-like domain 0.55 51.0 4.30e-01 100.0% 69.7%
4l9yD00 3.20.20.60 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Phosphoenolpyruvate-binding domains 0.55 51.0 4.57e-01 99.5% 79.6%
4us5C00 3.20.20.30 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Luciferase-like domain 0.55 51.0 4.24e-01 100.0% 64.5%
4l80D00 3.20.20.60 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Phosphoenolpyruvate-binding domains 0.54 50.0 4.17e-01 100.0% 62.8%
3c3jA01 3.40.50.10490 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 0.54 37.0 3.76e-01 99.5% 69.6%
3jy6D02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.54 31.0 3.68e-01 96.9% 81.5%
2a3nA01 3.40.50.10490 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 0.54 33.0 3.59e-01 98.0% 72.2%
1wp0A00 3.40.30.10 Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin 0.53 33.0 3.59e-01 87.8% 72.5%
1twdA00 3.20.20.380 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Copper homeostasis (CutC) domain 0.53 44.0 4.16e-01 100.0% 73.9%
1ur4A00 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.53 48.0 3.86e-01 100.0% 89.4%
1eucA02 3.40.50.261 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Succinyl-CoA synthetase domains 0.53 42.0 4.54e-01 96.4% 97.6%
3dxiA00 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.52 49.0 4.20e-01 100.0% 73.6%
2oejA02 3.20.20.110 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Ribulose bisphosphate carboxylase, large subunit, C-terminal domain 0.52 49.0 4.25e-01 100.0% 73.3%
4fo5A00 3.40.30.10 Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin 0.52 31.0 3.65e-01 96.4% 83.1%
1nvmA01 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.52 49.0 4.34e-01 100.0% 81.9%
3paoB00 3.20.20.140 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Metal-dependent hydrolases 0.52 48.0 4.09e-01 100.0% 84.1%
5vxsA01 3.20.20.60 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Phosphoenolpyruvate-binding domains 0.52 47.0 4.26e-01 99.5% 74.7%
3kl0A02 3.20.20.80 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases 0.52 44.0 3.92e-01 91.8% 68.2%
3fwzA00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.51 32.0 3.75e-01 89.3% 87.1%
3a21B01 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.51 47.0 4.10e-01 100.0% 86.3%
3etkA02 3.20.20.140 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Metal-dependent hydrolases 0.51 47.0 4.13e-01 100.0% 81.9%
1hf2A01 3.30.750.50 Alpha Beta › 2-Layer Sandwich › Transcription Regulator spoIIAA › Cell-division inhibitor MinC, N-terminal domain 0.51 26.0 3.50e-01 76.5% 100.0%
3eleA02 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.51 39.0 3.70e-01 97.4% 66.8%
2b7nA02 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.51 35.0 4.01e-01 89.8% 94.5%
2bb0A02 3.20.20.140 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Metal-dependent hydrolases 0.50 46.0 4.03e-01 100.0% 83.6%
5ej8A03 3.40.50.970 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains 0.50 40.0 3.96e-01 90.8% 78.1%
3v7nA02 3.40.50.1100 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.50 45.0 4.32e-01 96.4% 97.3%
ECOD (38)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3500621 2500.1.1.2 ↗ a/b barrels › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ribonuc_red_lgC 0.90 87.0 6.11e-01 100.0% 42.7%
4067125 2500.1.1.2 ↗ a/b barrels › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ribonuc_red_lgC 0.88 85.0 6.04e-01 100.0% 43.7%
3590466 2500.1.1.2 ↗ a/b barrels › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ribonuc_red_lgC 0.87 84.0 5.83e-01 100.0% 39.4%
2504767 2500.1.1.2 ↗ a/b barrels › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ribonuc_red_lgC 0.86 83.0 5.92e-01 100.0% 41.7%
3958480 2500.1.1.2 ↗ a/b barrels › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ribonuc_red_lgC 0.86 83.0 6.52e-01 100.0% 58.1%
4990406 2500.1.1.2 ↗ a/b barrels › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ribonuc_red_lgC 0.84 81.0 5.54e-01 100.0% 39.2%
5063882 1074.1.1.6 ↗ alpha arrays › Alpha helical domain of ribonucleotide reductases › Alpha helical domain of ribonucleotide reductases › Alpha helical domain of ribonucleotide reductases › Ribonuc_red_lgC 0.81 73.0 5.78e-01 100.0% 51.5%
4934525 2500.1.1.2 ↗ a/b barrels › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ribonuc_red_lgC 0.80 75.0 5.22e-01 100.0% 34.7%
3972491 2500.1.1.2 ↗ a/b barrels › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ribonuc_red_lgC 0.80 77.0 5.32e-01 100.0% 39.0%
4985374 2500.1.1.2 ↗ a/b barrels › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ribonuc_red_lgC 0.80 74.0 5.09e-01 100.0% 32.7%
4564490 2500.1.1.2 ↗ a/b barrels › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ribonuc_red_lgC 0.79 75.0 5.23e-01 100.0% 34.5%
4937370 2500.1.1.2 ↗ a/b barrels › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ribonuc_red_lgC 0.79 76.0 5.17e-01 100.0% 40.8%
5040104 2500.1.1.2 ↗ a/b barrels › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ribonuc_red_lgC 0.78 73.0 5.23e-01 100.0% 37.6%
4993733 2500.1.1.0 ↗ a/b barrels › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel 0.77 72.0 5.03e-01 98.0% 76.5%
4994375 2500.1.1.0 ↗ a/b barrels › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel 0.76 71.0 5.10e-01 98.0% 92.4%
4979159 2002.4.1.3 ↗ a/b barrels › TIM beta/alpha-barrel › Nicotinate/Quinolinate PRTase C-terminal domain-like › Nicotinate/Quinolinate PRTase C-terminal domain-like › NAPRTase_C 0.70 44.0 3.68e-01 88.3% 38.4%
4087732 2500.1.1.0 ↗ a/b barrels › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel 0.64 61.0 4.40e-01 100.0% 45.7%
3057642 2007.1.3.11 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › VpsR 0.64 37.0 4.49e-01 86.2% 85.6%
3275621 2500.1.1.0 ↗ a/b barrels › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel 0.63 60.0 4.43e-01 100.0% 48.0%
3612136 2003.1.1.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains 0.59 38.0 4.51e-01 88.8% 94.8%
3192181 7514.1.1.0 ↗ a/b three-layered sandwiches › Ferredoxin reductase-like, C-terminal NADP-linked domain › Ferredoxin reductase-like, C-terminal NADP-linked domain › Ferredoxin reductase-like, C-terminal NADP-linked domain 0.58 40.0 4.35e-01 93.4% 83.6%
4938804 2007.3.1.0 ↗ a/b three-layered sandwiches › Flavodoxin-like › Succinyl-CoA synthetase domains › Succinyl-CoA synthetase domains 0.57 37.0 4.46e-01 86.2% 95.5%
3943155 2002.1.1.151 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Glyco_hydro_53 0.56 49.0 3.93e-01 92.9% 67.4%
4167562 2003.1.6.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › Tubulin nucleotide-binding domain-like 0.55 40.0 4.33e-01 98.0% 86.5%
3839820 2002.1.1.67 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Pro_dh 0.55 51.0 4.14e-01 100.0% 71.5%
3178067 2002.1.1.56 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Dus 0.55 47.0 3.89e-01 91.3% 74.5%
4999481 2002.1.1.8 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Cellulase 0.55 50.0 4.38e-01 99.0% 83.1%
3960636 2002.1.1.0 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels 0.54 50.0 4.54e-01 100.0% 84.9%
3640401 7514.1.1.3 ↗ a/b three-layered sandwiches › Ferredoxin reductase-like, C-terminal NADP-linked domain › Ferredoxin reductase-like, C-terminal NADP-linked domain › Ferredoxin reductase-like, C-terminal NADP-linked domain › NAD_binding_6 0.54 38.0 4.14e-01 95.4% 84.8%
3967119 2002.1.1.108 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › NMO 0.54 48.0 4.01e-01 100.0% 57.2%
5005623 2002.1.1.120 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Radical_SAM 0.54 47.0 3.81e-01 94.9% 98.4%
3843311 2002.1.1.220 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Menorin 0.53 50.0 4.43e-01 100.0% 75.6%
3940676 2005.1.1.14 ↗ a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › PAPS_reduct 0.53 35.0 3.38e-01 96.4% 57.8%
None — 0.52 48.0 4.01e-01 100.0% 78.5%
5011725 2002.1.1.0 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels 0.52 48.0 4.57e-01 100.0% 90.9%
3881151 2006.1.1.41 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › 5-nucleotidase 0.52 31.0 3.84e-01 88.3% 93.6%
3492560 2003.1.6.6 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › Tubulin nucleotide-binding domain-like › Misat_Tub_SegII+Tubulin_3 0.51 45.0 4.07e-01 98.0% 93.8%
165390 2002.1.1.66 ↗ a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › DHquinase_I 0.50 46.0 4.49e-01 100.0% 89.8%
D2 medium residues 108-190
PDB
Domain cluster: representative
CATH (6)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3ckcA02 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.73 51.0 3.94e-01 72.3% 79.1%
2ra1A03 1.20.58.770 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.73 50.0 5.50e-01 71.1% 100.0%
4i17A00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.69 44.0 3.17e-01 73.5% 23.7%
3n5lA03 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.62 34.0 3.90e-01 95.2% 75.4%
1wkbA03 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.61 48.0 4.31e-01 88.0% 90.9%
2kg7B00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.58 35.0 3.36e-01 91.6% 52.6%
ECOD (7)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3382545 109.4.1.1262 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_1, PPR_2, PPR_long 0.70 48.0 3.44e-01 71.1% 31.4%
5010482 140.1.1.5 ↗ alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon_1 0.63 54.0 4.22e-01 100.0% 72.3%
4234978 3456.1.1.1 ↗ extended segments › NADH-quinone oxidoreductase subunit A › NADH-quinone oxidoreductase subunit A › NADH-quinone oxidoreductase subunit A › Oxidored_q4 0.60 35.0 3.10e-01 92.8% 39.2%
3724383 109.4.1.583 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › DNA_pol_phi 0.59 48.0 3.55e-01 92.8% 40.0%
4568066 2004.1.1.5 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran 0.57 50.0 3.59e-01 100.0% 75.0%
5006023 3456.1.1.1 ↗ extended segments › NADH-quinone oxidoreductase subunit A › NADH-quinone oxidoreductase subunit A › NADH-quinone oxidoreductase subunit A › Oxidored_q4 0.53 33.0 3.01e-01 90.4% 44.3%
3577058 101.1.1.3 ↗ alpha arrays › HTH › HTH › Three-helical HTH › Myb_DNA-binding 0.50 35.0 3.74e-01 73.5% 88.6%
D3 medium residues 191-330
PDB
Domain cluster: rep: ribonucleotide_reductase_subunit_1__YP_401655__Human_gammaherpesvirus_4__10376__D15-179